IN2014KN02366A - - Google Patents

Info

Publication number
IN2014KN02366A
IN2014KN02366A IN2366KON2014A IN2014KN02366A IN 2014KN02366 A IN2014KN02366 A IN 2014KN02366A IN 2366KON2014 A IN2366KON2014 A IN 2366KON2014A IN 2014KN02366 A IN2014KN02366 A IN 2014KN02366A
Authority
IN
India
Application number
Inventor
Shunlin Ren
Original Assignee
Virgina Commonwealth University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Virgina Commonwealth University filed Critical Virgina Commonwealth University
Publication of IN2014KN02366A publication Critical patent/IN2014KN02366A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IN2366KON2014 2012-04-12 2014-10-27 IN2014KN02366A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261623203P 2012-04-12 2012-04-12
US201261623414P 2012-04-12 2012-04-12
PCT/US2013/031861 WO2013154752A1 (en) 2012-04-12 2013-03-15 A NOVEL CHOLESTEROL METABOLITE, 5-CHOLESTEN, 3β-25-DIOL, DISULFATE (25HCDS) FOR THERAPY OF METABOLIC DISORDERS, HYPERLIPIDEMIA, DIABETES, FATTY LIVER DISEASES AND ATHEROSCLEROSIS

Publications (1)

Publication Number Publication Date
IN2014KN02366A true IN2014KN02366A (en) 2015-05-01

Family

ID=49328028

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2366KON2014 IN2014KN02366A (en) 2012-04-12 2014-10-27

Country Status (21)

Country Link
US (6) US20150072962A1 (en)
EP (2) EP2836502B1 (en)
JP (4) JP6125610B2 (en)
KR (1) KR102180485B1 (en)
CN (2) CN104220450B (en)
AU (2) AU2013246435B2 (en)
BR (1) BR112014025081B1 (en)
CA (1) CA2867694C (en)
DK (1) DK2836502T3 (en)
EA (1) EA026683B1 (en)
ES (1) ES2641841T3 (en)
HK (1) HK1202294A1 (en)
HU (1) HUE035073T2 (en)
IL (1) IL234892B (en)
IN (1) IN2014KN02366A (en)
MX (1) MX357046B (en)
PL (1) PL2836502T3 (en)
PT (1) PT2836502T (en)
SI (1) SI2836502T1 (en)
WO (1) WO2013154752A1 (en)
ZA (1) ZA201406981B (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006047022A1 (en) 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
US9034859B2 (en) 2011-04-06 2015-05-19 Virginia Commonwealth University Sulfated oxysterol and oxysterol sulfation by hydroxysterol sulfotransferase promote lipid homeostasis and liver proliferation
EA026683B1 (en) * 2012-04-12 2017-05-31 Вирджиния Коммонвелт Юниверсити CHOLESTEROL METABOLITE, 5-CHOLESTEN-3β-25-DIOL, DISULFATE (25HCDS) FOR THERAPY OF METABOLIC DISORDERS, HYPERLIPIDEMIA, DIABETES, FATTY LIVER DISEASES AND ATHEROSCLEROSIS
SI3086793T1 (en) 2013-12-24 2022-10-28 Virginia Commonwealth University Use of oxygenated cholesterol sulfates (ocs) for the treatment of kidney dysfunction
TWI547280B (en) * 2014-04-24 2016-09-01 長弘生物科技股份有限公司 Stable pharmaceutical composition
US10238664B2 (en) 2014-07-09 2019-03-26 Duke University Compositions and methods for the repair of myelin
JP2017530174A (en) * 2014-10-10 2017-10-12 ヴァージニア コモンウェルス ユニバーシティ Oxygenated cholesterol sulfate for treating disorders caused by at least one of impaired leptin activity and lipid accumulation disorders
EP3237377A4 (en) * 2014-12-24 2018-08-22 Kyoto University Vitamin d3 derivatives and pharmaceutical use thereof
AU2017306140A1 (en) 2016-08-02 2019-02-21 Durect Corporation Use of oxygenated cholesterol sulfates (OCS) to treat inflammatory skin disease and skin lesions
CA3031224A1 (en) 2016-08-02 2018-02-08 Shunlin Ren Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25hc3s) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide
TW201818946A (en) * 2016-08-02 2018-06-01 美商杜瑞克公司 Compositions comprising at least one oxygenated cholesterol sulfate and at least one of polyalkylene glycol, carboxymethyl cellulose and polyoxylglyceride, and methods for their use
CA3050001A1 (en) 2017-01-13 2018-07-19 Duke University Compositions and methods for the treatment of myelin related and inflammation related diseases or disorders
KR101892577B1 (en) 2017-04-21 2018-08-28 부산대학교 산학협력단 Composition for preventing or treating atherosclerosis comprising reblastatin derivation or pharmaceutical acceptable salts thereof
CN107286160A (en) * 2017-06-05 2017-10-24 毛佳婧 A kind of preparation method of the piperidines of Antihepatitis medicament and pyrido pyrazoles Zn complex
US20200197471A1 (en) * 2017-08-31 2020-06-25 Ariel Scientific Innovations Ltd S. spinosum extract for treating fatty liver disease
BR112022005039A2 (en) * 2019-09-30 2022-06-21 Durect Corp Treatment of alcoholic hepatitis
CN112294827B (en) * 2020-11-12 2021-12-24 四川大学华西医院 Application of 5-cholesten-3 beta-alcohol sulfate
KR20230061860A (en) 2021-10-29 2023-05-09 부산대학교 산학협력단 Pharmaceutical composition for preventing or treating atherosclerosis comprising a xanthine derivative as an active ingredient
WO2024008614A1 (en) * 2022-07-08 2024-01-11 Société des Produits Nestlé S.A. Use of 25-hydroxycholesterol for diabetic treatment and/or prevention

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1189922A4 (en) * 1999-04-30 2002-08-14 Arch Dev Corp Steroid derivatives
WO2006047022A1 (en) * 2004-10-25 2006-05-04 Virginia Commonwealth University Nuclear sulfated oxysterol, potent regulator of cholesterol homeostasis, for therapy of hypercholesterolemia, hyperlipidemia, and atherosclerosis
WO2007095462A2 (en) 2006-02-13 2007-08-23 Wellstat Therapeutics Corporation Compounds for the treatment of metabolic disorders
US8003795B2 (en) 2007-06-22 2011-08-23 Cvi Pharmaceuticals Limited Compounds and compositions for reducing lipid levels
WO2011077245A2 (en) * 2009-12-23 2011-06-30 Fondazione Centro San Raffaele Del Monte Tabor Compositions
EA026683B1 (en) * 2012-04-12 2017-05-31 Вирджиния Коммонвелт Юниверсити CHOLESTEROL METABOLITE, 5-CHOLESTEN-3β-25-DIOL, DISULFATE (25HCDS) FOR THERAPY OF METABOLIC DISORDERS, HYPERLIPIDEMIA, DIABETES, FATTY LIVER DISEASES AND ATHEROSCLEROSIS

Also Published As

Publication number Publication date
EP2836502A4 (en) 2015-08-19
PL2836502T3 (en) 2018-01-31
ES2641841T3 (en) 2017-11-14
MX2014012324A (en) 2015-05-11
CN106083976B (en) 2018-02-09
JP2015512937A (en) 2015-04-30
AU2017268646A1 (en) 2017-12-21
EA201491859A1 (en) 2015-02-27
KR102180485B1 (en) 2020-11-18
AU2017268646B2 (en) 2019-07-11
US20160355544A1 (en) 2016-12-08
CN104220450B (en) 2016-07-06
CA2867694A1 (en) 2013-10-17
EP3239163A1 (en) 2017-11-01
JP2019089777A (en) 2019-06-13
SI2836502T1 (en) 2017-11-30
CA2867694C (en) 2021-08-31
BR112014025081A2 (en) 2018-05-08
US20150072962A1 (en) 2015-03-12
KR20150013520A (en) 2015-02-05
EP2836502B1 (en) 2017-08-02
JP2017160213A (en) 2017-09-14
EA026683B1 (en) 2017-05-31
IL234892B (en) 2019-02-28
BR112014025081B1 (en) 2020-12-08
MX357046B (en) 2018-06-22
HK1202294A1 (en) 2015-09-25
ZA201406981B (en) 2016-05-25
DK2836502T3 (en) 2017-10-23
AU2013246435A1 (en) 2014-10-16
AU2013246435B2 (en) 2017-10-05
CN106083976A (en) 2016-11-09
US20210238219A1 (en) 2021-08-05
US20190135856A1 (en) 2019-05-09
HUE035073T2 (en) 2018-05-02
CN104220450A (en) 2014-12-17
US20180127457A1 (en) 2018-05-10
WO2013154752A1 (en) 2013-10-17
EP2836502A1 (en) 2015-02-18
US20200157140A1 (en) 2020-05-21
JP2021138713A (en) 2021-09-16
PT2836502T (en) 2017-10-27
JP6125610B2 (en) 2017-05-10

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