BR112018000660A2 - peptídeos anti-inflamatórios e seu uso - Google Patents
peptídeos anti-inflamatórios e seu usoInfo
- Publication number
- BR112018000660A2 BR112018000660A2 BR112018000660-2A BR112018000660A BR112018000660A2 BR 112018000660 A2 BR112018000660 A2 BR 112018000660A2 BR 112018000660 A BR112018000660 A BR 112018000660A BR 112018000660 A2 BR112018000660 A2 BR 112018000660A2
- Authority
- BR
- Brazil
- Prior art keywords
- antiinflammatory
- region
- fragment
- amino acid
- methionine
- Prior art date
Links
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 4
- 239000012634 fragment Substances 0.000 abstract 4
- 235000001014 amino acid Nutrition 0.000 abstract 3
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 235000018417 cysteine Nutrition 0.000 abstract 3
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 abstract 3
- 229930182817 methionine Natural products 0.000 abstract 3
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 2
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 2
- 125000000729 N-terminal amino-acid group Chemical group 0.000 abstract 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 abstract 2
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 2
- 235000003704 aspartic acid Nutrition 0.000 abstract 2
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 2
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 2
- 235000018102 proteins Nutrition 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 125000001433 C-terminal amino-acid group Chemical group 0.000 abstract 1
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 abstract 1
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 abstract 1
- 239000004473 Threonine Substances 0.000 abstract 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Birds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Immunology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15177013.8 | 2015-07-16 | ||
| EP15177013.8A EP3118215A1 (en) | 2015-07-16 | 2015-07-16 | Anti-inflammatory peptides, and uses thereof |
| EP15177017.9 | 2015-07-16 | ||
| EP15177017.9A EP3118216A1 (en) | 2015-07-16 | 2015-07-16 | Cellular growth and proliferation promoting peptides, and uses thereof |
| PCT/EP2016/067090 WO2017009484A1 (en) | 2015-07-16 | 2016-07-18 | Anti-inflammatory peptides, and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018000660A2 true BR112018000660A2 (pt) | 2019-05-14 |
Family
ID=56686757
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018000660-2A BR112018000660A2 (pt) | 2015-07-16 | 2016-07-18 | peptídeos anti-inflamatórios e seu uso |
Country Status (12)
| Country | Link |
|---|---|
| US (4) | US10463591B2 (enExample) |
| EP (3) | EP3954700A1 (enExample) |
| JP (3) | JP2018523703A (enExample) |
| KR (3) | KR102576571B1 (enExample) |
| CN (2) | CN108348568B (enExample) |
| AU (2) | AU2016293129B2 (enExample) |
| BR (1) | BR112018000660A2 (enExample) |
| CA (1) | CA2992378A1 (enExample) |
| DK (1) | DK3322430T3 (enExample) |
| ES (1) | ES2806989T3 (enExample) |
| MX (2) | MX377692B (enExample) |
| WO (1) | WO2017009484A1 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110381976A (zh) * | 2016-12-05 | 2019-10-25 | 努里塔斯有限公司 | 包括肽wkdeagkplvk的组合物 |
| JP7340314B2 (ja) * | 2020-01-15 | 2023-09-07 | Tdk株式会社 | 米に含まれるタンパク質の含有量を測定する方法 |
| KR102354916B1 (ko) * | 2020-02-11 | 2022-01-26 | 주식회사 쓰리빅스 | 신규 펩타이드 3ps_i014 및 이의 용도 |
| FR3114744B1 (fr) * | 2020-10-02 | 2024-01-05 | Basf Beauty Care Solutions France Sas | Nouvelle utilisation d’un peptide pour améliorer le confort de la peau et/ou des muqueuses et/ou l’apparence des phanères |
| US20240043474A1 (en) * | 2020-12-16 | 2024-02-08 | Ajou University Industry-Academic Cooperation Foundation | Anti-inflammatory peptide for preventing or treating atopic dermatitis |
| CN114478702B (zh) * | 2022-04-06 | 2023-12-12 | 中南林业科技大学 | 一种米糠来源短肽及其在治疗皮肤损伤中的应用 |
| CN116253782B (zh) * | 2022-09-08 | 2024-06-04 | 浙江大学 | 一种广谱抗菌肽ktr及其应用 |
| CN116375828B (zh) * | 2022-09-08 | 2024-06-04 | 浙江大学 | 一种具有抗菌活性的抗菌肽kta及其应用 |
| FR3141066A1 (fr) * | 2022-10-24 | 2024-04-26 | Basf Beauty Care Solutions France Sas | Nouvelle utilisation d’un peptide pour améliorer la matrice extracellulaire du derme de la peau et/ou des muqueuses |
| CN116491631B (zh) * | 2023-05-26 | 2024-06-25 | 青岛农业大学 | 一种预制菜红烧肉及其制备方法 |
| WO2024259556A1 (en) * | 2023-06-19 | 2024-12-26 | Viage Therapeutics, Inc. | Uses of therapeutic peptides |
| CN117736271B (zh) * | 2023-06-29 | 2024-08-09 | 长沙理工大学 | 一种米渣蛋白源免疫活性肽及其应用 |
| WO2025133189A1 (en) * | 2023-12-20 | 2025-06-26 | Nuritas Limited | Sleep promoting peptides and the use thereof |
| CN117986337B (zh) * | 2024-02-02 | 2024-08-16 | 杭州御寿生物科技有限公司 | 一种提高免疫力的益生菌组合物以及在治疗疾病中的应用 |
| EP4666996A1 (en) * | 2024-06-21 | 2025-12-24 | Quiris Healthcare GmbH & Co. KG | Composition containing peptides of vegetable origin |
| CN120574921A (zh) * | 2025-08-06 | 2025-09-02 | 浙江诺衍生物科技有限公司 | 一种有助于降血糖的大米肽及其应用 |
| CN120590476A (zh) * | 2025-08-06 | 2025-09-05 | 浙江诺衍生物科技有限公司 | 一种有助于降血糖的七肽及其应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4217344A (en) | 1976-06-23 | 1980-08-12 | L'oreal | Compositions containing aqueous dispersions of lipid spheres |
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4186183A (en) | 1978-03-29 | 1980-01-29 | The United States Of America As Represented By The Secretary Of The Army | Liposome carriers in chemotherapy of leishmaniasis |
| US4261975A (en) | 1979-09-19 | 1981-04-14 | Merck & Co., Inc. | Viral liposome particle |
| US4485054A (en) | 1982-10-04 | 1984-11-27 | Lipoderm Pharmaceuticals Limited | Method of encapsulating biologically active materials in multilamellar lipid vesicles (MLV) |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US4946787A (en) | 1985-01-07 | 1990-08-07 | Syntex (U.S.A.) Inc. | N-(ω,(ω-1)-dialkyloxy)- and N-(ω,(ω-1)-dialkenyloxy)-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor |
| US4774085A (en) | 1985-07-09 | 1988-09-27 | 501 Board of Regents, Univ. of Texas | Pharmaceutical administration systems containing a mixture of immunomodulators |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| WO1991017424A1 (en) | 1990-05-03 | 1991-11-14 | Vical, Inc. | Intracellular delivery of biologically active substances by means of self-assembling lipid complexes |
| ES2103366T3 (es) | 1991-03-07 | 1997-09-16 | Novo Nordisk As | Hidrolizado proteico de guisante, metodo para su produccion y su utilizacion. |
| US5516642A (en) | 1992-11-16 | 1996-05-14 | Bristol-Myers Squibb Company | Polypeptides derived from major histocompatibility complex Class I antigen |
| JP2673659B2 (ja) | 1994-02-11 | 1997-11-05 | 株式会社ホーネンコーポレーション | ペプチド |
| US5688489A (en) * | 1995-09-15 | 1997-11-18 | Resolution Pharmaceuticals, Inc. | Non-receptor mediated imaging agents |
| US20040031072A1 (en) | 1999-05-06 | 2004-02-12 | La Rosa Thomas J. | Soy nucleic acid molecules and other molecules associated with transcription plants and uses thereof for plant improvement |
| IT1313572B1 (it) | 1999-07-27 | 2002-09-09 | Enichem Spa | Procedimento per la preparazione di epossidi. |
| US20110131679A2 (en) * | 2000-04-19 | 2011-06-02 | Thomas La Rosa | Rice Nucleic Acid Molecules and Other Molecules Associated with Plants and Uses Thereof for Plant Improvement |
| JP2001335596A (ja) | 2000-05-24 | 2001-12-04 | Kenji Sakamoto | 新規ペプチド及びその医薬用途 |
| AR035860A1 (es) | 2001-04-17 | 2004-07-21 | Femtolink Biotechnologies Llc | Metodos de deteccion por espectrometria de masa y cuantificacion de proteinas blanco especificas en muestras biologicas complejas |
| US7537914B1 (en) | 2002-11-04 | 2009-05-26 | Florida State University Research Foundation, Inc. | Nucleic acid and allergenic polypeptides encoded thereby in cashew nuts (Anacardium occidentale) |
| SE0300795D0 (sv) | 2003-03-24 | 2003-03-24 | Isconova Ab | Composition comprising iscom particles and live micro-organisms |
| AU2004270102B2 (en) | 2003-05-23 | 2009-10-01 | Pestka Biomedical Laboratories, Inc. | Uses of interferons for the treatment of severe acute respiratory syndrome and other viral infections |
| JP4256389B2 (ja) | 2003-11-17 | 2009-04-22 | セダーマ | テトラペプチドとトリペプチドの混合物を含む組成物 |
| US20070053845A1 (en) | 2004-03-02 | 2007-03-08 | Shiladitya Sengupta | Nanocell drug delivery system |
| JP5143729B2 (ja) | 2005-06-29 | 2013-02-13 | ハダジット メディカル リサーチ サービシズ アンド ディベラップメント リミテッド | インスリン抵抗性及び２型糖尿病の予防のためのプロテインキナーゼｃ阻害剤 |
| US8105572B2 (en) | 2007-05-18 | 2012-01-31 | New York University | Method of treating tuberculosis with interferons |
| KR100759495B1 (ko) | 2006-02-17 | 2007-09-18 | 재단법인서울대학교산학협력재단 | 친수성 생리활성 펩타이드와 소수성 물질을 포함한자기조립 나노구조체 |
| CA2649842C (en) | 2006-04-21 | 2015-02-17 | Meiji Seika Kaisha, Ltd. | Composition containing peptide as active ingredient |
| US9034402B2 (en) * | 2007-04-16 | 2015-05-19 | Solae, Llc | Protein hydrolysate compositions having improved sensory characteristics and physical properties |
| DK2840142T3 (en) | 2007-06-06 | 2019-03-18 | Monsanto Technology Llc | Genes and uses for plant improvement |
| NZ583429A (en) * | 2007-08-24 | 2012-08-31 | Mylexa Pty Ltd | Peptides and proteins capable of inhibiting and/or preventing mast cell activation |
| EP2050437A1 (en) | 2007-10-15 | 2009-04-22 | Laboratoires SMB | Improved pharmaceutical dry powder compositions for inhalation. |
| WO2011007612A1 (ja) * | 2009-07-13 | 2011-01-20 | 不二製油株式会社 | 経口性抗炎症剤及び経口性抗炎症ペプチド |
| WO2011122937A1 (en) | 2010-03-29 | 2011-10-06 | N.V. Nutricia | Pea protein peptides with anti helicobacter pylori activity |
| ES2397890B1 (es) | 2011-03-25 | 2014-02-07 | Lipotec, S.A. | Péptidos útiles en el tratamiento y/o cuidado de la piel y/o mucosas y su uso en composiciones cosméticas o farmacéuticas. |
| EP2793605A1 (en) * | 2011-12-21 | 2014-10-29 | Laboratorios Ordesa, S.L | Process for obtaining rice protein hydrolysates useful in the prevention and/or treatment of obesity |
| US9561266B2 (en) | 2012-08-31 | 2017-02-07 | University Of Virginia Patent Foundation | Target peptides for immunotherapy and diagnostics |
| BR112015019748A2 (pt) * | 2013-02-19 | 2017-08-22 | Danone Sa | Peptídeo tendo atividade inibitória da pl e/ou pla2, produto alimentício adequado para o tratamento da obesidade e/ou estresse oxidativo, e, uso de streptococcus thermophilus cncm i-2776 e/ou streptococcus thermophilus cncm i-1630 e/ou lactobacillus paracasei subsp paracasei cncm i-4270 |
| EP3226976A1 (en) | 2014-12-04 | 2017-10-11 | Mary Kay, Inc. | Topical skin care composition comprising trifluoroacetyl tripeptide-2 |
| US20170183386A1 (en) | 2015-07-16 | 2017-06-29 | Nuritas Limited | Peptides, and uses thereof |
-
2016
- 2016-07-18 BR BR112018000660-2A patent/BR112018000660A2/pt not_active Application Discontinuation
- 2016-07-18 CN CN201680051932.6A patent/CN108348568B/zh active Active
- 2016-07-18 MX MX2018000697A patent/MX377692B/es active IP Right Grant
- 2016-07-18 KR KR1020217030710A patent/KR102576571B1/ko active Active
- 2016-07-18 KR KR1020237030244A patent/KR20230132623A/ko not_active Withdrawn
- 2016-07-18 DK DK16751491.8T patent/DK3322430T3/da active
- 2016-07-18 JP JP2018521713A patent/JP2018523703A/ja active Pending
- 2016-07-18 EP EP21178569.6A patent/EP3954700A1/en not_active Withdrawn
- 2016-07-18 EP EP20165063.7A patent/EP3747425A1/en not_active Withdrawn
- 2016-07-18 US US15/744,304 patent/US10463591B2/en active Active
- 2016-07-18 AU AU2016293129A patent/AU2016293129B2/en active Active
- 2016-07-18 WO PCT/EP2016/067090 patent/WO2017009484A1/en not_active Ceased
- 2016-07-18 CN CN202111590603.8A patent/CN114835784B/zh active Active
- 2016-07-18 CA CA2992378A patent/CA2992378A1/en active Pending
- 2016-07-18 ES ES16751491T patent/ES2806989T3/es active Active
- 2016-07-18 EP EP16751491.8A patent/EP3322430B1/en active Active
- 2016-07-18 KR KR1020187004160A patent/KR102307260B1/ko active Active
-
2018
- 2018-01-16 MX MX2020010806A patent/MX2020010806A/es unknown
-
2019
- 2019-09-12 US US16/569,159 patent/US11253456B2/en active Active
-
2021
- 2021-04-21 AU AU2021202423A patent/AU2021202423A1/en not_active Abandoned
- 2021-10-22 JP JP2021173218A patent/JP7288026B2/ja active Active
-
2022
- 2022-01-13 US US17/574,865 patent/US11779531B2/en active Active
-
2023
- 2023-05-25 JP JP2023086030A patent/JP7739355B2/ja active Active
- 2023-08-17 US US18/451,560 patent/US20240238184A1/en active Pending
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