BR112015010570B8 - agentes microbianos, composto e seu uso e composição farmacêutica - Google Patents

agentes microbianos, composto e seu uso e composição farmacêutica

Info

Publication number
BR112015010570B8
BR112015010570B8 BR112015010570A BR112015010570A BR112015010570B8 BR 112015010570 B8 BR112015010570 B8 BR 112015010570B8 BR 112015010570 A BR112015010570 A BR 112015010570A BR 112015010570 A BR112015010570 A BR 112015010570A BR 112015010570 B8 BR112015010570 B8 BR 112015010570B8
Authority
BR
Brazil
Prior art keywords
compost
pharmaceutical composition
microbial agents
compounds
salts
Prior art date
Application number
BR112015010570A
Other languages
English (en)
Other versions
BR112015010570A2 (pt
BR112015010570B1 (pt
Inventor
Parhi Ajit
S Pilch Daniel
J Lavoie Edmond
Kaul Malvika
Zhang Yongzheng
Original Assignee
Univ Rutgers
Taxis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Rutgers, Taxis Pharmaceuticals Inc filed Critical Univ Rutgers
Publication of BR112015010570A2 publication Critical patent/BR112015010570A2/pt
Publication of BR112015010570B1 publication Critical patent/BR112015010570B1/pt
Publication of BR112015010570B8 publication Critical patent/BR112015010570B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/88—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having the nitrogen atom of at least one of the carboxamide groups further acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/64—Benzothiazoles with only hydrocarbon or substituted hydrocarbon radicals attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epidemiology (AREA)

Abstract

agentes antimicrobianos a invenção fornece compostos de fórmula (i): (i) em que r1-r3, n e w têm qualquer um dos valores definidos no relatório descritivo e sais do mesmo. os compostos têm boa solubilidade e são úteis para tratar infecções bacterianas.
BR112015010570A 2012-11-08 2013-11-08 agentes microbianos, composto e seu uso e composição farmacêutica BR112015010570B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261724182P 2012-11-08 2012-11-08
PCT/US2013/069316 WO2014074932A1 (en) 2012-11-08 2013-11-08 Antimicrobial agents

Publications (3)

Publication Number Publication Date
BR112015010570A2 BR112015010570A2 (pt) 2017-07-11
BR112015010570B1 BR112015010570B1 (pt) 2020-03-17
BR112015010570B8 true BR112015010570B8 (pt) 2021-04-20

Family

ID=49622917

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015010570A BR112015010570B8 (pt) 2012-11-08 2013-11-08 agentes microbianos, composto e seu uso e composição farmacêutica

Country Status (17)

Country Link
US (2) US20150307517A1 (pt)
EP (1) EP2917212B1 (pt)
JP (1) JP6411355B2 (pt)
KR (1) KR102163608B1 (pt)
CN (1) CN104981469B (pt)
AU (1) AU2013342095B2 (pt)
BR (1) BR112015010570B8 (pt)
CA (1) CA2891092C (pt)
DK (1) DK2917212T3 (pt)
ES (1) ES2748665T3 (pt)
HK (1) HK1215031A1 (pt)
IL (1) IL238677B (pt)
MX (1) MX364443B (pt)
PL (1) PL2917212T3 (pt)
SG (1) SG11201503620RA (pt)
WO (1) WO2014074932A1 (pt)
ZA (1) ZA201503372B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2828245A1 (en) * 2012-03-21 2015-01-28 Rutgers, The State University of New Jersey Antimicrobial agents
US9458150B2 (en) 2013-11-08 2016-10-04 Rutgers, The State University Of New Jersey Antimicrobial agents
US20170305943A1 (en) * 2014-05-21 2017-10-26 Taxis Pharmaceuticals, Inc. Compounds for the treatment of bacterial infections
EP3419967A4 (en) 2016-02-25 2019-10-16 Taxis Pharmaceuticals, Inc. METHODS AND INTERMEDIARIES FOR SYNTHESIS
CA3058183A1 (en) * 2017-03-30 2018-10-04 Taxis Pharmaceuticals, Inc. Synthetic processes and synthetic intermediates
EP3752143A4 (en) * 2018-02-13 2021-08-11 Rutgers, The State University of New Jersey ANTIBACTERIAL AGENTS: O-ALKYL-DEUTERATED PYRONINS

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US190723A (en) * 1877-05-15 Improvement in washing-machines
US1375188A (en) * 1919-04-02 1921-04-19 Stern John Garter-support
DE3478573D1 (en) * 1983-09-01 1989-07-13 Duphar Int Res Benzoyl urea derivatives having anti-tumor activity
US4826990A (en) * 1987-09-30 1989-05-02 American Home Products Corporation 2-aryl substituted heterocyclic compounds as antiallergic and antiinflammatory agents
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
JPH11209350A (ja) * 1998-01-26 1999-08-03 Eisai Co Ltd 含窒素複素環誘導体およびその医薬
JP2002543130A (ja) * 1999-05-05 2002-12-17 メルク エンド カムパニー インコーポレーテッド 抗微生物剤としての新規なカテコール類
AU2002222552A1 (en) * 2000-11-29 2002-06-11 Kyorin Pharmaceutical Co. Ltd. Substituted carboxylic acid derivatives
US20050113450A1 (en) * 2002-08-23 2005-05-26 Atli Thorarensen Antibacterial agents
MX2008011857A (es) * 2006-03-23 2008-12-15 Prolysis Ltd Agentes antibacterianos.
GB0605881D0 (en) * 2006-03-23 2006-05-03 Prolysis Ltd Antibacterial Agents
WO2009081892A1 (ja) * 2007-12-25 2009-07-02 Kissei Pharmaceutical Co., Ltd. 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途
JP5883591B2 (ja) * 2010-08-06 2016-03-15 キッセイ薬品工業株式会社 新規なカテコール誘導体、それを含有する医薬組成物およびそれらの用途
JP2014523400A (ja) * 2011-04-20 2014-09-11 ビオタ サイエンティフィック マネジメント プティ リミテッド 芳香族アミド類およびそれらの使用
EP2828245A1 (en) * 2012-03-21 2015-01-28 Rutgers, The State University of New Jersey Antimicrobial agents
US9458150B2 (en) * 2013-11-08 2016-10-04 Rutgers, The State University Of New Jersey Antimicrobial agents

Also Published As

Publication number Publication date
ES2748665T3 (es) 2020-03-17
BR112015010570A2 (pt) 2017-07-11
EP2917212A1 (en) 2015-09-16
WO2014074932A1 (en) 2014-05-15
AU2013342095B2 (en) 2017-09-28
ZA201503372B (en) 2016-07-27
IL238677A0 (en) 2015-06-30
MX2015005753A (es) 2015-12-16
EP2917212B1 (en) 2019-06-12
CN104981469A (zh) 2015-10-14
DK2917212T3 (da) 2019-09-23
US20180179225A1 (en) 2018-06-28
JP6411355B2 (ja) 2018-10-24
JP2016501190A (ja) 2016-01-18
BR112015010570B1 (pt) 2020-03-17
KR20150096392A (ko) 2015-08-24
KR102163608B1 (ko) 2020-10-07
CA2891092A1 (en) 2014-05-15
PL2917212T3 (pl) 2020-03-31
CA2891092C (en) 2020-12-15
HK1215031A1 (zh) 2016-08-12
AU2013342095A1 (en) 2015-05-21
MX364443B (es) 2019-04-26
CN104981469B (zh) 2018-03-20
US20150307517A1 (en) 2015-10-29
IL238677B (en) 2019-05-30
SG11201503620RA (en) 2015-06-29

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B06T Formal requirements before examination [chapter 6.20 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B16C Correction of notification of the grant [chapter 16.3 patent gazette]

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