BR112016009393A8 - método para produzir um agrupamento (cluster) de células tridimensional, e método não enzimático para iniciar a cultura de suspensão de células pluripotentes a partir de uma cultura aderente ou planar - Google Patents
método para produzir um agrupamento (cluster) de células tridimensional, e método não enzimático para iniciar a cultura de suspensão de células pluripotentes a partir de uma cultura aderente ou planar Download PDFInfo
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- BR112016009393A8 BR112016009393A8 BR112016009393A BR112016009393A BR112016009393A8 BR 112016009393 A8 BR112016009393 A8 BR 112016009393A8 BR 112016009393 A BR112016009393 A BR 112016009393A BR 112016009393 A BR112016009393 A BR 112016009393A BR 112016009393 A8 BR112016009393 A8 BR 112016009393A8
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- Brazil
- Prior art keywords
- culture
- adherent
- initiating
- producing
- cells
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- 230000001464 adherent effect Effects 0.000 title 1
- 238000006911 enzymatic reaction Methods 0.000 title 1
- 230000000977 initiatory effect Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000004114 suspension culture Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 3
- 210000004027 cell Anatomy 0.000 abstract 2
- 230000004069 differentiation Effects 0.000 abstract 2
- 210000000227 basophil cell of anterior lobe of hypophysis Anatomy 0.000 abstract 1
- 210000002064 heart cell Anatomy 0.000 abstract 1
- 210000002569 neuron Anatomy 0.000 abstract 1
- 210000001778 pluripotent stem cell Anatomy 0.000 abstract 1
- 238000011176 pooling Methods 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361962158P | 2013-11-01 | 2013-11-01 | |
| US13/998,974 US10377989B2 (en) | 2012-12-31 | 2013-12-30 | Methods for suspension cultures of human pluripotent stem cells |
| PCT/US2014/042796 WO2015065537A1 (en) | 2013-11-01 | 2014-06-17 | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112016009393A8 true BR112016009393A8 (pt) | 2020-03-24 |
Family
ID=53004904
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016009393A BR112016009393A8 (pt) | 2013-11-01 | 2014-06-17 | método para produzir um agrupamento (cluster) de células tridimensional, e método não enzimático para iniciar a cultura de suspensão de células pluripotentes a partir de uma cultura aderente ou planar |
Country Status (12)
| Country | Link |
|---|---|
| EP (2) | EP3063268A4 (https=) |
| JP (2) | JP2016534731A (https=) |
| KR (4) | KR20180128529A (https=) |
| CN (2) | CN105793413A (https=) |
| AU (4) | AU2014342995C1 (https=) |
| BR (1) | BR112016009393A8 (https=) |
| CA (2) | CA2928639A1 (https=) |
| MX (2) | MX2016005657A (https=) |
| PH (2) | PH12016500782A1 (https=) |
| RU (2) | RU2689710C2 (https=) |
| SG (2) | SG11201603045VA (https=) |
| WO (2) | WO2015065524A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015065524A2 (en) * | 2013-11-01 | 2015-05-07 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
| JP7637323B2 (ja) * | 2016-06-23 | 2025-02-28 | ティソン バイオテック,インコーポレイテッド | 副甲状腺ホルモン1型受容体を発現する細胞およびその使用 |
| CA3042495A1 (en) | 2016-11-10 | 2018-05-17 | Viacyte, Inc. | Pdx1 pancreatic endoderm cells in cell delivery devices and methods thereof |
| MX2019005476A (es) * | 2016-11-16 | 2019-07-04 | Cynata Therapeutics Ltd | Ensayo de celulas madre pluripotentes. |
| US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
| CN111246864A (zh) * | 2017-07-21 | 2020-06-05 | 森玛治疗公司 | 干细胞衍生的胰腺β细胞的重聚 |
| JP7000896B2 (ja) * | 2017-08-23 | 2022-01-19 | 王子ホールディングス株式会社 | 細胞シート形成部材、細胞シート形成部材の製造方法、および、細胞シートの製造方法 |
| JP2021509812A (ja) * | 2018-01-05 | 2021-04-08 | プレートレット バイオジェネシス, インコーポレイテッド | 巨核球を産生するための組成物および方法 |
| CN112041428B (zh) * | 2018-01-18 | 2024-05-24 | 新加坡科技研究局 | 用于在悬浮培养物中分化人多能干细胞系的方法 |
| KR102115360B1 (ko) * | 2018-05-30 | 2020-05-26 | 주식회사 바이블리오테카 | 성체 줄기세포 배양액 및 그 제조방법 |
| US12378572B2 (en) | 2018-09-07 | 2025-08-05 | Crispr Therapeutics Ag | Universal donor cells |
| CN114173837A (zh) | 2019-05-31 | 2022-03-11 | W.L.戈尔及同仁股份有限公司 | 生物相容性膜复合材料 |
| CA3139292C (en) | 2019-05-31 | 2025-06-10 | Viacyte, Inc. | CELL ENCAPSULATION DEVICES WITH REGULATED OXYGEN DIFFUSION DISTANCES |
| EP3975926A1 (en) | 2019-05-31 | 2022-04-06 | W.L. Gore & Associates, Inc. | A biocompatible membrane composite |
| EP3976236A1 (en) | 2019-05-31 | 2022-04-06 | W.L. Gore & Associates Inc. | A biocompatible membrane composite |
| US20210062157A1 (en) * | 2019-08-27 | 2021-03-04 | United Therapeutics Corporation | Methods and compositions for culturing alveolar cells |
| CA3150235A1 (en) | 2019-09-05 | 2021-03-11 | Alireza Rezania | Universal donor cells |
| PH12022550542A1 (en) | 2019-09-05 | 2023-03-20 | Crispr Therapeutics Ag | Universal donor cells |
| CN114729323B (zh) * | 2019-11-22 | 2024-09-17 | 诺和诺德股份有限公司 | 旋转聚集的神经微球及其应用 |
| WO2022144855A1 (en) | 2020-12-31 | 2022-07-07 | Crispr Therapeutics Ag | Universal donor cells |
| JPWO2022203051A1 (https=) * | 2021-03-25 | 2022-09-29 | ||
| JP2022151855A (ja) * | 2021-03-25 | 2022-10-07 | 株式会社カネカ | 多能性幹細胞集団の製造方法 |
| CN116218766A (zh) * | 2023-04-21 | 2023-06-06 | 北京意胜生物科技有限公司 | 一种制备胰腺前体细胞的方法、培养基及其应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090115984A (ko) * | 2001-11-09 | 2009-11-10 | 아르테셀 사이언스, 인크. | 지방 조직에서 유래된 기질세포의 내분비 췌장 분화 및 이의 용도 |
| DK3441459T3 (da) * | 2006-08-02 | 2021-06-07 | Technion Res & Dev Foundation | Fremgangsmåder til ekspansion af embryonale stamceller i en suspensionskultur |
| EP2088190A4 (en) * | 2006-11-09 | 2011-01-05 | Japan Government | METHOD FOR THE CULTURE AND PASSING OF AN EMBRYONAL PRIMATIVE STEM CELL AND METHOD FOR INDUCING THE DIFFERENTIATION OF THE EMBRYONAL STEM CELL |
| US20090053182A1 (en) * | 2007-05-25 | 2009-02-26 | Medistem Laboratories, Inc. | Endometrial stem cells and methods of making and using same |
| EP2559756B1 (en) * | 2007-07-01 | 2019-12-18 | Janssen Biotech, Inc. | Single pluripotent stem cell culture |
| JP2011514169A (ja) * | 2008-03-17 | 2011-05-06 | エージェンシー フォー サイエンス,テクノロジー アンド リサーチ | 幹細胞培養のためのマイクロキャリア |
| EP2942392B1 (en) * | 2008-06-30 | 2018-10-03 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
| US8008075B2 (en) * | 2008-11-04 | 2011-08-30 | Viacyte, Inc. | Stem cell aggregate suspension compositions and methods of differentiation thereof |
| WO2011019092A1 (en) * | 2009-08-12 | 2011-02-17 | Kyoto University | Method for inducing differentiation of pluripotent stem cells into neural precursor cells |
| JP5936134B2 (ja) * | 2010-06-15 | 2016-06-15 | 国立大学法人京都大学 | ヒト人工多能性幹細胞の選択方法 |
| PL2853589T3 (pl) * | 2010-08-31 | 2018-05-30 | Janssen Biotech, Inc | Różnicowanie ludzkich zarodkowych komórek macierzystych |
| MY177150A (en) * | 2011-02-28 | 2020-09-08 | Stempeutics Res Malaysia Sdn Bhd | Isolation and expansion of adult stem cells, their therapeutic composition and uses thereof |
| US8951798B2 (en) * | 2011-10-13 | 2015-02-10 | Wisconsin Alumni Research Foundation | Generation of cardiomyocytes from human pluripotent stem cells |
| FI2794857T3 (fi) * | 2011-12-22 | 2026-03-25 | Janssen Biotech Inc | Ihmisen alkion kantasolujen erilaistaminen yksittäisiksi hormonaalisiksi insuliinipositiivisiksi soluiksi |
| US10519422B2 (en) * | 2012-02-29 | 2019-12-31 | Riken | Method of producing human retinal pigment epithelial cells |
| BR112015015714A2 (pt) * | 2012-12-31 | 2017-07-11 | Janssen Biotech Inc | suspensão e aglomeração de células pluripotentes humanas para diferenciação em célu-las endócrinas pancreáticas |
| WO2015065524A2 (en) * | 2013-11-01 | 2015-05-07 | Janssen Biotech, Inc. | Suspension and clustering of human pluripotent stem cells for differentiation into pancreatic endocrine cells |
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- 2014-05-21 EP EP14857034.4A patent/EP3063268A4/en not_active Withdrawn
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