BR112013024467A2 - método e composições direcionadas para células adiposas em mamíferos - Google Patents
método e composições direcionadas para células adiposas em mamíferosInfo
- Publication number
- BR112013024467A2 BR112013024467A2 BR112013024467A BR112013024467A BR112013024467A2 BR 112013024467 A2 BR112013024467 A2 BR 112013024467A2 BR 112013024467 A BR112013024467 A BR 112013024467A BR 112013024467 A BR112013024467 A BR 112013024467A BR 112013024467 A2 BR112013024467 A2 BR 112013024467A2
- Authority
- BR
- Brazil
- Prior art keywords
- fat cells
- compositions directed
- mammalian fat
- mammalian
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Child & Adolescent Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161469345P | 2011-03-30 | 2011-03-30 | |
| PCT/US2012/031623 WO2012135729A2 (en) | 2011-03-30 | 2012-03-30 | Methods and compositions for targeting adipose cells in mammals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013024467A2 true BR112013024467A2 (pt) | 2019-09-24 |
Family
ID=46932409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013024467A BR112013024467A2 (pt) | 2011-03-30 | 2012-03-30 | método e composições direcionadas para células adiposas em mamíferos |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9029321B2 (pt) |
| EP (1) | EP2704736A4 (pt) |
| JP (1) | JP2014510758A (pt) |
| KR (1) | KR20140026408A (pt) |
| CN (1) | CN103703140B (pt) |
| AU (1) | AU2012236199A1 (pt) |
| BR (1) | BR112013024467A2 (pt) |
| CA (1) | CA2830375A1 (pt) |
| EA (1) | EA201391154A3 (pt) |
| IL (1) | IL228617A0 (pt) |
| MX (1) | MX2013011294A (pt) |
| SG (1) | SG193317A1 (pt) |
| WO (1) | WO2012135729A2 (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015123576A2 (en) * | 2014-02-17 | 2015-08-20 | The Brigham And Women's Hospital, Inc. | Targeted nanoparticle compositions and methods of their use to treat obesity |
| CN104774245A (zh) * | 2014-08-22 | 2015-07-15 | 天津药物研究院 | 一种脑靶向肽与抗肿瘤药偶联物的制备及应用 |
| AU2015342324B2 (en) * | 2014-11-03 | 2021-08-19 | Beijing Protgen Ltd. | Drug for inhibiting adipose cell differentiation and insulin resistance |
| CN104928320B (zh) * | 2015-07-03 | 2018-06-01 | 中国医学科学院医学生物学研究所 | 一种携带恒河猴抵抗素剪接体基因慢病毒载体的构建方法 |
| JP7445274B2 (ja) * | 2015-08-17 | 2024-03-07 | ザ ジョンズ ホプキンス ユニバーシティ | 組織修復のための間葉細胞結合複合材料 |
| CN106883299A (zh) * | 2015-12-16 | 2017-06-23 | 杭州阿德莱诺泰制药技术有限公司 | 脂肪组织靶向多肽及其制备方法和应用 |
| CN106749524B (zh) * | 2016-12-05 | 2020-08-18 | 华南理工大学 | 一种抗肥胖七肽npvwkrk |
| TW201822809A (zh) | 2016-12-15 | 2018-07-01 | 深圳瑞健生命科學硏究院有限公司 | 一種預防和治療高脂血症的方法 |
| WO2018108161A1 (zh) | 2016-12-15 | 2018-06-21 | 深圳瑞健生命科学研究院有限公司 | 一种预防和治疗肥胖症的方法和药物 |
| CN107496900B (zh) * | 2017-09-06 | 2020-10-16 | 首都医科大学附属北京同仁医院 | 一种调控棕色脂肪组织活性的方法 |
| CN107569679B (zh) * | 2017-09-06 | 2020-10-16 | 首都医科大学附属北京同仁医院 | Ace2在调控棕色脂肪组织活性中的应用 |
| CN107996826A (zh) * | 2017-10-27 | 2018-05-08 | 威海同丰海洋生物科技有限公司 | 一种含有防御素的饲料添加剂及其制备方法 |
| CN109276704A (zh) * | 2017-11-07 | 2019-01-29 | 江苏省中医药研究院 | 蜂毒肽在制备治疗和/或预防糖尿病的药物或保健品中的用途 |
| WO2019165134A1 (en) * | 2018-02-21 | 2019-08-29 | Texas Tech University System | Particles for targeted delivery of active agents into adipose stromal cells |
| CN109402102B (zh) * | 2018-11-09 | 2021-12-03 | 临沂大学 | 一种表面附有半透保护膜的酶-磷脂微囊的制备方法 |
| KR102143531B1 (ko) * | 2018-12-20 | 2020-08-12 | 영남대학교 산학협력단 | 탈리도마이드를 유효성분으로 함유하는 가축 육질 개선용 조성물 |
| KR102112702B1 (ko) * | 2019-12-19 | 2020-05-19 | (주)슈퍼노바 바이오 | 표면 개질된 가스-생성 나노입자를 이용한 지방 분해용 조성물 |
| MX2022008595A (es) * | 2020-01-15 | 2022-08-10 | Supernova Bio Co Ltd | Micela generadora de gas para reducir grasa localizada. |
| EP4132554A4 (en) * | 2020-04-07 | 2024-06-05 | Univ Arizona | PEPTIDES AGAINST OBESITY AND THEIR USES |
| WO2023014375A1 (en) * | 2021-08-06 | 2023-02-09 | Lean Life Sciences, Inc | Cosmetic peptides for improving skin rejuvenation |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040170955A1 (en) | 2000-09-08 | 2004-09-02 | Wadih Arap | Human and mouse targeting peptides identified by phage display |
| US20050074747A1 (en) | 2000-09-08 | 2005-04-07 | Wadih Arap | Biopanning and rapid analysis of selective interactive ligands (brasil) |
| US7452964B2 (en) * | 2001-09-07 | 2008-11-18 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides against placenta and adipose tissues |
| US7214786B2 (en) | 2000-12-14 | 2007-05-08 | Kovalic David K | Nucleic acid molecules and other molecules associated with plants and uses thereof for plant improvement |
| JP2004529621A (ja) * | 2001-02-14 | 2004-09-30 | ティー ファークト，レオ | 多能性成体幹細胞、その起源、それを得る方法および維持する方法、それを分化させる方法、その使用法、ならびにそれ由来の細胞 |
| US7671010B2 (en) | 2002-08-30 | 2010-03-02 | The Board Of Regents Of The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
| US8507445B2 (en) | 2001-09-07 | 2013-08-13 | Board Of Regents, The University Of Texas System | Compositions and methods of use of targeting peptides for diagnosis and therapy of human cancer |
| US7314974B2 (en) | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
| WO2007046818A2 (en) | 2004-11-16 | 2007-04-26 | Board Of Regents, The University Of Texas System | Compositions and methods related to synchronous selection of homing peptides for multiple tissues by in vivo phage display |
| WO2008143679A2 (en) | 2006-06-01 | 2008-11-27 | Verenium Corporation | Nucleic acids and proteins and methods for making and using them |
| CN101970679B (zh) | 2008-01-03 | 2015-04-22 | 嘉吉公司 | 氨基转移酶和氧化还原酶核酸和多肽和使用方法 |
| ES2531290T3 (es) | 2008-01-03 | 2015-03-12 | Basf Enzymes Llc | Transferasas y oxidorreductasas, ácidos nucleicos que las codifican y métodos para prepararlas y usarlas |
| DE112009002577T5 (de) | 2008-10-23 | 2012-06-21 | Basf Plant Science Gmbh | Pflanzen mit erhöhtem Ertrag (NUE) |
| CN102120755B (zh) * | 2010-04-23 | 2013-04-03 | 江苏省人民医院 | 一种棕色脂肪组织靶向性多肽及其应用 |
| CN102120034B (zh) * | 2010-04-23 | 2015-02-11 | 江苏省人民医院 | 一种靶向至棕色脂肪组织治疗肥胖的新型靶向药物 |
| WO2012169911A1 (en) * | 2011-06-10 | 2012-12-13 | Auckland Uniservices Limited | Peptides, constructs and uses therefor |
-
2012
- 2012-03-30 KR KR1020137027109A patent/KR20140026408A/ko not_active Application Discontinuation
- 2012-03-30 BR BR112013024467A patent/BR112013024467A2/pt not_active IP Right Cessation
- 2012-03-30 EP EP12764703.0A patent/EP2704736A4/en not_active Withdrawn
- 2012-03-30 MX MX2013011294A patent/MX2013011294A/es unknown
- 2012-03-30 EA EA201391154A patent/EA201391154A3/ru unknown
- 2012-03-30 AU AU2012236199A patent/AU2012236199A1/en not_active Abandoned
- 2012-03-30 JP JP2014502865A patent/JP2014510758A/ja active Pending
- 2012-03-30 CA CA2830375A patent/CA2830375A1/en not_active Abandoned
- 2012-03-30 SG SG2013066782A patent/SG193317A1/en unknown
- 2012-03-30 WO PCT/US2012/031623 patent/WO2012135729A2/en active Application Filing
- 2012-03-30 US US14/007,836 patent/US9029321B2/en active Active
- 2012-03-30 CN CN201280023148.6A patent/CN103703140B/zh not_active Expired - Fee Related
-
2013
- 2013-09-29 IL IL228617A patent/IL228617A0/en unknown
-
2015
- 2015-04-09 US US14/682,335 patent/US9539341B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN103703140A (zh) | 2014-04-02 |
| WO2012135729A9 (en) | 2014-01-30 |
| AU2012236199A1 (en) | 2013-09-26 |
| US9029321B2 (en) | 2015-05-12 |
| EP2704736A2 (en) | 2014-03-12 |
| US20140243258A1 (en) | 2014-08-28 |
| SG193317A1 (en) | 2013-10-30 |
| US9539341B2 (en) | 2017-01-10 |
| EP2704736A4 (en) | 2016-07-20 |
| EA201391154A2 (ru) | 2014-06-30 |
| MX2013011294A (es) | 2014-10-06 |
| JP2014510758A (ja) | 2014-05-01 |
| KR20140026408A (ko) | 2014-03-05 |
| EA201391154A3 (ru) | 2016-01-29 |
| US20160000930A1 (en) | 2016-01-07 |
| CN103703140B (zh) | 2017-02-22 |
| WO2012135729A2 (en) | 2012-10-04 |
| IL228617A0 (en) | 2013-12-31 |
| CA2830375A1 (en) | 2012-10-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |