BR112014025081A2 - Metabólito de colesterol, 5-colesten, 3beta- 25- diol, dissulfato (25hcds) para terapia de distúrbios metabólicos, hiperlipidemia, diabetes, doenças hepáticas gordurosas e aterosclerose - Google Patents
Metabólito de colesterol, 5-colesten, 3beta- 25- diol, dissulfato (25hcds) para terapia de distúrbios metabólicos, hiperlipidemia, diabetes, doenças hepáticas gordurosas e ateroscleroseInfo
- Publication number
- BR112014025081A2 BR112014025081A2 BR112014025081-2A BR112014025081A BR112014025081A2 BR 112014025081 A2 BR112014025081 A2 BR 112014025081A2 BR 112014025081 A BR112014025081 A BR 112014025081A BR 112014025081 A2 BR112014025081 A2 BR 112014025081A2
- Authority
- BR
- Brazil
- Prior art keywords
- 25hcds
- diol
- 3beta
- hyperlipidemia
- diabetes
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 208000031226 Hyperlipidaemia Diseases 0.000 title abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000030159 metabolic disease Diseases 0.000 title abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical class C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title 1
- 230000002440 hepatic effect Effects 0.000 title 1
- DTGDZMYNKLTSKC-HKQCOZBKSA-N cholest-5-ene Chemical compound C1C=C2CCCC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 DTGDZMYNKLTSKC-HKQCOZBKSA-N 0.000 abstract 2
- DTGDZMYNKLTSKC-UHFFFAOYSA-N cholest-5-ene Natural products C1C=C2CCCCC2(C)C2C1C1CCC(C(C)CCCC(C)C)C1(C)CC2 DTGDZMYNKLTSKC-UHFFFAOYSA-N 0.000 abstract 2
- VFNGKCDDZUSWLR-UHFFFAOYSA-L disulfate(2-) Chemical compound [O-]S(=O)(=O)OS([O-])(=O)=O VFNGKCDDZUSWLR-UHFFFAOYSA-L 0.000 abstract 2
- 208000010706 fatty liver disease Diseases 0.000 abstract 2
- 208000027866 inflammatory disease Diseases 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- -1 3beta-25-diol Chemical compound 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000004930 Fatty Liver Diseases 0.000 abstract 1
- 206010019708 Hepatic steatosis Diseases 0.000 abstract 1
- 101150014691 PPARA gene Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000003143 atherosclerotic effect Effects 0.000 abstract 1
- 150000001841 cholesterols Chemical class 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 231100000240 steatosis hepatitis Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261623203P | 2012-04-12 | 2012-04-12 | |
US201261623414P | 2012-04-12 | 2012-04-12 | |
US61/623,414 | 2012-04-12 | ||
US61/623,203 | 2012-04-12 | ||
PCT/US2013/031861 WO2013154752A1 (en) | 2012-04-12 | 2013-03-15 | A NOVEL CHOLESTEROL METABOLITE, 5-CHOLESTEN, 3β-25-DIOL, DISULFATE (25HCDS) FOR THERAPY OF METABOLIC DISORDERS, HYPERLIPIDEMIA, DIABETES, FATTY LIVER DISEASES AND ATHEROSCLEROSIS |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112014025081A2 true BR112014025081A2 (pt) | 2018-05-08 |
BR112014025081B1 BR112014025081B1 (pt) | 2020-12-08 |
Family
ID=49328028
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112014025081-2A BR112014025081B1 (pt) | 2012-04-12 | 2013-03-15 | metabólito de colesterol, 5-colesten-3,25-diol, dissulfato (25hcds), seu uso, composições compreendendo o mesmo, bem como processos de produção do referido composto e da referida composição |
Country Status (21)
Country | Link |
---|---|
US (6) | US20150072962A1 (pt) |
EP (2) | EP3239163A1 (pt) |
JP (4) | JP6125610B2 (pt) |
KR (1) | KR102180485B1 (pt) |
CN (2) | CN104220450B (pt) |
AU (2) | AU2013246435B2 (pt) |
BR (1) | BR112014025081B1 (pt) |
CA (1) | CA2867694C (pt) |
DK (1) | DK2836502T3 (pt) |
EA (1) | EA026683B1 (pt) |
ES (1) | ES2641841T3 (pt) |
HK (1) | HK1202294A1 (pt) |
HU (1) | HUE035073T2 (pt) |
IL (1) | IL234892B (pt) |
IN (1) | IN2014KN02366A (pt) |
MX (1) | MX357046B (pt) |
PL (1) | PL2836502T3 (pt) |
PT (1) | PT2836502T (pt) |
SI (1) | SI2836502T1 (pt) |
WO (1) | WO2013154752A1 (pt) |
ZA (1) | ZA201406981B (pt) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006047022A1 (en) | 2004-10-25 | 2006-05-04 | Virginia Commonwealth University | Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis |
US9034859B2 (en) | 2011-04-06 | 2015-05-19 | Virginia Commonwealth University | Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation |
EP3239163A1 (en) * | 2012-04-12 | 2017-11-01 | Virginia Commonwealth University | A novel cholesterol metabolite, 5-cholesten-3,25-diol, disulfate (25hcds) for therapy of metabolic disorders, hyperlipidemia, diabetes, fatty liver diseases and atherosclerosis |
US10272097B2 (en) * | 2013-12-24 | 2019-04-30 | Virginia Commonwealth University | Uses of oxygenated cholesterol sulfates (OCS) |
TWI547280B (zh) * | 2014-04-24 | 2016-09-01 | 長弘生物科技股份有限公司 | 穩定醫藥組合物 |
EP3166613A4 (en) | 2014-07-09 | 2018-02-21 | Duke University | Compositions and methods for the repair of myelin |
EA034524B1 (ru) * | 2014-10-10 | 2020-02-17 | Вирджиния Коммонвелт Юниверсити | Сульфаты окисленного холестерина для лечения пониженной лептиновой активности |
WO2016103722A1 (en) * | 2014-12-24 | 2016-06-30 | Kyoto University | Vitamin d3 derivatives and pharmaceutical use thereof |
AU2017306140A1 (en) * | 2016-08-02 | 2019-02-21 | Durect Corporation | Use of oxygenated cholesterol sulfates (OCS) to treat inflammatory skin disease and skin lesions |
WO2018026837A1 (en) * | 2016-08-02 | 2018-02-08 | Durect Corporation | Compositions comprising oxygenated cholesterol sulfate and at least one of polyalkylene glycol, carboxymethyl cellulose and polyoxylglyceride |
SI3494125T1 (sl) | 2016-08-02 | 2022-10-28 | Virginia Commonwealth University | Sestavki, ki vsebujejo 5-holesten-3, 25-diol, 3-sulfat(25HC3S) ali njegovo farmacevtsko sprejemljivo sol in vsaj en cikličen oligosaharid |
US11458146B2 (en) | 2017-01-13 | 2022-10-04 | Duke University | Compositions and methods for the treatment of myelin related and inflammation related diseases or disorders |
KR101892577B1 (ko) | 2017-04-21 | 2018-08-28 | 부산대학교 산학협력단 | 레블라스타틴 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 죽상동맥경화증 예방 또는 치료용 조성물 |
CN107286160A (zh) * | 2017-06-05 | 2017-10-24 | 毛佳婧 | 一种抗肝炎药物的哌啶并吡啶并吡唑‑锌配合物的制备方法 |
WO2019043700A1 (en) * | 2017-08-31 | 2019-03-07 | Ariel Scientific Innovations Ltd | S. SPINOSUM EXTRACT FOR THE TREATMENT OF HEPATIC STEATOSIS |
EP4037650A4 (en) * | 2019-09-30 | 2023-10-18 | Durect Corporation | TREATMENT OF ALCOHOLIC HEPATITIS |
CN112294827B (zh) * | 2020-11-12 | 2021-12-24 | 四川大学华西医院 | 5-胆甾烯 -3β-醇硫酸酯盐的用途 |
KR20230061860A (ko) | 2021-10-29 | 2023-05-09 | 부산대학교 산학협력단 | 크산틴 유도체를 유효성분으로 포함하는 죽상동맥경화증 예방 또는 치료용 약학적 조성물 |
WO2024008614A1 (en) * | 2022-07-08 | 2024-01-11 | Société des Produits Nestlé S.A. | Use of 25-hydroxycholesterol for diabetic treatment and/or prevention |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20020028876A (ko) * | 1999-04-30 | 2002-04-17 | 추후제출 | 스테로이드 유도체 |
WO2006047022A1 (en) * | 2004-10-25 | 2006-05-04 | Virginia Commonwealth University | Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis |
EP1983972A4 (en) | 2006-02-13 | 2012-01-25 | Wellstat Therapeutics Corp | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS |
US8003795B2 (en) | 2007-06-22 | 2011-08-23 | Cvi Pharmaceuticals Limited | Compounds and compositions for reducing lipid levels |
WO2011077245A2 (en) * | 2009-12-23 | 2011-06-30 | Fondazione Centro San Raffaele Del Monte Tabor | Compositions |
EP3239163A1 (en) * | 2012-04-12 | 2017-11-01 | Virginia Commonwealth University | A novel cholesterol metabolite, 5-cholesten-3,25-diol, disulfate (25hcds) for therapy of metabolic disorders, hyperlipidemia, diabetes, fatty liver diseases and atherosclerosis |
-
2013
- 2013-03-15 EP EP17167122.5A patent/EP3239163A1/en not_active Withdrawn
- 2013-03-15 SI SI201330794T patent/SI2836502T1/sl unknown
- 2013-03-15 WO PCT/US2013/031861 patent/WO2013154752A1/en active Application Filing
- 2013-03-15 MX MX2014012324A patent/MX357046B/es active IP Right Grant
- 2013-03-15 US US14/391,929 patent/US20150072962A1/en not_active Abandoned
- 2013-03-15 CN CN201380019476.3A patent/CN104220450B/zh active Active
- 2013-03-15 BR BR112014025081-2A patent/BR112014025081B1/pt not_active IP Right Cessation
- 2013-03-15 EA EA201491859A patent/EA026683B1/ru unknown
- 2013-03-15 PL PL13775974T patent/PL2836502T3/pl unknown
- 2013-03-15 DK DK13775974.2T patent/DK2836502T3/en active
- 2013-03-15 EP EP13775974.2A patent/EP2836502B1/en active Active
- 2013-03-15 JP JP2015505762A patent/JP6125610B2/ja not_active Expired - Fee Related
- 2013-03-15 HU HUE13775974A patent/HUE035073T2/en unknown
- 2013-03-15 AU AU2013246435A patent/AU2013246435B2/en not_active Ceased
- 2013-03-15 KR KR1020147031567A patent/KR102180485B1/ko active IP Right Grant
- 2013-03-15 PT PT137759742T patent/PT2836502T/pt unknown
- 2013-03-15 CA CA2867694A patent/CA2867694C/en active Active
- 2013-03-15 ES ES13775974.2T patent/ES2641841T3/es active Active
- 2013-03-15 CN CN201610412359.9A patent/CN106083976B/zh active Active
-
2014
- 2014-09-25 ZA ZA2014/06981A patent/ZA201406981B/en unknown
- 2014-09-28 IL IL234892A patent/IL234892B/en active IP Right Grant
- 2014-10-27 IN IN2366KON2014 patent/IN2014KN02366A/en unknown
-
2015
- 2015-03-17 HK HK15102737.7A patent/HK1202294A1/xx unknown
-
2016
- 2016-08-19 US US15/241,171 patent/US20160355544A1/en not_active Abandoned
-
2017
- 2017-04-05 JP JP2017074866A patent/JP2017160213A/ja active Pending
- 2017-10-10 US US15/728,827 patent/US20180127457A1/en not_active Abandoned
- 2017-11-30 AU AU2017268646A patent/AU2017268646B2/en not_active Ceased
-
2018
- 2018-09-25 US US16/140,964 patent/US20190135856A1/en not_active Abandoned
-
2019
- 2019-01-10 JP JP2019002297A patent/JP2019089777A/ja not_active Withdrawn
- 2019-10-10 US US16/599,044 patent/US20200157140A1/en not_active Abandoned
-
2020
- 2020-12-15 US US17/122,647 patent/US20210238219A1/en not_active Abandoned
-
2021
- 2021-05-14 JP JP2021082520A patent/JP2021138713A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR112014025081A2 (pt) | Metabólito de colesterol, 5-colesten, 3beta- 25- diol, dissulfato (25hcds) para terapia de distúrbios metabólicos, hiperlipidemia, diabetes, doenças hepáticas gordurosas e aterosclerose | |
FR23C1022I2 (fr) | Inhibiteurs du recyclage de l'acide biliaire pour traitement de maladies cholestatiques hepatiques pediatriques | |
BRPI0819690A2 (pt) | Método para tratar um paciente que sofre de doença do fígado gorduroso | |
BR112013030152A2 (pt) | método implantado por computador que habilita um formato de apresentação para um bloco de aplicativo | |
BR112013022712A2 (pt) | sistema e método de formar produto de confeitaria de múltiplas camadas | |
BR112013018877A2 (pt) | composições farmacêuticas que compreendem anticorpos humanos para pcsk9 | |
FR2980963B1 (fr) | Amelioration aux appareils refrigeres d'exposition de produits | |
DK2701695T3 (da) | Neurodegenerative lidelser og muskelsygdomme, der involverer polyumættede fedtsyrer | |
CL2014000995A1 (es) | Composicion de prodroga que comprende un conjugado de hidromorfona y un acido arilcarboxilico; un método para tratar un paciente que comprende la administracion de la composicion. | |
BR112015026513A2 (pt) | derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares | |
BR112018012590A2 (pt) | formas cristalinas polimórficas do ácido obeticólico | |
CR20140554A (es) | Compuestos de acido dimetil-benzoico | |
CL2013001604A1 (es) | Compuestos derivados de pirimidinona sustituida; composicion farmaceutica que los comprende; su uso para tratar la enfermedad de alzheimer y la aterosclerosis. | |
IL233639A0 (en) | Preparations and methods for the treatment of diseases and liver disorders | |
BR112015003561A2 (pt) | retinoides e sua utilização | |
BR112013031795A2 (pt) | método para tratar uma doença | |
BR112014005025A2 (pt) | composição farmacêutica para uso no tratamento de uma doença neurodegenerativa | |
BR112013021620A2 (pt) | métodos, aparelhos e sistemas para calcular uma quantia a ser cobrada em relação à execução de uma publicidade out-of-home durante um período de tempo | |
IL235000B (en) | Preparations for oral administration and their use for the treatment of motor disorders | |
BR112013030145A2 (pt) | processo para preparação de ácido metacrílico | |
FR2981572B1 (fr) | Compositions pharmaceutiques d'acide ursodesoxycholique | |
MX2015007082A (es) | Métodos de administración de composiciones que comprenden ácido docosapentanoico. | |
BR112013014307A2 (pt) | compostos que influenciam na captação e metabolismo de ácidos graxos e na produção de agentes inflamatórios e métodos de isolamento dos mesmos de produtos de cacau | |
CO6801771A2 (es) | Composición oral que comprende sodio divalproexy proceso para preparar la misma | |
FR2989272B1 (fr) | Composition procurant une sensation de refroidissement et utilisation d'un ester de sterol |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/03/2013, OBSERVADAS AS CONDICOES LEGAIS. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 11A ANUIDADE. |
|
B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2766 DE 09-01-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |