BR112015022454A2 - método para a produção de bacterioclorofila a - Google Patents
método para a produção de bacterioclorofila aInfo
- Publication number
- BR112015022454A2 BR112015022454A2 BR112015022454A BR112015022454A BR112015022454A2 BR 112015022454 A2 BR112015022454 A2 BR 112015022454A2 BR 112015022454 A BR112015022454 A BR 112015022454A BR 112015022454 A BR112015022454 A BR 112015022454A BR 112015022454 A2 BR112015022454 A2 BR 112015022454A2
- Authority
- BR
- Brazil
- Prior art keywords
- fermentation
- bacteriochlorophyll
- source
- bchla
- production
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 108010003118 Bacteriochlorophylls Proteins 0.000 title 1
- DSJXIQQMORJERS-AGGZHOMASA-M bacteriochlorophyll a Chemical compound C1([C@@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC([C@H](CC)[C@H]3C)=[N+]4C3=CC3=C(C(C)=O)C(C)=C5N3[Mg-2]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 DSJXIQQMORJERS-AGGZHOMASA-M 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 4
- 238000000855 fermentation Methods 0.000 abstract 4
- 230000004151 fermentation Effects 0.000 abstract 4
- 108010070075 Bacteriochlorophyll A Proteins 0.000 abstract 2
- ZSERVQBSOBTXFV-DHHJBRQQSA-M bacteriochlorophyll a Chemical compound C1([C@H](C(=O)OC)C(=O)C2=C3C)=C2N2C3=CC([C@@H](CC)[C@@H]3C)=[N+]4C3=CC3=C(C(C)=O)C(C)=C5N3[Mg]42[N+]2=C1[C@@H](CCC(=O)OC\C=C(/C)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)[C@H](C)C2=C5 ZSERVQBSOBTXFV-DHHJBRQQSA-M 0.000 abstract 2
- 229910010272 inorganic material Inorganic materials 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
- 241001495152 Rhodovulum sulfidophilum Species 0.000 abstract 1
- LXRROUCWANUVLT-UHFFFAOYSA-J [C+4].[O-]C(=O)CCC([O-])=O.[O-]C(=O)CCC([O-])=O Chemical compound [C+4].[O-]C(=O)CCC([O-])=O.[O-]C(=O)CCC([O-])=O LXRROUCWANUVLT-UHFFFAOYSA-J 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 150000002484 inorganic compounds Chemical class 0.000 abstract 1
- 239000002609 medium Substances 0.000 abstract 1
- 229910017464 nitrogen compound Inorganic materials 0.000 abstract 1
- -1 nitrogen compound inorganic compound Chemical class 0.000 abstract 1
- 229910052698 phosphorus Inorganic materials 0.000 abstract 1
- 239000011574 phosphorus Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/16—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing two or more hetero rings
- C12P17/165—Heterorings having nitrogen atoms as the only ring heteroatoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
resumo método para a produção de bacterioclorofila a a presente invenção se refere a um método de fermentação de alimentação por lote para a produção de bacterioclorofila a (bchla) a partir de rhodovulum sulfidophilum, em que o meio de desenvolvimento contém um composto de nitrogênio inorgânico como a fonte de nitrogênio e durante a fermentação o meio de desenvolvimento é suplementado com uma fonte de carbono succinato, uma fonte de nitrogênio de composto inorgânico e uma fonte de fósforo a partir de reservatórios externos conectados ao recipiente de fermentação, e após a conclusão da fermentação bchla é recuperada a partir das células separadas. 1/1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361776314P | 2013-03-11 | 2013-03-11 | |
| US61/776,314 | 2013-03-11 | ||
| PCT/IB2014/000468 WO2014140786A1 (en) | 2013-03-11 | 2014-03-11 | Method for producing bacteriochlorophyll a |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015022454A2 true BR112015022454A2 (pt) | 2017-07-18 |
| BR112015022454B1 BR112015022454B1 (pt) | 2021-09-08 |
Family
ID=50543252
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015022454-7A BR112015022454B1 (pt) | 2013-03-11 | 2014-03-11 | Método de fermentação em batelada alimentada para a produção de bacterioclorofila a a partir de rhodovulum sulfidophilum |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10087474B2 (pt) |
| EP (1) | EP2971026B1 (pt) |
| JP (1) | JP6517158B2 (pt) |
| CN (1) | CN105358702B (pt) |
| AU (1) | AU2014229637B2 (pt) |
| BR (1) | BR112015022454B1 (pt) |
| CA (1) | CA2905109C (pt) |
| DK (1) | DK2971026T3 (pt) |
| ES (1) | ES2849427T3 (pt) |
| HK (1) | HK1220231A1 (pt) |
| HU (1) | HUE053222T2 (pt) |
| IL (1) | IL241480B (pt) |
| MX (1) | MX360151B (pt) |
| PL (1) | PL2971026T3 (pt) |
| PT (1) | PT2971026T (pt) |
| RU (1) | RU2671158C2 (pt) |
| WO (1) | WO2014140786A1 (pt) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20210198315A1 (en) * | 2016-02-01 | 2021-07-01 | Naurex, INC | Process for synthesis of peptide compounds |
| GB2581999B (en) | 2019-03-07 | 2023-01-04 | Bpr Medical Ltd | Gas flow alarm |
| CN113832082A (zh) * | 2021-11-11 | 2021-12-24 | 天津科技大学 | 一种快速分离纯化光合细菌的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61192297A (ja) * | 1985-02-19 | 1986-08-26 | Mitsubishi Gas Chem Co Inc | バクテリオクロロフイルの製造法 |
| US6147195A (en) | 1993-07-26 | 2000-11-14 | Yeda Research And Development Co., Ltd. | Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them |
| IL116126A0 (en) | 1995-11-24 | 1996-01-31 | Yeda Res & Dev | Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them |
| RU2144085C1 (ru) * | 1996-07-12 | 2000-01-10 | Московская государственная академия тонкой химической технологии им.М.В.Ломоносова | Способ получения бактериохлорофилла а |
| US5935808A (en) * | 1997-07-29 | 1999-08-10 | Yissum Research And Development Company Of The Hebrew University Of Jerusalem | Carotenoid-producing bacterial species and process for production of carotenoids using same |
| EP1137411B1 (en) | 1998-12-09 | 2006-12-06 | YEDA RESEARCH AND DEVELOPMENT Co. LTD. | Palladium-substituted bacteriochlorophyll derivatives and use thereof |
| IL152900A0 (en) | 2002-11-17 | 2003-06-24 | Yeda Res & Dev | Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses |
| KR101191700B1 (ko) | 2004-06-07 | 2012-10-16 | 예다 리서치 앤드 디벨럽먼트 캄파니 리미티드 | 양이온성 박테리오클로로필 유도체 및 이의 용도 |
| JP5101894B2 (ja) * | 2007-01-15 | 2012-12-19 | サントリーホールディングス株式会社 | 高度不飽和脂肪酸及びこれを含有する脂質の製造方法 |
-
2014
- 2014-03-11 DK DK14718737.1T patent/DK2971026T3/da active
- 2014-03-11 EP EP14718737.1A patent/EP2971026B1/en active Active
- 2014-03-11 PT PT147187371T patent/PT2971026T/pt unknown
- 2014-03-11 CN CN201480026085.9A patent/CN105358702B/zh active Active
- 2014-03-11 JP JP2015562365A patent/JP6517158B2/ja active Active
- 2014-03-11 WO PCT/IB2014/000468 patent/WO2014140786A1/en active Application Filing
- 2014-03-11 US US14/774,665 patent/US10087474B2/en active Active
- 2014-03-11 HU HUE14718737A patent/HUE053222T2/hu unknown
- 2014-03-11 PL PL14718737T patent/PL2971026T3/pl unknown
- 2014-03-11 AU AU2014229637A patent/AU2014229637B2/en not_active Ceased
- 2014-03-11 CA CA2905109A patent/CA2905109C/en not_active Expired - Fee Related
- 2014-03-11 MX MX2015012331A patent/MX360151B/es active IP Right Grant
- 2014-03-11 BR BR112015022454-7A patent/BR112015022454B1/pt not_active IP Right Cessation
- 2014-03-11 ES ES14718737T patent/ES2849427T3/es active Active
- 2014-03-11 RU RU2015142886A patent/RU2671158C2/ru active
-
2015
- 2015-09-10 IL IL241480A patent/IL241480B/en active IP Right Grant
-
2016
- 2016-07-13 HK HK16108213.6A patent/HK1220231A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2016509860A (ja) | 2016-04-04 |
| IL241480B (en) | 2020-01-30 |
| US10087474B2 (en) | 2018-10-02 |
| MX2015012331A (es) | 2016-05-31 |
| CA2905109A1 (en) | 2014-09-18 |
| RU2671158C2 (ru) | 2018-10-29 |
| HUE053222T2 (hu) | 2021-06-28 |
| PL2971026T3 (pl) | 2021-06-14 |
| BR112015022454B1 (pt) | 2021-09-08 |
| EP2971026A1 (en) | 2016-01-20 |
| ES2849427T3 (es) | 2021-08-18 |
| JP6517158B2 (ja) | 2019-05-22 |
| US20160024542A1 (en) | 2016-01-28 |
| AU2014229637B2 (en) | 2017-05-04 |
| IL241480A0 (en) | 2015-11-30 |
| RU2015142886A (ru) | 2017-04-17 |
| DK2971026T3 (da) | 2021-02-15 |
| EP2971026B1 (en) | 2020-11-18 |
| CN105358702A (zh) | 2016-02-24 |
| CN105358702B (zh) | 2020-12-29 |
| HK1220231A1 (zh) | 2017-04-28 |
| PT2971026T (pt) | 2021-02-09 |
| WO2014140786A1 (en) | 2014-09-18 |
| MX360151B (es) | 2018-10-24 |
| AU2014229637A1 (en) | 2015-11-05 |
| CA2905109C (en) | 2021-03-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 11/03/2014, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 9A ANUIDADE. |
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| B24D | Patent annual fee: restoration after fee payment |