BR112016022700A2 - - Google Patents
Info
- Publication number
- BR112016022700A2 BR112016022700A2 BR112016022700A BR112016022700A BR112016022700A2 BR 112016022700 A2 BR112016022700 A2 BR 112016022700A2 BR 112016022700 A BR112016022700 A BR 112016022700A BR 112016022700 A BR112016022700 A BR 112016022700A BR 112016022700 A2 BR112016022700 A2 BR 112016022700A2
- Authority
- BR
- Brazil
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14163442 | 2014-04-03 | ||
| EP14163442.8 | 2014-04-03 | ||
| EP14183823.5 | 2014-09-05 | ||
| EP14183823 | 2014-09-05 | ||
| PCT/EP2015/057401 WO2015150557A1 (en) | 2014-04-03 | 2015-04-02 | Macrocylic pyridine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112016022700A2 true BR112016022700A2 (US07800587-20100921-P00055.png) | 2017-08-15 |
| BR112016022700B1 BR112016022700B1 (pt) | 2022-01-11 |
Family
ID=52781118
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016022700-0A BR112016022700B1 (pt) | 2014-04-03 | 2015-04-02 | Derivados de piridina macrocíclicos e composição farmacêutica que os compreende |
Country Status (22)
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3353341A4 (en) | 2015-09-24 | 2018-10-31 | Cyclenium Pharma Inc. | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same |
| HUE050863T2 (hu) | 2016-02-19 | 2021-01-28 | Sprint Bioscience Ab | Rák és cukorbetegség kezelésére alkalmazható 6-aril-4-(morfolin-4-il)-1H-piridin-2-on vegyületek |
| WO2017140843A1 (en) | 2016-02-19 | 2017-08-24 | Sprint Bioscience Ab | 6-heterocyclyl-4-morpholin-4-ylpyridine-2-one compounds useful for the treatment of cancer and diabetes |
| EP3589285A4 (en) | 2017-02-28 | 2020-08-12 | Morphic Therapeutic, Inc. | INHIBITORS OF INTEGRIN (ALPHA-V) (BETA-6) |
| TW201835078A (zh) | 2017-02-28 | 2018-10-01 | 美商萊築理公司 | αvβ6整合蛋白之抑制劑 |
| US11242356B2 (en) | 2017-03-28 | 2022-02-08 | Bayer Aktiengesellschaft | PTEFb inhibiting macrocyclic compounds |
| PL3601253T3 (pl) | 2017-03-28 | 2022-01-17 | Bayer Aktiengesellschaft | Nowe hamujące ptefb związki makrocykliczne |
| US20200190083A1 (en) * | 2017-06-22 | 2020-06-18 | Cyclenium Pharma Inc. | Libraries of pyridine-containing macrocyclic compounds and methods of making and using the same |
| PT3672941T (pt) | 2017-08-23 | 2022-04-14 | Sprint Bioscience Ab | Compostos de piridilpiridona |
| AU2018321135B2 (en) | 2017-08-23 | 2023-11-23 | Sprint Bioscience Ab | Azaindolylpyridone and diazaindolylpyridone compounds |
| HRP20220497T1 (hr) | 2017-08-23 | 2022-05-27 | Sprint Bioscience Ab | Spoj morfolinilpiridona |
| AU2018320418B2 (en) | 2017-08-23 | 2023-04-06 | Sprint Bioscience Ab | Pyridinamine-pyridone and pyrimidinamine-pyridone compounds |
| SG11202101913PA (en) | 2018-08-29 | 2021-03-30 | Morphic Therapeutic Inc | INHIBITING aV ß6 INTEGRIN |
| CN115260128B (zh) * | 2022-09-21 | 2022-12-09 | 苏州凯瑞医药科技有限公司 | 一种新型jak抑制剂关键中间体的制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001227755A1 (en) * | 2000-01-12 | 2001-07-24 | Merck And Co., Inc. | Inhibitors of prenyl-protein transferase |
| US7151096B2 (en) * | 2003-03-05 | 2006-12-19 | Irm Llc | Cyclic compounds and compositions as protein kinase inhibitors |
| PA8603801A1 (es) * | 2003-05-27 | 2004-12-16 | Janssen Pharmaceutica Nv | Derivados de la quinazolina |
| ES2305887T3 (es) | 2003-12-18 | 2008-11-01 | Janssen Pharmaceutica Nv | Derivados de pirido y pirimidopirimidinas como agentes antiproliferativos. |
| MXPA06007018A (es) | 2003-12-18 | 2006-08-31 | Janssen Pharmaceutica Nv | Derivados de 3-ciano-quinolino con actividad anti-proliferativa. |
| JO3088B1 (ar) | 2004-12-08 | 2017-03-15 | Janssen Pharmaceutica Nv | مشتقات كوينازولين كبيرة الحلقات و استعمالها بصفتها موانع كينيز متعددة الاهداف |
| MY169441A (en) | 2004-12-08 | 2019-04-11 | Janssen Pharmaceutica Nv | 2,4, (4,6) pyrimidine derivatives |
| EP1904461B1 (en) | 2005-06-30 | 2009-08-12 | Janssen Pharmaceutica N.V. | Cyclic anilino-pyridinotriazines as gsk-3 inhibitors |
| TWI525096B (zh) * | 2005-11-16 | 2016-03-11 | Ｃｔｉ生技製藥有限公司 | 氧連接之嘧啶衍生物 |
| DK2170827T3 (da) | 2007-06-21 | 2013-11-18 | Janssen Pharmaceutica Nv | Indolin-2-oner og aza-indolin-2-oner |
| DK2185562T3 (en) | 2007-07-27 | 2016-02-22 | Janssen Pharmaceutica Nv | PYRROLOPYRIMIDINES SUITABLE FOR TREATING PROLIFERATIVE DISEASES |
| WO2009112439A1 (en) * | 2008-03-10 | 2009-09-17 | Janssen Pharmaceutica Nv | 4-aryl-2-anilino-pyrimidines as plk kinase inhibitors |
| BRPI0915105A2 (pt) | 2008-06-13 | 2019-09-24 | Novartis Ag | composto de 2,4'-biripidinila como inibidores da proteína cinase d úteis para o tratamento de ia insuficiência cardíaca e cancer |
-
2015
- 2015-04-01 MA MA039823A patent/MA39823A/fr unknown
- 2015-04-02 KR KR1020167028761A patent/KR102390274B1/ko active IP Right Review Request
- 2015-04-02 CA CA2942751A patent/CA2942751C/en active Active
- 2015-04-02 ES ES15713523.7T patent/ES2665797T3/es active Active
- 2015-04-02 EA EA201692000A patent/EA029758B1/ru not_active IP Right Cessation
- 2015-04-02 CN CN201580018081.0A patent/CN106132964B/zh active Active
- 2015-04-02 AU AU2015239100A patent/AU2015239100B2/en active Active
- 2015-04-02 SG SG11201608241UA patent/SG11201608241UA/en unknown
- 2015-04-02 US US15/300,907 patent/US20170022201A1/en not_active Abandoned
- 2015-04-02 BR BR112016022700-0A patent/BR112016022700B1/pt active IP Right Grant
- 2015-04-02 PE PE2016001843A patent/PE20161365A1/es active IP Right Grant
- 2015-04-02 MY MYPI2016001776A patent/MY185500A/en unknown
- 2015-04-02 NZ NZ725406A patent/NZ725406A/en not_active IP Right Cessation
- 2015-04-02 EP EP15713523.7A patent/EP3126365B1/en active Active
- 2015-04-02 MX MX2016012994A patent/MX369799B/es active IP Right Grant
- 2015-04-02 WO PCT/EP2015/057401 patent/WO2015150557A1/en active Application Filing
- 2015-04-02 UA UAA201611003A patent/UA118120C2/uk unknown
- 2015-04-02 JP JP2016560816A patent/JP6420362B2/ja active Active
-
2016
- 2016-09-25 IL IL248001A patent/IL248001B/en active IP Right Grant
- 2016-09-30 CL CL2016002495A patent/CL2016002495A1/es unknown
- 2016-09-30 ZA ZA2016/06768A patent/ZA201606768B/en unknown
- 2016-10-03 PH PH12016501962A patent/PH12016501962B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR102390274B9 (ko) | 2023-03-03 |
| EP3126365B1 (en) | 2018-01-10 |
| CN106132964A (zh) | 2016-11-16 |
| ZA201606768B (en) | 2018-11-28 |
| PE20161365A1 (es) | 2016-12-17 |
| KR20160140739A (ko) | 2016-12-07 |
| AU2015239100A1 (en) | 2016-09-29 |
| WO2015150557A1 (en) | 2015-10-08 |
| MA39823A (fr) | 2018-01-09 |
| CA2942751C (en) | 2023-03-21 |
| UA118120C2 (uk) | 2018-11-26 |
| NZ725406A (en) | 2022-08-26 |
| JP2017509685A (ja) | 2017-04-06 |
| EA201692000A1 (ru) | 2017-01-30 |
| CA2942751A1 (en) | 2015-10-08 |
| EA029758B1 (ru) | 2018-05-31 |
| IL248001B (en) | 2018-11-29 |
| MX2016012994A (es) | 2016-12-07 |
| KR102390274B1 (ko) | 2022-04-22 |
| EP3126365A1 (en) | 2017-02-08 |
| AU2015239100B2 (en) | 2019-06-27 |
| CL2016002495A1 (es) | 2017-02-24 |
| ES2665797T3 (es) | 2018-04-27 |
| SG11201608241UA (en) | 2016-10-28 |
| MX369799B (es) | 2019-11-21 |
| CN106132964B (zh) | 2019-07-19 |
| US20170022201A1 (en) | 2017-01-26 |
| JP6420362B2 (ja) | 2018-11-07 |
| MY185500A (en) | 2021-05-19 |
| PH12016501962A1 (en) | 2017-01-09 |
| BR112016022700B1 (pt) | 2022-01-11 |
| PH12016501962B1 (en) | 2017-01-09 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B350 | Update of information on the portal [chapter 15.35 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/04/2015, OBSERVADAS AS CONDICOES LEGAIS. |