BR112015013234B1 - Método para amplificação multiplex de sonda dependente de ligação - Google Patents
Método para amplificação multiplex de sonda dependente de ligação Download PDFInfo
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| IL285521B2 (en) | 2013-08-19 | 2023-03-01 | Singular Bio Inc | Methods for single molecule detection |
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| CN113528623A (zh) * | 2015-02-18 | 2021-10-22 | 卓异生物公司 | 用于单分子检测的测定及其应用 |
| CN107083427B (zh) * | 2016-04-01 | 2021-07-30 | 广州市基准医疗有限责任公司 | Dna连接酶介导的dna扩增技术 |
| WO2017181161A1 (en) * | 2016-04-15 | 2017-10-19 | Predicine, Inc. | Systems and methods for detecting genetic alterations |
| US11174503B2 (en) | 2016-09-21 | 2021-11-16 | Predicine, Inc. | Systems and methods for combined detection of genetic alterations |
| US11268137B2 (en) | 2016-12-09 | 2022-03-08 | Boreal Genomics, Inc. | Linked ligation |
| EP3565906B1 (en) * | 2017-01-05 | 2021-01-27 | Tervisetehnoloogiate Arenduskeskus AS | Quantifying dna sequences |
| US20180237853A1 (en) * | 2017-02-19 | 2018-08-23 | Yan Wang | Methods, Compositions and Kits for Detection of Mutant Variants of Target Genes |
| CN107177693B (zh) * | 2017-07-19 | 2020-11-06 | 中山大学 | 一种多倍pcr扩增方法 |
| WO2019046768A1 (en) * | 2017-08-31 | 2019-03-07 | William Marsh Rice University | SYMBOLIC SEQUENCING OF DNA AND RNA BY SEQUENCE CODING |
| CN110656159B (zh) * | 2018-06-28 | 2024-01-09 | 深圳华大生命科学研究院 | 一种拷贝数变异的检测方法 |
| JP7361774B2 (ja) * | 2018-07-27 | 2023-10-16 | ミリアド・ウィメンズ・ヘルス・インコーポレーテッド | シーケンスリードの独立したアラインメントおよびペアリングによって高度に相同なシーケンスにおける遺伝的変異を検出するための方法 |
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| AU2019375136B2 (en) * | 2018-11-05 | 2025-10-16 | Centre Henri Becquerel | Method for diagnosing a cancer and associated kit |
| CN115786455A (zh) * | 2022-07-12 | 2023-03-14 | 江阴检汇生物科技有限公司 | 一种基于mlpa-ngs方法用于司法鉴定的snp位点检测组合物及其应用 |
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| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5508179A (en) | 1994-03-18 | 1996-04-16 | Bio-Rad Laboratories, Inc. | Use of deoxyribose nicotinamide adenine dinucleotide to enhance the specificity of NAD+ -dependent ligation reactions |
| EP2369007B1 (en) * | 1996-05-29 | 2015-07-29 | Cornell Research Foundation, Inc. | Detection of nucleic acid sequence differences using coupled ligase detection and polymerase chain reactions |
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| EP1991698B1 (en) * | 2006-03-01 | 2013-12-18 | Keygene N.V. | High throughput sequence-based detection of snps using ligation assays |
| US8852864B2 (en) * | 2008-01-17 | 2014-10-07 | Sequenom Inc. | Methods and compositions for the analysis of nucleic acids |
| CA2757300C (en) * | 2009-04-01 | 2018-01-09 | Dxterity Diagnostics Incorporated | Chemical ligation dependent probe amplification (clpa) |
| CN102648295B (zh) * | 2009-12-07 | 2017-08-08 | 伊鲁米那股份有限公司 | 用于多重基因分型的多样品索引 |
| EP2526207A4 (en) * | 2010-01-22 | 2013-10-09 | Univ California | COMPOSITIONS AND METHODS FOR CHEMICAL SCREENING AT SIGNATURE BASE |
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| US9745616B2 (en) * | 2011-05-17 | 2017-08-29 | Dxterity Diagnostics Incorporated | Methods and compositions for detecting target nucleic acids |
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| CA2894381C (en) | 2021-01-12 |
| CL2015001568A1 (es) | 2016-08-26 |
| BR112015013234A2 (pt) | 2018-02-06 |
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