BR112015006790B1 - Composição tópica e uso de cetoprofeno - Google Patents

Composição tópica e uso de cetoprofeno Download PDF

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Publication number
BR112015006790B1
BR112015006790B1 BR112015006790-5A BR112015006790A BR112015006790B1 BR 112015006790 B1 BR112015006790 B1 BR 112015006790B1 BR 112015006790 A BR112015006790 A BR 112015006790A BR 112015006790 B1 BR112015006790 B1 BR 112015006790B1
Authority
BR
Brazil
Prior art keywords
percent
ketoprofen
topical composition
composition
polyacrylic acid
Prior art date
Application number
BR112015006790-5A
Other languages
English (en)
Portuguese (pt)
Other versions
BR112015006790A2 (pt
Inventor
Servet Buyuktimkin
Nadir Buyuktimkin
James L. Yeager
Original Assignee
Achelios Therapeutics, Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Achelios Therapeutics, Inc filed Critical Achelios Therapeutics, Inc
Publication of BR112015006790A2 publication Critical patent/BR112015006790A2/pt
Publication of BR112015006790B1 publication Critical patent/BR112015006790B1/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
BR112015006790-5A 2012-09-27 2013-09-24 Composição tópica e uso de cetoprofeno BR112015006790B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261706163P 2012-09-27 2012-09-27
US61/706.163 2012-09-27
US13/826,706 US8822537B2 (en) 2012-09-27 2013-03-14 Topical ketoprofen composition
US13/826.706 2013-03-14
PCT/US2013/061403 WO2014052313A1 (en) 2012-09-27 2013-09-24 Topical ketoprofen composition

Publications (2)

Publication Number Publication Date
BR112015006790A2 BR112015006790A2 (pt) 2017-07-04
BR112015006790B1 true BR112015006790B1 (pt) 2022-05-31

Family

ID=50339476

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015006790-5A BR112015006790B1 (pt) 2012-09-27 2013-09-24 Composição tópica e uso de cetoprofeno

Country Status (13)

Country Link
US (1) US8822537B2 (https=)
EP (1) EP2900231B1 (https=)
JP (1) JP6238991B2 (https=)
KR (1) KR102184245B1 (https=)
AU (1) AU2013323766B2 (https=)
BR (1) BR112015006790B1 (https=)
CA (1) CA2885619C (https=)
ES (1) ES2902850T3 (https=)
IL (1) IL237810B (https=)
MX (1) MX373916B (https=)
NZ (1) NZ706108A (https=)
RU (1) RU2652345C2 (https=)
WO (1) WO2014052313A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6205133B2 (ja) 2009-07-10 2017-09-27 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
WO2016089893A1 (en) * 2014-12-01 2016-06-09 Achelios Therapeutics Inc. Methods and compositions for treating migraine and conditions associated with pain
KR20180069782A (ko) 2015-08-03 2018-06-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 하전 이온 채널 블록커 및 이용 방법
CA3045004A1 (en) * 2015-12-16 2017-06-22 Achelios Therapeutics, Inc. Methods and compositions for treating peripheral neuropathy
CA3019582A1 (en) * 2016-03-31 2017-10-05 Smartech Topical, Inc. Delivery system
AU2018376176A1 (en) * 2017-11-30 2020-07-02 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Stable liquid composition of ketoprofen, salts and enantiomers thereof
MX2021010869A (es) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueadores de canales iónicos sustituidos por éster y métodos para su uso.
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
AU2020235888A1 (en) 2019-03-11 2021-09-30 Nocion Therapeutics, Inc. Charged ION channel blockers and methods for use
US10934263B2 (en) 2019-03-11 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CA3139559A1 (en) 2019-05-09 2020-11-12 Apkarian Technologies Llc Methods and compositions for treating pain
JP7515582B2 (ja) * 2019-11-06 2024-07-12 スマーテック トピカル，インコーポレイテッド シクロオキシゲナーゼ阻害剤の局所配合剤およびその使用
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN114828845A (zh) 2019-11-06 2022-07-29 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN119118953A (zh) 2020-03-11 2024-12-13 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60155111A (ja) * 1983-10-20 1985-08-15 Hisamitsu Pharmaceut Co Inc 安定なケトプロフェン含有外用経皮製剤
US5863527A (en) * 1996-09-04 1999-01-26 The Proctor & Gamble Company Personal care compositions
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
FR2804024B1 (fr) 2000-01-21 2002-09-13 Menarini France Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation
CN1536983A (zh) * 2001-05-30 2004-10-13 宝洁公司 包括取代的化妆品键合剂的局部组合物
DE10141258B4 (de) * 2001-08-23 2004-09-23 Beiersdorf Ag Kosmetische und dermatologische Zubereitung und ihre Verwendung
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
ITFI20030070A1 (it) * 2003-03-18 2004-09-19 Berlin Chemie Ag Formulazioni topiche stabilizzate contenenti ketoprofene
EP1488787A1 (en) 2003-06-20 2004-12-22 Berlin-Chemie Ag Topical stabilized formulations containing ketoprofen
ATE534373T1 (de) * 2003-10-10 2011-12-15 Antares Pharma Ipl Ag Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut
US7928144B2 (en) * 2004-06-15 2011-04-19 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory and analgesic preparation for external use
EP1872796B1 (en) * 2005-02-25 2011-09-21 Hisamitsu Pharmaceutical Co., Inc. Transdermal preparation for external use containing nonsteroidal antiinflammatory/analgesic agent
AU2006290297A1 (en) * 2005-09-15 2007-03-22 Biomas Ltd. Use of tellurium compounds for protection from ultra-violet radiation
EP2010132A1 (en) * 2006-04-18 2009-01-07 DSMIP Assets B.V. Cosmetic compositions comprising salicylic acid and ascorbic acid
WO2009139817A2 (en) * 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8409600B2 (en) * 2009-01-23 2013-04-02 J&E Solutions, Llc Methods for prevention and/or treatment of capsular contracture
US20130109674A1 (en) * 2009-12-18 2013-05-02 Achelios Therapeutics Llc Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions

Also Published As

Publication number Publication date
MX2015004006A (es) 2015-10-29
KR102184245B1 (ko) 2020-11-30
JP2015531374A (ja) 2015-11-02
BR112015006790A2 (pt) 2017-07-04
US8822537B2 (en) 2014-09-02
CA2885619A1 (en) 2014-04-03
RU2652345C2 (ru) 2018-04-25
HK1212898A1 (en) 2016-06-24
JP6238991B2 (ja) 2017-11-29
KR20150074009A (ko) 2015-07-01
CA2885619C (en) 2020-09-08
US20140088195A1 (en) 2014-03-27
NZ706108A (en) 2018-03-23
EP2900231A1 (en) 2015-08-05
MX373916B (es) 2020-07-10
RU2015115723A (ru) 2016-11-20
IL237810B (en) 2018-06-28
EP2900231A4 (en) 2016-03-02
WO2014052313A1 (en) 2014-04-03
EP2900231B1 (en) 2021-11-03
ES2902850T3 (es) 2022-03-30
AU2013323766B2 (en) 2017-08-17
AU2013323766A1 (en) 2015-04-09

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/09/2013, OBSERVADAS AS CONDICOES LEGAIS

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A 12A ANUIDADE.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2846 DE 22-07-2025 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.