BR112015007659A8 - mecanismos químicos e métodos para o uso dos mesmos, especialmente na injeção de fluidos altamente viscosos - Google Patents

mecanismos químicos e métodos para o uso dos mesmos, especialmente na injeção de fluidos altamente viscosos Download PDF

Info

Publication number
BR112015007659A8
BR112015007659A8 BR112015007659A BR112015007659A BR112015007659A8 BR 112015007659 A8 BR112015007659 A8 BR 112015007659A8 BR 112015007659 A BR112015007659 A BR 112015007659A BR 112015007659 A BR112015007659 A BR 112015007659A BR 112015007659 A8 BR112015007659 A8 BR 112015007659A8
Authority
BR
Brazil
Prior art keywords
chemical mechanisms
injection
methods
highly viscous
viscous fluids
Prior art date
Application number
BR112015007659A
Other languages
English (en)
Other versions
BR112015007659A2 (pt
Inventor
M Heintz Amy
Kaseman Brian
H Muenzer Christopher
P Mckenzie Christopher
Bennison Corrie
L Ellis Jeffrey
M Madland Steven
M Blum Timothy
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR112015007659A2 publication Critical patent/BR112015007659A2/pt
Publication of BR112015007659A8 publication Critical patent/BR112015007659A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/19—Syringes having more than one chamber, e.g. including a manifold coupling two parallelly aligned syringes through separate channels to a common discharge assembly
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
    • C—CHEMISTRY; METALLURGY
    • C06—EXPLOSIVES; MATCHES
    • C06D—MEANS FOR GENERATING SMOKE OR MIST; GAS-ATTACK COMPOSITIONS; GENERATION OF GAS FOR BLASTING OR PROPULSION (CHEMICAL PART)
    • C06D5/00—Generation of pressure gas, e.g. for blasting cartridges, starting cartridges, rockets
    • C06D5/10—Generation of pressure gas, e.g. for blasting cartridges, starting cartridges, rockets by reaction of solids with liquids
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F01—MACHINES OR ENGINES IN GENERAL; ENGINE PLANTS IN GENERAL; STEAM ENGINES
    • F01B—MACHINES OR ENGINES, IN GENERAL OR OF POSITIVE-DISPLACEMENT TYPE, e.g. STEAM ENGINES
    • F01B1/00—Reciprocating-piston machines or engines characterised by number or relative disposition of cylinders or by being built-up from separate cylinder-crankcase elements
    • F01B1/01—Reciprocating-piston machines or engines characterised by number or relative disposition of cylinders or by being built-up from separate cylinder-crankcase elements with one single cylinder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/148—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags
    • A61M5/1483—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons flexible, e.g. independent bags using flexible bags externally pressurised by fluid pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
    • A61M5/281—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule
    • A61M5/282—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle using emptying means to expel or eject media, e.g. pistons, deformation of the ampoule, or telescoping of the ampoule by compression of deformable ampoule or carpule wall

Abstract

resumo patente de invenção: "mecanismos químicos e métodos para o uso dos mesmos, especialmente na injeção de fluidos altamente viscosos". a presente invenção refere-se a mecanismos químicos e processos para seu uso e construção. os mecanismos químicos podem fornecer dispositivos potentes e compactos, especificamente autoinjetores para a injeção potente e rápida de remédios viscosos. são descritas formulações e projetos inovadores de mecanismos químicos e tecnologias de entrega que empregam os mecanismos químicos.
BR112015007659A 2012-10-12 2013-10-15 mecanismos químicos e métodos para o uso dos mesmos, especialmente na injeção de fluidos altamente viscosos BR112015007659A8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261713250P 2012-10-12 2012-10-12
US201261713236P 2012-10-12 2012-10-12
US201361817312P 2013-04-29 2013-04-29
PCT/US2013/065136 WO2014059444A2 (en) 2012-10-12 2013-10-15 Chemical engines and methods for their use, especially in the injection of highly viscous fluids

Publications (2)

Publication Number Publication Date
BR112015007659A2 BR112015007659A2 (pt) 2017-07-04
BR112015007659A8 true BR112015007659A8 (pt) 2019-08-20

Family

ID=49725329

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015007659A BR112015007659A8 (pt) 2012-10-12 2013-10-15 mecanismos químicos e métodos para o uso dos mesmos, especialmente na injeção de fluidos altamente viscosos

Country Status (15)

Country Link
US (1) US9795740B2 (pt)
EP (2) EP2906273B1 (pt)
JP (3) JP6484175B2 (pt)
KR (2) KR101907809B1 (pt)
CN (2) CN104717994B (pt)
AU (2) AU2013328883B2 (pt)
BR (1) BR112015007659A8 (pt)
CA (2) CA2887296C (pt)
EA (2) EA201892121A1 (pt)
ES (1) ES2959157T3 (pt)
HK (1) HK1207595A1 (pt)
MX (1) MX2015004636A (pt)
UA (1) UA118179C2 (pt)
WO (1) WO2014059444A2 (pt)
ZA (1) ZA201501828B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2533878T3 (es) 2004-09-03 2015-04-15 L.O.M. Laboratories Inc. Jeringa retractable accionable por gas
JP6484175B2 (ja) 2012-10-12 2019-03-13 イーライ リリー アンド カンパニー 特に高度に粘性の流体の注射における、化学機関およびそれらの使用の方法
US9321581B2 (en) 2012-10-12 2016-04-26 Eli Lilly And Company Process and device for delivery of fluid by chemical reaction
CN107205938A (zh) * 2014-12-18 2017-09-26 温德加普医疗股份有限公司 用于溶解或增溶治疗剂的方法和组合物
KR102541205B1 (ko) 2015-02-20 2023-06-09 리제너론 파아마슈티컬스, 인크. 주사기 시스템, 피스톤 시일 시스템, 스토퍼 시스템 및 사용 방법 및 조립체
EP3380138A1 (en) * 2015-11-27 2018-10-03 Sanofi-Aventis Deutschland GmbH An injection device with an expandable cavity
CN105597188A (zh) * 2016-01-29 2016-05-25 江苏义倍医疗科技股份有限公司 医用输液装置
CA3014672C (en) * 2016-03-16 2020-07-21 Eli Lilly And Company Trigger assembly for automatic medication injection device
GB2556632A (en) * 2016-11-18 2018-06-06 Owen Mumford Ltd Medicament delivery device
WO2018129499A1 (en) 2017-01-09 2018-07-12 Verily Life Sciences Llc Systems and methods for wearable emergency drug injection devices
US11925790B2 (en) 2017-02-17 2024-03-12 Eli Lilly And Company Processes and devices for delivery of fluid by chemical reaction
US11577025B2 (en) 2017-06-29 2023-02-14 Regeneron Pharmaceuticals, Inc. Devices and methods for overfilling drug containers
EP3658208A1 (en) 2017-07-27 2020-06-03 Eli Lilly and Company Chemically driven auto-injector with retraction
CN111050826B (zh) * 2017-09-08 2022-05-31 伊莱利利公司 用于控制药物递送装置内的气体生成的系统
US10753780B2 (en) * 2018-03-12 2020-08-25 David Allan Brammer Liquid disperser
US11224537B2 (en) * 2018-10-19 2022-01-18 Alcon Inc. Intraocular gas injector
CA3123381A1 (en) 2018-12-19 2020-06-25 Eli Lilly And Company Devices for delivery of therapeutic fluids
CN113164681A (zh) * 2018-12-19 2021-07-23 伊莱利利公司 用于递送治疗性流体的装置和过程
US20220160954A1 (en) 2019-04-16 2022-05-26 Eli Lilly And Company Infusion head with controlled release of secondary drug
JP2020182722A (ja) * 2019-05-09 2020-11-12 株式会社三洋物産 遊技機
WO2021061802A2 (en) * 2019-09-23 2021-04-01 Battelle Memorial Institute Apparatus and methods of chemically-powered fluid flow systems
EP4076583A1 (en) * 2019-12-19 2022-10-26 Janssen Biotech, Inc. Liquid drug pumps with a flexible drug reservoir
US20240009403A1 (en) 2020-09-11 2024-01-11 Eli Lilly And Company Devices and processes for delivery of therapeutic fluids
EP4210788A1 (en) 2020-09-11 2023-07-19 Eli Lilly and Company Devices and processes for delivery of therapeutic fluids
WO2022055760A1 (en) 2020-09-11 2022-03-17 Eli Lilly And Company Devices and processes for delivery of therapeutic fluids
US11585042B2 (en) 2020-09-30 2023-02-21 Haier Us Appliance Solutions, Inc. Dryer appliance with additive dispenser
TWI806182B (zh) * 2020-11-18 2023-06-21 潔霺生醫科技股份有限公司 多段式氣體致動供藥裝置及方法
US11766520B2 (en) * 2021-03-22 2023-09-26 Nypro Inc. Reagent-catalyst driven single use hydraulic drive and single use large volume injector
WO2023006906A1 (en) 2021-07-28 2023-02-02 Shl Medical Ag Apparatus for large volume medication administration
CA3226493A1 (en) 2021-07-28 2023-02-02 Shl Medical Ag Apparatus for administration of medicine including monitoring and user feedback
CN116143743A (zh) * 2023-01-08 2023-05-23 太仓市茜泾化工有限公司 一种3-异丁基戊二酸酐的制备工艺及其制备装置

Family Cites Families (87)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2390246A (en) 1940-10-18 1945-12-04 Marvin L Folkman Syringe
US2446429A (en) * 1944-10-20 1948-08-03 Gen Electric Cellular phenolic resin
US2923243A (en) 1958-03-24 1960-02-02 Palmer Chemical & Equipment Co Projectile for liquid drug delivery to animals
US3380831A (en) * 1964-05-26 1968-04-30 Du Pont Photopolymerizable compositions and elements
US3467526A (en) 1965-02-19 1969-09-16 Gen Foods Corp Process for producing a supersaturated solution of carbon dioxide
JPS501700B1 (pt) * 1969-06-21 1975-01-21
US3773111A (en) * 1971-04-05 1973-11-20 B Dunn Fire extinguishing apparatus
US3802430A (en) * 1972-06-30 1974-04-09 L Arnold Disposable pyrotechnically powered injector
US3968796A (en) 1974-09-23 1976-07-13 Thomas G. Lutes Dental syringe
US3977402A (en) * 1975-03-25 1976-08-31 William Floyd Pike Injection apparatus and method with automatic aspiration feature
US4031889A (en) 1975-03-25 1977-06-28 William Floyd Pike Power operated aspirating hypodermic syringe
GB8416565D0 (en) * 1984-06-29 1984-08-01 Hoechst Uk Ltd Antibacterial derivatives
US4744786A (en) * 1986-06-17 1988-05-17 Cordis Corporation Infusion pump
US4785972A (en) 1987-07-14 1988-11-22 Adolph Coors Company Pressure generating system for a disposable container
DE3809482A1 (de) 1988-03-22 1989-10-19 Igor Groza Injektionsinstrument
US5062834A (en) * 1989-02-24 1991-11-05 Product Development (S.G.Z.) Ltd Device for dispensing a liquid particularly useful for delivering medicaments at a predetermined rate
US5034114A (en) * 1989-07-28 1991-07-23 Ira Kukin Acid neutralizing combustion additive with detergent builder
US5151093A (en) 1990-10-29 1992-09-29 Alza Corporation Osmotically driven syringe with programmable agent delivery
DE69226770T2 (de) 1991-04-24 1999-04-15 Orlitzky Anton Gasgenerator
US5167641A (en) 1991-05-29 1992-12-01 Arnis, Inc. Auto-retracting needle injector system
US5304128A (en) 1992-09-22 1994-04-19 Habley Medical Technology Corporation Gas powered self contained syringe
DK39293D0 (da) 1993-04-01 1993-04-01 Novo Nordisk As Dispenser sikret mod genbrug
WO1995001198A1 (en) 1993-07-02 1995-01-12 Ji Hoon Park Syringe
US5398850A (en) * 1993-08-06 1995-03-21 River Medical, Inc. Gas delivery apparatus for infusion
US5540665A (en) * 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
WO1996041159A1 (en) * 1995-06-07 1996-12-19 Ceramatec, Inc. Gas amplifier
US5700245A (en) * 1995-07-13 1997-12-23 Winfield Medical Apparatus for the generation of gas pressure for controlled fluid delivery
WO1997009078A1 (en) 1995-09-05 1997-03-13 Elan Medical Technologies Limited Chemically driven liquid delivery pumping device
US5645824A (en) 1995-10-02 1997-07-08 Lim; Min H. Color changing reagent composition for coating on needles used in medical applications
US5858001A (en) 1995-12-11 1999-01-12 Elan Medical Technologies Limited Cartridge-based drug delivery device
GB9602605D0 (en) 1996-02-09 1996-04-10 Weston Medical Ltd Injection aid
US5992700A (en) * 1997-05-28 1999-11-30 Apex Medical Technologies, Inc. Controlled gas generation for gas-driven infusion devices
US6500150B1 (en) 1997-06-16 2002-12-31 Elan Pharma International Limited Pre-filled drug-delivery device and method of manufacture and assembly of same
US5971722A (en) 1997-09-05 1999-10-26 Baxter International Inc Electrochemical syringe pump having a sealed storage reservoir for a charge transfer medium
US5941857A (en) 1997-09-12 1999-08-24 Becton Dickinson And Company Disposable pen needle
IE970782A1 (en) * 1997-10-22 1999-05-05 Elan Corp An improved automatic syringe
CA2334174A1 (en) 1998-06-04 1999-12-09 Izrail Tsals Gas driven drug delivery device
SE9803662D0 (sv) 1998-10-26 1998-10-26 Pharmacia & Upjohn Ab Autoinjector
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
US6086569A (en) 1999-05-04 2000-07-11 Schweizer; Kenneth M. Hypodermic syringe
US20010027293A1 (en) 1999-06-29 2001-10-04 Ashok V. Joshi Storage stable fluid injection device and associated process
US6601584B2 (en) 1999-09-17 2003-08-05 Pi Medical, Inc. Contracting snoring treatment implant
US6086568A (en) 1999-10-15 2000-07-11 Becton Dickinson And Company Syringe plunger rod for retracting needle syringe
FR2802103B1 (fr) 1999-12-08 2003-10-03 Poudres & Explosifs Ste Nale Seringue sans aiguille fonctionnant avec entrainement du principe actif par effet tube a choc
WO2002011791A1 (en) 2000-07-22 2002-02-14 Kim Yong Nyun Liquid supply apparatus
US6431468B1 (en) 2000-11-06 2002-08-13 Flexible Products Company Safety mechanism for dispensing apparatus
US6575961B2 (en) 2001-02-20 2003-06-10 Microlin, L.C. Fluid delivery device and associated method
WO2003039634A1 (en) 2001-11-09 2003-05-15 Alza Corporation Pneumatic powered autoinjector
KR100456273B1 (ko) 2001-11-16 2004-11-10 김용년 산과 반응하여 일정 속도로 이산화탄소를 발생시킬 수있는 고상 제제 및 그의 제조 방법
KR100507593B1 (ko) * 2002-02-08 2005-08-10 주식회사 이화양행 액체공급장치
KR101046903B1 (ko) * 2002-06-26 2011-07-06 인타르시아 세라퓨틱스 인코포레이티드 삼투성 약물 전달 시스템을 위한, 최소로 튀는 용적효율성 피스톤
CN100462111C (zh) * 2002-07-02 2009-02-18 松下电器产业株式会社 医用自动给药器
US8707959B2 (en) 2002-09-06 2014-04-29 Koninklijke Philips N.V. Implantable devices, systems, and methods for maintaining desired orientations in targeted tissue regions
US7618606B2 (en) * 2003-02-06 2009-11-17 The Ohio State University Separation of carbon dioxide (CO2) from gas mixtures
US20050027255A1 (en) * 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
AT413649B (de) 2003-08-04 2006-04-15 Pro Med Medizinische Produktio Vorrichtung zur dosierten abgabe einer flüssigkeit
US7632245B1 (en) 2003-08-18 2009-12-15 Medrad, Inc. Devices, systems and methods for delivery of a fluid into a patient during a magnetic resonance procedure
GB2410188B (en) 2004-01-23 2006-01-25 Medical House Plc Injection device
US7211065B2 (en) 2004-02-19 2007-05-01 Miller Stuart H Enveloping needle stick protection device
EP3263162B1 (en) 2004-08-13 2020-07-15 Becton, Dickinson and Company Retractable needle syringe assembly
JP4224442B2 (ja) * 2004-08-16 2009-02-12 大研医器株式会社 薬液注入装置
EP1877116A1 (en) 2005-04-13 2008-01-16 Novo Nordisk A/S Medical skin mountable device and system
US7337781B2 (en) 2005-04-15 2008-03-04 Restore Medical, Inc. Implant for tongue
BRPI0620062A2 (pt) 2005-12-20 2011-11-01 Novo Nordisk As Dispositivo de retenção da pele para uma unidade de injeção a jato médica
EP1993633B1 (en) 2006-02-09 2016-11-09 Deka Products Limited Partnership Pumping fluid delivery systems and methods using force application assembly
US8361019B2 (en) 2006-05-15 2013-01-29 Hillios Christopher H Injection aid and stability disk for syringe or insulin pen
US8827979B2 (en) 2007-03-19 2014-09-09 Insuline Medical Ltd. Drug delivery device
US8113390B2 (en) * 2007-04-18 2012-02-14 Microlin, Llc Gas generation dispenser apparatus and method for on-demand fluid delivery
US20090093787A1 (en) 2007-04-20 2009-04-09 Jennifer Barbour Ergonomic syringe
KR100819468B1 (ko) 2007-05-31 2008-04-08 (주)엠큐어 멀티 인젝션이 가능한 멀티홀 시술 장치
IL190335A0 (en) 2008-03-20 2009-09-22 Gaia Med Ltd Miniature disposable or partially reusable dosing pumps
US20090259176A1 (en) 2008-04-09 2009-10-15 Los Gatos Research, Inc. Transdermal patch system
JP4856733B2 (ja) 2008-04-28 2012-01-18 積水化学工業株式会社 マイクロポンプ装置
EP2303359B1 (en) 2008-05-29 2020-02-26 Roche Diabetes Care GmbH Modular medical infusion device with means for identification/authentication between its components
DE102008030270A1 (de) * 2008-06-19 2009-12-24 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Vorrichtung mit mindestens einer Kammer zur Aufnahme eines Medikaments oder eines Probenvolumens
GB0821492D0 (en) 2008-11-25 2008-12-31 Team Holdings Uk Ltd Integrated auto-injector cartridge system
US9375529B2 (en) 2009-09-02 2016-06-28 Becton, Dickinson And Company Extended use medical device
JP5677411B2 (ja) * 2009-04-29 2015-02-25 アッヴィ バイオテクノロジー リミテッド 自動注入機器
DE102009025375A1 (de) * 2009-06-18 2010-12-23 Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg Kolben für einen medizinischen Hohlkörper und medizinischer Hohlkörper
US8157769B2 (en) 2009-09-15 2012-04-17 Medimop Medical Projects Ltd. Cartridge insertion assembly for drug delivery system
WO2011092536A1 (en) * 2010-01-26 2011-08-04 Becton Dickinson France Drug cartrigde different inner surface conditions
US8475738B2 (en) 2010-05-04 2013-07-02 Electronics And Telecommunications Research Institute Photocatalytic apparatus and method for injecting microfluidic volumes
US8915879B2 (en) 2010-09-24 2014-12-23 Perqflo, Llc Infusion pumps
EP2489387A1 (en) 2011-02-18 2012-08-22 Sanofi-Aventis Deutschland GmbH Auto-injector
US9321581B2 (en) * 2012-10-12 2016-04-26 Eli Lilly And Company Process and device for delivery of fluid by chemical reaction
JP6484175B2 (ja) 2012-10-12 2019-03-13 イーライ リリー アンド カンパニー 特に高度に粘性の流体の注射における、化学機関およびそれらの使用の方法
CN105264705B (zh) * 2013-05-06 2019-07-19 斯蒂奇威特苏斯优良可持续水技术中心 用于从气体流产生能量的方法以及用于从烟道气产生能量的系统与设备

Also Published As

Publication number Publication date
HK1207595A1 (en) 2016-02-05
AU2013328883B2 (en) 2018-08-02
US20150314070A1 (en) 2015-11-05
EA201892121A1 (ru) 2019-02-28
BR112015007659A2 (pt) 2017-07-04
ES2959157T3 (es) 2024-02-21
EP2906273A2 (en) 2015-08-19
ZA201501828B (en) 2019-11-27
CN104717994B (zh) 2018-03-23
US9795740B2 (en) 2017-10-24
CA2887296C (en) 2018-12-04
WO2014059444A3 (en) 2014-08-21
CN104717994A (zh) 2015-06-17
JP2020203105A (ja) 2020-12-24
CA2887296A1 (en) 2014-04-17
EP4252801A3 (en) 2023-11-15
EA201590573A1 (ru) 2016-01-29
CA2991909A1 (en) 2014-04-17
EP4252801A2 (en) 2023-10-04
JP6484175B2 (ja) 2019-03-13
KR101723319B1 (ko) 2017-04-04
JP2015531311A (ja) 2015-11-02
JP7084454B2 (ja) 2022-06-14
CA2991909C (en) 2020-12-29
EA031645B1 (ru) 2019-02-28
CN108498904B (zh) 2021-02-12
AU2013328883A1 (en) 2015-03-26
KR20170038115A (ko) 2017-04-05
CN108498904A (zh) 2018-09-07
JP2019088893A (ja) 2019-06-13
EA201590573A8 (ru) 2018-09-28
UA118179C2 (uk) 2018-12-10
AU2018205095A1 (en) 2018-07-26
KR20150054932A (ko) 2015-05-20
WO2014059444A2 (en) 2014-04-17
MX2015004636A (es) 2015-10-22
AU2018205095B2 (en) 2019-04-18
KR101907809B1 (ko) 2018-10-12
EP2906273B1 (en) 2023-08-30

Similar Documents

Publication Publication Date Title
BR112015007659A8 (pt) mecanismos químicos e métodos para o uso dos mesmos, especialmente na injeção de fluidos altamente viscosos
BR112015011036A2 (pt) derivados de 2-amino-quinazolina substituídos heterocíclicos para o tratamento de infecções virais
CL2015001756A1 (es) Compuestos derivados de carbamoilpiridona policiclicos; composicion farmaceutica que los comprende; y su uso para el tratamiento de una infeccion de vih en un humano que tiene o se encuentra en riesgo de tener la infeccion.
BR112016013861A2 (pt) conjugados de droga e anticorpo, compostos, método de tratamento e composição farmacêutica
CL2016001447A1 (es) Uso de una solución acuosa de clorhexidina (<1%) para la preparación de un medicamento o dispositivos medicos de aplicación, para reducir la infección en un sujeto, en la sangre, tracto urogenital, tracto respiratorio, sitio intraperitoneal, colon, senos nasales, sitio intra-articular, en el mediastino o un sitio cerebroespinal.
CL2015000295A1 (es) Compuestos derivados de alquilpirimidina; composicion farmaceutica que los comprende; uso para el tratamiento de infecciones víricas y otras enfermedades.
CL2014002093A1 (es) Compuestos derivados piperidinopirimidinicos; composicion farmaceutica que los comprende; uso en el tratamiento de infecciones viricas.
CL2016000807A1 (es) Amino heteroarilo benzamidas como inhibidores de quinasa.
CL2015001314A1 (es) Anticuerpo de unión a tau; vector; célula hospedadora; hibridoma; péptido que comprende epítope de tau; composición farmacéutica que comprende al anticuerpo o al péptido de tau; dispositivo médico para administrarlos; y uso para tratar, prevenir o diagnosticar enfermedad de alzheimer o tautología relacionada (div. sol. n° 679-14).
BR112015020118A2 (pt) derivados de 2-aminopirimidina para o tratamento de infecções virais
BR112015014372A8 (pt) inibidores de autotaxina, seus usos, e composição e combinação farmacêuticas".
GT200900121A (es) Moleculas de enlace de lingo y uso farmaceutico
BR112015000150A2 (pt) composições farmacêuticas dissuasoras de abuso de liberação controlada
BR112015011171A2 (pt) compostos de pirrolopirimidina como inibidores da quinase
CL2015002733A1 (es) Composición farmacéutica de clorhidrato de s-cetamina.
AR092177A1 (es) Metodos para tratar o prevenir asma administrando un antagonista de il-4r
CL2014002237A1 (es) Anticuerpo anti-sez6; dicho anticuerpo conjugado con un fármaco; medicamento que los comprende; y uso para el tratamiento del cáncer.
BR112013028908A2 (pt) anticorpos c-kit e usos dos mesmos
BR112015024411A2 (pt) desaza-purinonas macrocíclicas para o tratamento de infeções virais
BRPI0809667A2 (pt) Composto, medicamento e composição farmacêutica que o contém e uso do composto
BR112015007366A2 (pt) derivados de acilaminopirimidina para o tratamento de infecções virais e outras doenças
BR112013017080A8 (pt) Anticorpo ou fragmento funcional do mesmo que se liga a forma ativa de calicreína do plasma humano, composiçao farmacêutica e método de detecçao de calicreína do plasma em um paciente
BR112015028244A2 (pt) Imunoconjugado que se liga ao folr1 e seu uso
GT201400059A (es) Derivados de estra-1,3,5(10),16-tetraen-3-carboxamida, proceidmientos para su preparación, preparados farmacéuticos que los contienen, así como su uso para la preparacion de medicamentos
BR112014022214A2 (pt) fenólicos antibacterianos

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements