BR112015002126A2 - método de alta eficiência para a purificação de partículas semelhante a vírus do papiloma vírus humano - Google Patents

método de alta eficiência para a purificação de partículas semelhante a vírus do papiloma vírus humano

Info

Publication number
BR112015002126A2
BR112015002126A2 BR112015002126A BR112015002126A BR112015002126A2 BR 112015002126 A2 BR112015002126 A2 BR 112015002126A2 BR 112015002126 A BR112015002126 A BR 112015002126A BR 112015002126 A BR112015002126 A BR 112015002126A BR 112015002126 A2 BR112015002126 A2 BR 112015002126A2
Authority
BR
Brazil
Prior art keywords
virus
purification
particles
high efficiency
human papilloma
Prior art date
Application number
BR112015002126A
Other languages
English (en)
Other versions
BR112015002126B1 (pt
Inventor
Kim Hong-Jin
Jin Kim Hyoung
Original Assignee
Hong Jin Kim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hong Jin Kim filed Critical Hong Jin Kim
Publication of BR112015002126A2 publication Critical patent/BR112015002126A2/pt
Publication of BR112015002126B1 publication Critical patent/BR112015002126B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01—DNA viruses
    • C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20051—Methods of production or purification of viral material

Abstract

ÿþr
BR112015002126-3A 2012-07-30 2013-07-30 Método de purificação das proteínas l1 do papiloma vírus humano BR112015002126B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR10-2012-0083472 2012-07-30
KR20120083472 2012-07-30
KR1020130085605A KR101559622B1 (ko) 2012-07-30 2013-07-19 인유두종바이러스 바이러스 유사입자의 고효율 정제방법
KR10-2013-0085605 2013-07-19
PCT/KR2013/006823 WO2014021604A1 (ko) 2012-07-30 2013-07-30 인유두종바이러스 바이러스 유사입자의 고효율 정제방법

Publications (2)

Publication Number Publication Date
BR112015002126A2 true BR112015002126A2 (pt) 2017-07-04
BR112015002126B1 BR112015002126B1 (pt) 2022-10-04

Family

ID=50266708

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015002126-3A BR112015002126B1 (pt) 2012-07-30 2013-07-30 Método de purificação das proteínas l1 do papiloma vírus humano

Country Status (11)

Country Link
US (1) US9994618B2 (pt)
EP (1) EP2881401B1 (pt)
JP (1) JP6014763B2 (pt)
KR (1) KR101559622B1 (pt)
CN (1) CN104507956B (pt)
AU (1) AU2013297306B2 (pt)
BR (1) BR112015002126B1 (pt)
CA (1) CA2880420C (pt)
CL (1) CL2015000037A1 (pt)
MX (1) MX361186B (pt)
WO (1) WO2014021604A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112017004181A2 (pt) * 2014-09-11 2017-12-05 Cadila Healthcare Ltd ?gene, vetor, célula hospedeira, partículas similares a vírus, vacina para vírus de papiloma humano, composição imunogênica, adjuvante, método para o preparo de uma vacina de papiloma humano, proteína de capsídeo principal e proteína hpv l1?
RU2677336C2 (ru) * 2014-12-26 2019-01-16 Айджин, Инк. Способ получения вирусоподобных частиц папилломавируса человека
CN105176934B (zh) * 2015-10-16 2018-09-18 西南大学柑桔研究所 柑桔黄化脉明病毒长期离体保存方法
CN109750050B (zh) * 2017-11-07 2023-08-18 上海泽润生物科技有限公司 重组人乳头瘤病毒45亚型蛋白表达

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122007000015I2 (de) 1997-09-05 2008-01-24 Medimmune Inc Methode zur in Vitro auseinander- und wiederzusammensetzung von Papillomavirus virusähnlichen Teilchen (vlps)
US7351533B2 (en) 1997-09-05 2008-04-01 Medimmune, Inc. In vitro method for disassmbly/reassembly of papillomavirus virus-like particles (VLPs). Homogeneous VLP and cavsomere compositions produced by said methods: use thereof as vehicle for improved purification, and delivery of active agents
BR9913026A (pt) 1998-08-14 2001-09-25 Merck & Co Inc Processo de purificação de partìculas semelhantes a vìrus (vlps) de papilomavìrus recombinante, e, processo de preparação de um produto de vlp de papilomavìrus humano purificado adequado para uso em uma vacina para humano
US6245568B1 (en) * 1999-03-26 2001-06-12 Merck & Co., Inc. Human papilloma virus vaccine with disassembled and reassembled virus-like particles
US6436402B1 (en) 1999-10-15 2002-08-20 Merck & Co., Inc. Process for making human papillomavirus virus-like particles with improved properties
DE60041889D1 (de) 1999-12-09 2009-05-07 Medimmune Inc In-vitro-methode zur zerlegung und zum wiederzusammenfügen von papillomavirusartigen partikeln
GB0206360D0 (en) 2002-03-18 2002-05-01 Glaxosmithkline Biolog Sa Viral antigens
CN101153280B (zh) 2006-09-29 2015-08-19 厦门大学 从原核生物中纯化人乳头瘤病毒晚期蛋白l1的方法
CN101139570A (zh) 2007-04-16 2008-03-12 马润林 一种hpv l1蛋白原核表达的高密度发酵方法
EP2907821B1 (en) 2007-05-29 2016-12-28 Xiamen University Method for producing a N-terminaly truncated L1 protein of human papillomavirus (HPV)
KR100959145B1 (ko) 2008-03-21 2010-05-25 중앙대학교 산학협력단 인유두종바이러스 바이러스 유사 입자의 생산 및 정제 방법
NZ590919A (en) 2008-07-31 2012-10-26 Glaxosmithkline Biolog Sa Vaccine against hpv
AU2009348078B2 (en) 2009-06-19 2013-03-14 Eyegene Inc. Vaccine for cervical cancer
KR101178056B1 (ko) 2011-12-19 2012-08-28 아이진 주식회사 자궁경부암 백신

Also Published As

Publication number Publication date
CA2880420C (en) 2018-02-27
JP6014763B2 (ja) 2016-10-25
EP2881401B1 (en) 2018-04-25
AU2013297306B2 (en) 2016-09-29
KR101559622B1 (ko) 2015-10-13
US9994618B2 (en) 2018-06-12
CA2880420A1 (en) 2014-02-06
MX2015001413A (es) 2015-11-18
JP2015524817A (ja) 2015-08-27
MX361186B (es) 2018-11-29
CN104507956A (zh) 2015-04-08
CN104507956B (zh) 2018-11-06
KR20140018794A (ko) 2014-02-13
EP2881401A4 (en) 2016-04-13
AU2013297306A1 (en) 2015-02-05
CL2015000037A1 (es) 2015-07-31
BR112015002126B1 (pt) 2022-10-04
US20150266927A1 (en) 2015-09-24
WO2014021604A1 (ko) 2014-02-06
EP2881401A1 (en) 2015-06-10

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11N Dismissal: publication cancelled [chapter 11.14 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: POSVAX CO., LTD (KR)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 30/07/2013, OBSERVADAS AS CONDICOES LEGAIS