BR112016013623A2 - - Google Patents

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Publication number
BR112016013623A2
BR112016013623A2 BR112016013623A BR112016013623A BR112016013623A2 BR 112016013623 A2 BR112016013623 A2 BR 112016013623A2 BR 112016013623 A BR112016013623 A BR 112016013623A BR 112016013623 A BR112016013623 A BR 112016013623A BR 112016013623 A2 BR112016013623 A2 BR 112016013623A2
Authority
BR
Brazil
Application number
BR112016013623A
Other versions
BR112016013623B1 (pt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR112016013623A2 publication Critical patent/BR112016013623A2/pt
Publication of BR112016013623B1 publication Critical patent/BR112016013623B1/pt

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0676Pancreatic cells
    • C12N5/0677Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/507Pancreatic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/14Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from hepatocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • C12N2533/32Polylysine, polyornithine

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
BR112016013623-3A 2013-12-16 2014-12-16 Método de preparação de uma estrutura de célula esferoide semelhante à ilhota pancreática cultivada artificialmente, e uso de uma estrutura de célula esferoide BR112016013623B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13197368 2013-12-16
EP13197368.7 2013-12-16
PCT/EP2014/077976 WO2015091493A1 (en) 2013-12-16 2014-12-16 Pancreatic islet-like cell structures and a method of preparing thereof

Publications (2)

Publication Number Publication Date
BR112016013623A2 true BR112016013623A2 (pt) 2017-08-08
BR112016013623B1 BR112016013623B1 (pt) 2023-03-21

Family

ID=49765387

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016013623-3A BR112016013623B1 (pt) 2013-12-16 2014-12-16 Método de preparação de uma estrutura de célula esferoide semelhante à ilhota pancreática cultivada artificialmente, e uso de uma estrutura de célula esferoide

Country Status (11)

Country Link
US (2) US10174286B2 (pt)
EP (1) EP3083941B1 (pt)
JP (2) JP6643993B2 (pt)
KR (1) KR102338815B1 (pt)
CN (2) CN111635883A (pt)
AU (1) AU2014364632B2 (pt)
BR (1) BR112016013623B1 (pt)
CA (1) CA2933135C (pt)
DK (1) DK3083941T3 (pt)
ES (1) ES2941686T3 (pt)
WO (1) WO2015091493A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ603482A (en) 2010-05-12 2014-11-28 Tengion Inc Bioactive renal cells
WO2020035480A1 (en) 2018-08-16 2020-02-20 Unicyte Islet Ag Viable pancreatic islet-like cell structures and a method of preparing thereof
EP3816276A1 (en) 2019-10-31 2021-05-05 Unicyte Islet AG Viable pancreatic islet-like cell structures and a method of preparing thereof
CN113637630B (zh) * 2020-05-11 2024-03-29 中国科学院分子细胞科学卓越创新中心 一种胰岛样细胞团及其制法和应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0348490B1 (en) * 1988-01-11 1995-09-27 Amylin Pharmaceuticals, Inc. Treatment of type 2 diabetes mellitus
AU4330597A (en) * 1996-08-30 1998-03-19 Life Technologies, Inc. Serum-free mammalian cell culture medium, and uses thereof
US6129911A (en) 1998-07-10 2000-10-10 Rhode Island Hospital, A Lifespan Partner Liver stem cell
DK1147179T3 (da) 1999-01-19 2009-03-09 Univ North Carolina Humane lever-progenitorer
US7456017B2 (en) 1999-10-01 2008-11-25 University Of North Carolina At Chapel Hill Processes for clonal growth of hepatic progenitor cells
US20010046489A1 (en) * 1999-12-06 2001-11-29 Habener Joel E. Stem cells of the islets of langerhans and their use in treating diabetes mellitus
JP4344231B2 (ja) 2001-05-16 2009-10-14 財団法人神奈川科学技術アカデミー dlkを用いた未分化肝細胞の検出及び分離方法
EP1264879A1 (en) * 2001-06-08 2002-12-11 Leadd B.V. Isolation of a cluster of cells from an isolated organ using magnetic particle
US20050053588A1 (en) 2001-10-18 2005-03-10 Li Yin Conversion of liver stem and progenitor cells to pancreatic functional cells
CA2692325C (en) * 2001-12-07 2015-10-20 Geron Corporation Islet cells from human embryonic stem cells
US20030162290A1 (en) * 2002-01-25 2003-08-28 Kazutomo Inoue Method for inducing differentiation of embryonic stem cells into functioning cells
HUE032238T2 (en) 2002-03-15 2017-09-28 Univ North Carolina Chapel Hill Primitive and proximal liver stem cells
CN1536075A (zh) * 2003-04-09 2004-10-13 中国人民解放军军事医学科学院野战输 一种诱导骨髓间充质干细胞向胰岛样细胞分化的方法
CA2531312A1 (en) * 2003-07-29 2005-02-17 Unilever Plc Food product comprising phytosterols
US20050074876A1 (en) 2003-10-03 2005-04-07 Inserm Bipotential liver cell lines from wild-type mammalian liver tissue
US7485434B2 (en) * 2005-04-04 2009-02-03 The Salk Institute For Biological Studies Method for screening compounds for those that modulate transducers of regulated CREB activity
US7507581B2 (en) * 2005-04-05 2009-03-24 Synthecon, Inc. Inhibition of pancreatic islet aggregation
WO2006126219A1 (en) * 2005-05-26 2006-11-30 Fresenius Medical Care Deutschland G.M.B.H. Liver progenitor cells
JP5131833B2 (ja) * 2005-10-05 2013-01-30 晃文 松山 脂肪組織由来細胞から膵内分泌細胞を得る方法
CN101356264B (zh) * 2005-12-21 2014-05-14 鲁汶大学 分离的肝脏干细胞
US7716503B2 (en) 2006-12-14 2010-05-11 Inventec Corporation Extension card incorporating power management device
JP5196522B2 (ja) * 2007-06-27 2013-05-15 国立大学法人東北大学 移植用膵島の評価方法
CN101896188B (zh) * 2007-10-15 2013-01-02 弗雷森纽斯医疗护理德国有限责任公司 微泡(mv)用于制备对内皮细胞移植具有佐剂活性、特别是对通过胰岛移植进行的糖尿病治疗具有佐剂活性的药物的用途,和相关方法
GB0800524D0 (en) * 2008-01-14 2008-02-20 Univ Brighton Cell culture system
US20110008301A1 (en) * 2008-03-15 2011-01-13 Trivedi H L Human adipose derived insulin making mesenchymal stem cells for treating diabetes mellitus
CN101550406B (zh) 2008-04-03 2016-02-10 北京大学 制备多潜能干细胞的方法,试剂盒及用途
CN101603027A (zh) * 2008-06-12 2009-12-16 西北农林科技大学 体外诱导人骨髓间充质干细胞分化为胰岛样细胞的方法
EP2393917B1 (en) * 2009-02-03 2016-04-06 Koninklijke Nederlandse Akademie van Wetenschappen Culture medium for epithelial stem cells and organoids comprising said stem cells.
CN102433300A (zh) * 2011-11-25 2012-05-02 厚朴生物科技(苏州)有限公司 一种人胰岛来源的胰腺干细胞系的构建及向胰岛素分泌细胞分化的方法
CN102517248A (zh) * 2011-12-30 2012-06-27 中日友好医院 一种体外诱导胰岛样结构形成的方法

Also Published As

Publication number Publication date
US11453863B2 (en) 2022-09-27
KR20160098439A (ko) 2016-08-18
US10174286B2 (en) 2019-01-08
AU2014364632B2 (en) 2021-04-01
ES2941686T3 (es) 2023-05-24
JP2017500859A (ja) 2017-01-12
CA2933135C (en) 2023-08-01
DK3083941T3 (da) 2023-03-13
EP3083941B1 (en) 2023-02-22
WO2015091493A1 (en) 2015-06-25
CA2933135A1 (en) 2015-06-25
KR102338815B1 (ko) 2021-12-13
AU2014364632A1 (en) 2016-06-16
BR112016013623B1 (pt) 2023-03-21
CN111635883A (zh) 2020-09-08
CN105814193A (zh) 2016-07-27
CN105814193B (zh) 2020-05-08
EP3083941A1 (en) 2016-10-26
US20190119648A1 (en) 2019-04-25
JP6643993B2 (ja) 2020-02-12
JP2020014477A (ja) 2020-01-30
US20160312189A1 (en) 2016-10-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/12/2014, OBSERVADAS AS CONDICOES LEGAIS