BR112017000270A2 - método para vedar substâncias e método de detecção de molécula alvo - Google Patents
método para vedar substâncias e método de detecção de molécula alvoInfo
- Publication number
- BR112017000270A2 BR112017000270A2 BR112017000270-1A BR112017000270A BR112017000270A2 BR 112017000270 A2 BR112017000270 A2 BR 112017000270A2 BR 112017000270 A BR112017000270 A BR 112017000270A BR 112017000270 A2 BR112017000270 A2 BR 112017000270A2
- Authority
- BR
- Brazil
- Prior art keywords
- detect
- target molecule
- enclosure method
- substance enclosure
- substance
- Prior art date
Links
- 239000000126 substance Substances 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4044—Concentrating samples by chemical techniques; Digestion; Chemical decomposition
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54393—Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/04—Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/24—Methods of sampling, or inoculating or spreading a sample; Methods of physically isolating an intact microorganisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- G01N15/1433—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N37/00—Details not covered by any other group of this subclass
-
- G01N15/01—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
- G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2014-140700 | 2014-07-08 | ||
JP2014140700 | 2014-07-08 | ||
PCT/JP2015/003310 WO2016006208A1 (ja) | 2014-07-08 | 2015-07-01 | 物質封入方法及びターゲット分子を検出する方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112017000270A2 true BR112017000270A2 (pt) | 2018-06-26 |
BR112017000270B1 BR112017000270B1 (pt) | 2021-03-23 |
Family
ID=55063860
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112017000270-1A BR112017000270B1 (pt) | 2014-07-08 | 2015-07-01 | Método para armazenar substâncias e método de detecção de molécula alvo |
Country Status (12)
Country | Link |
---|---|
US (1) | US10451619B2 (pt) |
EP (1) | EP3168624B1 (pt) |
JP (1) | JP6611714B2 (pt) |
KR (1) | KR102437408B1 (pt) |
CN (1) | CN106662599B (pt) |
AU (1) | AU2015286488B2 (pt) |
BR (1) | BR112017000270B1 (pt) |
CA (1) | CA2953666C (pt) |
ES (1) | ES2831360T3 (pt) |
RU (1) | RU2691694C2 (pt) |
SG (2) | SG10201811714UA (pt) |
WO (1) | WO2016006208A1 (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7009993B2 (ja) | 2015-09-08 | 2022-01-26 | 凸版印刷株式会社 | 生体物質検出方法および生体物質導入方法 |
WO2018043733A1 (ja) * | 2016-09-05 | 2018-03-08 | 国立研究開発法人科学技術振興機構 | 病原性微生物検出のための方法及びキット |
JP7016136B2 (ja) | 2016-09-05 | 2022-02-04 | 国立研究開発法人科学技術振興機構 | 病原性微生物検出のための方法及びキット |
US10324041B2 (en) | 2016-12-21 | 2019-06-18 | Abbott Japan Co., Ltd. | Optical imaging system using lateral illumination for digital assays |
US11047854B2 (en) | 2017-02-06 | 2021-06-29 | Abbott Japan Llc | Methods for reducing noise in signal-generating digital assays |
JP7125763B2 (ja) * | 2017-03-29 | 2022-08-25 | 国立研究開発法人科学技術振興機構 | 微小物質封入方法及び微小物質検出方法並びに微小物質検出用デバイス |
JP7212940B2 (ja) * | 2017-03-29 | 2023-01-26 | 国立研究開発法人科学技術振興機構 | 微小物質検出方法及び微小物質検出用デバイス |
CN110769925A (zh) * | 2017-03-29 | 2020-02-07 | 康奈尔大学 | 使用组合的核酸酶、连结酶、聚合酶以及测序反应测定核酸序列、表达、拷贝数或甲基化变化的装置、方法以及系统 |
WO2018185871A1 (ja) | 2017-04-05 | 2018-10-11 | 株式会社日立ハイテクノロジーズ | 核酸増幅方法および核酸解析用装置 |
WO2019168200A1 (ja) * | 2018-03-02 | 2019-09-06 | 国立研究開発法人科学技術振興機構 | 酵素反応生成物の検出方法 |
JP7219919B2 (ja) * | 2019-05-20 | 2023-02-09 | 日本航空電子工業株式会社 | 触媒反応生成物の電気化学的測定方法及びトランスデューサ |
CN113825842A (zh) * | 2019-05-21 | 2021-12-21 | 凸版印刷株式会社 | 靶分子的检测方法 |
JP7201178B2 (ja) * | 2019-06-13 | 2023-01-10 | 日本航空電子工業株式会社 | 触媒反応生成物の電気化学的測定方法、電気化学測定装置及びトランスデューサ |
JPWO2022202218A1 (pt) | 2021-03-26 | 2022-09-29 | ||
WO2022202217A1 (ja) | 2021-03-26 | 2022-09-29 | 国立研究開発法人産業技術総合研究所 | ウエルアレイを用いたウイルス検出方法、ウエルアレイ及び検出装置 |
Family Cites Families (24)
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US7214540B2 (en) | 1999-04-06 | 2007-05-08 | Uab Research Foundation | Method for screening crystallization conditions in solution crystal growth |
US20020039728A1 (en) | 2000-02-10 | 2002-04-04 | Robert Kain | Alternative substrates and formats for bead-based array of arrays |
WO2004074818A2 (en) * | 2002-12-20 | 2004-09-02 | Biotrove, Inc. | Assay apparatus and method using microfluidic arrays |
JP3727026B2 (ja) | 2003-04-10 | 2005-12-14 | 博行 野地 | 一分子酵素活性検出に用いられるマイクロチャンバと1000fL以下の液滴を調製する方法 |
BRPI0414004A (pt) | 2003-08-27 | 2006-10-24 | Harvard College | controle eletrÈnico de espécies fluìdicas |
JP4547301B2 (ja) | 2005-05-13 | 2010-09-22 | 株式会社日立ハイテクノロジーズ | 液体搬送デバイス及び分析システム |
WO2006127451A2 (en) | 2005-05-21 | 2006-11-30 | Core-Microsolutions, Inc. | Mitigation of biomolecular adsorption with hydrophilic polymer additives |
JP2007017253A (ja) | 2005-07-07 | 2007-01-25 | Olympus Corp | 容器および粒子 |
CA2680532C (en) | 2006-04-18 | 2017-03-21 | Advanced Liquid Logic, Inc. | Droplet-based pyrosequencing |
JP4866208B2 (ja) | 2006-10-31 | 2012-02-01 | 株式会社島津製作所 | マイクロ反応装置 |
US8440392B2 (en) | 2007-03-22 | 2013-05-14 | Advanced Liquid Logic Inc. | Method of conducting a droplet based enzymatic assay |
JP5009125B2 (ja) | 2007-10-26 | 2012-08-22 | 日立マクセル株式会社 | 機能性粒子を利用したマイクロデバイスおよびそれを用いた処理方法 |
JP2009162549A (ja) | 2007-12-28 | 2009-07-23 | Nec Corp | 電気泳動チップ |
US20110065086A1 (en) | 2008-02-21 | 2011-03-17 | Otc Biotechnologies, Llc | Methods of producing homogeneous plastic-adherent aptamer-magnetic bead-fluorophore and other sandwich assays |
JP5390540B2 (ja) | 2008-02-29 | 2014-01-15 | ノースウエスタン ユニバーシティ | 生物反応促進用バリア |
EP4047367A1 (en) | 2008-07-18 | 2022-08-24 | Bio-Rad Laboratories, Inc. | Method for detecting target analytes with droplet libraries |
JP5030897B2 (ja) * | 2008-08-28 | 2012-09-19 | メタウォーター株式会社 | 微生物計測方法 |
EP2517025B1 (en) * | 2009-12-23 | 2019-11-27 | Bio-Rad Laboratories, Inc. | Methods for reducing the exchange of molecules between droplets |
US8236574B2 (en) * | 2010-03-01 | 2012-08-07 | Quanterix Corporation | Ultra-sensitive detection of molecules or particles using beads or other capture objects |
WO2011109379A1 (en) | 2010-03-01 | 2011-09-09 | Quanterix Corporation | Methods and systems for extending dynamic range in assays for the detection of molecules or particles |
CN101947124B (zh) | 2010-06-25 | 2012-07-04 | 博奥生物有限公司 | 一种集成式微流控芯片装置及其使用方法 |
EP2622103B2 (en) * | 2010-09-30 | 2022-11-16 | Bio-Rad Laboratories, Inc. | Sandwich assays in droplets |
RU2548619C1 (ru) * | 2011-03-08 | 2015-04-20 | Японское Агентство По Науке И Технике | Способ герметизации гранул, способ обнаружения молекулы-мишени, матрица, набор и устройство для обнаружения молекулы-мишени |
EP2891886B1 (en) | 2012-08-31 | 2018-10-10 | The University of Tokyo | Detector and detection method |
-
2015
- 2015-07-01 WO PCT/JP2015/003310 patent/WO2016006208A1/ja active Application Filing
- 2015-07-01 SG SG10201811714UA patent/SG10201811714UA/en unknown
- 2015-07-01 US US15/321,312 patent/US10451619B2/en active Active
- 2015-07-01 CA CA2953666A patent/CA2953666C/en active Active
- 2015-07-01 EP EP15819235.1A patent/EP3168624B1/en active Active
- 2015-07-01 KR KR1020167034481A patent/KR102437408B1/ko active IP Right Grant
- 2015-07-01 SG SG11201700133SA patent/SG11201700133SA/en unknown
- 2015-07-01 BR BR112017000270-1A patent/BR112017000270B1/pt active IP Right Grant
- 2015-07-01 JP JP2016532426A patent/JP6611714B2/ja active Active
- 2015-07-01 RU RU2017103947A patent/RU2691694C2/ru active
- 2015-07-01 CN CN201580036253.7A patent/CN106662599B/zh active Active
- 2015-07-01 ES ES15819235T patent/ES2831360T3/es active Active
- 2015-07-01 AU AU2015286488A patent/AU2015286488B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP3168624B1 (en) | 2020-08-26 |
JPWO2016006208A1 (ja) | 2017-04-27 |
EP3168624A4 (en) | 2018-01-10 |
RU2691694C2 (ru) | 2019-06-17 |
KR20170027716A (ko) | 2017-03-10 |
US20170176430A1 (en) | 2017-06-22 |
CN106662599A (zh) | 2017-05-10 |
KR102437408B1 (ko) | 2022-08-29 |
US10451619B2 (en) | 2019-10-22 |
CA2953666A1 (en) | 2016-01-14 |
CN106662599B (zh) | 2020-04-28 |
SG10201811714UA (en) | 2019-01-30 |
EP3168624A1 (en) | 2017-05-17 |
JP6611714B2 (ja) | 2019-11-27 |
AU2015286488A1 (en) | 2017-02-16 |
AU2015286488B2 (en) | 2020-07-16 |
ES2831360T3 (es) | 2021-06-08 |
BR112017000270B1 (pt) | 2021-03-23 |
WO2016006208A1 (ja) | 2016-01-14 |
SG11201700133SA (en) | 2017-03-30 |
CA2953666C (en) | 2022-08-16 |
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Legal Events
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 01/07/2015, OBSERVADAS AS CONDICOES LEGAIS. |