BR112013020586A2 - Uso de células derivadas de tecido do cordão umbilical - Google Patents
Uso de células derivadas de tecido do cordão umbilicalInfo
- Publication number
- BR112013020586A2 BR112013020586A2 BR112013020586A BR112013020586A BR112013020586A2 BR 112013020586 A2 BR112013020586 A2 BR 112013020586A2 BR 112013020586 A BR112013020586 A BR 112013020586A BR 112013020586 A BR112013020586 A BR 112013020586A BR 112013020586 A2 BR112013020586 A2 BR 112013020586A2
- Authority
- BR
- Brazil
- Prior art keywords
- umbilical cord
- cord tissue
- cells
- derived cells
- lateral sclerosis
- Prior art date
Links
- 210000003954 umbilical cord Anatomy 0.000 title abstract 8
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 abstract 5
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
Classifications
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- C—CHEMISTRY; METALLURGY
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0605—Cells from extra-embryonic tissues, e.g. placenta, amnion, yolk sac, Wharton's jelly
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
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- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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- C12N2501/119—Other fibroblast growth factors, e.g. FGF-4, FGF-8, FGF-10
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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- C12N2501/20—Cytokines; Chemokines
- C12N2501/21—Chemokines, e.g. MIP-1, MIP-2, RANTES, MCP, PF-4
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
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- C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
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- C12N2502/03—Coculture with; Conditioned medium produced by non-embryonic pluripotent stem cells
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
- C12N2506/025—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells from extra-embryonic cells, e.g. trophoblast, placenta
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Pregnancy & Childbirth (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/026,995 US8491883B2 (en) | 2003-06-27 | 2011-02-14 | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
| PCT/US2012/025086 WO2012112576A1 (en) | 2011-02-14 | 2012-02-14 | Treatment of amyotrophic lateral sclerosis using umbilical derived cells |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013020586A2 true BR112013020586A2 (pt) | 2019-05-07 |
Family
ID=45755574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013020586A BR112013020586A2 (pt) | 2011-02-14 | 2012-02-14 | Uso de células derivadas de tecido do cordão umbilical |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8491883B2 (https=) |
| EP (1) | EP2675464B1 (https=) |
| JP (1) | JP6000982B2 (https=) |
| AU (1) | AU2012217782B2 (https=) |
| BR (1) | BR112013020586A2 (https=) |
| ES (1) | ES2616457T3 (https=) |
| MX (1) | MX343931B (https=) |
| PH (1) | PH12013501688A1 (https=) |
| PL (1) | PL2675464T3 (https=) |
| RU (1) | RU2612391C2 (https=) |
| SG (2) | SG192705A1 (https=) |
| WO (1) | WO2012112576A1 (https=) |
| ZA (1) | ZA201306916B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9572840B2 (en) | 2003-06-27 | 2017-02-21 | DePuy Synthes Products, Inc. | Regeneration and repair of neural tissue using postpartum-derived cells |
| US9592258B2 (en) | 2003-06-27 | 2017-03-14 | DePuy Synthes Products, Inc. | Treatment of neurological injury by administration of human umbilical cord tissue-derived cells |
| CN101668848B (zh) | 2007-04-26 | 2014-10-22 | 雷蒙特亚特特拉维夫大学有限公司 | 来自口腔粘膜的多能自体干细胞和使用方法 |
| SG174551A1 (en) | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
| US8796315B2 (en) | 2009-06-25 | 2014-08-05 | Darlene E. McCord | Methods for improved wound closure employing olivamine and human umbilical vein endothelial cells |
| KR101468123B1 (ko) * | 2012-11-27 | 2014-12-08 | 차의과학대학교 산학협력단 | 탯줄 유래 줄기세포를 포함하는 근위축 질환 개선 또는 치료용 조성물 |
| WO2014085613A1 (en) | 2012-11-30 | 2014-06-05 | Mccord Darlene E | Hydroxytyrosol and oleuropein compositions for induction of dna damage, cell death and lsd1 inhibition |
| US20140274649A1 (en) * | 2013-03-14 | 2014-09-18 | Sean Kerr | Bone Marrow Concentrator |
| US20150079062A1 (en) * | 2013-07-12 | 2015-03-19 | Patrick J. Casey | Method for harvesting, processing, and storage of proteins from the mammalian feto-placental unit and use of such proteins in compositions and medical treatment |
| EP3936609A1 (en) * | 2014-08-14 | 2022-01-12 | Avita International Ltd. | Stem cell compositions and methods of producing stem cells for therapeutic applications |
| EP4008775A1 (en) | 2015-03-04 | 2022-06-08 | Mesoblast International Sàrl | Cell culture method for mesenchymal stem cells |
| WO2017204231A1 (ja) * | 2016-05-24 | 2017-11-30 | 国立大学法人 東京大学 | 臍帯由来細胞を含む脳障害の治療剤 |
| CA3109078A1 (en) * | 2018-07-17 | 2020-01-23 | The Regents Of The University Of California | Cells differentiated from immunoengineered pluripotent cells |
| CA3133038A1 (en) * | 2019-03-14 | 2020-09-17 | Sapporo Medical University | Pharmaceutical composition for treating amyotrophic lateral sclerosis |
| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
| US12128012B2 (en) | 2020-05-15 | 2024-10-29 | University Of Kansas | Ketamine treatment for amyotrophic lateral sclerosis |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4963489A (en) | 1987-04-14 | 1990-10-16 | Marrow-Tech, Inc. | Three-dimensional cell and tissue culture system |
| US5863531A (en) | 1986-04-18 | 1999-01-26 | Advanced Tissue Sciences, Inc. | In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework |
| US5902741A (en) | 1986-04-18 | 1999-05-11 | Advanced Tissue Sciences, Inc. | Three-dimensional cartilage cultures |
| US5266480A (en) | 1986-04-18 | 1993-11-30 | Advanced Tissue Sciences, Inc. | Three-dimensional skin culture system |
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| JP5323845B2 (ja) | 2007-10-05 | 2013-10-23 | エシコン・インコーポレイテッド | ヒト臍帯組織由来細胞を用いた腎組織の修復および再建 |
| US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
| BRPI0821489A2 (pt) | 2007-12-27 | 2015-06-16 | Ethicon Inc | Tratamento de degeneração do disco intervetebral com o uso de células derivadas de tecido de cordão umbilical humano |
| BRPI0923177A2 (pt) | 2008-12-19 | 2020-08-25 | Advanced Technologies And Regenerative Medicine, Llc | usos de composições para tratar dor neuropática e espacidade, as referidas composições, e kit |
| US10179900B2 (en) | 2008-12-19 | 2019-01-15 | DePuy Synthes Products, Inc. | Conditioned media and methods of making a conditioned media |
| CN102387807A (zh) | 2008-12-19 | 2012-03-21 | 先进科技及再生医学有限责任公司 | 肺部疾病和病症的治疗 |
| JP6095893B2 (ja) | 2008-12-19 | 2017-03-15 | デピュイ・シンセス・プロダクツ・インコーポレイテッド | 傷害後の神経組織の再生および修復 |
| SG174551A1 (en) | 2009-03-26 | 2011-10-28 | Ethicon Inc | Human umbilical cord tissue cells as therapy for alzheimer' s disease |
-
2011
- 2011-02-14 US US13/026,995 patent/US8491883B2/en not_active Expired - Fee Related
-
2012
- 2012-02-14 JP JP2013553661A patent/JP6000982B2/ja not_active Expired - Fee Related
- 2012-02-14 MX MX2013009421A patent/MX343931B/es active IP Right Grant
- 2012-02-14 PL PL12705594T patent/PL2675464T3/pl unknown
- 2012-02-14 EP EP12705594.5A patent/EP2675464B1/en not_active Not-in-force
- 2012-02-14 RU RU2013141914A patent/RU2612391C2/ru active
- 2012-02-14 WO PCT/US2012/025086 patent/WO2012112576A1/en not_active Ceased
- 2012-02-14 ES ES12705594.5T patent/ES2616457T3/es active Active
- 2012-02-14 AU AU2012217782A patent/AU2012217782B2/en not_active Ceased
- 2012-02-14 PH PH1/2013/501688A patent/PH12013501688A1/en unknown
- 2012-02-14 SG SG2013060751A patent/SG192705A1/en unknown
- 2012-02-14 BR BR112013020586A patent/BR112013020586A2/pt not_active Application Discontinuation
- 2012-02-14 SG SG10201603861RA patent/SG10201603861RA/en unknown
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2013
- 2013-09-13 ZA ZA2013/06916A patent/ZA201306916B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2612391C2 (ru) | 2017-03-09 |
| EP2675464A1 (en) | 2013-12-25 |
| AU2012217782A1 (en) | 2013-09-05 |
| US8491883B2 (en) | 2013-07-23 |
| MX343931B (es) | 2016-11-28 |
| PL2675464T3 (pl) | 2017-05-31 |
| ZA201306916B (en) | 2015-04-29 |
| US20110223205A1 (en) | 2011-09-15 |
| EP2675464B1 (en) | 2016-11-16 |
| SG10201603861RA (en) | 2016-07-28 |
| PH12013501688A1 (en) | 2013-09-16 |
| RU2013141914A (ru) | 2015-03-27 |
| SG192705A1 (en) | 2013-09-30 |
| JP6000982B2 (ja) | 2016-10-05 |
| ES2616457T3 (es) | 2017-06-13 |
| JP2014509319A (ja) | 2014-04-17 |
| MX2013009421A (es) | 2014-02-27 |
| WO2012112576A1 (en) | 2012-08-23 |
| AU2012217782B2 (en) | 2016-05-26 |
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