BR112013024401A2 - métodos e composições para o tratamento do transtorno do déficit de atenção - Google Patents

métodos e composições para o tratamento do transtorno do déficit de atenção

Info

Publication number
BR112013024401A2
BR112013024401A2 BR112013024401A BR112013024401A BR112013024401A2 BR 112013024401 A2 BR112013024401 A2 BR 112013024401A2 BR 112013024401 A BR112013024401 A BR 112013024401A BR 112013024401 A BR112013024401 A BR 112013024401A BR 112013024401 A2 BR112013024401 A2 BR 112013024401A2
Authority
BR
Brazil
Prior art keywords
compositions
treatment
methods
attention deficit
deficit disorder
Prior art date
Application number
BR112013024401A
Other languages
English (en)
Other versions
BR112013024401B1 (pt
Inventor
Lickrish David
Zhang Feng
Original Assignee
Ironshore Pharmaceuticals & Dev Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ironshore Pharmaceuticals & Dev Inc filed Critical Ironshore Pharmaceuticals & Dev Inc
Publication of BR112013024401A2 publication Critical patent/BR112013024401A2/pt
Publication of BR112013024401B1 publication Critical patent/BR112013024401B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4458—Non condensed piperidines, e.g. piperocaine only substituted in position 2, e.g. methylphenidate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00—Preparations for use in therapy
BR112013024401-1A 2011-03-23 2012-03-23 Composição farmacêutica sólida oral compreendendo um ingrediente ativo estimulante do sistema nervoso central e o uso terapêutico da mesma BR112013024401B1 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161466684P 2011-03-23 2011-03-23
US61/466,684 2011-03-23
US201161561763P 2011-11-18 2011-11-18
US61/561,763 2011-11-18
US201261591129P 2012-01-26 2012-01-26
US61/591,129 2012-01-26
PCT/US2012/030472 WO2012129551A1 (en) 2011-03-23 2012-03-23 Methods and compositions for treatment of attention deficit disorder

Publications (2)

Publication Number Publication Date
BR112013024401A2 true BR112013024401A2 (pt) 2017-11-07
BR112013024401B1 BR112013024401B1 (pt) 2022-01-11

Family

ID=46879766

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013024401-1A BR112013024401B1 (pt) 2011-03-23 2012-03-23 Composição farmacêutica sólida oral compreendendo um ingrediente ativo estimulante do sistema nervoso central e o uso terapêutico da mesma

Country Status (15)

Country Link
US (1) US9028868B2 (pt)
EP (4) EP4316488A3 (pt)
JP (7) JP6043785B2 (pt)
KR (2) KR20160135373A (pt)
CN (2) CN103608004A (pt)
AU (3) AU2012230733B2 (pt)
BR (1) BR112013024401B1 (pt)
CA (1) CA2830788C (pt)
DK (3) DK2688557T3 (pt)
ES (2) ES2644942T3 (pt)
MX (3) MX357551B (pt)
PT (3) PT3272342T (pt)
SG (2) SG193587A1 (pt)
WO (1) WO2012129551A1 (pt)
ZA (1) ZA201307649B (pt)

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JP2014508812A (ja) 2014-04-10
JP2024019726A (ja) 2024-02-09
JP2018197276A (ja) 2018-12-13
CA2830788A1 (en) 2012-09-27
JP2020079322A (ja) 2020-05-28
WO2012129551A1 (en) 2012-09-27
EP4011364B1 (en) 2023-12-13
US9028868B2 (en) 2015-05-12
AU2016228307A1 (en) 2016-10-06
CN110151731A (zh) 2019-08-23
EP4316488A2 (en) 2024-02-07
JP2022066315A (ja) 2022-04-28
MX357551B (es) 2018-07-13
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ES2883589T3 (es) 2021-12-09
EP2688557A4 (en) 2014-09-24
JP6325148B2 (ja) 2018-05-16
KR101834033B1 (ko) 2018-04-13
DK2688557T3 (da) 2017-11-27
EP2688557A1 (en) 2014-01-29
EP3272342A1 (en) 2018-01-24
BR112013024401B1 (pt) 2022-01-11
CA2830788C (en) 2016-05-17
MX2021000431A (es) 2022-10-28
MX2013010920A (es) 2014-08-29
AU2012230733B2 (en) 2016-10-20
KR20160135373A (ko) 2016-11-25
PT2688557T (pt) 2017-11-23
JP2017128614A (ja) 2017-07-27
PT4011364T (pt) 2024-02-07
AU2018202002A1 (en) 2018-04-12
CN103608004A (zh) 2014-02-26
DK3272342T3 (da) 2021-06-07
EP2688557B1 (en) 2017-08-23
JP6043785B2 (ja) 2016-12-14
SG193587A1 (en) 2013-10-30
DK4011364T3 (da) 2024-03-18
JP2016117767A (ja) 2016-06-30
ES2644942T3 (es) 2017-12-01
ZA201307649B (en) 2014-06-25
EP3272342B1 (en) 2021-05-26
AU2012230733A1 (en) 2013-10-17
SG10201901167SA (en) 2019-03-28
KR20140030158A (ko) 2014-03-11
PT3272342T (pt) 2021-07-12
EP4316488A3 (en) 2024-02-28
EP4011364A1 (en) 2022-06-15
AU2018202002B2 (en) 2019-04-04
US20120276017A1 (en) 2012-11-01

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