BR112015023886B1 - Polipeptídeo e composição farmacêutica - Google Patents

Polipeptídeo e composição farmacêutica Download PDF

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Publication number
BR112015023886B1
BR112015023886B1 BR112015023886-6A BR112015023886A BR112015023886B1 BR 112015023886 B1 BR112015023886 B1 BR 112015023886B1 BR 112015023886 A BR112015023886 A BR 112015023886A BR 112015023886 B1 BR112015023886 B1 BR 112015023886B1
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BR
Brazil
Prior art keywords
amino acid
acid sequence
polypeptide
momp
subsequence
Prior art date
Application number
BR112015023886-6A
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English (en)
Portuguese (pt)
Other versions
BR112015023886A2 (pt
Inventor
Frank Follmann
Ida Rosenkrands
Anja Olsen
Peter Lawætz Andersen
Original Assignee
Statens Serum Institut
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Publication date
Application filed by Statens Serum Institut filed Critical Statens Serum Institut
Publication of BR112015023886A2 publication Critical patent/BR112015023886A2/pt
Publication of BR112015023886B1 publication Critical patent/BR112015023886B1/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/118Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
BR112015023886-6A 2013-03-18 2014-03-17 Polipeptídeo e composição farmacêutica BR112015023886B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201300155 2013-03-18
DKPA201300155 2013-03-18
DKPA201300684 2013-12-11
DKPA201300684 2013-12-11
PCT/DK2014/000015 WO2014146663A1 (en) 2013-03-18 2014-03-17 Vaccines against chlamydia sp.

Publications (2)

Publication Number Publication Date
BR112015023886A2 BR112015023886A2 (pt) 2017-10-24
BR112015023886B1 true BR112015023886B1 (pt) 2023-05-16

Family

ID=50639248

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015023886-6A BR112015023886B1 (pt) 2013-03-18 2014-03-17 Polipeptídeo e composição farmacêutica

Country Status (20)

Country Link
US (4) US20140275478A1 (https=)
EP (1) EP2976355B1 (https=)
JP (3) JP2016514713A (https=)
CN (2) CN113185587A (https=)
AU (1) AU2014234765B2 (https=)
BR (1) BR112015023886B1 (https=)
CA (1) CA2907199C (https=)
CY (1) CY1122905T1 (https=)
DK (1) DK2976355T3 (https=)
ES (1) ES2781579T3 (https=)
HR (1) HRP20200511T1 (https=)
HU (1) HUE048573T2 (https=)
LT (1) LT2976355T (https=)
PL (1) PL2976355T3 (https=)
PT (1) PT2976355T (https=)
RS (1) RS60135B1 (https=)
RU (1) RU2723046C2 (https=)
SI (1) SI2976355T1 (https=)
SM (1) SMT202000160T1 (https=)
WO (1) WO2014146663A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10688171B2 (en) 2015-02-10 2020-06-23 Ohio State Innovation Foundation Chlamydia-activated B cell platforms and methods thereof
CN104800841B (zh) * 2015-03-02 2019-04-02 中国农业科学院兰州兽医研究所 牦牛流产衣原体灭活疫苗及其制备方法
CA2980227A1 (en) 2015-03-24 2016-09-29 Universiteit Gent A method for the detection of chlamydia suis
AU2016349937B2 (en) * 2015-11-04 2021-09-30 University Of The Sunshine Coast Chlamydia antigens and uses thereof
CA3004924A1 (en) 2015-11-10 2017-05-18 Ohio State Innovation Foundation Methods and compositions related to accelerated humoral affinity
NL2019320B1 (en) * 2017-03-02 2018-09-21 Biosparq B V Diagnostic method and system for diagnosis
JP2020513836A (ja) * 2017-03-23 2020-05-21 オハイオ・ステイト・イノベーション・ファウンデーション 組換えクラミジア活性化b細胞プラットフォーム及びその使用方法
RU2721123C1 (ru) * 2019-09-26 2020-05-18 федеральное государственное бюджетное учреждение «Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения Российской Федерации Штамм рекомбинантной псевдоаденовирусной частицы, экспрессирующий химерный ген MBL-CT666 Chlamydia trachomatis, способ его получения, иммуногенная композиция для защиты от урогенитального хламидиоза человека
EP4267176A1 (en) * 2020-12-23 2023-11-01 INSERM (Institut National de la Santé et de la Recherche Médicale) Chlamydia vaccine based on targeting momp vs4 antigen to antigen presenting cells
CN116854812B (zh) * 2022-03-23 2024-09-24 东莞市朋志生物科技有限公司 抗沙眼衣原体的抗体、检测沙眼衣原体的试剂和试剂盒
CN115975049A (zh) * 2022-11-12 2023-04-18 北京成大天和生物科技有限公司 一种沙眼衣原体重组蛋白及其制备方法和应用
CN120813371A (zh) * 2023-03-02 2025-10-17 赛诺菲巴斯德有限公司 用于在衣原体病的治疗中使用的组合物
WO2025104023A1 (en) 2023-11-13 2025-05-22 Ziphius Nv MODIFIED ALPHAVIRAL nsP3

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599230A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4599231A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US4608251A (en) 1984-11-09 1986-08-26 Pitman-Moore, Inc. LHRH analogues useful in stimulating anti-LHRH antibodies and vaccines containing such analogues
US4601903A (en) 1985-05-01 1986-07-22 The United States Of America As Represented By The Department Of Health And Human Services Vaccine against Neisseria meningitidis Group B serotype 2 invasive disease
US5869608A (en) 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
US5837268A (en) * 1991-10-16 1998-11-17 University Of Saskatchewan GnRH-leukotoxin chimeras
GB9215780D0 (en) * 1992-07-24 1992-09-09 Univ London Pharmacy Peptide compounds
ATE174628T1 (de) * 1992-07-31 1999-01-15 Medeva Holdings Bv Expression rekombinanter fusionsproteine in attenuierten bakterien
EP0662083A1 (en) 1992-09-18 1995-07-12 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Synthetic peptide vaccine for chlamydia trachomatis
GB9516293D0 (en) * 1995-08-09 1995-10-11 Immunova Ltee Novel peptides and their use as vaccines
JP2002512622A (ja) * 1997-05-06 2002-04-23 バンダービルト ユニバーシティー クラミジアにより引き起こされる感染の診断および管理のための抗クラミジア剤の組成物
US7651857B2 (en) * 2000-12-22 2010-01-26 The Mathilda And Terence Kennedy Institute Of Rheumatology Trust Methods for enhancing antigen presentation
US7105171B2 (en) 2002-03-07 2006-09-12 The Regents Of The University Of California Porin B (PorB) as a therapeutic target for prevention and treatment of infection by Chlamydia
MXPA05013260A (es) * 2003-06-26 2006-03-09 Chiron Corp Composiciones inmunogenicas para chlamydia trachomatis.
WO2006045308A2 (en) * 2004-10-25 2006-05-04 Statens Serum Institut Chlamydia trachomatis antigens for vaccine and diagnostic use
US7964200B2 (en) * 2005-05-18 2011-06-21 Children's Hospital & Research Center At Oakland Methods and compositions for immunizing against Chlamydia infection
TW201012929A (en) * 2008-09-29 2010-04-01 Univ Nat Pingtung Sci & Tech A hybridoma cell line producing monoclonal antibodies against chalmydophila aborts
EP2413959A4 (en) * 2009-01-29 2013-06-19 British Columbia Cancer Agency CHLAMYDIA-ANTIGENE COMPREHENSIVE COMPOSITIONS
CN103068837B (zh) * 2010-05-28 2015-06-24 斯匹遐生物技术公司 嵌合momp抗原、方法和使用
EP2729158B1 (en) * 2011-06-17 2018-01-24 Universiteit Gent Vaccines for chlamydia

Also Published As

Publication number Publication date
US20250255951A1 (en) 2025-08-14
SI2976355T1 (sl) 2020-07-31
RU2015141214A (ru) 2017-04-26
JP7506930B2 (ja) 2024-06-27
PT2976355T (pt) 2020-04-02
BR112015023886A2 (pt) 2017-10-24
CY1122905T1 (el) 2021-10-29
US20140275478A1 (en) 2014-09-18
HRP20200511T1 (hr) 2020-06-26
ES2781579T3 (es) 2020-09-03
RU2723046C2 (ru) 2020-06-08
LT2976355T (lt) 2020-04-10
JP2021193123A (ja) 2021-12-23
US10925954B2 (en) 2021-02-23
DK2976355T3 (en) 2020-03-30
AU2014234765A1 (en) 2015-10-08
RS60135B1 (sr) 2020-05-29
US20190099478A1 (en) 2019-04-04
JP2019163253A (ja) 2019-09-26
HUE048573T2 (hu) 2020-08-28
JP2016514713A (ja) 2016-05-23
EP2976355B1 (en) 2020-01-01
CN105377879B (zh) 2021-05-04
JP7510142B2 (ja) 2024-07-03
US20210205433A1 (en) 2021-07-08
CA2907199A1 (en) 2014-09-25
SMT202000160T1 (it) 2020-05-08
PL2976355T3 (pl) 2020-07-13
EP2976355A1 (en) 2016-01-27
CN113185587A (zh) 2021-07-30
AU2014234765B2 (en) 2018-01-25
WO2014146663A1 (en) 2014-09-25
CA2907199C (en) 2023-10-17
CN105377879A (zh) 2016-03-02

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 17/03/2014, OBSERVADAS AS CONDICOES LEGAIS