BR112013005472A2 - 2-(r tio) 10 3 (4 r1 piperazina 1 il) propil 10h fenotiazina para tratar um amiloidopatia ou um alfa sinucleopatia ou um alfa-sinucleopatia, e método para seu diagnóstico ou pré diagnóstico - Google Patents
2-(r tio) 10 3 (4 r1 piperazina 1 il) propil 10h fenotiazina para tratar um amiloidopatia ou um alfa sinucleopatia ou um alfa-sinucleopatia, e método para seu diagnóstico ou pré diagnóstico Download PDFInfo
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102010044561.4 | 2010-09-07 | ||
| DE102010044561 | 2010-09-07 | ||
| PCT/EP2011/064893 WO2012031941A2 (de) | 2010-09-07 | 2011-08-30 | 2-(R²-THIO)-10-[3-(4-R1-PIPERAZIN-1-YL)PROPYL]-10H-PHENOTHIAZINE ZUR BEHANDLUNG EINER β-AMYLOIDOPATHIE ODER ALPHA-SYNUCLEOPATHIE SOWIE VERFAHREN ZU DEREN DIAGNOSE ODER PRÄDIAGNOSE |
Publications (1)
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| BR112013005472A2 true BR112013005472A2 (pt) | 2020-11-10 |
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| BR112013005472-7A BR112013005472A2 (pt) | 2010-09-07 | 2011-08-30 | 2-(r tio) 10 3 (4 r1 piperazina 1 il) propil 10h fenotiazina para tratar um amiloidopatia ou um alfa sinucleopatia ou um alfa-sinucleopatia, e método para seu diagnóstico ou pré diagnóstico |
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| EP (3) | EP2693216B1 (https=) |
| JP (2) | JP6084924B2 (https=) |
| CN (2) | CN103237802B (https=) |
| BR (1) | BR112013005472A2 (https=) |
| CA (2) | CA2811454C (https=) |
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| ES (2) | ES2605705T3 (https=) |
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| PL (2) | PL2614060T3 (https=) |
| RU (2) | RU2016118021A (https=) |
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| JP7073330B2 (ja) | 2016-07-25 | 2022-05-23 | ウィスタ ラボラトリーズ リミテッド | ジアミノフェノチアジンの投与及び投与量 |
| FI4385512T3 (fi) | 2018-07-26 | 2026-01-12 | Taurx Therapeutics Man Ltd | Diaminofenotiatsiinien optimoitu annostus populaatioille |
| US20230192748A1 (en) * | 2020-03-16 | 2023-06-22 | Doublerainbow Biosciences Inc. | Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug |
| EP4460311A1 (en) * | 2022-01-04 | 2024-11-13 | Immungenetics AG | Specific dosage of phenothiazine compounds for use in treatment or prevention of alzheimer's dementia |
| EP4605754A1 (en) * | 2022-10-18 | 2025-08-27 | Immungenetics AG | Identifying a subject suffering from alzheimer's dementia or being at risk of developing alzheimer's dementia |
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| CH365379A (de) * | 1956-04-18 | 1962-11-15 | Sandoz Ag | Verfahren zur Herstellung von neuen, in 3-Stellung mit einer einwertigen Schwefelfunktion substituierten Phenothiazinen |
| BE568701A (https=) * | 1957-06-18 | |||
| US3621097A (en) * | 1970-03-30 | 1971-11-16 | Jan Marcel Didier Aron Samuel | Method and compositions for treatment of mental illness |
| US4471116A (en) * | 1982-07-28 | 1984-09-11 | Hoffmann-La Roche Inc. | Substituted (10H-phenothiazin-10-L)-propyl-1-piperazines |
| US6566368B2 (en) * | 1994-04-22 | 2003-05-20 | Pentech Pharmaceuticals, Inc. | Apomorphine-containing dosage form for ameliorating male erectile dysfunction |
| AU708682B2 (en) * | 1994-08-08 | 1999-08-12 | Albert Einstein College Of Medicine Of Yeshiva University | Methods for treating and/or preventing Alzheimer's disease using phenothiazines and/or thioxanthenes |
| DE4430091A1 (de) * | 1994-08-25 | 1996-02-29 | Bayer Ag | Verwendung von N-substituierten Phenothiazinen |
| ES2272911T3 (es) * | 2003-04-25 | 2007-05-01 | Neurofit Sas | Uso de derivados de fenotiazina piperazina en la fabricacion de un medicamento con efectos neuroprotector y/o neurotroficos sobre cns y/o pns. |
| DE102005014142B4 (de) * | 2005-03-23 | 2006-11-09 | Hennig Arzneimittel Gmbh & Co. Kg | Pelletförmige Retardzubereitung gegen Schwindel |
| WO2007062862A2 (en) * | 2005-12-02 | 2007-06-07 | Ludwig Maximilians Universität München | Use of calmodulin inhibitors for the treatment of neurodegenerative disorders |
| MY148145A (en) * | 2006-07-11 | 2013-03-15 | Wista Lab Ltd | Methods of synthesis and/or purification of diaminophenothiazinium compounds |
| RU2500685C2 (ru) * | 2006-11-10 | 2013-12-10 | Кара Терапеутикс, Инк | Синтетические пептидные амиды |
| GB0701970D0 (en) * | 2007-02-01 | 2007-03-14 | Wilson Stuart | Treatment of protein aggregation diseases |
| TW200848063A (en) * | 2007-04-23 | 2008-12-16 | Combinatorx Inc | Methods and compositions for the treatment of neurodegenerative disorders |
| PL2282778T3 (pl) * | 2008-04-29 | 2017-08-31 | Pharnext | Nowe podejścia terapeutyczne do leczenia choroby alzheimera i powiązanych zaburzeń poprzez modulację angiogenezy |
| DK2282779T3 (da) * | 2008-04-29 | 2013-05-27 | Pharnext | Nye terapeutiske fremgangsmåder til behandling af alzheimer sygdom og beslægtede lidelser gennem en modulation af cellestress-respons |
| WO2009133128A1 (en) * | 2008-04-29 | 2009-11-05 | Pharnext | Combination compositions for treating alzheimer disease and related disorders with zonisamide and acamprosate |
| US9399032B2 (en) * | 2009-05-14 | 2016-07-26 | The General Hospital Corporation | Methods and compositions for treating degenerative and ischemic disorders |
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