BR112013002859A2 - sistema e aparelho para tratamento de células - Google Patents

sistema e aparelho para tratamento de células

Info

Publication number
BR112013002859A2
BR112013002859A2 BR112013002859A BR112013002859A BR112013002859A2 BR 112013002859 A2 BR112013002859 A2 BR 112013002859A2 BR 112013002859 A BR112013002859 A BR 112013002859A BR 112013002859 A BR112013002859 A BR 112013002859A BR 112013002859 A2 BR112013002859 A2 BR 112013002859A2
Authority
BR
Brazil
Prior art keywords
cell treatment
treatment system
cells
present
components
Prior art date
Application number
BR112013002859A
Other languages
English (en)
Other versions
BR112013002859B1 (pt
Inventor
William G Austen Jr
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Publication of BR112013002859A2 publication Critical patent/BR112013002859A2/pt
Publication of BR112013002859B1 publication Critical patent/BR112013002859B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0653Adipocytes; Adipose tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/145Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14526Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00Means for pre-treatment of biological substances
    • C12M45/02Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Vascular Medicine (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Surgical Instruments (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

sistema e aparelho para tratamento de células. a presente invenção refere-se a sistemas e aparelho para aperfeiçoar a qualidade e viabilidade de material biológico, tais como células adiposas, células basais ou outras células coletadas ou componentes biológico, por tratamento do material biológico com agentes de estabilização/reparo de membrana ou similares e/ou remoção mecânica dos componentes, tais como impurezas e/ou excesso de agentes de de tratamento. a presente invenção refere-se, ainda, a ssitemas e aparelhos para transplantar tecido, tal como tecido adiposo.
BR112013002859-9A 2010-08-06 2011-08-05 Método e aparelho para tratamento de células BR112013002859B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37140010P 2010-08-06 2010-08-06
US61/371,400 2010-08-06
PCT/US2011/046752 WO2012019103A2 (en) 2010-08-06 2011-08-05 System and apparatus for cell treatment

Publications (2)

Publication Number Publication Date
BR112013002859A2 true BR112013002859A2 (pt) 2016-05-31
BR112013002859B1 BR112013002859B1 (pt) 2020-10-06

Family

ID=45560093

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013002859-9A BR112013002859B1 (pt) 2010-08-06 2011-08-05 Método e aparelho para tratamento de células

Country Status (7)

Country Link
US (1) US10184110B2 (pt)
EP (2) EP3530741B1 (pt)
JP (1) JP6072684B2 (pt)
KR (1) KR101809301B1 (pt)
CN (2) CN103153376B (pt)
BR (1) BR112013002859B1 (pt)
WO (1) WO2012019103A2 (pt)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11660317B2 (en) 2004-11-08 2023-05-30 The Johns Hopkins University Compositions comprising cardiosphere-derived cells for use in cell therapy
JP5795961B2 (ja) 2008-10-21 2015-10-14 ザ ジェネラル ホスピタル コーポレイション 細胞移植
US9999702B2 (en) 2010-04-09 2018-06-19 Kci Licensing Inc. Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds
US10184110B2 (en) 2010-08-06 2019-01-22 The General Hospital Corporation System and apparatus for cell treatment
US8632498B2 (en) 2011-02-11 2014-01-21 TauTona Group Research and Development Company, L.L.C. Tissue transfer systems
CA2827034C (en) 2011-02-11 2019-02-26 TauTona Group Research and Development Company, L.L.C. Devices and methods for tissue transfer
US9409175B2 (en) * 2012-02-28 2016-08-09 Arkray, Inc. Mixing apparatus
CA2875363A1 (en) 2012-05-30 2013-12-05 Lifecell Corporation Device for harvesting, processing, and transferring adipose tissue
JP2013251935A (ja) * 2012-05-30 2013-12-12 Denso Corp アクチュエータ
WO2013184527A1 (en) * 2012-06-05 2013-12-12 Capricor, Inc. Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy
EP2872191B1 (en) 2012-07-13 2019-08-07 LifeCell Corporation Methods for improved treatment of adipose tissue
US10549112B2 (en) 2012-07-20 2020-02-04 The General Hospital Corporation Apparatus for tissue irradiation and methods and kits utilizing the same
US10292381B2 (en) 2012-07-20 2019-05-21 The General Hospital Corporation Vessel treatment systems, methods, and kits
WO2014015274A1 (en) 2012-07-20 2014-01-23 The General Hospital Corporation Methods for tissue passivation
CA2881394C (en) 2012-08-13 2024-05-14 Cedars-Sinai Medical Center Exosomes and micro-ribonucleic acids for tissue regeneration
EP3075841B1 (en) 2012-09-06 2021-03-10 GID BIO, Inc. Tissue processing apparatus and method for processing adipose tissue
WO2014052376A1 (en) 2012-09-26 2014-04-03 Lifecell Corporation Processed adipose tissue
GB2509780B (en) * 2013-01-15 2019-08-28 Brightwake Ltd Fat Processing Device
WO2014164815A2 (en) * 2013-03-12 2014-10-09 Allergan, Inc. Adipose tissue combinations, devices, and uses thereof
WO2014178438A1 (ja) * 2013-05-02 2014-11-06 Saeki Masanori 毛髪再生用の細胞製剤
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
AU2014290513B2 (en) 2013-07-18 2017-07-27 The General Hospital Corporation Vessel treatment systems, methods, and kits
ITMO20130228A1 (it) 2013-08-02 2015-02-03 Biomed Device Srl Sistema e metodo per aliquotare grasso da liposuzione ai fini dell'uso e della crioconservazione
US9248384B2 (en) 2013-10-02 2016-02-02 Allergan, Inc. Fat processing system
CN103598901A (zh) * 2013-10-24 2014-02-26 苏雪莲 一种脂肪移植装置
US20150314284A1 (en) * 2014-05-02 2015-11-05 Francesca Dagny TEKULA Specimen container for biological materials
EP3137139A1 (en) 2014-05-02 2017-03-08 Lifecell Corporation Injection sensor with feedback mechanism
US20170188572A1 (en) 2014-05-02 2017-07-06 Francesca Dagny TEKULA Specimen container for biological materials
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
US10279325B1 (en) * 2014-09-04 2019-05-07 Black Tie Medical, Inc. System and method for harvesting emulsified fat and stem cells
AU2015327812B2 (en) 2014-10-03 2021-04-15 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy
AU2016219956B2 (en) 2015-02-19 2020-08-13 Lifecell Corporation Tissue processing device and associated systems and methods
CA2976544A1 (en) 2015-03-10 2016-09-15 Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company Multiple needle injector
US10130740B2 (en) * 2015-03-17 2018-11-20 Wells Johnson Company Pressure control during processing of adipose tissue
WO2016183135A1 (en) 2015-05-12 2016-11-17 Parker Isaac Instruments, Llc Pathologic staging compression apparatus and methods
US9861939B2 (en) 2015-10-02 2018-01-09 Lawrence Livermore National Security, Llc Filtration device for rapid separation of biological particles from complex matrices
BR112018008059A2 (pt) 2015-10-21 2018-10-23 Lifecell Corp sistemas e métodos para controle de dispositivo médico
ES2775597T3 (es) 2015-10-21 2020-07-27 Lifecell Corp Sistemas y métodos para la gestión de tubos
WO2017112755A1 (en) 2015-12-22 2017-06-29 Lifecell Corporation Syringe filling device for fat transfer
US11253551B2 (en) 2016-01-11 2022-02-22 Cedars-Sinai Medical Center Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction
KR102232054B1 (ko) 2016-04-08 2021-03-26 알레간 인코포레이티드 흡인 및 주입 디바이스
EP3239286A1 (en) 2016-04-26 2017-11-01 Ludwig Boltzmann Gesellschaft Non-enzymatic method and milling device
WO2017189918A1 (en) * 2016-04-27 2017-11-02 Hagarty Sarah Elizabeth A closed loop system for direct harvest and transfer for high volume fat grafting
US20170312403A1 (en) 2016-04-27 2017-11-02 Sarah Elizabeth Hagarty Simple Closed Loop System for Direct Harvest and Transfer for High Volume Fat Grafting
US11351200B2 (en) 2016-06-03 2022-06-07 Cedars-Sinai Medical Center CDC-derived exosomes for treatment of ventricular tachyarrythmias
BR112019003871A2 (pt) 2016-08-30 2019-07-16 Lifecell Corp sistemas e métodos para controle de dispositivo médico
WO2018057542A1 (en) 2016-09-20 2018-03-29 Cedars-Sinai Medical Center Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders
WO2018111550A1 (en) * 2016-12-12 2018-06-21 Werd, Llc A syringe for processing fat grafts and related methods
JP7336769B2 (ja) 2017-04-19 2023-09-01 シーダーズ―シナイ メディカル センター 骨格筋ジストロフィーを治療する方法及び組成物
WO2018204929A1 (en) * 2017-05-05 2018-11-08 Hagarty Sarah Elizabeth A system for the harvest and transfer for high volume fat grafting using a centrifugal pump
CN107174678B (zh) * 2017-06-30 2023-07-18 杨忠 一种自体脂肪采集、净化及移植装置
CN107641595B (zh) * 2017-08-15 2023-03-21 中国人民解放军第二军医大学第二附属医院 关节镜下获取无菌膝髌下脂肪垫组织提取装置及方法
CA3073811A1 (en) 2017-08-28 2019-03-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Methods and devices for use in treatment of plantar fasciitis and fat grafting
US20190185814A1 (en) * 2017-12-14 2019-06-20 Lifecell Corporation Device and methods for tissue processing
WO2019126068A1 (en) 2017-12-20 2019-06-27 Cedars-Sinai Medical Center Engineered extracellular vesicles for enhanced tissue delivery
CN109876201A (zh) * 2019-03-07 2019-06-14 杭州百桥医疗技术有限公司 一种自体脂肪抽吸、纯化、精准注射与安全监测系统
CN109925014B (zh) * 2019-04-03 2024-03-22 北京阿拉布丁生物科技有限公司 一种脂肪提纯装置
KR102075422B1 (ko) * 2019-04-05 2020-02-11 주식회사 이뮤니스바이오 세포 회수용 튜브 및 이를 포함하는 주사 키트
CN114364784B (zh) * 2019-09-30 2024-02-02 泰尔茂株式会社 试样的粉碎方法
KR102091151B1 (ko) * 2019-10-08 2020-03-20 주식회사 로킷헬스케어 당뇨병성 족부병증 환자 맞춤형 피부 재생 시트의 제조방법 및 이를 이용하여 제조된 당뇨병성 족부병증 환자 맞춤형 피부 재생 시트
IT201900022350A1 (it) * 2019-12-04 2021-06-04 Hydra S R L Dispositivo di frammentazione di tessuti in ambiente chiuso sterile con procedura asettica e suo metodo
US20210332315A1 (en) * 2020-04-22 2021-10-28 Ben M. Khalaj Filtration-centrifuge tube apparatus for harvesting adipose derived stem cells
CN113116414A (zh) * 2021-04-22 2021-07-16 任学会 一种自体脂肪填充移植使用的全封闭系统
US11679198B2 (en) 2021-04-28 2023-06-20 Chopra Gryskiewicz, LLC System and related methods for fat harvesting
KR102593281B1 (ko) * 2021-07-05 2023-10-24 주식회사 바이오솔루션 스페로이드형 세포치료제 이식용 주입장치
CN113583950A (zh) * 2021-08-06 2021-11-02 合肥滴碧云生物科技有限公司 一种制备干细胞活性因子的方法及其应用
FR3131217B1 (fr) * 2021-12-23 2023-12-22 Groupe Sebbin Dispositif de collecte de tissu à réservoir de taille modulable
US20240182837A1 (en) * 2022-12-01 2024-06-06 Sientra, Inc. Lipoaspirate wash system and method
JP7562090B1 (ja) 2023-10-19 2024-10-07 国立大学法人高知大学 マーカー、マーカー留置具及びマーカー検出装置

Family Cites Families (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212071A (en) 1988-04-01 1993-05-18 The Johns Hopkins University Nucleic acids encoding a human C3b/C4b receptor (CR1)
US5981481A (en) 1974-12-06 1999-11-09 The Johns Hopkins University Human C3b/C4b receptor (CR1)
IL89790A (en) 1988-04-01 2002-05-23 Johns Hopking University Sequences of nucleic acids encoding and cells producing CR1 protein and methods for its production and purification
US5256642A (en) 1988-04-01 1993-10-26 The Johns Hopkins University Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof
DK0427247T3 (da) 1989-11-09 1998-09-28 Asta Medica Ag Lægemiddel indeholdende R-alpha- lipoinsyre eller S-alphalipoinsyre som aktiv bestanddel
US5052999A (en) 1990-01-29 1991-10-01 Klein Jeffrey A Liposuction method and apparatus
AU662146B2 (en) 1991-03-19 1995-08-24 Cytrx Corporation Polyoxypropylene/polyoxyethylene copolymers with improved biological activity
US5470568A (en) 1992-02-13 1995-11-28 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for cell repair
US5605687A (en) 1992-05-15 1997-02-25 Arch Development Corporation Methods and compositions of a polymer (poloxamer) for repair of electrical injury
US5569670A (en) 1992-06-05 1996-10-29 Asta Medica Aktiengesellschaft Combination medications containing alpha-lipoic acid and related
DE4229914A1 (de) 1992-09-08 1994-03-10 Basf Ag Verbessertes Verfahren zur Herstellung von R/S-Ï-Liponsäure oder R/S-â-Liponsäure
WO1995001332A1 (fr) 1993-07-01 1995-01-12 Nkk Corporation Derive d'arylsulfonamide et composition pharmaceutique le contenant
DE4343593C2 (de) 1993-12-21 1998-05-20 Asta Medica Ag Verwendung von R-(+)-alpha-Liponsäure, R-(-)-Dihydroliponsäure oder der Metabolite sowie deren Salze, Ester, Amide zur Behandlung kompensierter und dekompensierter Insulinresistenz
DE4427079C2 (de) 1994-07-30 2002-12-19 Viatris Gmbh Verfahren zur Racemisierung von Enantiomeren der alpha-Liponsäure
US5716404A (en) 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5681561A (en) 1995-06-07 1997-10-28 Life Medical Sciences, Inc. Compositions and methods for improving autologous fat grafting
US5709868A (en) 1995-09-20 1998-01-20 Perricone; Nicholas V. Lipoic acid in topical compositions
US6752999B2 (en) 1995-09-20 2004-06-22 Nicholas V. Perricone Method of skin care and/or treatment using lipoic acid
US6328712B1 (en) 1996-02-28 2001-12-11 Smisson-Cartledge Biomedical Corporation Rapid infusion system
US5879876A (en) 1997-03-24 1999-03-09 Lifenet Continuous-multi-step dilution process and apparatus, for the removal of cryoprotectants from cryopreserved tissues
US7220557B2 (en) 1997-04-24 2007-05-22 Human Genome Sciences, Inc. METH1 polynucleotides
US5965618A (en) 1997-11-17 1999-10-12 Perricone; Nicholas V. Treatment of scar tissue using lipoic acid
US6365623B1 (en) 1997-11-17 2002-04-02 Nicholas V. Perricone Treatment of acne using lipoic acid
US6090842A (en) 1998-03-10 2000-07-18 The Regents Of The University Of California Lipoic acid analogs
US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
WO1999061440A1 (en) 1998-05-26 1999-12-02 Smithkline Beecham Corporation Novel substituted imidazole compounds
BR9914789A (pt) 1998-10-26 2001-10-02 Univ New York State Res Found Derivados de ácido lipóico e seus usos no tratamento de doença
EP1224322A2 (en) 1999-02-22 2002-07-24 Variagenics, Inc. Gene sequence variations with utility in determining the treatment of disease
US6204288B1 (en) 1999-03-08 2001-03-20 The University Of Mississippi 1,2-dithiolane derivatives
AR042572A1 (es) 1999-04-02 2005-06-29 Sod Conseils Rech Applic Derivados de acido lipoico, procedimiento para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y utilizacion de dichos derivados para la preparacion de los referidos medicamentos
US6103255A (en) 1999-04-16 2000-08-15 Rutgers, The State University Porous polymer scaffolds for tissue engineering
AU5045900A (en) 1999-05-25 2000-12-12 Beth Israel Deaconess Medical Center Meth1 and meth2 polynucleotides and polypeptides
US6316247B1 (en) * 1999-06-15 2001-11-13 University Of Pittsburgh System and method for refining liposuctioned adipose tissue
CA2387685A1 (en) 1999-10-27 2001-05-03 Human Genome Sciences, Inc. Stanniocalcin proteins and nucleic acids and methods based thereon
US6673033B1 (en) * 1999-11-24 2004-01-06 Medrad, Inc. Injectors, injector systems and injector control
WO2001093824A1 (en) 2000-06-06 2001-12-13 Basf Aktiengesellschaft Use of an (r)-enantiomer of lipoic acid in cosmetics and dermatologicals
WO2002016557A2 (en) 2000-08-21 2002-02-28 Rice University Tissue engineering scaffolds promoting matrix protein production
US6277842B1 (en) 2000-10-17 2001-08-21 James Alexander Carthron Dietary supplemental method for fat and weight reduction
US7227007B2 (en) 2000-12-28 2007-06-05 Asahi Kasei Pharma Corporation NF-κB activating gene
CA2440058A1 (en) 2001-03-07 2002-09-19 Bristol-Myers Squibb Company Polynucleotide encoding a novel human g-protein coupled receptor, hgprbmy27
EP1377597A4 (en) 2001-03-22 2005-02-09 Bristol Myers Squibb Co POLYNUCLEOTIDE CODING FOR A NEW MEMBER OF THE IMMUNOGLOBULIN SUPERFAMILY, APEX4, AND ITS VARIATIONS AND SPICE VARIANTS
WO2002076288A2 (en) 2001-03-27 2002-10-03 Board Of Regents The University Of Texas System Biodegradable, electrically conductiong polymer for tissue engineering applications
US20040086896A1 (en) 2001-04-19 2004-05-06 Julie Carman Polynucleotides and polypeptides associated with the NF-kB pathway
US20030224486A1 (en) 2001-04-19 2003-12-04 Julie Carman Polynucleotides and polypeptides associated with the NF-kB pathway
JP2004527573A (ja) 2001-04-24 2004-09-09 パーデュー・リサーチ・ファウンデーション 哺乳類の神経組織損傷の治療のための方法及び組成物
US20030103913A1 (en) 2001-05-07 2003-06-05 Nathoo Salim A. Metal activated tooth whitening compositions
US7504481B2 (en) 2001-08-02 2009-03-17 Bristol-Meyers Squibb Company TRP channel family member, LTRPC3 polypeptides
AU2002326497A1 (en) 2001-08-02 2003-02-17 Bristol-Myers Squibb Company Polynucleotide encoding a novel trp channel family member, ltrpc3, and splice variants thereof
US20040116350A1 (en) 2001-09-17 2004-06-17 Paul Wentworth Jr Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies
US7452532B2 (en) * 2001-09-30 2008-11-18 Scicotec Gmbh Transluminal application of adult stem cells for body organ tissue repair
AU2002357135C1 (en) 2001-12-07 2009-01-22 Macropore Biosurgery, Inc. Systems and methods for treating patients with processed lipoaspirate cells
US7514075B2 (en) * 2001-12-07 2009-04-07 Cytori Therapeutics, Inc. Systems and methods for separating and concentrating adipose derived stem cells from tissue
US7651684B2 (en) * 2001-12-07 2010-01-26 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in augmenting autologous fat transfer
AU2003226131A1 (en) 2002-03-28 2003-10-13 Bristol-Myers Squibb Company Novel human cell surface protein with immunoglobulin folds, bgs-19
AU2003222109A1 (en) 2002-03-29 2003-10-13 Bristol-Myers Squibb Company Polynucleotides encoding novel two splice variants of a human cell surface protein with immunologobulin folds, bgs5g and bgs5i
US20040087543A1 (en) 2002-04-25 2004-05-06 Zachary Shriver Methods and products for mucosal delivery
AU2003299496A1 (en) 2002-05-14 2004-05-25 Bristol-Myers Squibb Company Polynucleotide encoding novel human g-protein coupled receptors, and splice variants thereof
WO2003106663A1 (ja) 2002-06-18 2003-12-24 エーザイ株式会社 遺伝子治療用初代培養脂肪細胞
US20040204576A1 (en) 2002-07-02 2004-10-14 Donald Jackson Polynucleotides encoding a novel human phosphatase, BMY_HPP13
US7550155B2 (en) 2002-07-29 2009-06-23 Transform Pharmaceuticals Inc. Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
EP1539282A2 (en) * 2002-08-06 2005-06-15 GenVec, Inc. Improved injection system
US20040101959A1 (en) 2002-11-21 2004-05-27 Olga Marko Treatment of tissue with undifferentiated mesenchymal cells
AU2003295824A1 (en) 2002-11-22 2004-06-18 Incyte Corporation Cell adhesion and extracellular matrix proteins
KR100473568B1 (ko) 2003-01-25 2005-03-10 이희영 밀폐형 지방이식 시스템
US20060184101A1 (en) * 2003-04-21 2006-08-17 Ravi Srinivasan Microjet devices and methods for drug delivery
CN1842589B (zh) 2003-06-25 2012-04-25 马克罗珀尔生物外科公司 用于从组织分离并且浓缩再生细胞的系统和方法
US20040265345A1 (en) 2003-06-30 2004-12-30 Perricone Nicholas V. Treatment of skin damage using acetyl carnitine and lipoic acid
FR2856891B1 (fr) 2003-07-04 2007-09-07 Stem Alpha Milieu de conservation d'organes, de tissus biologiques ou de cellules vivantes
US20050118632A1 (en) 2003-11-06 2005-06-02 Jian Chen Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b
WO2005046438A2 (en) 2003-11-06 2005-05-26 Pluromed, Inc. Internal clamp for surgical procedures
US20050208095A1 (en) 2003-11-20 2005-09-22 Angiotech International Ag Polymer compositions and methods for their use
US20050124073A1 (en) * 2003-12-09 2005-06-09 Entire Interest Fat collection and preparation system and method
US7087369B2 (en) 2003-12-17 2006-08-08 The Regents Of The University Of California Cornea preservation medium
EP1702058B1 (en) 2004-01-08 2012-06-13 North Carolina State University Methods and devices for microencapsulation of cells
US7588732B2 (en) 2004-03-30 2009-09-15 Genesis Biosystems, Inc. Autologus tissue harvesting and irrigation device
WO2005099758A2 (en) 2004-04-17 2005-10-27 The Board Of Trustees The Leland Standford Junior University Injectable bioartificial tissue matrix
GB0414825D0 (en) 2004-07-02 2004-08-04 Biostatus Ltd Gel formulations and uses thereof
EP1804813A4 (en) 2004-09-27 2011-09-07 Vical Inc FORMULATIONS AND METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES
WO2006044738A2 (en) 2004-10-18 2006-04-27 Maroon Biotech Corporation Methods and compositions for treatment of free radical injury
US20060127384A1 (en) 2004-12-09 2006-06-15 Sergio Capaccioli Coenzyme Q10 as antiapoptotic agent
US7789872B2 (en) * 2005-03-23 2010-09-07 Shippert Ronald D Tissue transplantation method and apparatus
US7794449B2 (en) * 2005-03-23 2010-09-14 Shippert Ronald D Tissue transplantation method and apparatus
CN105394748A (zh) 2005-04-06 2016-03-16 雀巢产品技术援助有限公司 从营养方面改善葡萄糖控制和胰岛素作用的方法和组合物
WO2007005668A2 (en) 2005-06-30 2007-01-11 Amgen Inc. Bis-aryl kinase inhibitors and their use in the treatment of inflammation, angiogenesis and cancer
WO2007009285A1 (en) 2005-07-21 2007-01-25 Eth Zurich Cryo-conservation medium for in-vitro cultured cells
US9265792B2 (en) 2005-11-16 2016-02-23 Patricia A. Riley Integument cell regeneration formulation
EP1965811A4 (en) * 2005-11-21 2011-01-19 Nicast Ltd DEVICE AND METHOD FOR CELL GRAFT
EP1988159B1 (en) 2006-01-13 2014-03-05 Two Cells Co., Ltd. Additive for culture medium for use in serum-free culture of animal cell, kit, and use of the additive or kit
KR100764640B1 (ko) * 2006-03-08 2007-10-10 세원셀론텍(주) 지방조직 수복용 키트
KR100683280B1 (ko) * 2006-07-11 2007-02-16 메디칸(주) 지방 흡입 및 이식용 주사기
US7960098B2 (en) 2007-07-12 2011-06-14 Warsaw Orthoperic, Inc. Methods and compositions for the preservation of cells and tissues
US7892724B2 (en) 2007-07-12 2011-02-22 Warsaw Orthopedic, Inc Method for enhancing the viability of mammalian cells, tissues and organs using a solution comprising two low molecular weight PEGs
WO2009055610A1 (en) * 2007-10-26 2009-04-30 Cytori Therapeutics, Inc. Syringe system for controlled delivery or removal of material
BRPI0908087A2 (pt) 2008-02-11 2015-08-25 Univ Johns Hopkins Composições e métodos para implante de tecido adipose e produtos de tecido adiposo
JP2010063441A (ja) 2008-09-12 2010-03-25 Olympus Corp 脂肪除去方法と生体組織処理方法
JP5795961B2 (ja) 2008-10-21 2015-10-14 ザ ジェネラル ホスピタル コーポレイション 細胞移植
DE102009022346B4 (de) 2009-05-15 2011-05-19 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Automatisches Abtrennen von Fettgewebe
US8790519B2 (en) * 2009-06-16 2014-07-29 Biomet Biologics, Llc Liquid separation from adipose tissue
CA2768613A1 (en) 2009-07-20 2011-01-27 The General Hospital Corporation D/B/A Massachusetts General Hospital Methods and compositions for improving the viability of cryopreserved cells
CN201492455U (zh) * 2009-09-25 2010-06-02 金哲 用于脂肪抽取、分离和移植的装置
WO2011059733A2 (en) 2009-10-29 2011-05-19 The General Hospital Corporation D/B/A Massachusetts General Hospital Use of lipoic acid in cell transplantation
BR112012029465A2 (pt) 2010-05-21 2017-03-01 Sound Surgical Tech Llc dispositivo ultrassônico para retirada de tecido adiposo
US10184110B2 (en) 2010-08-06 2019-01-22 The General Hospital Corporation System and apparatus for cell treatment

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KR101809301B1 (ko) 2018-01-18
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US10184110B2 (en) 2019-01-22
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CN103153376B (zh) 2018-04-20
EP3530741A1 (en) 2019-08-28
WO2012019103A8 (en) 2012-12-27
BR112013002859B1 (pt) 2020-10-06
CN108504539B (zh) 2021-11-02
EP2601299A2 (en) 2013-06-12
EP2601299B1 (en) 2019-04-24
CN103153376A (zh) 2013-06-12
KR20140023247A (ko) 2014-02-26
EP3530741B1 (en) 2021-04-07
CN108504539A (zh) 2018-09-07
US20130158515A1 (en) 2013-06-20

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