BR112017004828B1 - Injeção supracoroidal motorizada de agente terapêutico - Google Patents
Injeção supracoroidal motorizada de agente terapêutico Download PDFInfo
- Publication number
- BR112017004828B1 BR112017004828B1 BR112017004828-0A BR112017004828A BR112017004828B1 BR 112017004828 B1 BR112017004828 B1 BR 112017004828B1 BR 112017004828 A BR112017004828 A BR 112017004828A BR 112017004828 B1 BR112017004828 B1 BR 112017004828B1
- Authority
- BR
- Brazil
- Prior art keywords
- needle
- cannula
- eye
- approximately
- therapeutic agent
- Prior art date
Links
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1585—Needle inserters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
- A61M2005/1586—Holding accessories for holding infusion needles on the body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
Landscapes
- Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Prostheses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462049118P | 2014-09-11 | 2014-09-11 | |
| US62/049,118 | 2014-09-11 | ||
| US14/840,622 | 2015-08-31 | ||
| US14/840,622 US10064752B2 (en) | 2014-09-11 | 2015-08-31 | Motorized suprachoroidal injection of therapeutic agent |
| PCT/US2015/049430 WO2016040635A1 (en) | 2014-09-11 | 2015-09-10 | Motorized suprachoroidal injection of therapeutic agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112017004828A2 BR112017004828A2 (pt) | 2017-12-12 |
| BR112017004828B1 true BR112017004828B1 (pt) | 2021-12-14 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112017004828-0A BR112017004828B1 (pt) | 2014-09-11 | 2015-09-10 | Injeção supracoroidal motorizada de agente terapêutico |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10064752B2 (enExample) |
| EP (1) | EP3191033B1 (enExample) |
| JP (1) | JP6541162B2 (enExample) |
| KR (1) | KR20170063697A (enExample) |
| CN (1) | CN107249523B (enExample) |
| AU (1) | AU2015315044A1 (enExample) |
| BR (1) | BR112017004828B1 (enExample) |
| CA (1) | CA2960649A1 (enExample) |
| MX (1) | MX2017003260A (enExample) |
| PH (1) | PH12017500443A1 (enExample) |
| RU (1) | RU2017112036A (enExample) |
| SG (1) | SG11201701968QA (enExample) |
| WO (1) | WO2016040635A1 (enExample) |
| ZA (1) | ZA201702514B (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106687078B (zh) | 2014-02-12 | 2019-10-25 | 轨道生物医学有限公司 | 用于治疗剂的脉络膜上施用的方法和设备 |
| US10064752B2 (en) | 2014-09-11 | 2018-09-04 | Orbit Biomedical Limited | Motorized suprachoroidal injection of therapeutic agent |
| US10258502B2 (en) | 2014-09-18 | 2019-04-16 | Orbit Biomedical Limited | Therapeutic agent delivery device |
| WO2016042162A1 (en) | 2014-09-19 | 2016-03-24 | Medterials, Inc. | Ophthalmic delivery device |
| WO2017046358A1 (en) | 2015-09-17 | 2017-03-23 | Medterials, Inc. | Ophthalmic injection device |
| US10478553B2 (en) | 2016-03-09 | 2019-11-19 | Orbit Biomedical Limited | Apparatus for subretinal administration of therapeutic agent via a curved needle |
| AU2017235845B2 (en) | 2016-03-16 | 2022-06-09 | Oxular Limited | Ophthalmic delivery device and ophthalmic drug compositions |
| MA44873A (fr) | 2016-04-15 | 2019-03-13 | Univ Pennsylvania | Composition pour le traitement de la dégénérescence maculaire liée a l'âge exsudative |
| US10646374B2 (en) | 2016-06-17 | 2020-05-12 | Orbit Biomedical Limited | Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent |
| US10806629B2 (en) | 2016-06-17 | 2020-10-20 | Gyroscope Therapeutics Limited | Injection device for subretinal delivery of therapeutic agent |
| US11000410B2 (en) | 2016-06-17 | 2021-05-11 | Gyroscope Therapeutics Limited | Guide apparatus for tangential entry into suprachoroidal space |
| WO2018057871A1 (en) * | 2016-09-23 | 2018-03-29 | The Regents Of The University Of California | Surgical device for ab-externo sub-retinal fluid drainage |
| US11273072B2 (en) | 2017-01-13 | 2022-03-15 | Gyroscope Therapeutics Limited | Suprachoroidal injection device |
| US11076984B2 (en) | 2017-03-13 | 2021-08-03 | Gyroscope Therapeutics Limited | Method of performing subretinal drainage and agent delivery |
| US11033427B2 (en) | 2017-04-13 | 2021-06-15 | Alcon Inc. | Vitreoretinal instruments for fluid aspiration |
| EP3621685B1 (en) * | 2017-05-08 | 2025-11-26 | Medtronic MiniMed, Inc. | Flexible tubing, cannula and insertion needle |
| EP3681471B1 (en) * | 2017-09-15 | 2025-03-05 | Oxular Limited | Ophthalmic delivery device |
| KR20200060456A (ko) * | 2017-09-27 | 2020-05-29 | 리젠엑스바이오 인크. | 완전-인간 번역후 변형된 항-VEGF Fab를 이용한 안구 질환의 치료 |
| CN109224190B (zh) * | 2018-07-20 | 2020-11-03 | 陈红雨 | 一种用于患儿头部注射的固定器 |
| CN109200384A (zh) * | 2018-10-31 | 2019-01-15 | 中国人民解放军陆军特色医学中心 | 一种留置针 |
| US11759355B1 (en) | 2019-02-26 | 2023-09-19 | Gyroscope Therapeutics Limited | Method of delivering leading blebs and agent to subretinal space |
| CN113966236A (zh) * | 2019-04-03 | 2022-01-21 | 再生生物股份有限公司 | 眼睛病状的基因疗法 |
| US11690974B2 (en) | 2019-04-25 | 2023-07-04 | Warsaw Orthopedic, Inc. | Methods and devices for delivering therapeutic materials to the intervertebral disc |
| US12083329B2 (en) * | 2019-08-22 | 2024-09-10 | Boston Scientific Scimed, Inc. | Systems and methods for controlling needle penetration |
| WO2021041373A1 (en) | 2019-08-26 | 2021-03-04 | Regenxbio Inc. | Treatment of diabetic retinopathy with fully-human post-translationally modified anti-vegf fab |
| CN114728049A (zh) | 2019-10-07 | 2022-07-08 | 再生生物股份有限公司 | 腺相关病毒载体药物组合物和方法 |
| US11771834B2 (en) | 2019-10-11 | 2023-10-03 | Gyroscope Therapeutics Limited | Dose clip assembly for syringe |
| JP2023544803A (ja) | 2020-10-07 | 2023-10-25 | レジェンクスバイオ インコーポレーテッド | Ｃｌｎ２疾患の眼症状に対する遺伝子療法 |
| CA3208905A1 (en) | 2021-02-12 | 2022-08-18 | Boehringer Ingelheim International Gmbh | Complement c3 antigen binding proteins |
| AU2022420788A1 (en) | 2021-12-22 | 2024-05-16 | Boehringer Ingelheim International Gmbh | Anti-c3 antibodies and antigen-binding fragments thereof and their uses for treating eye or ocular diseases |
| US20250249127A1 (en) | 2022-04-14 | 2025-08-07 | Regenxbio Inc. | Gene therapy for treating an ocular disease |
| JP2025527930A (ja) | 2022-09-06 | 2025-08-22 | ジェネンテック， インコーポレイテッド | 二重湾曲針を介した治療剤の網膜下投与のための装置 |
| WO2024059794A1 (en) * | 2022-09-16 | 2024-03-21 | Cvrx, Inc. | System, devices, and methods for guidewire delivery |
| IL319873A (en) | 2022-09-30 | 2025-05-01 | Regenxbio Inc | Treatment of eye diseases with recombinant viral vectors containing anti-VEGF FAB |
| CN120513071A (zh) | 2023-01-13 | 2025-08-19 | 基因泰克公司 | 用于注射器的剂量对接座 |
| WO2025072590A1 (en) | 2023-09-29 | 2025-04-03 | Genentech, Inc. | Ocular cannula guide, applicator, and marking instrument |
| WO2025160409A1 (en) | 2024-01-26 | 2025-07-31 | Flagship Pioneering Innovations V, Inc. | Viral vectors for modulating vegf function |
| WO2025207699A1 (en) | 2024-03-27 | 2025-10-02 | Genentech, Inc. | Torque ring for subretinal injection device |
| WO2025217214A2 (en) | 2024-04-08 | 2025-10-16 | Regenxbio Inc. | Recombinant adeno-associated viruses and uses thereof |
| WO2025217230A1 (en) | 2024-04-08 | 2025-10-16 | Regenxbio Inc. | Vectorized anti-complement antibodies and complement agents and administration thereof |
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| CN2045634U (zh) * | 1989-01-11 | 1989-10-11 | 晁三万 | 多功能微调眼科手术刀 |
| US6309374B1 (en) | 1998-08-03 | 2001-10-30 | Insite Vision Incorporated | Injection apparatus and method of using same |
| CN2409937Y (zh) * | 2000-02-03 | 2000-12-13 | 李根林 | 视网膜移植器 |
| US20020087128A1 (en) | 2000-08-31 | 2002-07-04 | Mpnb Ltd. | Microsurgical injection and/or distending instruments and surgical method and apparatus utilizing same |
| US20040199130A1 (en) | 2003-04-03 | 2004-10-07 | Chornenky Victor I. | Apparatus and method for treatment of macular degeneration |
| CA2530421C (en) | 2003-06-27 | 2015-04-21 | Ethicon, Incorporated | Repair and regeneration of ocular tissue using postpartum-derived cells |
| WO2008036304A2 (en) * | 2006-09-19 | 2008-03-27 | The Trustees Of Columbia University In The City Of New York | Systems, devices, and methods for surgery on a hollow anatomically suspended organ |
| SG193448A1 (en) * | 2011-03-16 | 2013-10-30 | Becton Dickinson Co | Multiple use disposable injection pen |
| US9539384B2 (en) * | 2012-09-28 | 2017-01-10 | Animas Corporation | Telescoping piston drive for medical infusion device |
| CN106687078B (zh) | 2014-02-12 | 2019-10-25 | 轨道生物医学有限公司 | 用于治疗剂的脉络膜上施用的方法和设备 |
| US10064752B2 (en) | 2014-09-11 | 2018-09-04 | Orbit Biomedical Limited | Motorized suprachoroidal injection of therapeutic agent |
-
2015
- 2015-08-31 US US14/840,622 patent/US10064752B2/en active Active
- 2015-09-10 AU AU2015315044A patent/AU2015315044A1/en not_active Abandoned
- 2015-09-10 RU RU2017112036A patent/RU2017112036A/ru unknown
- 2015-09-10 CN CN201580061178.XA patent/CN107249523B/zh active Active
- 2015-09-10 EP EP15775026.6A patent/EP3191033B1/en active Active
- 2015-09-10 SG SG11201701968QA patent/SG11201701968QA/en unknown
- 2015-09-10 KR KR1020177009663A patent/KR20170063697A/ko not_active Withdrawn
- 2015-09-10 JP JP2017513696A patent/JP6541162B2/ja active Active
- 2015-09-10 MX MX2017003260A patent/MX2017003260A/es unknown
- 2015-09-10 CA CA2960649A patent/CA2960649A1/en not_active Abandoned
- 2015-09-10 WO PCT/US2015/049430 patent/WO2016040635A1/en not_active Ceased
- 2015-09-10 BR BR112017004828-0A patent/BR112017004828B1/pt active IP Right Grant
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2017
- 2017-03-09 PH PH12017500443A patent/PH12017500443A1/en unknown
- 2017-04-10 ZA ZA2017/02514A patent/ZA201702514B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN107249523A (zh) | 2017-10-13 |
| AU2015315044A1 (en) | 2017-03-30 |
| EP3191033A1 (en) | 2017-07-19 |
| CN107249523B (zh) | 2020-09-22 |
| BR112017004828A2 (pt) | 2017-12-12 |
| PH12017500443A1 (en) | 2017-07-31 |
| KR20170063697A (ko) | 2017-06-08 |
| JP2017526478A (ja) | 2017-09-14 |
| WO2016040635A1 (en) | 2016-03-17 |
| RU2017112036A (ru) | 2018-10-11 |
| US10064752B2 (en) | 2018-09-04 |
| MX2017003260A (es) | 2018-02-12 |
| SG11201701968QA (en) | 2017-04-27 |
| ZA201702514B (en) | 2019-07-31 |
| CA2960649A1 (en) | 2016-03-17 |
| EP3191033B1 (en) | 2019-11-06 |
| JP6541162B2 (ja) | 2019-07-10 |
| US20160074217A1 (en) | 2016-03-17 |
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