BR112015004503A2 - liga de magnésio ultrapuro com taxa de degradação ajustável - Google Patents
liga de magnésio ultrapuro com taxa de degradação ajustávelInfo
- Publication number
- BR112015004503A2 BR112015004503A2 BR112015004503A BR112015004503A BR112015004503A2 BR 112015004503 A2 BR112015004503 A2 BR 112015004503A2 BR 112015004503 A BR112015004503 A BR 112015004503A BR 112015004503 A BR112015004503 A BR 112015004503A BR 112015004503 A2 BR112015004503 A2 BR 112015004503A2
- Authority
- BR
- Brazil
- Prior art keywords
- alloy
- less
- elements
- remainder
- matrix
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/02—Inorganic materials
- A61L27/04—Metals or alloys
- A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/84—Fasteners therefor or fasteners being internal fixation devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/58—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B21—MECHANICAL METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL; PUNCHING METAL
- B21C—MANUFACTURE OF METAL SHEETS, WIRE, RODS, TUBES OR PROFILES, OTHERWISE THAN BY ROLLING; AUXILIARY OPERATIONS USED IN CONNECTION WITH METAL-WORKING WITHOUT ESSENTIALLY REMOVING MATERIAL
- B21C23/00—Extruding metal; Impact extrusion
- B21C23/002—Extruding materials of special alloys so far as the composition of the alloy requires or permits special extruding methods of sequences
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C23/00—Alloys based on magnesium
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C23/00—Alloys based on magnesium
- C22C23/04—Alloys based on magnesium with zinc or cadmium as the next major constituent
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22F—CHANGING THE PHYSICAL STRUCTURE OF NON-FERROUS METALS AND NON-FERROUS ALLOYS
- C22F1/00—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working
- C22F1/06—Changing the physical structure of non-ferrous metals or alloys by heat treatment or by hot or cold working of magnesium or alloys based thereon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/12—Nanosized materials, e.g. nanofibres, nanoparticles, nanowires, nanotubes; Nanostructured surfaces
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Mechanical Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Materials Engineering (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Powder Metallurgy (AREA)
Abstract
abstract an alloy and an implant having a three-dimensional structure based on such alloy. the alloy comprises a monophasic mgzn alloy containing from 2.0 wt. % zn to 6 wt. % zn, having less than 0.001 wt. % of one or more other elements with the remainder being mg. in some embodiments, the alloy is substantially free of microgalvanic elements. in some embodiments, the alloy includes a mgznca alloy containing nanosized precipitates being less noble than the mg matrix alloy and having a zn content ranging from 3.0 wt. % zn to 6 wt. % zn and a calcium content ranging from 0.0005 wt. % to 1.0 wt. %, having less than 0.001 wt. % of one or more other elements with the remainder being mg. in other embodiments, the alloy includes a mgznca alloy containing nanosized precipitates being less noble than the mg matrix alloy, a plurality of nanosized precipitates being more noble than the mg matrix and having a zn content ranging from 3.0 wt. % zn to 6 wt. % zn, a calcium content ranging from 0.0005 wt. % to 1.0 wt. %, having less than 0.001 wt. % of one or more other elements with the remainder being mg. tradução do resumo resumo patente de invenção: "liga de magnésio ultrapuro com taxa de degradação ajustável". trata-se de uma liga e um implante que tem uma estrutura tridimensional com base em tal liga. a liga compreende uma liga de mgzn monofásica contendo de 2,0% em peso de zn a 6% em peso de zn, que tem menos que 0,001% em peso de um ou mais outros elementos em que o restante é mg. em algumas modalidades, a liga é substancialmente isenta de elementos microgalvânicos. em algumas modalidades, a liga inclui uma liga de mgznca contendo precipitados nanodimensionados que são menos nobres que a liga de matriz de mg e que têm um teor de zn na faixa de 3,0% em peso de zn a 6% em peso de zn e um teor de cálcio na faixa de 0,0005% em peso a 1,0% em peso, tendo menos que 0,001% em peso de um ou mais outros elementos, em que o restante é mg. em outras modalidades, a liga inclui uma liga de mgznca contendo precipitados nanodimensionados que são menos nobres que a liga de matriz de mg, em que uma pluralidade de precipitados nanodimensionados é mais nobre que a matriz de mg e tem um teor de zn na faixa de 3,0% em peso de zn a 6% em peso de zn, um teor de cálcio na faixa de 0,0005% em peso a 1,0% em peso, tendo menos que 0,001% em peso de um ou mais outros elementos, em que o restante é mg.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261695621P | 2012-08-31 | 2012-08-31 | |
US61/695,621 | 2012-08-31 | ||
US13/827,008 US9469889B2 (en) | 2012-08-31 | 2013-03-14 | Ultrapure magnesium alloy with adjustable degradation rate |
US13/827,008 | 2013-03-14 | ||
PCT/US2013/057294 WO2014036262A1 (en) | 2012-08-31 | 2013-08-29 | Ultrapure magnesium alloy with adjustable degradation rate |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112015004503A2 true BR112015004503A2 (pt) | 2017-07-04 |
BR112015004503B1 BR112015004503B1 (pt) | 2021-03-02 |
Family
ID=49162261
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015004503-0A BR112015004503B1 (pt) | 2012-08-31 | 2013-08-29 | composição de liga de mgznca, seu método de produção e implante |
Country Status (10)
Country | Link |
---|---|
US (2) | US9469889B2 (pt) |
EP (1) | EP2890824B1 (pt) |
JP (2) | JP6752575B2 (pt) |
KR (1) | KR102275471B1 (pt) |
CN (2) | CN104755644A (pt) |
BR (1) | BR112015004503B1 (pt) |
CA (1) | CA2883268C (pt) |
IN (1) | IN2015DN01751A (pt) |
TW (1) | TWI640638B (pt) |
WO (1) | WO2014036262A1 (pt) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
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US10895000B2 (en) | 2012-06-26 | 2021-01-19 | Biotronik Ag | Magnesium alloy, method for the production thereof and use thereof |
BR112014032649A2 (pt) | 2012-06-26 | 2017-06-27 | Biotronik Ag | liga de magnésio-zinco-cálcio, método de produção da mesma e seu uso |
US20150080998A1 (en) | 2012-06-26 | 2015-03-19 | Biotronik Ag | Magnesium-aluminum-zinc alloy, method for the production thereof and use thereof |
CN109022980A (zh) | 2012-06-26 | 2018-12-18 | 百多力股份公司 | 镁合金、其生产方法及其用途 |
US9469889B2 (en) | 2012-08-31 | 2016-10-18 | DePuy Synthes Products, Inc. | Ultrapure magnesium alloy with adjustable degradation rate |
EP2971206A1 (en) | 2013-03-14 | 2016-01-20 | DePuy Synthes Products, Inc. | Magnesium alloy with adjustable degradation rate |
US9593397B2 (en) | 2013-03-14 | 2017-03-14 | DePuy Synthes Products, Inc. | Magnesium alloy with adjustable degradation rate |
US20160206788A1 (en) * | 2013-06-12 | 2016-07-21 | The Regents Of The University Of California | Biomimetic interfaces for biodegradable metallic implants |
WO2016033312A1 (en) * | 2014-08-27 | 2016-03-03 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Magnesium enhanced/induced bone formation |
TWI610651B (zh) * | 2014-11-20 | 2018-01-11 | 財團法人金屬工業研究發展中心 | 鎂合金縫合釘 |
CN105568103A (zh) * | 2016-01-04 | 2016-05-11 | 青岛工学院 | 一种可降解生物医用镁合金 |
CN107227422A (zh) * | 2016-03-25 | 2017-10-03 | 武汉理工大学 | 一种高强度盐水可溶性镁合金材料及其制备方法 |
KR20170115429A (ko) | 2016-04-07 | 2017-10-17 | 랩앤피플주식회사 | 생체분해성 금속을 이용한 마이크로 니들 |
WO2017176077A1 (ko) * | 2016-04-07 | 2017-10-12 | 랩앤피플주식회사 | 생체분해성 금속을 이용한 마이크로 니들 |
KR101888091B1 (ko) * | 2016-10-31 | 2018-08-14 | 유앤아이 주식회사 | 생체분해 마그네슘 합금 및 그 제조방법 |
WO2018109947A1 (ja) * | 2016-12-16 | 2018-06-21 | 三協立山株式会社 | マグネシウム合金の製造方法およびマグネシウム合金 |
CN107236886B (zh) * | 2017-07-10 | 2018-09-07 | 太原理工大学 | 一种医用可降解高强韧耐蚀多元Mg-Zn-Y-Ca-Zr合金及其制备方法 |
CN107190192B (zh) * | 2017-07-10 | 2018-10-02 | 太原理工大学 | 一种可吸收生物医用高强韧耐蚀镁合金材料及其制备方法 |
CN107523732B (zh) * | 2017-08-15 | 2019-04-05 | 太原科技大学 | 一种含Na快速降解镁合金及其制备方法 |
CN108425051A (zh) * | 2018-03-29 | 2018-08-21 | 江苏理工学院 | 一种生物医用Mg-Sn-Zn-Ca镁合金及其制备方法 |
CN109112377B (zh) * | 2018-11-09 | 2020-06-02 | 吉林大学 | 一种耐蚀生物医用镁合金及其制备方法和应用 |
CN110438380B (zh) * | 2019-08-13 | 2021-02-26 | 中南大学 | 一种耐热阻燃镁合金及其形变热处理方法 |
EP4022104A4 (en) * | 2019-08-26 | 2023-09-27 | Ohio State Innovation Foundation | OBJECTS BASED ON MAGNESIUM ALLOY AND ASSOCIATED METHODS OF MANUFACTURING AND USE |
CN110604632A (zh) * | 2019-10-21 | 2019-12-24 | 中国人民解放军南部战区海军第一医院 | 生物可降解美容提拉线及其制备方法 |
JPWO2021215543A1 (pt) * | 2020-04-21 | 2021-10-28 | ||
JP2021079133A (ja) * | 2021-02-10 | 2021-05-27 | キュースリー メディカル デヴァイシズ リミテッドQ3 Medical Devices Limited | 生体分解性支持デバイス |
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CN101899600B (zh) | 2010-08-13 | 2012-04-25 | 上海交通大学 | 骨科用镁合金内植入材料及其制备方法 |
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WO2013107644A1 (de) | 2012-01-19 | 2013-07-25 | Eth Zurich | Verfahren und vorrichtung zur vakuumdestillation von hochreinem magnesium |
CN109022980A (zh) | 2012-06-26 | 2018-12-18 | 百多力股份公司 | 镁合金、其生产方法及其用途 |
BR112014032649A2 (pt) | 2012-06-26 | 2017-06-27 | Biotronik Ag | liga de magnésio-zinco-cálcio, método de produção da mesma e seu uso |
US9469889B2 (en) | 2012-08-31 | 2016-10-18 | DePuy Synthes Products, Inc. | Ultrapure magnesium alloy with adjustable degradation rate |
EP2971206A1 (en) | 2013-03-14 | 2016-01-20 | DePuy Synthes Products, Inc. | Magnesium alloy with adjustable degradation rate |
US9593397B2 (en) | 2013-03-14 | 2017-03-14 | DePuy Synthes Products, Inc. | Magnesium alloy with adjustable degradation rate |
-
2013
- 2013-03-14 US US13/827,008 patent/US9469889B2/en active Active
- 2013-08-29 WO PCT/US2013/057294 patent/WO2014036262A1/en unknown
- 2013-08-29 IN IN1751DEN2015 patent/IN2015DN01751A/en unknown
- 2013-08-29 EP EP13760203.3A patent/EP2890824B1/en active Active
- 2013-08-29 CN CN201380056515.7A patent/CN104755644A/zh active Pending
- 2013-08-29 CA CA2883268A patent/CA2883268C/en active Active
- 2013-08-29 JP JP2015530041A patent/JP6752575B2/ja active Active
- 2013-08-29 BR BR112015004503-0A patent/BR112015004503B1/pt active IP Right Grant
- 2013-08-29 KR KR1020157008005A patent/KR102275471B1/ko active IP Right Grant
- 2013-08-29 CN CN202010078762.9A patent/CN111304504A/zh active Pending
- 2013-08-30 TW TW102131181A patent/TWI640638B/zh active
-
2016
- 2016-09-07 US US15/258,387 patent/US10213522B2/en active Active
-
2018
- 2018-10-12 JP JP2018193365A patent/JP2019049056A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JP6752575B2 (ja) | 2020-09-09 |
US20140065009A1 (en) | 2014-03-06 |
TWI640638B (zh) | 2018-11-11 |
CN104755644A (zh) | 2015-07-01 |
US9469889B2 (en) | 2016-10-18 |
US20170000925A1 (en) | 2017-01-05 |
EP2890824B1 (en) | 2019-04-17 |
CN111304504A (zh) | 2020-06-19 |
EP2890824A1 (en) | 2015-07-08 |
BR112015004503B1 (pt) | 2021-03-02 |
TW201422822A (zh) | 2014-06-16 |
IN2015DN01751A (pt) | 2015-05-29 |
US10213522B2 (en) | 2019-02-26 |
CA2883268C (en) | 2021-01-05 |
KR102275471B1 (ko) | 2021-07-13 |
KR20150050586A (ko) | 2015-05-08 |
JP2019049056A (ja) | 2019-03-28 |
CA2883268A1 (en) | 2014-03-06 |
JP2015532685A (ja) | 2015-11-12 |
WO2014036262A1 (en) | 2014-03-06 |
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