DK3663409T3 - Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer - Google Patents
Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer Download PDFInfo
- Publication number
- DK3663409T3 DK3663409T3 DK19219319.1T DK19219319T DK3663409T3 DK 3663409 T3 DK3663409 T3 DK 3663409T3 DK 19219319 T DK19219319 T DK 19219319T DK 3663409 T3 DK3663409 T3 DK 3663409T3
- Authority
- DK
- Denmark
- Prior art keywords
- processes
- methods
- genetic variations
- invasive assessment
- invasive
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- 230000002068 genetic effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6879—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for sex determination
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/16—Assays for determining copy number or wherein the copy number is of special importance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261649841P | 2012-05-21 | 2012-05-21 | |
US201261740377P | 2012-12-20 | 2012-12-20 | |
US201261740368P | 2012-12-20 | 2012-12-20 | |
US13/782,883 US10504613B2 (en) | 2012-12-20 | 2013-03-01 | Methods and processes for non-invasive assessment of genetic variations |
US13/782,857 US9920361B2 (en) | 2012-05-21 | 2013-03-01 | Methods and compositions for analyzing nucleic acid |
EP13726373.7A EP2852680B1 (en) | 2012-05-21 | 2013-05-20 | Methods and processes for non-invasive assessment of genetic variations |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3663409T3 true DK3663409T3 (da) | 2021-12-13 |
Family
ID=52105674
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13726373.7T DK2852680T3 (da) | 2012-05-21 | 2013-05-20 | Fremgangsmåder og processer til ikke-invasiv evaluering af genetiske variationer |
DK19219319.1T DK3663409T3 (da) | 2012-05-21 | 2013-05-20 | Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13726373.7T DK2852680T3 (da) | 2012-05-21 | 2013-05-20 | Fremgangsmåder og processer til ikke-invasiv evaluering af genetiske variationer |
Country Status (6)
Country | Link |
---|---|
EP (4) | EP4276194A3 (da) |
CA (1) | CA2874195C (da) |
DK (2) | DK2852680T3 (da) |
ES (2) | ES2902401T3 (da) |
HK (1) | HK1205203A1 (da) |
WO (1) | WO2013177086A1 (da) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
US8962247B2 (en) | 2008-09-16 | 2015-02-24 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses |
JP2012525147A (ja) | 2009-04-30 | 2012-10-22 | グッド スタート ジェネティクス, インコーポレイテッド | 遺伝マーカーを評価するための方法および組成物 |
EP3660165B1 (en) | 2009-12-22 | 2023-01-04 | Sequenom, Inc. | Processes and kits for identifying aneuploidy |
US9163281B2 (en) | 2010-12-23 | 2015-10-20 | Good Start Genetics, Inc. | Methods for maintaining the integrity and identification of a nucleic acid template in a multiplex sequencing reaction |
WO2012177792A2 (en) | 2011-06-24 | 2012-12-27 | Sequenom, Inc. | Methods and processes for non-invasive assessment of a genetic variation |
US9367663B2 (en) | 2011-10-06 | 2016-06-14 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US9984198B2 (en) | 2011-10-06 | 2018-05-29 | Sequenom, Inc. | Reducing sequence read count error in assessment of complex genetic variations |
US10196681B2 (en) | 2011-10-06 | 2019-02-05 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US20140242588A1 (en) | 2011-10-06 | 2014-08-28 | Sequenom, Inc | Methods and processes for non-invasive assessment of genetic variations |
US10424394B2 (en) | 2011-10-06 | 2019-09-24 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
AU2013209499B2 (en) | 2012-01-20 | 2018-05-10 | Sequenom, Inc. | Diagnostic processes that factor experimental conditions |
US9605313B2 (en) | 2012-03-02 | 2017-03-28 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US8209130B1 (en) | 2012-04-04 | 2012-06-26 | Good Start Genetics, Inc. | Sequence assembly |
US10504613B2 (en) | 2012-12-20 | 2019-12-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US9920361B2 (en) | 2012-05-21 | 2018-03-20 | Sequenom, Inc. | Methods and compositions for analyzing nucleic acid |
US10497461B2 (en) | 2012-06-22 | 2019-12-03 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
AU2013290102B2 (en) | 2012-07-13 | 2018-11-15 | Sequenom, Inc. | Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
EP2875149B1 (en) * | 2012-07-20 | 2019-12-04 | Verinata Health, Inc. | Detecting and classifying copy number variation in a cancer genome |
US10482994B2 (en) | 2012-10-04 | 2019-11-19 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
CA3120521A1 (en) * | 2012-10-04 | 2014-04-10 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US20130309666A1 (en) | 2013-01-25 | 2013-11-21 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
US10844424B2 (en) | 2013-02-20 | 2020-11-24 | Bionano Genomics, Inc. | Reduction of bias in genomic coverage measurements |
CA2901460A1 (en) | 2013-02-20 | 2014-08-28 | Bionano Genomics, Inc. | Characterization of molecules in nanofluidics |
EP2971100A1 (en) | 2013-03-13 | 2016-01-20 | Sequenom, Inc. | Primers for dna methylation analysis |
US8778609B1 (en) | 2013-03-14 | 2014-07-15 | Good Start Genetics, Inc. | Methods for analyzing nucleic acids |
EP4187543A1 (en) | 2013-04-03 | 2023-05-31 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
IL309903A (en) * | 2013-05-24 | 2024-03-01 | Sequenom Inc | Methods and processes for non-invasive evaluation of genetic variations |
JP6473744B2 (ja) | 2013-06-21 | 2019-02-20 | セクエノム, インコーポレイテッド | 遺伝子の変動の非侵襲的評価のための方法および処理 |
IL304949A (en) | 2013-10-04 | 2023-10-01 | Sequenom Inc | Methods and processes for non-invasive evaluation of genetic variations |
CN105874082B (zh) | 2013-10-07 | 2020-06-02 | 塞昆纳姆股份有限公司 | 用于非侵入性评估染色体改变的方法和过程 |
US10851414B2 (en) | 2013-10-18 | 2020-12-01 | Good Start Genetics, Inc. | Methods for determining carrier status |
CN106164295B (zh) | 2014-02-25 | 2020-08-11 | 生物纳米基因公司 | 减小基因组覆盖测量中的偏差 |
EP3736344A1 (en) | 2014-03-13 | 2020-11-11 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
WO2015175530A1 (en) * | 2014-05-12 | 2015-11-19 | Gore Athurva | Methods for detecting aneuploidy |
WO2015183872A1 (en) | 2014-05-30 | 2015-12-03 | Sequenom, Inc. | Chromosome representation determinations |
KR102441391B1 (ko) * | 2014-07-25 | 2022-09-07 | 유니버시티 오브 워싱톤 | 무세포 dna를 생성하는 조직 및/또는 세포 유형을 결정하는 방법 및 이를 사용하여 질환 또는 장애를 확인하는 방법 |
US20160034640A1 (en) | 2014-07-30 | 2016-02-04 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
WO2016040446A1 (en) | 2014-09-10 | 2016-03-17 | Good Start Genetics, Inc. | Methods for selectively suppressing non-target sequences |
JP2017536087A (ja) | 2014-09-24 | 2017-12-07 | グッド スタート ジェネティクス, インコーポレイテッド | 遺伝子アッセイのロバストネスを増大させるためのプロセス制御 |
EP3204521B1 (en) | 2014-10-10 | 2021-06-02 | Cold Spring Harbor Laboratory | Random nucleotide mutation for nucleotide template counting and assembly |
EP3204512B1 (en) | 2014-10-10 | 2020-05-06 | Sequenom, Inc. | Methods for partitioning of genomic sequences |
US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
WO2016100049A1 (en) | 2014-12-18 | 2016-06-23 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
WO2016112073A1 (en) | 2015-01-06 | 2016-07-14 | Good Start Genetics, Inc. | Screening for structural variants |
WO2017201081A1 (en) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids |
WO2017205826A1 (en) | 2016-05-27 | 2017-11-30 | Sequenom, Inc. | Methods for detecting genetic variations |
WO2018022906A1 (en) | 2016-07-27 | 2018-02-01 | Sequenom, Inc. | Methods for non-invasive assessment of genomic instability |
EP3491560A1 (en) | 2016-07-27 | 2019-06-05 | Sequenom, Inc. | Genetic copy number alteration classifications |
US10329610B2 (en) * | 2016-08-02 | 2019-06-25 | Damoun Nashtaali | Paired-end sequencing method |
US11352662B2 (en) | 2017-01-20 | 2022-06-07 | Sequenom, Inc. | Sequence adapter manufacture and use |
US11929143B2 (en) | 2017-01-20 | 2024-03-12 | Sequenom, Inc | Methods for non-invasive assessment of copy number alterations |
US11929145B2 (en) | 2017-01-20 | 2024-03-12 | Sequenom, Inc | Methods for non-invasive assessment of genetic alterations |
CA3050055C (en) | 2017-01-24 | 2023-09-19 | Sequenom, Inc. | Methods and processes for assessment of genetic variations |
EP3596233B1 (en) | 2017-03-17 | 2022-05-18 | Sequenom, Inc. | Methods and processes for assessment of genetic mosaicism |
CN110373458B (zh) * | 2019-06-27 | 2020-05-19 | 东莞博奥木华基因科技有限公司 | 一种地中海贫血检测的试剂盒及分析系统 |
CA3159786A1 (en) | 2019-10-31 | 2021-05-06 | Sequenom, Inc. | Application of mosaicism ratio in multifetal gestations and personalized risk assessment |
WO2021121368A1 (en) * | 2019-12-18 | 2021-06-24 | The Chinese University Of Hong Kong | Cell-free dna fragmentation and nucleases |
WO2022119812A1 (en) | 2020-12-02 | 2022-06-09 | Illumina Software, Inc. | System and method for detection of genetic alterations |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5720928A (en) | 1988-09-15 | 1998-02-24 | New York University | Image processing and analysis of individual nucleic acid molecules |
US6927028B2 (en) | 2001-08-31 | 2005-08-09 | Chinese University Of Hong Kong | Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA |
CN1703521B (zh) | 2002-09-06 | 2011-11-16 | 波士顿大学信托人 | 基因表达的定量 |
EP1613723B1 (en) | 2002-11-27 | 2013-05-15 | Sequenom, Inc. | Fragmentation-based methods for sequence variation detection and discovery |
CA2531105C (en) | 2003-07-05 | 2015-03-17 | The Johns Hopkins University | Method and compositions for detection and enumeration of genetic variations |
ATE443161T1 (de) | 2004-11-29 | 2009-10-15 | Univ Regensburg Klinikum | Mittel und verfahren für den nachweis von methylierter dna |
WO2007140417A2 (en) | 2006-05-31 | 2007-12-06 | Sequenom, Inc. | Methods and compositions for the extraction and amplification of nucleic acid from a sample |
AU2007260750A1 (en) | 2006-06-16 | 2007-12-21 | Sequenom, Inc. | Methods and compositions for the amplification, detection and quantification of nucleic acid from a sample |
KR20230117256A (ko) | 2007-07-23 | 2023-08-07 | 더 차이니즈 유니버시티 오브 홍콩 | 대규모 병렬 게놈 서열분석을 이용한 태아 염색체 이수성의진단 방법 |
WO2009032779A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for the size-specific seperation of nucleic acid from a sample |
WO2009032781A2 (en) | 2007-08-29 | 2009-03-12 | Sequenom, Inc. | Methods and compositions for universal size-specific polymerase chain reaction |
CA2718137A1 (en) | 2008-03-26 | 2009-10-01 | Sequenom, Inc. | Restriction endonuclease enhanced polymorphic sequence detection |
EP3103871B1 (en) | 2008-09-16 | 2020-07-29 | Sequenom, Inc. | Processes for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for fetal nucleic acid quantification |
US8476013B2 (en) | 2008-09-16 | 2013-07-02 | Sequenom, Inc. | Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses |
WO2010065470A2 (en) * | 2008-12-01 | 2010-06-10 | Consumer Genetics, Inc. | Compositions and methods for detecting background male dna during fetal sex determination |
EP3211095B1 (en) | 2009-04-03 | 2019-01-02 | Sequenom, Inc. | Nucleic acid preparation compositions and methods |
WO2011091063A1 (en) * | 2010-01-19 | 2011-07-28 | Verinata Health, Inc. | Partition defined detection methods |
AU2010343276B2 (en) | 2010-01-19 | 2015-05-28 | Verinata Health, Inc. | Methods for determining fraction of fetal nucleic acid in maternal samples |
US20140227691A1 (en) | 2010-05-14 | 2014-08-14 | Fluidigm, Inc. | Nucleic acid isolation methods |
US20120219950A1 (en) * | 2011-02-28 | 2012-08-30 | Arnold Oliphant | Assay systems for detection of aneuploidy and sex determination |
WO2013019361A1 (en) | 2011-07-07 | 2013-02-07 | Life Technologies Corporation | Sequencing methods |
DK2764459T3 (da) * | 2011-10-06 | 2021-08-23 | Sequenom Inc | Fremgangsmåder og processer til ikke-invasiv bedømmelse af genetiske variationer |
US9367663B2 (en) | 2011-10-06 | 2016-06-14 | Sequenom, Inc. | Methods and processes for non-invasive assessment of genetic variations |
DK2766496T3 (da) * | 2011-10-11 | 2017-05-15 | Sequenom Inc | Fremgangsmåder og processer for ikke-invasiv vurdering af genetiske variationer |
US9892230B2 (en) * | 2012-03-08 | 2018-02-13 | The Chinese University Of Hong Kong | Size-based analysis of fetal or tumor DNA fraction in plasma |
-
2013
- 2013-05-20 WO PCT/US2013/041906 patent/WO2013177086A1/en active Application Filing
- 2013-05-20 DK DK13726373.7T patent/DK2852680T3/da active
- 2013-05-20 EP EP23193976.0A patent/EP4276194A3/en active Pending
- 2013-05-20 ES ES19219319T patent/ES2902401T3/es active Active
- 2013-05-20 CA CA2874195A patent/CA2874195C/en active Active
- 2013-05-20 EP EP13726373.7A patent/EP2852680B1/en active Active
- 2013-05-20 EP EP19219319.1A patent/EP3663409B1/en active Active
- 2013-05-20 EP EP21201053.2A patent/EP3978621B1/en active Active
- 2013-05-20 ES ES13726373T patent/ES2772029T3/es active Active
- 2013-05-20 DK DK19219319.1T patent/DK3663409T3/da active
-
2015
- 2015-06-16 HK HK15105735.2A patent/HK1205203A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2874195C (en) | 2020-08-25 |
CA2874195A1 (en) | 2013-11-28 |
EP2852680A1 (en) | 2015-04-01 |
EP3978621A1 (en) | 2022-04-06 |
ES2772029T3 (es) | 2020-07-07 |
EP2852680B1 (en) | 2019-12-25 |
EP4276194A2 (en) | 2023-11-15 |
EP3663409B1 (en) | 2021-10-06 |
WO2013177086A1 (en) | 2013-11-28 |
EP3663409A1 (en) | 2020-06-10 |
EP3978621B1 (en) | 2023-08-30 |
EP4276194A3 (en) | 2024-03-06 |
DK2852680T3 (da) | 2020-03-16 |
HK1205203A1 (en) | 2015-12-11 |
ES2902401T3 (es) | 2022-03-28 |
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