CO6801768A2 - Procesos para la preparación de inhibidores del virus de la hepatitis - Google Patents
Procesos para la preparación de inhibidores del virus de la hepatitisInfo
- Publication number
- CO6801768A2 CO6801768A2 CO13259875A CO13259875A CO6801768A2 CO 6801768 A2 CO6801768 A2 CO 6801768A2 CO 13259875 A CO13259875 A CO 13259875A CO 13259875 A CO13259875 A CO 13259875A CO 6801768 A2 CO6801768 A2 CO 6801768A2
- Authority
- CO
- Colombia
- Prior art keywords
- processes
- preparation
- hepatitis virus
- virus inhibitors
- inhibitors
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Enzymes And Modification Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161482592P | 2011-05-04 | 2011-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO6801768A2 true CO6801768A2 (es) | 2013-11-29 |
Family
ID=47108028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO13259875A CO6801768A2 (es) | 2011-05-04 | 2013-11-01 | Procesos para la preparación de inhibidores del virus de la hepatitis |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20140044759A1 (es) |
| EP (2) | EP2704576A4 (es) |
| JP (2) | JP2014515764A (es) |
| KR (2) | KR20140030169A (es) |
| CN (2) | CN103476260A (es) |
| AR (1) | AR086259A1 (es) |
| AU (2) | AU2012250811A1 (es) |
| BR (2) | BR112013027652A2 (es) |
| CA (2) | CA2833887A1 (es) |
| CO (1) | CO6801768A2 (es) |
| IL (1) | IL228601A0 (es) |
| MX (2) | MX2013012771A (es) |
| RU (2) | RU2013153588A (es) |
| SG (1) | SG194711A1 (es) |
| TW (1) | TW201247668A (es) |
| WO (2) | WO2012151283A1 (es) |
| ZA (1) | ZA201308011B (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011014487A1 (en) | 2009-07-30 | 2011-02-03 | Merck Sharp & Dohme Corp. | Hepatitis c virus ns3 protease inhibitors |
| DK3010891T3 (da) * | 2013-06-19 | 2019-06-24 | Aicuris Anti Infective Cures Gmbh | Amorf letermovir og faste farmaceutiske formuleringer deraf til oral indgivelse |
| MX2019010452A (es) * | 2017-03-07 | 2019-10-15 | Orion Corp | Fabricacion de un producto farmaceutico cristalino. |
| US11351149B2 (en) | 2020-09-03 | 2022-06-07 | Pfizer Inc. | Nitrile-containing antiviral compounds |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR044694A1 (es) * | 2003-06-17 | 2005-09-21 | Schering Corp | Proceso y compuestos intermedios para la preparacion de (1r, 2s,5s) - 3 azabiciclo [3,1,0] hexano-2- carboxamida, n- [3- amino-1- (ciclobutilmetil) - 2, 3 - dioxopropil] -3- [ (2s) - 2 - [[ [ 1,1- dimetiletil] amino] carbonilamino] -3,3-dimetil -1- oxobutil]-6,6 dimetilo |
| AR056805A1 (es) * | 2005-11-14 | 2007-10-24 | Schering Corp | Un proceso para oxidacion para la preparcion de n- (3- amino-1- ( ciclobutilmetil) -2,3- dioxopropil ) -3-(n-(( ter-butilamino) carbonil )-3- metil- l- valil) -6,6- dimetil-3- azabiciclo (3.1.0) hexano -2- carboxamida y compuestos ralacionados |
| US8420122B2 (en) * | 2006-04-28 | 2013-04-16 | Merck Sharp & Dohme Corp. | Process for the precipitation and isolation of 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-amide compounds by controlled precipitation and pharmaceutical formulations containing same |
| CN101495095B (zh) * | 2006-04-28 | 2013-05-29 | 默沙东公司 | 通过受控的沉淀来沉淀和分离6,6-二甲基-3-氮杂-双环[3.1.0]己烷-酰胺化合物的方法和含有其的药学制剂 |
| JP4955779B2 (ja) * | 2006-12-20 | 2012-06-20 | シェーリング コーポレイション | （１ｒ，２ｓ，５ｓ）−ｎ−［（１ｓ）−３−アミノ−１−（シクロブチルメチル）−２，３−ジオキソプロピル］−３−［（２ｓ）−２−［［［（１，１−ジメチルエチル）アミノ］カルボニル］−アミノ］−３，３−ジメチル−１−オキソブチル］−６，６−ジメチル−３−アザビシクロ［３．１．０］ヘキサン−２−カルボキサミドを調製するための方法 |
| BRPI0806945A2 (pt) * | 2007-02-01 | 2014-05-06 | Tibotec Pharm Ltd | Formas polimórficas de um inibidor macrocíclico de hcv |
| JP4803074B2 (ja) * | 2007-03-06 | 2011-10-26 | 日産化学工業株式会社 | アルコール酸化触媒およびその合成方法 |
| CA2699280A1 (en) * | 2007-09-14 | 2009-03-26 | Schering Corporation | Method of treating hepatitis c patients |
| DE102009000662A1 (de) * | 2009-02-06 | 2010-08-12 | Evonik Degussa Gmbh | Verfahren zur Herstellung von Aldehyden und Ketonen aus primären und sekundären Alkoholen |
-
2012
- 2012-05-02 MX MX2013012771A patent/MX2013012771A/es unknown
- 2012-05-02 RU RU2013153588/15A patent/RU2013153588A/ru unknown
- 2012-05-02 RU RU2013153533/04A patent/RU2013153533A/ru not_active Application Discontinuation
- 2012-05-02 CA CA2833887A patent/CA2833887A1/en not_active Abandoned
- 2012-05-02 CN CN2012800200308A patent/CN103476260A/zh active Pending
- 2012-05-02 AU AU2012250811A patent/AU2012250811A1/en not_active Abandoned
- 2012-05-02 WO PCT/US2012/036131 patent/WO2012151283A1/en active Application Filing
- 2012-05-02 BR BR112013027652A patent/BR112013027652A2/pt not_active IP Right Cessation
- 2012-05-02 JP JP2014509384A patent/JP2014515764A/ja active Pending
- 2012-05-02 EP EP12779558.1A patent/EP2704576A4/en not_active Withdrawn
- 2012-05-02 WO PCT/US2012/036112 patent/WO2012151271A1/en active Application Filing
- 2012-05-02 JP JP2014509388A patent/JP2014513127A/ja active Pending
- 2012-05-02 CN CN201280020032.7A patent/CN103501608A/zh active Pending
- 2012-05-02 US US14/114,357 patent/US20140044759A1/en not_active Abandoned
- 2012-05-02 CA CA2832869A patent/CA2832869A1/en not_active Abandoned
- 2012-05-02 KR KR1020137028709A patent/KR20140030169A/ko not_active Application Discontinuation
- 2012-05-02 MX MX2013012773A patent/MX2013012773A/es unknown
- 2012-05-02 AU AU2012250799A patent/AU2012250799A1/en not_active Abandoned
- 2012-05-02 BR BR112013027642A patent/BR112013027642A2/pt not_active IP Right Cessation
- 2012-05-02 KR KR1020137028743A patent/KR20140022855A/ko not_active Application Discontinuation
- 2012-05-02 SG SG2013080643A patent/SG194711A1/en unknown
- 2012-05-02 EP EP12779536.7A patent/EP2704570A4/en not_active Withdrawn
- 2012-05-02 US US14/114,251 patent/US20140058116A1/en not_active Abandoned
- 2012-05-03 AR ARP120101561A patent/AR086259A1/es not_active Application Discontinuation
- 2012-05-04 TW TW101116053A patent/TW201247668A/zh unknown
-
2013
- 2013-09-29 IL IL228601A patent/IL228601A0/en unknown
- 2013-10-29 ZA ZA2013/08011A patent/ZA201308011B/en unknown
- 2013-11-01 CO CO13259875A patent/CO6801768A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP2704576A4 (en) | 2014-12-10 |
| NZ617300A (en) | 2015-06-26 |
| US20140044759A1 (en) | 2014-02-13 |
| AR086259A1 (es) | 2013-12-04 |
| CA2833887A1 (en) | 2012-11-08 |
| ZA201308011B (en) | 2015-05-27 |
| SG194711A1 (en) | 2013-12-30 |
| EP2704570A1 (en) | 2014-03-12 |
| JP2014513127A (ja) | 2014-05-29 |
| MX2013012771A (es) | 2013-11-21 |
| AU2012250811A1 (en) | 2013-12-19 |
| CN103476260A (zh) | 2013-12-25 |
| WO2012151283A1 (en) | 2012-11-08 |
| TW201247668A (en) | 2012-12-01 |
| BR112013027652A2 (pt) | 2016-07-26 |
| CN103501608A (zh) | 2014-01-08 |
| RU2013153533A (ru) | 2015-06-10 |
| EP2704570A4 (en) | 2015-02-18 |
| AU2012250799A1 (en) | 2013-10-10 |
| IL228601A0 (en) | 2013-12-31 |
| CA2832869A1 (en) | 2012-11-08 |
| KR20140022855A (ko) | 2014-02-25 |
| KR20140030169A (ko) | 2014-03-11 |
| EP2704576A1 (en) | 2014-03-12 |
| BR112013027642A2 (pt) | 2016-07-26 |
| JP2014515764A (ja) | 2014-07-03 |
| RU2013153588A (ru) | 2015-06-10 |
| MX2013012773A (es) | 2013-11-21 |
| US20140058116A1 (en) | 2014-02-27 |
| WO2012151271A1 (en) | 2012-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Application refused |