BR112018001863A2 - ?processo para a preparação de n- [2 - [[[1- (4-clorofenil) -1h-pirazol-3-il] oxi] metil] fenil]? - Google Patents
?processo para a preparação de n- [2 - [[[1- (4-clorofenil) -1h-pirazol-3-il] oxi] metil] fenil]?Info
- Publication number
- BR112018001863A2 BR112018001863A2 BR112018001863A BR112018001863A BR112018001863A2 BR 112018001863 A2 BR112018001863 A2 BR 112018001863A2 BR 112018001863 A BR112018001863 A BR 112018001863A BR 112018001863 A BR112018001863 A BR 112018001863A BR 112018001863 A2 BR112018001863 A2 BR 112018001863A2
- Authority
- BR
- Brazil
- Prior art keywords
- methyl
- pyrazol
- chlorophenyl
- oxy
- phenyl
- Prior art date
Links
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 title 1
- 125000003854 p-chlorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1Cl 0.000 title 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 title 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 2
- 150000001298 alcohols Chemical class 0.000 abstract 1
- 229940100198 alkylating agent Drugs 0.000 abstract 1
- 239000002168 alkylating agent Substances 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 239000002798 polar solvent Substances 0.000 abstract 1
- HZRSNVGNWUDEFX-UHFFFAOYSA-N pyraclostrobin Chemical compound COC(=O)N(OC)C1=CC=CC=C1COC1=NN(C=2C=CC(Cl)=CC=2)C=C1 HZRSNVGNWUDEFX-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/04—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
- C07D231/24—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms having sulfone or sulfonic acid radicals in the molecule
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Catalysts (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
a presente invenção refere-se a um processo para a preparação de n- [2 - [[[1- (4-clorofenil) -1h-pirazol-3-il] oxi] metil] fenil] -n-metoxicarbamato de metila (i) cristalino, compreendendo a) reação de um composto da fórmula ii (ii) com um agente de alquilação na presença de uma base na presença de um solvente polar selecionado de álcoois e cetonas b) a adição de água.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562202920P | 2015-08-10 | 2015-08-10 | |
US62/202,920 | 2015-08-10 | ||
EP15188491.3 | 2015-10-06 | ||
EP15188491 | 2015-10-06 | ||
PCT/EP2016/068365 WO2017025377A1 (en) | 2015-08-10 | 2016-08-02 | A novel process for preparing crystalline methyl N-[2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl]phenyl]-N-methoxycarbamate |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018001863A2 true BR112018001863A2 (pt) | 2018-09-18 |
BR112018001863B1 BR112018001863B1 (pt) | 2023-11-14 |
Family
ID=54260685
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018001863-5A BR112018001863B1 (pt) | 2015-08-10 | 2016-08-02 | Processo para a preparação de n-[2-[[[1-(4-clorofenil)- 1h-pirazol-3-il] oxi]metil]fenil] |
Country Status (7)
Country | Link |
---|---|
US (1) | US10273216B2 (pt) |
EP (1) | EP3334712B1 (pt) |
CN (1) | CN107848981A (pt) |
BR (1) | BR112018001863B1 (pt) |
CA (1) | CA2994399C (pt) |
MX (1) | MX2018001731A (pt) |
WO (1) | WO2017025377A1 (pt) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR112017024258A2 (pt) * | 2015-05-14 | 2018-07-24 | Adama Makhteshim Ltd | processo para preparar um composto pirazólico de hidroxilamina. |
WO2018035685A1 (en) | 2016-08-22 | 2018-03-01 | Basf Se | Process for preparing substituted biphenyls |
AU2017353264B2 (en) | 2016-11-04 | 2021-08-05 | Basf Se | Process for purification of pyrazolpyridazines |
CN106543066B (zh) * | 2016-11-11 | 2018-12-21 | 深圳市新阳唯康科技有限公司 | 一种唑菌胺酯晶型及其制备方法 |
CN106631965A (zh) * | 2016-12-21 | 2017-05-10 | 深圳市新阳唯康科技有限公司 | 一种唑菌胺酯新晶型及其制备方法 |
CN107021927B (zh) * | 2017-03-28 | 2020-05-29 | 天津大学 | 一种吡唑醚菌酯晶型及其制备方法 |
CN111655668B (zh) * | 2018-01-17 | 2024-02-13 | Gsp作物科学有限公司 | 用于制备吡唑醚菌酯的改进方法 |
CN109438354A (zh) * | 2018-12-07 | 2019-03-08 | 新沂市永诚化工有限公司 | 一种高纯度吡唑醚菌酯的制备方法 |
CN110407751A (zh) * | 2019-07-16 | 2019-11-05 | 武汉科技大学 | N-甲氧基苯基氨基甲酸甲酯的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100512227B1 (ko) | 1997-09-05 | 2005-09-05 | 바스프 악티엔게젤샤프트 | 헤테로(방향족)히드록실아민의 제조 방법 |
AR054777A1 (es) | 2005-06-20 | 2007-07-18 | Basf Ag | Modificaciones cristalinas de piraclostrobina |
CN102399190A (zh) * | 2011-12-20 | 2012-04-04 | 河南中医学院 | 一种经济型合成吡唑醚菌酯及其方法 |
CN104211641B (zh) * | 2014-08-19 | 2016-08-24 | 山东康乔生物科技有限公司 | 一种吡唑醚菌酯的合成工艺 |
CN104592117A (zh) | 2015-01-13 | 2015-05-06 | 安徽国星生物化学有限公司 | 一种吡唑醚菌酯的合成方法 |
-
2016
- 2016-08-02 US US15/751,349 patent/US10273216B2/en active Active
- 2016-08-02 CN CN201680046402.2A patent/CN107848981A/zh active Pending
- 2016-08-02 WO PCT/EP2016/068365 patent/WO2017025377A1/en active Application Filing
- 2016-08-02 CA CA2994399A patent/CA2994399C/en active Active
- 2016-08-02 EP EP16745475.0A patent/EP3334712B1/en active Active
- 2016-08-02 BR BR112018001863-5A patent/BR112018001863B1/pt active IP Right Grant
- 2016-08-02 MX MX2018001731A patent/MX2018001731A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP3334712B1 (en) | 2019-10-09 |
US10273216B2 (en) | 2019-04-30 |
MX2018001731A (es) | 2018-05-16 |
BR112018001863B1 (pt) | 2023-11-14 |
EP3334712A1 (en) | 2018-06-20 |
CA2994399C (en) | 2023-10-17 |
WO2017025377A1 (en) | 2017-02-16 |
CN107848981A (zh) | 2018-03-27 |
CA2994399A1 (en) | 2017-02-16 |
US20180230104A1 (en) | 2018-08-16 |
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/08/2016, OBSERVADAS AS CONDICOES LEGAIS |