BR112016030577A2 - vacinas contra o vírus da gripe e usos das mesmas - Google Patents
vacinas contra o vírus da gripe e usos das mesmasInfo
- Publication number
- BR112016030577A2 BR112016030577A2 BR112016030577A BR112016030577A BR112016030577A2 BR 112016030577 A2 BR112016030577 A2 BR 112016030577A2 BR 112016030577 A BR112016030577 A BR 112016030577A BR 112016030577 A BR112016030577 A BR 112016030577A BR 112016030577 A2 BR112016030577 A2 BR 112016030577A2
- Authority
- BR
- Brazil
- Prior art keywords
- influenza vaccines
- methods
- same
- stem domain
- domain polypeptides
- Prior art date
Links
- 229960003971 influenza vaccine Drugs 0.000 title 1
- 101710154606 Hemagglutinin Proteins 0.000 abstract 2
- 101710093908 Outer capsid protein VP4 Proteins 0.000 abstract 2
- 101710135467 Outer capsid protein sigma-1 Proteins 0.000 abstract 2
- 101710176177 Protein A56 Proteins 0.000 abstract 2
- 239000000185 hemagglutinin Substances 0.000 abstract 2
- 206010022000 influenza Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 238000001514 detection method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/08—RNA viruses
- C07K14/11—Orthomyxoviridae, e.g. influenza virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16123—Virus like particles [VLP]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
são fornecidos aqui polipeptídeos multiméricos do domínio de haste da hemaglutinina da gripe, métodos para proporcionar poli-peptídeos do domínio de haste da hemaglutinina, composições compreendendo os mesmos, vacinas compreendendo os mesmos e métodos de seu uso, em particular na detecção, prevenção e/ou tratamento da gripe.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14176459 | 2014-07-10 | ||
US201462062754P | 2014-10-10 | 2014-10-10 | |
EP14195143 | 2014-11-27 | ||
EP15155761 | 2015-02-19 | ||
PCT/EP2015/065663 WO2016005482A1 (en) | 2014-07-10 | 2015-07-09 | Influenza virus vaccines and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016030577A2 true BR112016030577A2 (pt) | 2017-10-31 |
BR112016030577A8 BR112016030577A8 (pt) | 2021-07-20 |
Family
ID=55063616
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016030577A BR112016030577A8 (pt) | 2014-07-10 | 2015-07-09 | polipeptídeos multiméricos do domínio de haste da hemaglutinina da gripe, molécula de ácido nucleico, vetor, composição e usos destes |
Country Status (17)
Country | Link |
---|---|
US (1) | US10117925B2 (pt) |
EP (1) | EP3166963B1 (pt) |
JP (1) | JP7094103B2 (pt) |
KR (1) | KR102463632B1 (pt) |
CN (1) | CN107074912B (pt) |
AU (1) | AU2015286723B2 (pt) |
BR (1) | BR112016030577A8 (pt) |
CA (1) | CA2953451C (pt) |
CL (1) | CL2017000064A1 (pt) |
EA (1) | EA035375B1 (pt) |
MX (1) | MX2017000395A (pt) |
MY (1) | MY182440A (pt) |
PE (1) | PE20170291A1 (pt) |
PH (1) | PH12016502468A1 (pt) |
SG (1) | SG11201610456UA (pt) |
WO (1) | WO2016005482A1 (pt) |
ZA (1) | ZA201700165B (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012521786A (ja) | 2009-03-30 | 2012-09-20 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルスワクチン及びその使用 |
SG11201402633UA (en) | 2011-11-28 | 2014-09-26 | Crucell Holland Bv | Influenza virus vaccines and uses thereof |
US9968670B2 (en) | 2012-12-18 | 2018-05-15 | Icahn School Of Medicine At Mount Sinai | Influenza virus vaccines and uses thereof |
US9908930B2 (en) | 2013-03-14 | 2018-03-06 | Icahn School Of Medicine At Mount Sinai | Antibodies against influenza virus hemagglutinin and uses thereof |
MX369317B (es) | 2013-05-30 | 2019-11-05 | Janssen Vaccines & Prevention Bv | Vacunas contra el virus de la influenza y sus usos. |
CN106661091B (zh) | 2014-07-10 | 2020-10-30 | 扬森疫苗与预防公司 | 流行性感冒病毒疫苗及其用途 |
EP3247389A4 (en) | 2015-01-23 | 2019-10-30 | Icahn School of Medicine at Mount Sinai | INFLUENZAVIRUSSCHUTZIMPFPLÄNE |
CN109641041A (zh) | 2016-06-15 | 2019-04-16 | 西奈山伊坎医学院 | 流感病毒血细胞凝集素蛋白及其用途 |
SG10201912944QA (en) * | 2016-09-02 | 2020-02-27 | The Usa As Represented By The Secretary | Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof |
US11254733B2 (en) | 2017-04-07 | 2022-02-22 | Icahn School Of Medicine At Mount Sinai | Anti-influenza B virus neuraminidase antibodies and uses thereof |
CN107765001B (zh) * | 2017-10-24 | 2020-03-27 | 中国科学院苏州纳米技术与纳米仿生研究所 | 禽流感病毒感染或禽流感疫苗免疫分型试剂盒 |
JP7317047B2 (ja) | 2018-01-23 | 2023-07-28 | ヤンセン ファッシンズ アンド プリベンション ベーフェー | インフルエンザウイルスワクチン及びその使用 |
JP7329529B2 (ja) * | 2018-03-28 | 2023-08-18 | サノフィ パスツール インコーポレイテッド | ヘマグルチニンを含む広範に防御的なワクチン組成物を生成する方法 |
TW202016308A (zh) * | 2018-06-27 | 2020-05-01 | 加拿大商苜蓿股份有限公司 | 流感病毒血球凝集素突變體 |
CN109239355B (zh) * | 2018-09-05 | 2020-08-25 | 中牧实业股份有限公司 | 禽流感病毒h9亚型抗体酶联免疫检测试剂盒 |
BR112021005255A2 (pt) | 2018-09-21 | 2021-06-29 | Board Of Regents Of The University Of Nebraska | método de produção e uso de genes para vacina contra a influenza centralizada universal |
KR20220057578A (ko) | 2019-09-05 | 2022-05-09 | 얀센 백신스 앤드 프리벤션 비.브이. | 인플루엔자 바이러스 백신 및 이의 용도 |
GB202004825D0 (en) * | 2020-04-01 | 2020-05-13 | Diosynvax Ltd | Influenza vaccines |
CA3190070A1 (en) * | 2020-09-07 | 2022-03-10 | Martijn Alexander LANGEREIS | Ha stem vaccine for ha antibody-positive targets |
TW202317600A (zh) * | 2021-06-23 | 2023-05-01 | 潤惠生技股份有限公司 | 預防多種病毒感染的多價疫苗 |
WO2023154821A2 (en) * | 2022-02-11 | 2023-08-17 | University Of Washington | Compositions comprising influenza hemagglutinin stem and method for enhancing cross-protective immunity |
WO2023198815A1 (en) | 2022-04-14 | 2023-10-19 | Janssen Vaccines & Prevention B.V. | Sequential administration of adenoviruses |
WO2024104947A2 (en) * | 2022-11-14 | 2024-05-23 | Janssen Vaccines & Prevention B.V. | Influenza b virus vaccines and uses thereof |
CN116589566A (zh) * | 2022-11-18 | 2023-08-15 | 昆明医科大学第一附属医院 | 一种HIV-1中和抗体的改造重组单克隆IgM抗体及其应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2007293662B2 (en) | 2006-09-07 | 2012-10-04 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus H5N1 and uses thereof |
JP2012521786A (ja) * | 2009-03-30 | 2012-09-20 | モウント シナイ スクール オフ メディシネ | インフルエンザウイルスワクチン及びその使用 |
US8470327B2 (en) | 2009-05-11 | 2013-06-25 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza virus H3N2 and uses thereof |
CN102939103A (zh) * | 2010-03-30 | 2013-02-20 | 西奈山医学院 | 流感病毒疫苗及其应用 |
WO2012054745A1 (en) * | 2010-10-20 | 2012-04-26 | New York Blood Center, Inc. | Influenza hemagglutinin-specific monoclonal antibodies for preventing and treating influenza virus infection |
CA2838999C (en) | 2011-07-14 | 2021-02-16 | Crucell Holland B.V. | Human binding molecules capable of neutralizing influenza a viruses of phylogenetic group 1 and phylogenetic group 2 and influenza b viruses |
SG11201402633UA (en) * | 2011-11-28 | 2014-09-26 | Crucell Holland Bv | Influenza virus vaccines and uses thereof |
MX369317B (es) | 2013-05-30 | 2019-11-05 | Janssen Vaccines & Prevention Bv | Vacunas contra el virus de la influenza y sus usos. |
CN106661091B (zh) | 2014-07-10 | 2020-10-30 | 扬森疫苗与预防公司 | 流行性感冒病毒疫苗及其用途 |
-
2015
- 2015-07-09 SG SG11201610456UA patent/SG11201610456UA/en unknown
- 2015-07-09 EP EP15738028.8A patent/EP3166963B1/en active Active
- 2015-07-09 AU AU2015286723A patent/AU2015286723B2/en active Active
- 2015-07-09 EA EA201692467A patent/EA035375B1/ru not_active IP Right Cessation
- 2015-07-09 MY MYPI2017700047A patent/MY182440A/en unknown
- 2015-07-09 WO PCT/EP2015/065663 patent/WO2016005482A1/en active Application Filing
- 2015-07-09 PE PE2017000043A patent/PE20170291A1/es unknown
- 2015-07-09 BR BR112016030577A patent/BR112016030577A8/pt not_active Application Discontinuation
- 2015-07-09 KR KR1020177003528A patent/KR102463632B1/ko active IP Right Grant
- 2015-07-09 MX MX2017000395A patent/MX2017000395A/es unknown
- 2015-07-09 JP JP2017500875A patent/JP7094103B2/ja active Active
- 2015-07-09 CN CN201580037387.0A patent/CN107074912B/zh active Active
- 2015-07-09 US US15/324,939 patent/US10117925B2/en active Active
- 2015-07-09 CA CA2953451A patent/CA2953451C/en active Active
-
2016
- 2016-12-12 PH PH12016502468A patent/PH12016502468A1/en unknown
-
2017
- 2017-01-09 ZA ZA2017/00165A patent/ZA201700165B/en unknown
- 2017-01-10 CL CL2017000064A patent/CL2017000064A1/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2015286723B2 (en) | 2019-11-21 |
SG11201610456UA (en) | 2017-01-27 |
AU2015286723A1 (en) | 2017-01-12 |
MY182440A (en) | 2021-01-25 |
CN107074912A (zh) | 2017-08-18 |
JP2017521073A (ja) | 2017-08-03 |
CA2953451C (en) | 2023-09-19 |
CL2017000064A1 (es) | 2017-11-10 |
CA2953451A1 (en) | 2016-01-14 |
JP7094103B2 (ja) | 2022-07-01 |
WO2016005482A1 (en) | 2016-01-14 |
KR102463632B1 (ko) | 2022-11-03 |
BR112016030577A8 (pt) | 2021-07-20 |
US20170189519A1 (en) | 2017-07-06 |
US10117925B2 (en) | 2018-11-06 |
MX2017000395A (es) | 2018-02-08 |
PH12016502468B1 (en) | 2017-04-10 |
CN107074912B (zh) | 2021-10-29 |
ZA201700165B (en) | 2019-06-26 |
PE20170291A1 (es) | 2017-03-26 |
EP3166963B1 (en) | 2020-04-22 |
EP3166963A1 (en) | 2017-05-17 |
EA035375B1 (ru) | 2020-06-03 |
KR20170027846A (ko) | 2017-03-10 |
PH12016502468A1 (en) | 2017-04-10 |
EA201692467A1 (ru) | 2017-05-31 |
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Legal Events
Date | Code | Title | Description |
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |