BR112016007401A2 - métodos e processos para avaliação não invasiva das variações genéticas - Google Patents
métodos e processos para avaliação não invasiva das variações genéticasInfo
- Publication number
- BR112016007401A2 BR112016007401A2 BR112016007401A BR112016007401A BR112016007401A2 BR 112016007401 A2 BR112016007401 A2 BR 112016007401A2 BR 112016007401 A BR112016007401 A BR 112016007401A BR 112016007401 A BR112016007401 A BR 112016007401A BR 112016007401 A2 BR112016007401 A2 BR 112016007401A2
- Authority
- BR
- Brazil
- Prior art keywords
- processes
- methods
- genetic variations
- noninvasive evaluation
- noninvasive
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 230000007614 genetic variation Effects 0.000 title abstract 3
- 238000011156 evaluation Methods 0.000 title 1
Classifications
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/10—Ploidy or copy number detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B30/00—ICT specially adapted for sequence analysis involving nucleotides or amino acids
- G16B30/10—Sequence alignment; Homology search
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Computational Biology (AREA)
- Evolutionary Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioethics (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Software Systems (AREA)
- Public Health (AREA)
- Evolutionary Computation (AREA)
- Epidemiology (AREA)
- Databases & Information Systems (AREA)
- Artificial Intelligence (AREA)
- Data Mining & Analysis (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Pathology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
resumo métodos e processos para avaliação não invasiva das variações genéticas aqui fornecido são métodos, processos, sistemas e máquinas para avaliação não invasiva das variações genéticas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361887081P | 2013-10-04 | 2013-10-04 | |
US61/887,081 | 2013-10-04 | ||
PCT/US2014/058885 WO2015051163A2 (en) | 2013-10-04 | 2014-10-02 | Methods and processes for non-invasive assessment of genetic variations |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112016007401A2 true BR112016007401A2 (pt) | 2017-08-01 |
BR112016007401B1 BR112016007401B1 (pt) | 2023-04-11 |
Family
ID=51842830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112016007401-7A BR112016007401B1 (pt) | 2013-10-04 | 2014-10-02 | Método para determinar a presença ou ausência de uma aneuploidia cromossômica em uma amostra |
Country Status (15)
Country | Link |
---|---|
US (2) | US10964409B2 (pt) |
EP (2) | EP3053071B1 (pt) |
JP (4) | JP6525434B2 (pt) |
KR (3) | KR20230044325A (pt) |
CN (2) | CN110176273B (pt) |
AU (3) | AU2014329493B2 (pt) |
BR (1) | BR112016007401B1 (pt) |
CA (2) | CA3205430A1 (pt) |
DK (1) | DK3053071T3 (pt) |
ES (1) | ES2968644T3 (pt) |
FI (1) | FI3053071T3 (pt) |
IL (5) | IL295860B2 (pt) |
MY (1) | MY181069A (pt) |
PL (1) | PL3053071T3 (pt) |
WO (1) | WO2015051163A2 (pt) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140235474A1 (en) | 2011-06-24 | 2014-08-21 | Sequenom, Inc. | Methods and processes for non invasive assessment of a genetic variation |
US10196681B2 (en) | 2011-10-06 | 2019-02-05 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US20140242588A1 (en) | 2011-10-06 | 2014-08-28 | Sequenom, Inc | Methods and processes for non-invasive assessment of genetic variations |
US10424394B2 (en) | 2011-10-06 | 2019-09-24 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US9984198B2 (en) | 2011-10-06 | 2018-05-29 | Sequenom, Inc. | Reducing sequence read count error in assessment of complex genetic variations |
US9367663B2 (en) | 2011-10-06 | 2016-06-14 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
CA2861856C (en) | 2012-01-20 | 2020-06-02 | Sequenom, Inc. | Diagnostic processes that factor experimental conditions |
US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US10497461B2 (en) | 2012-06-22 | 2019-12-03 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US10482994B2 (en) | 2012-10-04 | 2019-11-19 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US20130309666A1 (en) | 2013-01-25 | 2013-11-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
FI2981921T3 (fi) | 2013-04-03 | 2023-03-09 | Sequenom Inc | Menetelmiä ja prosesseja geneettisten variaatioiden ei-invasiiviseen arviointiin |
KR102665592B1 (ko) | 2013-05-24 | 2024-05-21 | 시쿼넘, 인코포레이티드 | 유전적 변이의 비침습 평가를 위한 방법 및 프로세스 |
HUE042654T2 (hu) | 2013-06-21 | 2019-07-29 | Sequenom Inc | Eljárás genetikai variációk nem-invazív megállapítására |
MY181069A (en) | 2013-10-04 | 2020-12-17 | Sequenom Inc | Methods and processes for non-invasive assessment of genetic variations |
CN111863131A (zh) | 2013-10-07 | 2020-10-30 | 塞昆纳姆股份有限公司 | 用于非侵入性评估染色体改变的方法和过程 |
WO2015138774A1 (en) | 2014-03-13 | 2015-09-17 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
CA3191504A1 (en) | 2014-05-30 | 2015-12-03 | Sequenom, Inc. | Chromosome representation determinations |
US10490299B2 (en) * | 2014-06-06 | 2019-11-26 | Battelle Memorial Institute | Identification of traits associated with DNA samples using epigenetic-based patterns detected via massively parallel sequencing |
EP3760739A1 (en) | 2014-07-30 | 2021-01-06 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
EP3730629A1 (en) | 2014-10-10 | 2020-10-28 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US9544321B2 (en) * | 2015-01-30 | 2017-01-10 | Securonix, Inc. | Anomaly detection using adaptive behavioral profiles |
US10395759B2 (en) | 2015-05-18 | 2019-08-27 | Regeneron Pharmaceuticals, Inc. | Methods and systems for copy number variant detection |
EP3303663A4 (en) * | 2015-05-28 | 2019-07-03 | Genepeeks, Inc. | SYSTEMS AND METHOD FOR IMPROVED PREDICTION OF A CARRIER STATE FOR SPINAL MUSCLE ATROPHY |
US10551302B2 (en) * | 2015-08-13 | 2020-02-04 | Halliburton Energy Services, Inc. | Calibration of optical computing devices using traceable filters |
WO2017062505A1 (en) * | 2015-10-05 | 2017-04-13 | Cedars-Sinai Medical Center | Method of classifying and diagnosing cancer |
US9848301B2 (en) * | 2015-11-20 | 2017-12-19 | At&T Intellectual Property I, L.P. | Facilitation of mobile device geolocation |
EP3464626B1 (en) | 2016-05-27 | 2022-04-06 | Sequenom, Inc. | Methods for detecting genetic variations |
US10809266B2 (en) * | 2016-07-22 | 2020-10-20 | Verily Life Sciences Llc | Quantitative massively parallel proteomics |
CA3030894A1 (en) | 2016-07-27 | 2018-02-01 | Sequenom, Inc. | Methods for non-invasive assessment of genomic instability |
CA3030890A1 (en) | 2016-07-27 | 2018-02-01 | Sequenom, Inc. | Genetic copy number alteration classifications |
US9998876B2 (en) | 2016-07-27 | 2018-06-12 | At&T Intellectual Property I, L.P. | Inferring user equipment location data based on sector transition |
US11205103B2 (en) | 2016-12-09 | 2021-12-21 | The Research Foundation for the State University | Semisupervised autoencoder for sentiment analysis |
CN106650312B (zh) * | 2016-12-29 | 2022-05-17 | 浙江安诺优达生物科技有限公司 | 一种用于循环肿瘤dna拷贝数变异检测的装置 |
CN106845154B (zh) * | 2016-12-29 | 2022-04-08 | 浙江安诺优达生物科技有限公司 | 一种用于ffpe样本拷贝数变异检测的装置 |
WO2018136882A1 (en) | 2017-01-20 | 2018-07-26 | Sequenom, Inc. | Methods for non-invasive assessment of copy number alterations |
EP3571317A1 (en) | 2017-01-20 | 2019-11-27 | Sequenom, Inc. | Sequencing adapter manufacture and use |
US11929145B2 (en) | 2017-01-20 | 2024-03-12 | Sequenom, Inc | Methods for non-invasive assessment of genetic alterations |
WO2018140521A1 (en) | 2017-01-24 | 2018-08-02 | Sequenom, Inc. | Methods and processes for assessment of genetic variations |
JP7370862B2 (ja) | 2017-03-17 | 2023-10-30 | セクエノム, インコーポレイテッド | 遺伝子モザイク症のための方法およびプロセス |
JP6979280B2 (ja) * | 2017-04-11 | 2021-12-08 | 株式会社日本バイオデータ | トランスクリプトームデータの解析方法 |
WO2019028556A1 (en) * | 2017-08-09 | 2019-02-14 | Enrich Bioscience Inc. | METHOD AND SYSTEM FOR ANALYZING DNA METHYLATION AND USE THEREOF FOR DETECTING CANCER |
KR20190034985A (ko) | 2017-09-25 | 2019-04-03 | 삼성전자주식회사 | 인공 신경망의 양자화 방법 및 장치 |
WO2019068760A1 (en) * | 2017-10-05 | 2019-04-11 | Koninklijke Philips N.V. | SYSTEM AND METHOD FOR ENHANCING THE RELIABILITY OF MEDICAL IMAGING DEVICES |
US10146914B1 (en) * | 2018-03-01 | 2018-12-04 | Recursion Pharmaceuticals, Inc. | Systems and methods for evaluating whether perturbations discriminate an on target effect |
US20210130888A1 (en) * | 2018-05-07 | 2021-05-06 | Genemind Biosciences Company Limited | Method, apparatus, and system for detecting chromosome aneuploidy |
JP7485653B2 (ja) | 2018-09-07 | 2024-05-16 | セクエノム, インコーポレイテッド | 移植片拒絶を検出する方法およびシステム |
CN110265087A (zh) * | 2018-10-05 | 2019-09-20 | 中国医药大学附设医院 | 染色体异常检测模型、其检测系统及染色体异常检测方法 |
CN109471053B (zh) * | 2018-10-18 | 2020-01-31 | 电子科技大学 | 一种基于双约束的介电特性迭代成像方法 |
CA3128894A1 (en) | 2019-02-19 | 2020-08-27 | Sequenom, Inc. | Compositions, methods, and systems to detect hematopoietic stem cell transplantation status |
JP2022523564A (ja) | 2019-03-04 | 2022-04-25 | アイオーカレンツ, インコーポレイテッド | 機械学習を使用するデータ圧縮および通信 |
US11551102B2 (en) * | 2019-04-15 | 2023-01-10 | International Business Machines Corporation | Bias detection for unstructured text |
KR20220064952A (ko) * | 2019-06-21 | 2022-05-19 | 쿠퍼서지컬, 인코퍼레이션. | 게놈 배수성을 결정하기 위한 시스템 및 방법(systems and methods for determining genome ploidy) |
US11752700B2 (en) * | 2019-10-01 | 2023-09-12 | Massachusetts Institute Of Technology | Systems and methods for formulating material in a data-driven manner |
JP2022553829A (ja) | 2019-10-31 | 2022-12-26 | セクエノム, インコーポレイテッド | 多胎児妊娠およびパーソナライズされたリスク評価におけるモザイク現象比の適用 |
CN111008356B (zh) * | 2019-11-13 | 2023-06-16 | 成都理工大学 | 一种基于WTSVD算法扣除背景的γ能谱集分析方法 |
CN111145831B (zh) * | 2019-12-31 | 2023-11-24 | 广州市妇女儿童医疗中心 | 构建遗传亚型预测模型的方法、装置和计算机设备 |
CA3173571A1 (en) | 2020-02-28 | 2021-09-02 | Laboratory Corporation Of America Holdings | Compositions, methods, and systems for paternity determination |
CN112582022B (zh) * | 2020-07-21 | 2021-11-23 | 序康医疗科技(苏州)有限公司 | 用于无创胚胎移植优先级评级的系统和方法 |
US20220139498A1 (en) * | 2020-11-04 | 2022-05-05 | Basf Corporation | Apparatuses, systems, and methods for extracting meaning from dna sequence data using natural language processing (nlp) |
CN112749429B (zh) * | 2020-12-01 | 2023-09-01 | 重庆大学 | 一种基于多元插值的海上风电固定式基础结构设计方法 |
CN112464149A (zh) * | 2020-12-15 | 2021-03-09 | 北京百奥智汇科技有限公司 | 数据的概率密度分布的确定方法、装置、设备和介质 |
WO2023244983A1 (en) * | 2022-06-13 | 2023-12-21 | Freenome Holdings, Inc. | Sequence process validation methods and compositions |
CN114841294B (zh) * | 2022-07-04 | 2022-10-28 | 杭州德适生物科技有限公司 | 一种检测染色体结构异常的分类器模型训练方法及装置 |
Family Cites Families (159)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US5720928A (en) | 1988-09-15 | 1998-02-24 | New York University | Image processing and analysis of individual nucleic acid molecules |
US5075212A (en) | 1989-03-27 | 1991-12-24 | University Of Patents, Inc. | Methods of detecting picornaviruses in biological fluids and tissues |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5641628A (en) | 1989-11-13 | 1997-06-24 | Children's Medical Center Corporation | Non-invasive method for isolation and detection of fetal DNA |
SG48759A1 (en) | 1990-01-12 | 2002-07-23 | Abgenix Inc | Generation of xenogenic antibodies |
US5091652A (en) | 1990-01-12 | 1992-02-25 | The Regents Of The University Of California | Laser excited confocal microscope fluorescence scanner and method |
US5432054A (en) | 1994-01-31 | 1995-07-11 | Applied Imaging | Method for separating rare cells from a population of cells |
CA2157219C (en) | 1994-08-31 | 2010-10-05 | Munehiro Noda | Process for purifying recombinant human serum albumin |
US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
EP0799320B1 (en) | 1994-12-23 | 2001-03-07 | Imperial College Of Science, Technology & Medicine | Automated dna sequencing |
US5795782A (en) | 1995-03-17 | 1998-08-18 | President & Fellows Of Harvard College | Characterization of individual polymer molecules based on monomer-interface interactions |
US5670325A (en) | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
IL126544A (en) | 1996-04-25 | 2004-08-31 | Genicon Sciences Inc | Test for component detection using detectable particles in diffused light |
US5786146A (en) | 1996-06-03 | 1998-07-28 | The Johns Hopkins University School Of Medicine | Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids |
US6300077B1 (en) | 1996-08-14 | 2001-10-09 | Exact Sciences Corporation | Methods for the detection of nucleic acids |
US5928870A (en) | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
US6100029A (en) | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
US6403311B1 (en) | 1997-02-12 | 2002-06-11 | Us Genomics | Methods of analyzing polymers using ordered label strategies |
GB9704444D0 (en) | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
US6566101B1 (en) | 1997-06-16 | 2003-05-20 | Anthony P. Shuber | Primer extension methods for detecting nucleic acids |
US6570001B1 (en) | 1997-06-20 | 2003-05-27 | Institut Pasteur | Polynucleotides and their use for detecting resistance to streptogramin A or to streptogramin B and related compounds |
JP2002521064A (ja) | 1998-07-30 | 2002-07-16 | ソレックサ リミテッド | アレイ生体分子およびシークエンシングにおけるその使用 |
US6263286B1 (en) | 1998-08-13 | 2001-07-17 | U.S. Genomics, Inc. | Methods of analyzing polymers using a spatial network of fluorophores and fluorescence resonance energy transfer |
US6818395B1 (en) | 1999-06-28 | 2004-11-16 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences |
US20050287592A1 (en) | 2000-08-29 | 2005-12-29 | Yeda Research And Development Co. Ltd. | Template-dependent nucleic acid polymerization using oligonucleotide triphosphates building blocks |
WO2001023610A2 (en) | 1999-09-29 | 2001-04-05 | Solexa Ltd. | Polynucleotide sequencing |
JP4949585B2 (ja) | 1999-10-29 | 2012-06-13 | アジレント・テクノロジーズ・インク | Dnaポリメラーゼを使用した組成物および方法 |
WO2001062952A1 (en) | 2000-02-24 | 2001-08-30 | Dna Sciences, Inc. | Methods for determining single nucleotide variations |
US6664056B2 (en) | 2000-10-17 | 2003-12-16 | The Chinese University Of Hong Kong | Non-invasive prenatal monitoring |
AU2002239284A1 (en) | 2000-11-27 | 2002-06-03 | The Regents Of The University Of California | Methods and devices for characterizing duplex nucleic acid molecules |
DE10112515B4 (de) | 2001-03-09 | 2004-02-12 | Epigenomics Ag | Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität |
US7297518B2 (en) | 2001-03-12 | 2007-11-20 | California Institute Of Technology | Methods and apparatus for analyzing polynucleotide sequences by asynchronous base extension |
WO2003000920A2 (en) | 2001-06-21 | 2003-01-03 | President And Fellows Of Harvard College | Methods for characterization of nucleic acid molecules |
US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
US20030157489A1 (en) | 2002-01-11 | 2003-08-21 | Michael Wall | Recursive categorical sequence assembly |
US6977162B2 (en) | 2002-03-01 | 2005-12-20 | Ravgen, Inc. | Rapid analysis of variations in a genome |
AU2003220291A1 (en) | 2002-03-15 | 2003-09-29 | Epigenomics Ag | Discovery and diagnostic methods using 5-methylcytosine dna glycosylase |
US20040110208A1 (en) | 2002-03-26 | 2004-06-10 | Selena Chan | Methods and device for DNA sequencing using surface enhanced Raman scattering (SERS) |
US7744816B2 (en) | 2002-05-01 | 2010-06-29 | Intel Corporation | Methods and device for biomolecule characterization |
US20050019784A1 (en) | 2002-05-20 | 2005-01-27 | Xing Su | Method and apparatus for nucleic acid sequencing and identification |
US7005264B2 (en) | 2002-05-20 | 2006-02-28 | Intel Corporation | Method and apparatus for nucleic acid sequencing and identification |
US6952651B2 (en) | 2002-06-17 | 2005-10-04 | Intel Corporation | Methods and apparatus for nucleic acid sequencing by signal stretching and data integration |
CN102344960B (zh) | 2002-09-06 | 2014-06-18 | 波士顿大学信托人 | 基因表达的定量 |
CN1774511B (zh) | 2002-11-27 | 2013-08-21 | 斯昆诺有限公司 | 用于序列变异检测和发现的基于断裂的方法和系统 |
WO2005010145A2 (en) | 2003-07-05 | 2005-02-03 | The Johns Hopkins University | Method and compositions for detection and enumeration of genetic variations |
WO2005017025A2 (en) | 2003-08-15 | 2005-02-24 | The President And Fellows Of Harvard College | Study of polymer molecules and conformations with a nanopore |
EP1664077B1 (en) | 2003-09-05 | 2016-04-13 | Trustees of Boston University | Method for non-invasive prenatal diagnosis |
DE60328193D1 (de) | 2003-10-16 | 2009-08-13 | Sequenom Inc | Nicht invasiver Nachweis fötaler genetischer Merkmale |
US20050095599A1 (en) | 2003-10-30 | 2005-05-05 | Pittaro Richard J. | Detection and identification of biopolymers using fluorescence quenching |
US7169560B2 (en) | 2003-11-12 | 2007-01-30 | Helicos Biosciences Corporation | Short cycle methods for sequencing polynucleotides |
US20050147980A1 (en) | 2003-12-30 | 2005-07-07 | Intel Corporation | Nucleic acid sequencing by Raman monitoring of uptake of nucleotides during molecular replication |
US20100216153A1 (en) * | 2004-02-27 | 2010-08-26 | Helicos Biosciences Corporation | Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities |
US20060046258A1 (en) | 2004-02-27 | 2006-03-02 | Lapidus Stanley N | Applications of single molecule sequencing |
US20100216151A1 (en) | 2004-02-27 | 2010-08-26 | Helicos Biosciences Corporation | Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities |
US7279337B2 (en) | 2004-03-10 | 2007-10-09 | Agilent Technologies, Inc. | Method and apparatus for sequencing polymers through tunneling conductance variation detection |
WO2006028508A2 (en) | 2004-03-23 | 2006-03-16 | President And Fellows Of Harvard College | Methods and apparatus for characterizing polynucleotides |
EP1784754A4 (en) | 2004-08-13 | 2009-05-27 | Harvard College | OPTI-NANOPORE DNA READING PLATFORM WITH ULTRAHOLE THROUGHPUT |
ATE443161T1 (de) | 2004-11-29 | 2009-10-15 | Univ Regensburg Klinikum | Mittel und verfahren für den nachweis von methylierter dna |
ES2398233T3 (es) * | 2005-03-18 | 2013-03-14 | The Chinese University Of Hong Kong | Un método para la detección de aneuploidías cromosómicas |
WO2007065025A2 (en) | 2005-11-29 | 2007-06-07 | Wisconsin Alumni Research Foundation | Method of dna analysis using micro/nanochannel |
PT3002338T (pt) | 2006-02-02 | 2019-08-02 | Univ Leland Stanford Junior | Triagem genética não invasiva de fetos por análise digital |
ATE508209T1 (de) | 2006-02-28 | 2011-05-15 | Univ Louisville Res Found | Erkennung von chromosomabnormalitäten im fötus mit hilfe der tandem-einzelnukleotid- polymorphismen |
WO2007105150A2 (en) | 2006-03-10 | 2007-09-20 | Koninklijke Philips Electronics, N.V. | Methods and systems for identification of dna patterns through spectral analysis |
US20090075252A1 (en) | 2006-04-14 | 2009-03-19 | Helicos Biosciences Corporation | Methods for increasing accuracy of nucleic acid sequencing |
US7282337B1 (en) | 2006-04-14 | 2007-10-16 | Helicos Biosciences Corporation | Methods for increasing accuracy of nucleic acid sequencing |
EP3260556B1 (en) | 2006-05-31 | 2019-07-31 | Sequenom, Inc. | Methods for the extraction of nucleic acid from a sample |
US20080070792A1 (en) | 2006-06-14 | 2008-03-20 | Roland Stoughton | Use of highly parallel snp genotyping for fetal diagnosis |
US8137912B2 (en) | 2006-06-14 | 2012-03-20 | The General Hospital Corporation | Methods for the diagnosis of fetal abnormalities |
JP2009540802A (ja) | 2006-06-16 | 2009-11-26 | セクエノム, インコーポレイテッド | サンプルからの核酸を増幅、検出および定量するための方法および組成物 |
US20080081330A1 (en) | 2006-09-28 | 2008-04-03 | Helicos Biosciences Corporation | Method and devices for analyzing small RNA molecules |
US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
EP1944273A1 (en) | 2007-01-15 | 2008-07-16 | Rockwool International A/S | Process and apparatus for making mineral fibers |
US8003319B2 (en) | 2007-02-02 | 2011-08-23 | International Business Machines Corporation | Systems and methods for controlling position of charged polymer inside nanopore |
EP2610008A1 (en) | 2007-03-28 | 2013-07-03 | BioNano Genomics, Inc. | Methods of macromolecular analysis using nanochannel arrays |
WO2008124107A1 (en) | 2007-04-04 | 2008-10-16 | The Regents Of The University Of California | Compositions, devices, systems, and methods for using a nanopore |
WO2008157264A2 (en) * | 2007-06-15 | 2008-12-24 | Sequenom, Inc. | Combined methods for the detection of chromosomal aneuploidy |
GB0713143D0 (en) | 2007-07-06 | 2007-08-15 | Ucl Business Plc | Nucleic acid detection method |
US20100112590A1 (en) | 2007-07-23 | 2010-05-06 | The Chinese University Of Hong Kong | Diagnosing Fetal Chromosomal Aneuploidy Using Genomic Sequencing With Enrichment |
US9218449B2 (en) | 2007-07-23 | 2015-12-22 | The Chinese University Of Hong Kong | Methods for analyzing massively parallel sequencing data for noninvasive prenatal diagnosis |
SI2183693T2 (sl) * | 2007-07-23 | 2019-02-28 | The Chinese University Of Hong Kong Technology Licenising Office | Diagnosticiranje fetalne kromosomske anevploidije z uporabo genomskega sekvenciranja |
ATE549419T1 (de) | 2007-08-29 | 2012-03-15 | Sequenom Inc | Verfahren und zusammensetzungen für die universelle grössenspezifische polymerasekettenreaktion |
WO2009032779A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for the size-specific seperation of nucleic acid from a sample |
AU2008308457A1 (en) | 2007-10-04 | 2009-04-09 | Halcyon Molecular | Sequencing nucleic acid polymers with electron microscopy |
US7767400B2 (en) | 2008-02-03 | 2010-08-03 | Helicos Biosciences Corporation | Paired-end reads in sequencing by synthesis |
EP2271772B1 (en) | 2008-03-11 | 2014-07-16 | Sequenom, Inc. | Nucleic acid-based tests for prenatal gender determination |
EP2276858A4 (en) | 2008-03-26 | 2011-10-05 | Sequenom Inc | RESTRICTED ENDONUCLEASE AMPLIFIED POLYMORPHIC SEQUENCE DETECTION |
KR20110025993A (ko) | 2008-06-30 | 2011-03-14 | 바이오나노매트릭스, 인크. | 단일-분자 전체 게놈 분석용 장치 및 방법 |
JP2011527191A (ja) | 2008-07-07 | 2011-10-27 | オックスフォード ナノポア テクノロジーズ リミテッド | 塩基検出細孔 |
WO2010004265A1 (en) | 2008-07-07 | 2010-01-14 | Oxford Nanopore Technologies Limited | Enzyme-pore constructs |
JP5727375B2 (ja) | 2008-09-16 | 2015-06-03 | セクエノム, インコーポレイテッド | 非侵襲性の出生前診断のために有用な、母体サンプル由来の胎児核酸のメチル化に基づく濃縮のためのプロセスおよび組成物 |
US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
EP3378951B1 (en) | 2008-09-20 | 2020-05-13 | The Board of Trustees of the Leland Stanford Junior University | Noninvasive diagnosis of aneuploidy by sequencing |
WO2010051318A2 (en) * | 2008-10-31 | 2010-05-06 | Abbott Laboratories | Genomic classification of colorectal cancer based on patterns of gene copy number alterations |
ES2453066T3 (es) | 2008-11-07 | 2014-04-03 | Sequenta, Inc. | Métodos para supervisar las condiciones por análisis de secuencia |
WO2010056728A1 (en) | 2008-11-11 | 2010-05-20 | Helicos Biosciences Corporation | Nucleic acid encoding for multiplex analysis |
JP5846703B2 (ja) | 2008-11-18 | 2016-01-20 | バイオナノ ジェノミックス、インク. | ポリヌクレオチドのマッピング及び配列決定 |
WO2010065470A2 (en) | 2008-12-01 | 2010-06-10 | Consumer Genetics, Inc. | Compositions and methods for detecting background male dna during fetal sex determination |
SG10201501804WA (en) | 2008-12-22 | 2015-05-28 | Celula Inc | Methods and genotyping panels for detecting alleles, genomes, and transcriptomes |
US8455260B2 (en) | 2009-03-27 | 2013-06-04 | Massachusetts Institute Of Technology | Tagged-fragment map assembly |
WO2010115016A2 (en) | 2009-04-03 | 2010-10-07 | Sequenom, Inc. | Nucleic acid preparation compositions and methods |
WO2010138460A1 (en) * | 2009-05-26 | 2010-12-02 | Quest Diagnostics Investments Incorporated | Methods for detecting gene dysregulations |
US8246799B2 (en) | 2009-05-28 | 2012-08-21 | Nabsys, Inc. | Devices and methods for analyzing biomolecules and probes bound thereto |
US20100330557A1 (en) | 2009-06-30 | 2010-12-30 | Zohar Yakhini | Genomic coordinate system |
US8563242B2 (en) * | 2009-08-11 | 2013-10-22 | The Chinese University Of Hong Kong | Method for detecting chromosomal aneuploidy |
CN102666946B (zh) | 2009-09-28 | 2017-09-05 | 生物纳米基因组公司 | 用于聚合物分析的纳米通道阵列和近场照射装置以及相关方法 |
JP2013507964A (ja) | 2009-10-21 | 2013-03-07 | バイオナノ ジェノミックス、インク. | 単一分子全ゲノム解析のための方法及び関連装置 |
CN105779280B (zh) | 2009-11-05 | 2018-09-25 | 香港中文大学 | 由母本生物样品进行胎儿基因组的分析 |
DK2516680T3 (en) | 2009-12-22 | 2016-05-02 | Sequenom Inc | Method and kits to identify aneuploidy |
WO2011090556A1 (en) | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Methods for determining fraction of fetal nucleic acid in maternal samples |
EP2848704B1 (en) | 2010-01-19 | 2018-08-29 | Verinata Health, Inc | Sequencing methods for prenatal diagnoses |
EP2526415B1 (en) | 2010-01-19 | 2017-05-03 | Verinata Health, Inc | Partition defined detection methods |
US9323888B2 (en) * | 2010-01-19 | 2016-04-26 | Verinata Health, Inc. | Detecting and classifying copy number variation |
CA2786564A1 (en) | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Identification of polymorphic sequences in mixtures of genomic dna by whole genome sequencing |
US10388403B2 (en) | 2010-01-19 | 2019-08-20 | Verinata Health, Inc. | Analyzing copy number variation in the detection of cancer |
US20120270739A1 (en) | 2010-01-19 | 2012-10-25 | Verinata Health, Inc. | Method for sample analysis of aneuploidies in maternal samples |
US20110312503A1 (en) | 2010-01-23 | 2011-12-22 | Artemis Health, Inc. | Methods of fetal abnormality detection |
EP2569453B1 (en) | 2010-05-14 | 2015-12-16 | Fluidigm Corporation | Nucleic acid isolation methods |
AU2011255641A1 (en) | 2010-05-18 | 2012-12-06 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
US20120046877A1 (en) | 2010-07-06 | 2012-02-23 | Life Technologies Corporation | Systems and methods to detect copy number variation |
JP2013530727A (ja) | 2010-07-23 | 2013-08-01 | エソテリックス ジェネティック ラボラトリーズ, エルエルシー | 差次的に提示される胎児のゲノム領域もしくは母親のゲノム領域の同定およびそれらの使用 |
EP2656263B1 (en) | 2010-12-22 | 2019-11-06 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
CN103384725A (zh) | 2010-12-23 | 2013-11-06 | 塞昆纳姆股份有限公司 | 胎儿遗传变异的检测 |
US20120190021A1 (en) | 2011-01-25 | 2012-07-26 | Aria Diagnostics, Inc. | Detection of genetic abnormalities |
WO2012108920A1 (en) | 2011-02-09 | 2012-08-16 | Natera, Inc | Methods for non-invasive prenatal ploidy calling |
WO2012118745A1 (en) | 2011-02-28 | 2012-09-07 | Arnold Oliphant | Assay systems for detection of aneuploidy and sex determination |
WO2012141712A1 (en) * | 2011-04-14 | 2012-10-18 | Verinata Health, Inc. | Normalizing chromosomes for the determination and verification of common and rare chromosomal aneuploidies |
GB2484764B (en) | 2011-04-14 | 2012-09-05 | Verinata Health Inc | Normalizing chromosomes for the determination and verification of common and rare chromosomal aneuploidies |
WO2012162884A1 (zh) | 2011-05-31 | 2012-12-06 | 北京贝瑞和康生物技术有限公司 | 检测胚胎或肿瘤染色体拷贝数的试剂盒、装置和方法 |
US20140235474A1 (en) | 2011-06-24 | 2014-08-21 | Sequenom, Inc. | Methods and processes for non invasive assessment of a genetic variation |
JP5659319B2 (ja) | 2011-06-29 | 2015-01-28 | ビージーアイ ヘルス サービス カンパニー リミテッド | 胎児の遺伝的異常の非侵襲的検出 |
US9139874B2 (en) | 2011-07-07 | 2015-09-22 | Life Technologies Corporation | Bi-directional sequencing compositions and methods |
CA2840418C (en) | 2011-07-26 | 2019-10-29 | Verinata Health, Inc. | Method for determining the presence or absence of different aneuploidies in a sample |
US10424394B2 (en) | 2011-10-06 | 2019-09-24 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US20140242588A1 (en) | 2011-10-06 | 2014-08-28 | Sequenom, Inc | Methods and processes for non-invasive assessment of genetic variations |
US9984198B2 (en) | 2011-10-06 | 2018-05-29 | Sequenom, Inc. | Reducing sequence read count error in assessment of complex genetic variations |
US9367663B2 (en) | 2011-10-06 | 2016-06-14 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US10196681B2 (en) | 2011-10-06 | 2019-02-05 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
ES2886508T3 (es) | 2011-10-06 | 2021-12-20 | Sequenom Inc | Métodos y procedimientos para la evaluación no invasiva de variaciones genéticas |
CA2851537C (en) * | 2011-10-11 | 2020-12-29 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US8688388B2 (en) * | 2011-10-11 | 2014-04-01 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
CA2861856C (en) | 2012-01-20 | 2020-06-02 | Sequenom, Inc. | Diagnostic processes that factor experimental conditions |
US9892230B2 (en) | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
DK3663409T3 (da) | 2012-05-21 | 2021-12-13 | Sequenom Inc | Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer |
US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US10497461B2 (en) | 2012-06-22 | 2019-12-03 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
KR102393608B1 (ko) | 2012-09-04 | 2022-05-03 | 가던트 헬쓰, 인크. | 희귀 돌연변이 및 카피수 변이를 검출하기 위한 시스템 및 방법 |
US10482994B2 (en) | 2012-10-04 | 2019-11-19 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
EP2904534B1 (en) | 2012-10-04 | 2021-12-15 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US20130309666A1 (en) | 2013-01-25 | 2013-11-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
FI2981921T3 (fi) | 2013-04-03 | 2023-03-09 | Sequenom Inc | Menetelmiä ja prosesseja geneettisten variaatioiden ei-invasiiviseen arviointiin |
KR102665592B1 (ko) * | 2013-05-24 | 2024-05-21 | 시쿼넘, 인코포레이티드 | 유전적 변이의 비침습 평가를 위한 방법 및 프로세스 |
HUE042654T2 (hu) | 2013-06-21 | 2019-07-29 | Sequenom Inc | Eljárás genetikai variációk nem-invazív megállapítására |
US10174375B2 (en) | 2013-09-20 | 2019-01-08 | The Chinese University Of Hong Kong | Sequencing analysis of circulating DNA to detect and monitor autoimmune diseases |
MY181069A (en) | 2013-10-04 | 2020-12-17 | Sequenom Inc | Methods and processes for non-invasive assessment of genetic variations |
CN111863131A (zh) | 2013-10-07 | 2020-10-30 | 塞昆纳姆股份有限公司 | 用于非侵入性评估染色体改变的方法和过程 |
CA3191504A1 (en) | 2014-05-30 | 2015-12-03 | Sequenom, Inc. | Chromosome representation determinations |
EP3760739A1 (en) | 2014-07-30 | 2021-01-06 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
-
2014
- 2014-10-02 MY MYPI2016000585A patent/MY181069A/en unknown
- 2014-10-02 IL IL295860A patent/IL295860B2/en unknown
- 2014-10-02 ES ES14790884T patent/ES2968644T3/es active Active
- 2014-10-02 KR KR1020237009730A patent/KR20230044325A/ko not_active Application Discontinuation
- 2014-10-02 CN CN201910378737.XA patent/CN110176273B/zh active Active
- 2014-10-02 KR KR1020217042936A patent/KR102514024B1/ko active IP Right Grant
- 2014-10-02 CA CA3205430A patent/CA3205430A1/en active Pending
- 2014-10-02 KR KR1020167012038A patent/KR102384620B1/ko active IP Right Grant
- 2014-10-02 BR BR112016007401-7A patent/BR112016007401B1/pt active IP Right Grant
- 2014-10-02 WO PCT/US2014/058885 patent/WO2015051163A2/en active Application Filing
- 2014-10-02 CA CA2925528A patent/CA2925528C/en active Active
- 2014-10-02 CN CN201480066706.6A patent/CN105814574B/zh active Active
- 2014-10-02 PL PL14790884.2T patent/PL3053071T3/pl unknown
- 2014-10-02 AU AU2014329493A patent/AU2014329493B2/en active Active
- 2014-10-02 EP EP14790884.2A patent/EP3053071B1/en active Active
- 2014-10-02 IL IL304949A patent/IL304949A/en unknown
- 2014-10-02 FI FIEP14790884.2T patent/FI3053071T3/fi active
- 2014-10-02 EP EP23194525.4A patent/EP4258269A3/en active Pending
- 2014-10-02 JP JP2016519380A patent/JP6525434B2/ja active Active
- 2014-10-02 DK DK14790884.2T patent/DK3053071T3/da active
- 2014-10-02 IL IL289974A patent/IL289974B/en unknown
- 2014-10-02 US US14/505,423 patent/US10964409B2/en active Active
-
2016
- 2016-03-24 IL IL244748A patent/IL244748B/en active IP Right Grant
-
2018
- 2018-12-03 JP JP2018226432A patent/JP6854272B2/ja active Active
-
2020
- 2020-09-28 AU AU2020244389A patent/AU2020244389B2/en active Active
- 2020-10-20 IL IL278195A patent/IL278195B/en unknown
- 2020-11-19 US US16/952,847 patent/US20210158898A1/en active Pending
- 2020-12-15 JP JP2020207311A patent/JP7159270B2/ja active Active
-
2022
- 2022-10-12 JP JP2022163930A patent/JP2023002631A/ja active Pending
-
2023
- 2023-02-27 AU AU2023201148A patent/AU2023201148A1/en active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112016007401A2 (pt) | métodos e processos para avaliação não invasiva das variações genéticas | |
CY1121704T1 (el) | Μεθοδος για μη-παρεμβατικη αξιολογηση γενετικων παραλλαγων | |
UY34885A (es) | Proteínas de unión anti-mesotelina | |
CL2015000326S1 (es) | Cargador. | |
DK3532772T3 (da) | Strømforsyningssystem. | |
CL2014003447S1 (es) | Refrigerador. | |
FR3025438B1 (fr) | Regenerateur de catalyseurs. | |
TR201906399T4 (tr) | Kapali döngülü soğutma si̇stemi̇ne sahi̇p elektri̇kli̇ pompa | |
CL2016001202S1 (es) | Neumatico. | |
DK3922128T3 (da) | Transportabelt varmesystem | |
TR201904143T4 (tr) | Silillenmiş poliüretanlar. | |
DK3237407T3 (da) | 3,5-diaminopyrazolkinasehæmmere | |
DK3082007T3 (da) | Trykregulator | |
EA201700060A1 (ru) | Терапевтическое средство для кератоконъюнктивальных расстройств | |
DK2902983T3 (da) | Trådløst system | |
ES1100308Y (es) | Prenda de vestir para bebes. | |
ITUA20161553A1 (it) | Impianto di erogazione del gas. | |
TN2014000384A1 (fr) | نظام صوتي ذكي وآمن | |
TH1601003165A (th) | ลวดเหล็กกล้าสำหรับสลักเกลียว, สลักเกลียว เเละวิธีการสำหรับการผลิตสิ่งเดียวกันนั้น | |
ITUA20161985A1 (it) | Macchina per la realizzazione di balle di potature trasformate in cippato. | |
TN2014000468A1 (fr) | اختراع الة للف شباك مراكب الصيد البحري و تسهيل تحويلها من المركب الى رصيف الميناء ثم ارجاعها للمركب بعد القيام بعملية ترقيعها | |
TN2014000355A1 (fr) | طريقة مبتكرة لتوفير الاضاءة العامة و المنزلية | |
TH1601001433A (th) | วิธีการของและชุดเครื่องสำหรับการเฝ้าสังเกตทรัพยากรที่มีอยู่ของกระบอกสูบก๊าซ | |
TH1401006414B (th) | ชุดกำลัง ยานพาหนะ และวิธีการสำหรับการควบคุมชุดกำลัง | |
CL2015001605S1 (es) | Plancha para cabello. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: A CLASSIFICACAO ANTERIOR ERA: G06F 19/18 Ipc: G16B 20/00 (2006.01), G16B 20/10 (2006.01), G16B 2 |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 02/10/2014, OBSERVADAS AS CONDICOES LEGAIS |