BR112016022582A2 - ?marcadores mitocondriais de doenças neurodegenerativas? - Google Patents

?marcadores mitocondriais de doenças neurodegenerativas?

Info

Publication number
BR112016022582A2
BR112016022582A2 BR112016022582A BR112016022582A BR112016022582A2 BR 112016022582 A2 BR112016022582 A2 BR 112016022582A2 BR 112016022582 A BR112016022582 A BR 112016022582A BR 112016022582 A BR112016022582 A BR 112016022582A BR 112016022582 A2 BR112016022582 A2 BR 112016022582A2
Authority
BR
Brazil
Prior art keywords
neurodegenerative diseases
determining
individual
mitochondrial
mitochondrial markers
Prior art date
Application number
BR112016022582A
Other languages
English (en)
Other versions
BR112016022582B1 (pt
Inventor
Ferrer Abizanda Isidre
Barrachina Castillo Marta
Blanch Lozano Marta
Original Assignee
Fundacio Inst Dinvestigacio Biomedica De Bellvitge Idibell
Univ Barcelona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=54150970&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112016022582(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fundacio Inst Dinvestigacio Biomedica De Bellvitge Idibell, Univ Barcelona filed Critical Fundacio Inst Dinvestigacio Biomedica De Bellvitge Idibell
Publication of BR112016022582A2 publication Critical patent/BR112016022582A2/pt
Publication of BR112016022582B1 publication Critical patent/BR112016022582B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

resumo da patente de invenção para: ?marcadores mitocondriais de doenças neurodegenerativas?. a presente invenção refere-se a um método in vitro para diagnosticar ou para determinar o risco de desenvolver uma doença neurodegenerativa em um indivíduo baseado na determinação do padrão de metilação em certas regiões do adn mitocondrial do dito indivíduo ou na determinação do nucleótido na posição polimórfica 16519 do adn mitocondrial do dito indivíduo. finalmente, a presente invenção refere-se a ácidos nucleicos adequados para poner em prática a invenção.
BR112016022582-1A 2014-03-28 2015-03-27 Marcadores mitocondriais de doenças neurodegenerativas BR112016022582B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ESP201430444 2014-03-28
ES201430444A ES2546743B1 (es) 2014-03-28 2014-03-28 Marcadores mitocondriales de enfermedades neurodegenerativas
PCT/ES2015/070230 WO2015144964A2 (es) 2014-03-28 2015-03-27 Marcadores mitocondriales de enfermedades neurodegenerativas

Publications (2)

Publication Number Publication Date
BR112016022582A2 true BR112016022582A2 (pt) 2017-10-10
BR112016022582B1 BR112016022582B1 (pt) 2024-03-12

Family

ID=54150970

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016022582-1A BR112016022582B1 (pt) 2014-03-28 2015-03-27 Marcadores mitocondriais de doenças neurodegenerativas

Country Status (10)

Country Link
US (2) US11053549B2 (pt)
EP (1) EP3124621B9 (pt)
JP (1) JP6687532B2 (pt)
AU (1) AU2015238195C1 (pt)
BR (1) BR112016022582B1 (pt)
CA (1) CA2944281C (pt)
DK (1) DK3124621T3 (pt)
ES (2) ES2546743B1 (pt)
PT (1) PT3124621T (pt)
WO (1) WO2015144964A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107904667A (zh) * 2018-01-02 2018-04-13 上海美吉生物医药科技有限公司 一种新型甲基化建库试剂盒及其应用
CN108841928B (zh) * 2018-06-11 2021-11-23 河北医科大学 一种人类线粒体基因组甲基化检测试剂盒及其应用
CN109358194A (zh) * 2018-09-29 2019-02-19 中国海洋大学 凡纳滨对虾高血糖激素间接竞争酶联免疫检测方法
CN112813159B (zh) * 2021-03-23 2023-05-30 广州金域医学检验中心有限公司 帕金森病的生物标志物及其应用
AU2023231454A1 (en) 2022-03-11 2024-07-11 Admit Therapeutics Sl Methods of determining the risk of developing alzheimer's disease dementia
WO2024008759A1 (en) 2022-07-04 2024-01-11 Admit Therapeutics Sl Method for identifying dementia with lewy bodies in a subject

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0975800T3 (da) 1997-02-27 2003-09-22 Ingeneus Corp Analyse af nukleotider i opløsning under anvendelse af PNA-prober
EP1208225A2 (en) * 1999-04-20 2002-05-29 Mitokor Single nucleotide polymorphisms in mitochondrial genes that segregate with alzheimer's disease
US20040029133A1 (en) * 2001-11-26 2004-02-12 Mitokor, Inc. Mitochondrial DNA polymorphisms
JP2005000044A (ja) * 2003-06-10 2005-01-06 Masatsugu Tanaka ヒトミトコンドリア遺伝子変異に基づく遺伝子検出法
US20120232016A1 (en) * 2011-03-08 2012-09-13 Coleman Paul D Method and system to detect and diagnose alzheimer's disease

Also Published As

Publication number Publication date
PT3124621T (pt) 2019-09-23
DK3124621T3 (da) 2019-09-09
ES2546743B1 (es) 2016-07-07
JP6687532B2 (ja) 2020-04-28
JP2017511138A (ja) 2017-04-20
BR112016022582B1 (pt) 2024-03-12
ES2546743A1 (es) 2015-09-28
AU2015238195A1 (en) 2016-10-27
EP3124621B9 (en) 2020-10-21
EP3124621B1 (en) 2019-06-05
AU2015238195B2 (en) 2019-07-18
US12065702B2 (en) 2024-08-20
ES2744592T3 (es) 2020-02-25
US11053549B2 (en) 2021-07-06
CA2944281A1 (en) 2015-10-01
EP3124621A4 (en) 2018-02-14
US20170137881A1 (en) 2017-05-18
WO2015144964A2 (es) 2015-10-01
WO2015144964A3 (es) 2015-12-17
EP3124621A2 (en) 2017-02-01
CA2944281C (en) 2021-05-18
US20220049307A1 (en) 2022-02-17
AU2015238195C1 (en) 2022-03-10
ES2744592T9 (es) 2020-12-15

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/03/2015, OBSERVADAS AS CONDICOES LEGAIS