CN107249523B - 治疗剂的电动脉络膜上注射 - Google Patents

治疗剂的电动脉络膜上注射 Download PDF

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Publication number
CN107249523B
CN107249523B CN201580061178.XA CN201580061178A CN107249523B CN 107249523 B CN107249523 B CN 107249523B CN 201580061178 A CN201580061178 A CN 201580061178A CN 107249523 B CN107249523 B CN 107249523B
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China
Prior art keywords
needle
cannula
eye
actuation
actuation assembly
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CN201580061178.XA
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English (en)
Chinese (zh)
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CN107249523A (zh
Inventor
D·W·普莱斯
I·J·科汉
B·J·奥伯基尔彻
S·索科罕沃尔
D·J·亚赛瓦克
M·布鲁威尔
L·R·索菲
M·T·卡特
G·W·约翰森
M·拉梅阿尼费尔德
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Genentech Inc
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Orbit Biomedical Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3287—Accessories for bringing the needle into the body; Automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0026—Ophthalmic product dispenser attachments to facilitate positioning near the eye
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1585—Needle inserters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/158—Needles for infusions; Accessories therefor, e.g. for inserting infusion needles, or for holding them on the body
    • A61M2005/1586—Holding accessories for holding infusion needles on the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Prostheses (AREA)
CN201580061178.XA 2014-09-11 2015-09-10 治疗剂的电动脉络膜上注射 Active CN107249523B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462049118P 2014-09-11 2014-09-11
US62/049,118 2014-09-11
US14/840,622 2015-08-31
US14/840,622 US10064752B2 (en) 2014-09-11 2015-08-31 Motorized suprachoroidal injection of therapeutic agent
PCT/US2015/049430 WO2016040635A1 (en) 2014-09-11 2015-09-10 Motorized suprachoroidal injection of therapeutic agent

Publications (2)

Publication Number Publication Date
CN107249523A CN107249523A (zh) 2017-10-13
CN107249523B true CN107249523B (zh) 2020-09-22

Family

ID=55453677

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201580061178.XA Active CN107249523B (zh) 2014-09-11 2015-09-10 治疗剂的电动脉络膜上注射

Country Status (14)

Country Link
US (1) US10064752B2 (enExample)
EP (1) EP3191033B1 (enExample)
JP (1) JP6541162B2 (enExample)
KR (1) KR20170063697A (enExample)
CN (1) CN107249523B (enExample)
AU (1) AU2015315044A1 (enExample)
BR (1) BR112017004828B1 (enExample)
CA (1) CA2960649A1 (enExample)
MX (1) MX2017003260A (enExample)
PH (1) PH12017500443A1 (enExample)
RU (1) RU2017112036A (enExample)
SG (1) SG11201701968QA (enExample)
WO (1) WO2016040635A1 (enExample)
ZA (1) ZA201702514B (enExample)

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EP4555981A3 (en) 2014-02-12 2025-08-06 Genentech, Inc. Method and apparatus for suprachoroidal administration of therapeutic agent
US10064752B2 (en) 2014-09-11 2018-09-04 Orbit Biomedical Limited Motorized suprachoroidal injection of therapeutic agent
US10258502B2 (en) 2014-09-18 2019-04-16 Orbit Biomedical Limited Therapeutic agent delivery device
CN107249522B (zh) 2014-09-19 2021-04-20 奥叙拉尔有限公司 眼科递送装置
JP6920002B2 (ja) 2015-09-17 2021-08-18 オクラー リミテッド 眼科用注射装置
US10478553B2 (en) 2016-03-09 2019-11-19 Orbit Biomedical Limited Apparatus for subretinal administration of therapeutic agent via a curved needle
PL3429519T3 (pl) 2016-03-16 2023-10-30 Oxular Limited Urządzenie do dostarczania oftalmicznego
IL322403A (en) 2016-04-15 2025-09-01 Univ Pennsylvania Preparations for the treatment of wet age-related macular degeneration
US10646374B2 (en) 2016-06-17 2020-05-12 Orbit Biomedical Limited Apparatus and method to form entry bleb for subretinal delivery of therapeutic agent
US11000410B2 (en) 2016-06-17 2021-05-11 Gyroscope Therapeutics Limited Guide apparatus for tangential entry into suprachoroidal space
US10806629B2 (en) 2016-06-17 2020-10-20 Gyroscope Therapeutics Limited Injection device for subretinal delivery of therapeutic agent
WO2018057871A1 (en) * 2016-09-23 2018-03-29 The Regents Of The University Of California Surgical device for ab-externo sub-retinal fluid drainage
US11273072B2 (en) 2017-01-13 2022-03-15 Gyroscope Therapeutics Limited Suprachoroidal injection device
US11076984B2 (en) 2017-03-13 2021-08-03 Gyroscope Therapeutics Limited Method of performing subretinal drainage and agent delivery
US11033427B2 (en) 2017-04-13 2021-06-15 Alcon Inc. Vitreoretinal instruments for fluid aspiration
US11027061B2 (en) 2017-05-08 2021-06-08 Medtronic Minimed, Inc. Flexible cannula insertion device, system and process
JP7344197B2 (ja) * 2017-09-15 2023-09-13 オクラー リミテッド 眼科用送達装置
JP7685833B2 (ja) * 2017-09-27 2025-05-30 レジェンクスバイオ インコーポレーテッド 翻訳後修飾された完全ヒト抗ＶＥＧＦ Ｆａｂによる眼疾患の治療
US12558434B2 (en) 2018-02-20 2026-02-24 The Trustees Of The University Of Pennsylvania Compositions for treatment of wet age-related macular degeneration
CN109224190B (zh) * 2018-07-20 2020-11-03 陈红雨 一种用于患儿头部注射的固定器
CN109200384A (zh) * 2018-10-31 2019-01-15 中国人民解放军陆军特色医学中心 一种留置针
US11759355B1 (en) 2019-02-26 2023-09-19 Gyroscope Therapeutics Limited Method of delivering leading blebs and agent to subretinal space
EP3946467A1 (en) 2019-04-03 2022-02-09 REGENXBIO Inc. Gene therapy for eye pathologies
US11690974B2 (en) 2019-04-25 2023-07-04 Warsaw Orthopedic, Inc. Methods and devices for delivering therapeutic materials to the intervertebral disc
WO2021034493A1 (en) * 2019-08-22 2021-02-25 Boston Scientific Scimed, Inc. Systems and methods for controlling needle penetration
CN114502197A (zh) 2019-08-26 2022-05-13 再生生物股份有限公司 用全人经翻译后修饰的抗VEGF Fab治疗糖尿病性视网膜病变
US20240108669A1 (en) 2019-10-07 2024-04-04 Regenxbio Inc. Adeno-associated virus vector pharmaceutical composition and methods
WO2021069968A1 (en) 2019-10-11 2021-04-15 Gyroscope Therapeutics Limited Dose clip assembly for syringe
KR20230083287A (ko) 2020-10-07 2023-06-09 리젠엑스바이오 인크. Cln2 질환의 안구 징후에 대한 유전자 요법
TW202246319A (zh) 2021-02-12 2022-12-01 德商百靈佳殷格翰國際股份有限公司 補體c3抗原結合蛋白
AU2022420788A1 (en) 2021-12-22 2024-05-16 Boehringer Ingelheim International Gmbh Anti-c3 antibodies and antigen-binding fragments thereof and their uses for treating eye or ocular diseases
EP4507741A1 (en) 2022-04-14 2025-02-19 RegenxBio Inc. Gene therapy for treating an ocular disease
JP2025527930A (ja) 2022-09-06 2025-08-22 ジェネンテック， インコーポレイテッド 二重湾曲針を介した治療剤の網膜下投与のための装置
WO2024059794A1 (en) * 2022-09-16 2024-03-21 Cvrx, Inc. System, devices, and methods for guidewire delivery
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JP2026500975A (ja) 2023-01-13 2026-01-09 ジェネンテック， インコーポレイテッド シリンジのための投与ドック
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WO2025207699A1 (en) 2024-03-27 2025-10-02 Genentech, Inc. Torque ring for subretinal injection device
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CN2045634U (zh) * 1989-01-11 1989-10-11 晁三万 多功能微调眼科手术刀
CN2409937Y (zh) * 2000-02-03 2000-12-13 李根林 视网膜移植器
US6309374B1 (en) * 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
WO2002017986A2 (en) * 2000-08-31 2002-03-07 Mpnb Ltd. Microsurgical injection and/or distending instrument

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JP2010504151A (ja) * 2006-09-19 2010-02-12 ザ トラスティーズ オブ コロンビア ユニヴァーシティ イン ザ シティ オブ ニューヨーク 中空の解剖学的に懸吊された器官の手術のためのシステム、装置、及び方法
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CN2045634U (zh) * 1989-01-11 1989-10-11 晁三万 多功能微调眼科手术刀
US6309374B1 (en) * 1998-08-03 2001-10-30 Insite Vision Incorporated Injection apparatus and method of using same
CN2409937Y (zh) * 2000-02-03 2000-12-13 李根林 视网膜移植器
WO2002017986A2 (en) * 2000-08-31 2002-03-07 Mpnb Ltd. Microsurgical injection and/or distending instrument

Also Published As

Publication number Publication date
SG11201701968QA (en) 2017-04-27
CA2960649A1 (en) 2016-03-17
PH12017500443A1 (en) 2017-07-31
RU2017112036A (ru) 2018-10-11
WO2016040635A1 (en) 2016-03-17
MX2017003260A (es) 2018-02-12
ZA201702514B (en) 2019-07-31
US10064752B2 (en) 2018-09-04
EP3191033A1 (en) 2017-07-19
JP2017526478A (ja) 2017-09-14
JP6541162B2 (ja) 2019-07-10
BR112017004828A2 (pt) 2017-12-12
CN107249523A (zh) 2017-10-13
AU2015315044A1 (en) 2017-03-30
US20160074217A1 (en) 2016-03-17
BR112017004828B1 (pt) 2021-12-14
KR20170063697A (ko) 2017-06-08
EP3191033B1 (en) 2019-11-06

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