BR112014029280A2 - novos compostos - Google Patents
novos compostosInfo
- Publication number
- BR112014029280A2 BR112014029280A2 BR112014029280A BR112014029280A BR112014029280A2 BR 112014029280 A2 BR112014029280 A2 BR 112014029280A2 BR 112014029280 A BR112014029280 A BR 112014029280A BR 112014029280 A BR112014029280 A BR 112014029280A BR 112014029280 A2 BR112014029280 A2 BR 112014029280A2
- Authority
- BR
- Brazil
- Prior art keywords
- derivatives
- new compounds
- abstract
- diseases
- modulation
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 108010052164 Sodium Channels Proteins 0.000 abstract 1
- 102000018674 Sodium Channels Human genes 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003385 sodium Chemical class 0.000 abstract 1
- 125000003003 spiro group Chemical group 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261650325P | 2012-05-22 | 2012-05-22 | |
US61/650,325 | 2012-05-22 | ||
GB201209015A GB201209015D0 (en) | 2012-05-22 | 2012-05-22 | Novel compounds |
US201361773710P | 2013-03-06 | 2013-03-06 | |
US61/773,710 | 2013-03-06 | ||
GB1209015.5 | 2013-05-22 | ||
PCT/GB2013/051335 WO2013175205A1 (en) | 2012-05-22 | 2013-05-22 | Novel Compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014029280A2 true BR112014029280A2 (pt) | 2017-06-27 |
BR112014029280B1 BR112014029280B1 (pt) | 2022-10-04 |
Family
ID=46546493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014029280-9A BR112014029280B1 (pt) | 2012-05-22 | 2013-05-22 | Compostos derivados de espiro, composição farmacêutica compreendendo-os, processo para prepará-los e uso dos mesmos para tratar uma doença ou condição mediada por modulação de canais de sódio ativados por voltagem |
Country Status (28)
Country | Link |
---|---|
US (7) | US9309254B2 (pt) |
EP (3) | EP3106464B1 (pt) |
JP (3) | JP2015517562A (pt) |
KR (2) | KR20200113027A (pt) |
CN (2) | CN104640867B (pt) |
AU (3) | AU2013265001B2 (pt) |
BR (1) | BR112014029280B1 (pt) |
CA (1) | CA2873956C (pt) |
CY (2) | CY1118274T1 (pt) |
DK (2) | DK2861602T3 (pt) |
EA (1) | EA025579B1 (pt) |
ES (3) | ES2602308T3 (pt) |
GB (1) | GB201209015D0 (pt) |
HK (1) | HK1209423A1 (pt) |
HR (2) | HRP20161349T1 (pt) |
HU (2) | HUE049445T2 (pt) |
IL (4) | IL235805A (pt) |
IN (1) | IN2014MN02393A (pt) |
LT (2) | LT3106464T (pt) |
MX (1) | MX355303B (pt) |
PL (2) | PL3106464T3 (pt) |
PT (2) | PT3106464T (pt) |
RS (2) | RS60368B1 (pt) |
SG (2) | SG11201407755UA (pt) |
SI (2) | SI3106464T1 (pt) |
SM (1) | SMT201600421B (pt) |
WO (2) | WO2013175205A1 (pt) |
ZA (1) | ZA201408253B (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201122113D0 (en) | 2011-12-22 | 2012-02-01 | Convergence Pharmaceuticals | Novel compounds |
GB201209015D0 (en) | 2012-05-22 | 2012-07-04 | Convergence Pharmaceuticals | Novel compounds |
MA50669A (fr) * | 2017-09-28 | 2020-08-05 | Biogen Inc | Nouveaux sels |
CN111526874A (zh) * | 2017-10-10 | 2020-08-11 | 生物基因公司 | 用于制备螺环衍生物的方法 |
WO2022133097A1 (en) * | 2020-12-17 | 2022-06-23 | Biogen Ma Inc. | Synthesis of compounds that modulate use-dependent voltage-gated sodium channels |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA009789B1 (ru) * | 2002-07-05 | 2008-04-28 | Таргасепт, Инк. | N-арилдиазаспирациклические соединения и способы их получения и применения |
GB0520578D0 (en) * | 2005-10-10 | 2005-11-16 | Glaxo Group Ltd | Novel compounds |
TW200728258A (en) | 2005-10-10 | 2007-08-01 | Glaxo Group Ltd | Novel compounds |
WO2007042250A1 (en) | 2005-10-10 | 2007-04-19 | Glaxo Group Limited | Prolinamide derivatives as sodium channel modulators |
TW200730494A (en) | 2005-10-10 | 2007-08-16 | Glaxo Group Ltd | Novel compounds |
US8143306B2 (en) | 2005-10-10 | 2012-03-27 | Convergence Pharmaceuticals Limited | Methods of treating bipolar disorders |
CN101365690A (zh) * | 2005-10-12 | 2009-02-11 | 沃泰克斯药物股份有限公司 | 作为电压门控离子通道调控剂的联苯衍生物 |
WO2007084314A2 (en) * | 2006-01-12 | 2007-07-26 | Incyte Corporation | MODULATORS OF 11-ß HYDROXYL STEROID DEHYDROGENASE TYPE 1, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME |
MX2009003874A (es) | 2006-10-12 | 2009-04-22 | Xenon Pharmaceuticals Inc | Derivados de espiro-oxindol triciclicos y sus usos como agentes terapeuticos. |
TW200825091A (en) | 2006-10-12 | 2008-06-16 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds useful in treating sodium channel-mediated diseases or conditions |
GB0701365D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
GB0701366D0 (en) | 2007-01-24 | 2007-03-07 | Glaxo Group Ltd | Novel pharmaceutical compositions |
EA200970706A1 (ru) | 2007-01-24 | 2010-02-26 | Глэксо Груп Лимитед | Новые фармацевтические композиции |
GB0706630D0 (en) * | 2007-04-04 | 2007-05-16 | Glaxo Group Ltd | Novel compounds |
AR077252A1 (es) * | 2009-06-29 | 2011-08-10 | Xenon Pharmaceuticals Inc | Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos |
SI2477964T1 (sl) | 2009-09-14 | 2015-10-30 | Convergence Pharmaceuticals Limited | Postopek za pripravo derivatov alfa-karboksamida |
GB201122113D0 (en) | 2011-12-22 | 2012-02-01 | Convergence Pharmaceuticals | Novel compounds |
CN104205726B (zh) * | 2012-03-21 | 2018-02-13 | 交互数字专利控股公司 | 在无线网络中由另一移动基站赞助的移动基站会话 |
GB201209015D0 (en) | 2012-05-22 | 2012-07-04 | Convergence Pharmaceuticals | Novel compounds |
GB201209670D0 (en) | 2012-05-31 | 2012-07-18 | Convergence Pharmaceuticals | Novel compounds |
-
2012
- 2012-05-22 GB GB201209015A patent/GB201209015D0/en not_active Ceased
-
2013
- 2013-05-22 EA EA201492169A patent/EA025579B1/ru unknown
- 2013-05-22 JP JP2015513267A patent/JP2015517562A/ja not_active Withdrawn
- 2013-05-22 US US14/403,480 patent/US9309254B2/en not_active Expired - Fee Related
- 2013-05-22 EP EP16177700.8A patent/EP3106464B1/en active Active
- 2013-05-22 ES ES13725439.7T patent/ES2602308T3/es active Active
- 2013-05-22 CA CA2873956A patent/CA2873956C/en active Active
- 2013-05-22 CN CN201380038180.6A patent/CN104640867B/zh not_active Expired - Fee Related
- 2013-05-22 SG SG11201407755UA patent/SG11201407755UA/en unknown
- 2013-05-22 LT LTEP16177700.8T patent/LT3106464T/lt unknown
- 2013-05-22 PL PL16177700T patent/PL3106464T3/pl unknown
- 2013-05-22 HU HUE16177700A patent/HUE049445T2/hu unknown
- 2013-05-22 BR BR112014029280-9A patent/BR112014029280B1/pt not_active IP Right Cessation
- 2013-05-22 DK DK13725438.9T patent/DK2861602T3/en active
- 2013-05-22 ES ES16177700T patent/ES2782088T3/es active Active
- 2013-05-22 PL PL13725438T patent/PL2861602T3/pl unknown
- 2013-05-22 MX MX2014014274A patent/MX355303B/es active IP Right Grant
- 2013-05-22 SI SI201331705T patent/SI3106464T1/sl unknown
- 2013-05-22 PT PT161777008T patent/PT3106464T/pt unknown
- 2013-05-22 IN IN2393MUN2014 patent/IN2014MN02393A/en unknown
- 2013-05-22 WO PCT/GB2013/051335 patent/WO2013175205A1/en active Application Filing
- 2013-05-22 ES ES13725438.9T patent/ES2602193T3/es active Active
- 2013-05-22 PT PT137254389T patent/PT2861602T/pt unknown
- 2013-05-22 KR KR1020207027461A patent/KR20200113027A/ko not_active Application Discontinuation
- 2013-05-22 KR KR1020147035444A patent/KR102161101B1/ko active IP Right Grant
- 2013-05-22 SI SI201330339A patent/SI2861602T1/sl unknown
- 2013-05-22 EP EP13725439.7A patent/EP2861594B1/en active Active
- 2013-05-22 AU AU2013265001A patent/AU2013265001B2/en not_active Ceased
- 2013-05-22 JP JP2015513266A patent/JP6169687B2/ja not_active Expired - Fee Related
- 2013-05-22 SG SG10201703527WA patent/SG10201703527WA/en unknown
- 2013-05-22 CN CN201710522297.1A patent/CN107344942B/zh not_active Expired - Fee Related
- 2013-05-22 HU HUE13725438A patent/HUE031664T2/en unknown
- 2013-05-22 EP EP13725438.9A patent/EP2861602B1/en active Active
- 2013-05-22 DK DK16177700.8T patent/DK3106464T3/da active
- 2013-05-22 US US14/403,473 patent/US9376445B2/en active Active
- 2013-05-22 LT LTEP13725438.9T patent/LT2861602T/lt unknown
- 2013-05-22 RS RS20200393A patent/RS60368B1/sr unknown
- 2013-05-22 RS RS20160960A patent/RS55415B1/sr unknown
- 2013-05-22 WO PCT/GB2013/051336 patent/WO2013175206A1/en active Application Filing
-
2014
- 2014-11-11 ZA ZA2014/08253A patent/ZA201408253B/en unknown
- 2014-11-20 IL IL235805A patent/IL235805A/en active IP Right Grant
-
2015
- 2015-10-16 HK HK15110155.3A patent/HK1209423A1/xx not_active IP Right Cessation
-
2016
- 2016-02-15 US US15/043,920 patent/US20160184306A1/en not_active Abandoned
- 2016-05-25 US US15/163,845 patent/US9737536B2/en active Active
- 2016-10-17 HR HRP20161349TT patent/HRP20161349T1/hr unknown
- 2016-11-09 CY CY20161101143T patent/CY1118274T1/el unknown
- 2016-11-21 SM SM201600421T patent/SMT201600421B/it unknown
-
2017
- 2017-03-01 AU AU2017201421A patent/AU2017201421B2/en not_active Ceased
- 2017-04-30 IL IL252033A patent/IL252033B/en active IP Right Grant
- 2017-06-28 JP JP2017125716A patent/JP6378404B2/ja not_active Expired - Fee Related
- 2017-07-11 US US15/646,552 patent/US10010551B2/en active Active
-
2018
- 2018-03-07 AU AU2018201653A patent/AU2018201653B2/en not_active Ceased
- 2018-06-27 US US16/019,886 patent/US10485801B2/en not_active Expired - Fee Related
-
2019
- 2019-10-17 US US16/655,970 patent/US20200289508A1/en not_active Abandoned
- 2019-12-11 IL IL271330A patent/IL271330B/en active IP Right Grant
-
2020
- 2020-04-06 HR HRP20200580TT patent/HRP20200580T1/hr unknown
- 2020-04-07 CY CY20201100326T patent/CY1123044T1/el unknown
-
2021
- 2021-02-02 IL IL280595A patent/IL280595A/en unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112014010183B8 (pt) | Composto, composição farmacêutica, produto, e, uso de um composto | |
BR112018005497A2 (pt) | compostos heterocíclicos e usos dos mesmos | |
BR112017002053A2 (pt) | composto de acordo com a fórmula (i), composição farmacêutica, e usos de um composto | |
BR112017027414A2 (pt) | Derivados hidroxiéster, processo para prepará- los e composições farmacêuticas os contendo | |
BR112015008480A2 (pt) | compostos de benzeno substituído | |
TR201819138T4 (tr) | FGFR Kinaz Modülatörleri Olarak Faydalı Kinoksalin Türevleri | |
EA201391561A1 (ru) | Новые соединения-модуляторы gpr-119 | |
BR112014010206B8 (pt) | composto derivado de piridopirazina, composição farmacêutica, e, uso de um composto | |
BR112014016165A2 (pt) | compostos de benzaldeído substituído e métodos para seu uso no aumento da oxigenação do tecido | |
BR112014014452A2 (pt) | derivados de pirazolpiridina, processo de preparação dos mesmos e uso terapêutico dos mesmos | |
DOP2014000255A (es) | Uracilos sustituidos bicíclicamente y uso de los mismos | |
BR112014029706A8 (pt) | Composto, composição farmacêutica, e, uso de um composto | |
UY35210A (es) | Inhibidores de autotaxina | |
UY33735A (es) | Compuestos antivirales | |
CY1123456T1 (el) | Μεθοδος παρασκευης οπτικως καθαρων και προαιρετικως υποκατεστημενων παραγωγων 2-(1-υδροξυ-αλκυλ)-χρωμεν-4-ονης και χρηση αυτων στην παρασκευη φαρμακευτικων ουσιων | |
ECSP15000868A (es) | Derivados de estra1,3,5(10),16tetraeno 3sustituidos, métodos para su preparación, preparaciones farmacéuticas que los contienen, así como su uso para la preparación de medicamentos | |
SV2018005760A (es) | Derivados de aminotiazol utiles como agentes antiviricos | |
EA201591451A1 (ru) | Модуляторы flap | |
CL2018001210A1 (es) | Compuestos de criptoficina novedosos y productos conjugados, su preparación y su uso terapéutico. | |
UY35747A (es) | Derivados sustituidos de fenilalanina | |
BRPI0916622A2 (pt) | derivados de piperazina usados como moduladores de canal de cálcio cav2,2 | |
GT201400242A (es) | "nuevos compuestos de pirazol" | |
UY35746A (es) | Derivados de fenilalanina sustituidos | |
BR112014029280A2 (pt) | novos compostos | |
BR112015023878A2 (pt) | composto, composição farmacêutica, e, uso de um composto |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA. |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 22/05/2013, OBSERVADAS AS CONDICOES LEGAIS |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 11A ANUIDADE. |