BR112016022582B1 - Marcadores mitocondriais de doenças neurodegenerativas - Google Patents

Marcadores mitocondriais de doenças neurodegenerativas Download PDF

Info

Publication number
BR112016022582B1
BR112016022582B1 BR112016022582-1A BR112016022582A BR112016022582B1 BR 112016022582 B1 BR112016022582 B1 BR 112016022582B1 BR 112016022582 A BR112016022582 A BR 112016022582A BR 112016022582 B1 BR112016022582 B1 BR 112016022582B1
Authority
BR
Brazil
Prior art keywords
chh
cpg
chg
sites
disease
Prior art date
Application number
BR112016022582-1A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112016022582A2 (pt
Inventor
Marta Barrachina Castillo
Isidre FERRER ABIZANDA
Marta BLANCH LOZANO
Original Assignee
Universitat De Barcelona
Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54150970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112016022582(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Universitat De Barcelona, Fundació Institut D'investigació Biomèdica De Bellvitge (Idibell) filed Critical Universitat De Barcelona
Publication of BR112016022582A2 publication Critical patent/BR112016022582A2/pt
Publication of BR112016022582B1 publication Critical patent/BR112016022582B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/154Methylation markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BR112016022582-1A 2014-03-28 2015-03-27 Marcadores mitocondriais de doenças neurodegenerativas BR112016022582B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP201430444 2014-03-28
ES201430444A ES2546743B1 (es) 2014-03-28 2014-03-28 Marcadores mitocondriales de enfermedades neurodegenerativas
PCT/ES2015/070230 WO2015144964A2 (es) 2014-03-28 2015-03-27 Marcadores mitocondriales de enfermedades neurodegenerativas

Publications (2)

Publication Number Publication Date
BR112016022582A2 BR112016022582A2 (pt) 2017-10-10
BR112016022582B1 true BR112016022582B1 (pt) 2024-03-12

Family

ID=54150970

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016022582-1A BR112016022582B1 (pt) 2014-03-28 2015-03-27 Marcadores mitocondriais de doenças neurodegenerativas

Country Status (10)

Country Link
US (2) US11053549B2 (https=)
EP (1) EP3124621B9 (https=)
JP (1) JP6687532B2 (https=)
AU (1) AU2015238195C1 (https=)
BR (1) BR112016022582B1 (https=)
CA (1) CA2944281C (https=)
DK (1) DK3124621T3 (https=)
ES (2) ES2546743B1 (https=)
PT (1) PT3124621T (https=)
WO (1) WO2015144964A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107904667A (zh) * 2018-01-02 2018-04-13 上海美吉生物医药科技有限公司 一种新型甲基化建库试剂盒及其应用
CN108841928B (zh) * 2018-06-11 2021-11-23 河北医科大学 一种人类线粒体基因组甲基化检测试剂盒及其应用
CN109358194A (zh) * 2018-09-29 2019-02-19 中国海洋大学 凡纳滨对虾高血糖激素间接竞争酶联免疫检测方法
EP4272837A3 (en) 2019-08-02 2024-02-28 Fundacio de Recerca Clinic Barcelona-Institut d'Investigacions Biomèdiques August Pi I Sunyer Car t-cells against bcma for the treatment of multiple myeloma
CN112813159B (zh) * 2021-03-23 2023-05-30 广州金域医学检验中心有限公司 帕金森病的生物标志物及其应用
KR20240160204A (ko) * 2022-03-11 2024-11-08 어드밋 테라퓨틱스 에스엘 알츠하이머병 치매 발병 위험을 결정하는 방법
EP4551720A1 (en) 2022-07-04 2025-05-14 Admit Therapeutics SL Method for identifying dementia with lewy bodies in a subject
CN119144600B (zh) * 2024-11-20 2025-04-01 天津赛萌生物技术有限公司 一种含鲑鱼线粒体基因克隆载体的构建及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110223B2 (ja) 1997-02-27 2008-07-02 インジェネウス・インコーポレーテッド Pnaプローブを用いる、溶液中でのヌクレオチドアッセイ法
JP2003521879A (ja) * 1999-04-20 2003-07-22 マイトコー アルツハイマー病とともに分離するミトコンドリア遺伝子における一塩基多型
WO2003046225A1 (en) 2001-11-26 2003-06-05 Mitokor Mitochondrial dna polymorphisms
JP2005000044A (ja) 2003-06-10 2005-01-06 Masatsugu Tanaka ヒトミトコンドリア遺伝子変異に基づく遺伝子検出法
US20120232016A1 (en) 2011-03-08 2012-09-13 Coleman Paul D Method and system to detect and diagnose alzheimer's disease

Also Published As

Publication number Publication date
PT3124621T (pt) 2019-09-23
US12065702B2 (en) 2024-08-20
EP3124621B9 (en) 2020-10-21
AU2015238195A1 (en) 2016-10-27
US20170137881A1 (en) 2017-05-18
WO2015144964A2 (es) 2015-10-01
CA2944281A1 (en) 2015-10-01
EP3124621B1 (en) 2019-06-05
DK3124621T3 (da) 2019-09-09
AU2015238195C1 (en) 2022-03-10
BR112016022582A2 (pt) 2017-10-10
JP6687532B2 (ja) 2020-04-28
WO2015144964A3 (es) 2015-12-17
ES2546743B1 (es) 2016-07-07
ES2546743A1 (es) 2015-09-28
ES2744592T3 (es) 2020-02-25
EP3124621A2 (en) 2017-02-01
US20220049307A1 (en) 2022-02-17
CA2944281C (en) 2021-05-18
ES2744592T9 (es) 2020-12-15
EP3124621A4 (en) 2018-02-14
US11053549B2 (en) 2021-07-06
JP2017511138A (ja) 2017-04-20
AU2015238195B2 (en) 2019-07-18

Similar Documents

Publication Publication Date Title
US12065702B2 (en) Mitochondrial markers of neurodegenerative diseases
US6475736B1 (en) Methods for genetic analysis of DNA using biased amplification of polymorphic sites
US20140193809A1 (en) Methods for genetic analysis of dna to detect sequence variances
JP2020089370A (ja) 抗精神病薬に基づく処置により誘導される錐体外路症状(eps)の発症を予測する方法
KR101761801B1 (ko) 코 표현형 판단용 조성물
US20050191652A1 (en) Identification of genetic forms of a gene that leads to high risk for parkinson disease
US20030082537A1 (en) Methods for genetic analysis of DNA to detect sequence variances
AU2007231141B2 (en) Hereditary cataract status in canines based on HSF4 gene marker
CA3174572A1 (en) Compositions and methods for assessing the efficacy of inhibitors of neurotransmitter transporters
WO2015016392A1 (ja) 筋萎縮性側索硬化症の新規病因遺伝子
KR102281657B1 (ko) 지연성 허혈 진단을 위한 cdhr5 유전자 과메틸화 마커
KR102281644B1 (ko) 지연성 허혈 진단을 위한 insr 유전자 과메틸화 마커
JP4859088B2 (ja) 2型糖尿病に関連するヒトwnt5b遺伝子多型の検出方法及びキット
JP4998874B2 (ja) 炎症性疾患の判定方法
KR102110883B1 (ko) 정신 질환 진단용 kmt2c 다형성 마커
JP2004159524A (ja) 核酸試料中のヒトセロトニン5−ht4受容体遺伝子の型を検出する方法
KR20190063026A (ko) 폐암 환자의 변증 구분용 snp 마커 및 이의 용도
WO2016123543A1 (en) Method for treating schizophrenia comprising administering lurasidone

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/03/2015, OBSERVADAS AS CONDICOES LEGAIS