IL237810B - Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine - Google Patents

Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine

Info

Publication number
IL237810B
IL237810B IL237810A IL23781015A IL237810B IL 237810 B IL237810 B IL 237810B IL 237810 A IL237810 A IL 237810A IL 23781015 A IL23781015 A IL 23781015A IL 237810 B IL237810 B IL 237810B
Authority
IL
Israel
Prior art keywords
preparation
migraine
pain
treatment
effective amount
Prior art date
Application number
IL237810A
Other languages
English (en)
Hebrew (he)
Original Assignee
Achelios Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Achelios Therapeutics Inc filed Critical Achelios Therapeutics Inc
Publication of IL237810B publication Critical patent/IL237810B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
IL237810A 2012-09-27 2015-03-18 Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine IL237810B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261706163P 2012-09-27 2012-09-27
US13/826,706 US8822537B2 (en) 2012-09-27 2013-03-14 Topical ketoprofen composition
PCT/US2013/061403 WO2014052313A1 (en) 2012-09-27 2013-09-24 Topical ketoprofen composition

Publications (1)

Publication Number Publication Date
IL237810B true IL237810B (en) 2018-06-28

Family

ID=50339476

Family Applications (1)

Application Number Title Priority Date Filing Date
IL237810A IL237810B (en) 2012-09-27 2015-03-18 Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine

Country Status (13)

Country Link
US (1) US8822537B2 (https=)
EP (1) EP2900231B1 (https=)
JP (1) JP6238991B2 (https=)
KR (1) KR102184245B1 (https=)
AU (1) AU2013323766B2 (https=)
BR (1) BR112015006790B1 (https=)
CA (1) CA2885619C (https=)
ES (1) ES2902850T3 (https=)
IL (1) IL237810B (https=)
MX (1) MX373916B (https=)
NZ (1) NZ706108A (https=)
RU (1) RU2652345C2 (https=)
WO (1) WO2014052313A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6205133B2 (ja) 2009-07-10 2017-09-27 プレジデント アンド フェローズ オブ ハーバード カレッジ 抗炎症剤としての恒久的に荷電したナトリウムおよびカルシウムチャンネルブロッカー
WO2016089893A1 (en) * 2014-12-01 2016-06-09 Achelios Therapeutics Inc. Methods and compositions for treating migraine and conditions associated with pain
KR20180069782A (ko) 2015-08-03 2018-06-25 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 하전 이온 채널 블록커 및 이용 방법
CA3045004A1 (en) * 2015-12-16 2017-06-22 Achelios Therapeutics, Inc. Methods and compositions for treating peripheral neuropathy
CA3019582A1 (en) * 2016-03-31 2017-10-05 Smartech Topical, Inc. Delivery system
AU2018376176A1 (en) * 2017-11-30 2020-07-02 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Stable liquid composition of ketoprofen, salts and enantiomers thereof
MX2021010869A (es) 2019-03-11 2022-01-19 Nocion Therapeutics Inc Bloqueadores de canales iónicos sustituidos por éster y métodos para su uso.
US10780083B1 (en) 2019-03-11 2020-09-22 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
AU2020235888A1 (en) 2019-03-11 2021-09-30 Nocion Therapeutics, Inc. Charged ION channel blockers and methods for use
US10934263B2 (en) 2019-03-11 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
US10828287B2 (en) 2019-03-11 2020-11-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CA3139559A1 (en) 2019-05-09 2020-11-12 Apkarian Technologies Llc Methods and compositions for treating pain
JP7515582B2 (ja) * 2019-11-06 2024-07-12 スマーテック トピカル,インコーポレイテッド シクロオキシゲナーゼ阻害剤の局所配合剤およびその使用
US10933055B1 (en) 2019-11-06 2021-03-02 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN114828845A (zh) 2019-11-06 2022-07-29 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法
US12162851B2 (en) 2020-03-11 2024-12-10 Nocion Therapeutics, Inc. Charged ion channel blockers and methods for use
CN119118953A (zh) 2020-03-11 2024-12-13 诺西恩医疗公司 带电的离子通道阻滞剂及其使用方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60155111A (ja) * 1983-10-20 1985-08-15 Hisamitsu Pharmaceut Co Inc 安定なケトプロフェン含有外用経皮製剤
US5863527A (en) * 1996-09-04 1999-01-26 The Proctor & Gamble Company Personal care compositions
US6423697B1 (en) * 1999-01-14 2002-07-23 Mark Friedman Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache, facial pain, and cervical-muscle spasm
FR2804024B1 (fr) 2000-01-21 2002-09-13 Menarini France Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation
CN1536983A (zh) * 2001-05-30 2004-10-13 宝洁公司 包括取代的化妆品键合剂的局部组合物
DE10141258B4 (de) * 2001-08-23 2004-09-23 Beiersdorf Ag Kosmetische und dermatologische Zubereitung und ihre Verwendung
US7235230B2 (en) * 2001-10-24 2007-06-26 Clariant Finance (Bvi) Limited Leave-on compositions for personal care
ITFI20030070A1 (it) * 2003-03-18 2004-09-19 Berlin Chemie Ag Formulazioni topiche stabilizzate contenenti ketoprofene
EP1488787A1 (en) 2003-06-20 2004-12-22 Berlin-Chemie Ag Topical stabilized formulations containing ketoprofen
ATE534373T1 (de) * 2003-10-10 2011-12-15 Antares Pharma Ipl Ag Transdermale pharmazeutische formulierung zur minimierung von rückständen auf der haut
US7928144B2 (en) * 2004-06-15 2011-04-19 Hisamitsu Pharmaceutical Co., Inc. Antiinflammatory and analgesic preparation for external use
EP1872796B1 (en) * 2005-02-25 2011-09-21 Hisamitsu Pharmaceutical Co., Inc. Transdermal preparation for external use containing nonsteroidal antiinflammatory/analgesic agent
AU2006290297A1 (en) * 2005-09-15 2007-03-22 Biomas Ltd. Use of tellurium compounds for protection from ultra-violet radiation
EP2010132A1 (en) * 2006-04-18 2009-01-07 DSMIP Assets B.V. Cosmetic compositions comprising salicylic acid and ascorbic acid
WO2009139817A2 (en) * 2008-04-15 2009-11-19 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
US8409600B2 (en) * 2009-01-23 2013-04-02 J&E Solutions, Llc Methods for prevention and/or treatment of capsular contracture
US20130109674A1 (en) * 2009-12-18 2013-05-02 Achelios Therapeutics Llc Methods and compositions for treating and preventing trigeminal autonomic cephalgias, migraine, and vascular conditions

Also Published As

Publication number Publication date
BR112015006790B1 (pt) 2022-05-31
MX2015004006A (es) 2015-10-29
KR102184245B1 (ko) 2020-11-30
JP2015531374A (ja) 2015-11-02
BR112015006790A2 (pt) 2017-07-04
US8822537B2 (en) 2014-09-02
CA2885619A1 (en) 2014-04-03
RU2652345C2 (ru) 2018-04-25
HK1212898A1 (en) 2016-06-24
JP6238991B2 (ja) 2017-11-29
KR20150074009A (ko) 2015-07-01
CA2885619C (en) 2020-09-08
US20140088195A1 (en) 2014-03-27
NZ706108A (en) 2018-03-23
EP2900231A1 (en) 2015-08-05
MX373916B (es) 2020-07-10
RU2015115723A (ru) 2016-11-20
EP2900231A4 (en) 2016-03-02
WO2014052313A1 (en) 2014-04-03
EP2900231B1 (en) 2021-11-03
ES2902850T3 (es) 2022-03-30
AU2013323766B2 (en) 2017-08-17
AU2013323766A1 (en) 2015-04-09

Similar Documents

Publication Publication Date Title
IL237810B (en) Topical oil-in-water emulsion composition and use of a therapeutically effective amount of the composition for treating pain and migraine
IL285843A (en) Ibrutinib for use in the treatment of chronic graft versus host disease
IL283432A (en) Compositions, methods and systems for the treatment of cutaneous disorders
IL238432A0 (en) Methods and devices for the treatment of ocular diseases in human subjects
PT2919796T (pt) Utilização de akkermansia para o tratamento de distúrbios metabólicos
DK3043763T3 (da) Stimulerings- og behandlingsindretning
IL229474B (en) Cannabinoids for use in the treatment of neuropathic pain
IL244089A0 (en) Diagnostic methods and compositions for treatment of glioblastoma
BR112013018469A2 (pt) dispositivos e métodos para tratamento de tecidos
BR112014016240A2 (pt) dispositivo para tratamento de pele
DK2827813T3 (da) Kuldebehandlingsindretning
IL239478B (en) Prophylactic/therapeutic agent for dry eye
DK2522342T3 (da) Topisk formulering til behandling af hyperkeratonisk hud
EP3030084A4 (en) Organophosphates for the treatment of skin disorders
PT2900230T (pt) Compostos para o tratamento de obesidade e métodos de utilização dos mesmos
IL234606B (en) Novel methods and composition for treatment of disease
PT3071247T (pt) Dispositivo para a construção de pele
EP2983648A4 (en) COMBINATION THERAPEUTIC NANOPARTICLES
BR112015003162A2 (pt) dispositivo de modem e proessador de aplixcção
EP2609902A4 (en) PREPARATION OF A WATER IN OIL EMULSION COSMETICS
DK2986333T3 (da) Medicinsk hudapplikatorapparat
EP2839068A4 (en) Clothes treatment apparatus
HRP20181000T1 (hr) Postupci liječenja stanja povezanih s kosom
IL244881B (en) Hiv treatment formulation of atazanavir and cobicistat
BR112014029487A2 (pt) método para o tratamento cosmético

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed