RU2652345C2 - Кетопрофеновая композиция для местного применения - Google Patents

Кетопрофеновая композиция для местного применения Download PDF

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Publication number
RU2652345C2
RU2652345C2 RU2015115723A RU2015115723A RU2652345C2 RU 2652345 C2 RU2652345 C2 RU 2652345C2 RU 2015115723 A RU2015115723 A RU 2015115723A RU 2015115723 A RU2015115723 A RU 2015115723A RU 2652345 C2 RU2652345 C2 RU 2652345C2
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RU
Russia
Prior art keywords
ketoprofen
composition
percent
carbopol
polyacrylic acid
Prior art date
Application number
RU2015115723A
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English (en)
Russian (ru)
Other versions
RU2015115723A (ru
Inventor
Сервет Буюктимкин
Надир Буюктимкин
Джеймс Л. Йиджер
Original Assignee
Ахелиос Терапьютикс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ахелиос Терапьютикс, Инк. filed Critical Ахелиос Терапьютикс, Инк.
Publication of RU2015115723A publication Critical patent/RU2015115723A/ru
Application granted granted Critical
Publication of RU2652345C2 publication Critical patent/RU2652345C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
RU2015115723A 2012-09-27 2013-09-24 Кетопрофеновая композиция для местного применения RU2652345C2 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261706163P 2012-09-27 2012-09-27
US61/706,163 2012-09-27
US13/826,706 2013-03-14
US13/826,706 US8822537B2 (en) 2012-09-27 2013-03-14 Topical ketoprofen composition
PCT/US2013/061403 WO2014052313A1 (en) 2012-09-27 2013-09-24 Topical ketoprofen composition

Publications (2)

Publication Number Publication Date
RU2015115723A RU2015115723A (ru) 2016-11-20
RU2652345C2 true RU2652345C2 (ru) 2018-04-25

Family

ID=50339476

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015115723A RU2652345C2 (ru) 2012-09-27 2013-09-24 Кетопрофеновая композиция для местного применения

Country Status (13)

Country Link
US (1) US8822537B2 (https=)
EP (1) EP2900231B1 (https=)
JP (1) JP6238991B2 (https=)
KR (1) KR102184245B1 (https=)
AU (1) AU2013323766B2 (https=)
BR (1) BR112015006790B1 (https=)
CA (1) CA2885619C (https=)
ES (1) ES2902850T3 (https=)
IL (1) IL237810B (https=)
MX (1) MX373916B (https=)
NZ (1) NZ706108A (https=)
RU (1) RU2652345C2 (https=)
WO (1) WO2014052313A1 (https=)

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JP6205133B2 (ja) 2009-07-10 2017-09-27 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
EP3226972A4 (en) * 2014-12-01 2018-08-08 Achelios Therapeutics, Inc. Methods and compositions for treating migraine and conditions associated with pain
AU2016301282B2 (en) 2015-08-03 2022-03-17 Children's Medical Center Corporation Charged ion channel blockers and methods for use
WO2017106714A1 (en) * 2015-12-16 2017-06-22 Achelios Therapeutics, Inc. Methods and compositions for treating peripheral neuropathy
KR20190003535A (ko) * 2016-03-31 2019-01-09 스마테크 토피칼, 인코포레이티드 전달 시스템
KR20200094161A (ko) * 2017-11-30 2020-08-06 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 케토프로펜, 이의 염 및 거울상 이성질체의 안정한 액체 조성물
BR112021017809A2 (pt) 2019-03-11 2021-11-23 Nocion Therapeutics Inc Bloqueadores de canais iônicos substituídos por éster e métodos para uso
AU2020234961C1 (en) 2019-03-11 2025-08-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10786485B1 (en) 2019-03-11 2020-09-29 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN113811305A (zh) 2019-03-11 2021-12-17 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
CA3139559A1 (en) 2019-05-09 2020-11-12 Apkarian Technologies Llc Methods and compositions for treating pain
WO2021091586A1 (en) 2019-11-06 2021-05-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US20220378729A1 (en) * 2019-11-06 2022-12-01 Smartech Topical, Inc. Topical formulations of cyclooxygenase inhibitors and their use
WO2021091585A1 (en) 2019-11-06 2021-05-14 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US11332446B2 (en) 2020-03-11 2022-05-17 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
WO2007118605A1 (en) * 2006-04-18 2007-10-25 Dsm Ip Assets B.V. Cosmetic compositions comprising salicylic acid and ascorbic acid
RU2340335C2 (ru) * 2003-03-18 2008-12-10 Менарини Ричерке С.П.А. Стабилизированные композиции для местного применения, содержащие кетопрофен
US20110028555A1 (en) * 2004-06-15 2011-02-03 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory and Analgesic Preparation for External Use

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Publication number Priority date Publication date Assignee Title
JPS60155111A (ja) * 1983-10-20 1985-08-15 Hisamitsu Pharmaceut Co Inc 安定なケトプロフェン含有外用経皮製剤
US5863527A (en) * 1996-09-04 1999-01-26 The Proctor & Gamble Company Personal care compositions
FR2804024B1 (fr) * 2000-01-21 2002-09-13 Menarini France Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation
CN1536983A (zh) * 2001-05-30 2004-10-13 宝洁公司 包括取代的化妆品键合剂的局部组合物
DE10141258B4 (de) * 2001-08-23 2004-09-23 Beiersdorf Ag Kosmetische und dermatologische Zubereitung und ihre Verwendung
EP1488787A1 (en) * 2003-06-20 2004-12-22 Berlin-Chemie Ag Topical stabilized formulations containing ketoprofen
DK1670433T3 (da) * 2003-10-10 2012-03-12 Ferring Bv Transdermal farmaceutisk formulering til mindskelse af hudrester
ES2370511T3 (es) * 2005-02-25 2011-12-19 Hisamitsu Pharmaceutical Co., Inc. Preparado transdérmico para uso externo que contiene un agente analgésico/antiinflamatorio no esteroideo.
CA2619073A1 (en) * 2005-09-15 2007-03-22 Biomas Ltd. Use of tellurium compounds for protection from ultra-violet radiation
US8080562B2 (en) * 2008-04-15 2011-12-20 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
US8409600B2 (en) * 2009-01-23 2013-04-02 J&E Solutions, Llc Methods for prevention and/or treatment of capsular contracture
WO2011075688A1 (en) * 2009-12-18 2011-06-23 Exodos Life Sciences Limited Partnership Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
RU2340335C2 (ru) * 2003-03-18 2008-12-10 Менарини Ричерке С.П.А. Стабилизированные композиции для местного применения, содержащие кетопрофен
US20110028555A1 (en) * 2004-06-15 2011-02-03 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory and Analgesic Preparation for External Use
WO2007118605A1 (en) * 2006-04-18 2007-10-25 Dsm Ip Assets B.V. Cosmetic compositions comprising salicylic acid and ascorbic acid

Also Published As

Publication number Publication date
EP2900231A1 (en) 2015-08-05
JP2015531374A (ja) 2015-11-02
IL237810B (en) 2018-06-28
BR112015006790A2 (pt) 2017-07-04
RU2015115723A (ru) 2016-11-20
JP6238991B2 (ja) 2017-11-29
KR102184245B1 (ko) 2020-11-30
WO2014052313A1 (en) 2014-04-03
ES2902850T3 (es) 2022-03-30
NZ706108A (en) 2018-03-23
HK1212898A1 (en) 2016-06-24
EP2900231B1 (en) 2021-11-03
KR20150074009A (ko) 2015-07-01
BR112015006790B1 (pt) 2022-05-31
EP2900231A4 (en) 2016-03-02
US8822537B2 (en) 2014-09-02
CA2885619A1 (en) 2014-04-03
MX373916B (es) 2020-07-10
US20140088195A1 (en) 2014-03-27
CA2885619C (en) 2020-09-08
MX2015004006A (es) 2015-10-29
AU2013323766A1 (en) 2015-04-09
AU2013323766B2 (en) 2017-08-17

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20200925

NF4A Reinstatement of patent

Effective date: 20211013