BR112013002859A2 - sistema e aparelho para tratamento de células - Google Patents
sistema e aparelho para tratamento de célulasInfo
- Publication number
- BR112013002859A2 BR112013002859A2 BR112013002859A BR112013002859A BR112013002859A2 BR 112013002859 A2 BR112013002859 A2 BR 112013002859A2 BR 112013002859 A BR112013002859 A BR 112013002859A BR 112013002859 A BR112013002859 A BR 112013002859A BR 112013002859 A2 BR112013002859 A2 BR 112013002859A2
- Authority
- BR
- Brazil
- Prior art keywords
- cell treatment
- treatment system
- cells
- present
- components
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
- A61M5/14526—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons the piston being actuated by fluid pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
- A61M5/172—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
- A61M5/1723—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M45/00—Means for pre-treatment of biological substances
- C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Fluid Mechanics (AREA)
- Physics & Mathematics (AREA)
- Mechanical Engineering (AREA)
- Molecular Biology (AREA)
- Sustainable Development (AREA)
- Materials For Medical Uses (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Surgical Instruments (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
sistema e aparelho para tratamento de células. a presente invenção refere-se a sistemas e aparelho para aperfeiçoar a qualidade e viabilidade de material biológico, tais como células adiposas, células basais ou outras células coletadas ou componentes biológico, por tratamento do material biológico com agentes de estabilização/reparo de membrana ou similares e/ou remoção mecânica dos componentes, tais como impurezas e/ou excesso de agentes de de tratamento. a presente invenção refere-se, ainda, a ssitemas e aparelhos para transplantar tecido, tal como tecido adiposo.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37140010P | 2010-08-06 | 2010-08-06 | |
US61/371,400 | 2010-08-06 | ||
PCT/US2011/046752 WO2012019103A2 (en) | 2010-08-06 | 2011-08-05 | System and apparatus for cell treatment |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112013002859A2 true BR112013002859A2 (pt) | 2016-05-31 |
BR112013002859B1 BR112013002859B1 (pt) | 2020-10-06 |
Family
ID=45560093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013002859-9A BR112013002859B1 (pt) | 2010-08-06 | 2011-08-05 | Método e aparelho para tratamento de células |
Country Status (7)
Country | Link |
---|---|
US (1) | US10184110B2 (pt) |
EP (2) | EP3530741B1 (pt) |
JP (1) | JP6072684B2 (pt) |
KR (1) | KR101809301B1 (pt) |
CN (2) | CN103153376B (pt) |
BR (1) | BR112013002859B1 (pt) |
WO (1) | WO2012019103A2 (pt) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11660317B2 (en) | 2004-11-08 | 2023-05-30 | The Johns Hopkins University | Compositions comprising cardiosphere-derived cells for use in cell therapy |
JP5795961B2 (ja) | 2008-10-21 | 2015-10-14 | ザ ジェネラル ホスピタル コーポレイション | 細胞移植 |
US9999702B2 (en) | 2010-04-09 | 2018-06-19 | Kci Licensing Inc. | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
US10184110B2 (en) | 2010-08-06 | 2019-01-22 | The General Hospital Corporation | System and apparatus for cell treatment |
US8632498B2 (en) | 2011-02-11 | 2014-01-21 | TauTona Group Research and Development Company, L.L.C. | Tissue transfer systems |
CA2827034C (en) | 2011-02-11 | 2019-02-26 | TauTona Group Research and Development Company, L.L.C. | Devices and methods for tissue transfer |
US9409175B2 (en) * | 2012-02-28 | 2016-08-09 | Arkray, Inc. | Mixing apparatus |
CA2875363A1 (en) | 2012-05-30 | 2013-12-05 | Lifecell Corporation | Device for harvesting, processing, and transferring adipose tissue |
JP2013251935A (ja) * | 2012-05-30 | 2013-12-12 | Denso Corp | アクチュエータ |
WO2013184527A1 (en) * | 2012-06-05 | 2013-12-12 | Capricor, Inc. | Optimized methods for generation of cardiac stem cells from cardiac tissue and their use in cardiac therapy |
EP2872191B1 (en) | 2012-07-13 | 2019-08-07 | LifeCell Corporation | Methods for improved treatment of adipose tissue |
US10549112B2 (en) | 2012-07-20 | 2020-02-04 | The General Hospital Corporation | Apparatus for tissue irradiation and methods and kits utilizing the same |
US10292381B2 (en) | 2012-07-20 | 2019-05-21 | The General Hospital Corporation | Vessel treatment systems, methods, and kits |
WO2014015274A1 (en) | 2012-07-20 | 2014-01-23 | The General Hospital Corporation | Methods for tissue passivation |
CA2881394C (en) | 2012-08-13 | 2024-05-14 | Cedars-Sinai Medical Center | Exosomes and micro-ribonucleic acids for tissue regeneration |
EP3075841B1 (en) | 2012-09-06 | 2021-03-10 | GID BIO, Inc. | Tissue processing apparatus and method for processing adipose tissue |
WO2014052376A1 (en) | 2012-09-26 | 2014-04-03 | Lifecell Corporation | Processed adipose tissue |
GB2509780B (en) * | 2013-01-15 | 2019-08-28 | Brightwake Ltd | Fat Processing Device |
WO2014164815A2 (en) * | 2013-03-12 | 2014-10-09 | Allergan, Inc. | Adipose tissue combinations, devices, and uses thereof |
WO2014178438A1 (ja) * | 2013-05-02 | 2014-11-06 | Saeki Masanori | 毛髪再生用の細胞製剤 |
US20140350516A1 (en) | 2013-05-23 | 2014-11-27 | Allergan, Inc. | Mechanical syringe accessory |
AU2014290513B2 (en) | 2013-07-18 | 2017-07-27 | The General Hospital Corporation | Vessel treatment systems, methods, and kits |
ITMO20130228A1 (it) | 2013-08-02 | 2015-02-03 | Biomed Device Srl | Sistema e metodo per aliquotare grasso da liposuzione ai fini dell'uso e della crioconservazione |
US9248384B2 (en) | 2013-10-02 | 2016-02-02 | Allergan, Inc. | Fat processing system |
CN103598901A (zh) * | 2013-10-24 | 2014-02-26 | 苏雪莲 | 一种脂肪移植装置 |
US20150314284A1 (en) * | 2014-05-02 | 2015-11-05 | Francesca Dagny TEKULA | Specimen container for biological materials |
EP3137139A1 (en) | 2014-05-02 | 2017-03-08 | Lifecell Corporation | Injection sensor with feedback mechanism |
US20170188572A1 (en) | 2014-05-02 | 2017-07-06 | Francesca Dagny TEKULA | Specimen container for biological materials |
US10029048B2 (en) | 2014-05-13 | 2018-07-24 | Allergan, Inc. | High force injection devices |
US10279325B1 (en) * | 2014-09-04 | 2019-05-07 | Black Tie Medical, Inc. | System and method for harvesting emulsified fat and stem cells |
AU2015327812B2 (en) | 2014-10-03 | 2021-04-15 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of muscular dystrophy |
AU2016219956B2 (en) | 2015-02-19 | 2020-08-13 | Lifecell Corporation | Tissue processing device and associated systems and methods |
CA2976544A1 (en) | 2015-03-10 | 2016-09-15 | Allergan Pharmaceuticals Holdings (Ireland) Unlimited Company | Multiple needle injector |
US10130740B2 (en) * | 2015-03-17 | 2018-11-20 | Wells Johnson Company | Pressure control during processing of adipose tissue |
WO2016183135A1 (en) | 2015-05-12 | 2016-11-17 | Parker Isaac Instruments, Llc | Pathologic staging compression apparatus and methods |
US9861939B2 (en) | 2015-10-02 | 2018-01-09 | Lawrence Livermore National Security, Llc | Filtration device for rapid separation of biological particles from complex matrices |
BR112018008059A2 (pt) | 2015-10-21 | 2018-10-23 | Lifecell Corp | sistemas e métodos para controle de dispositivo médico |
ES2775597T3 (es) | 2015-10-21 | 2020-07-27 | Lifecell Corp | Sistemas y métodos para la gestión de tubos |
WO2017112755A1 (en) | 2015-12-22 | 2017-06-29 | Lifecell Corporation | Syringe filling device for fat transfer |
US11253551B2 (en) | 2016-01-11 | 2022-02-22 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and exosomes secreted by such cells in the treatment of heart failure with preserved ejection fraction |
KR102232054B1 (ko) | 2016-04-08 | 2021-03-26 | 알레간 인코포레이티드 | 흡인 및 주입 디바이스 |
EP3239286A1 (en) | 2016-04-26 | 2017-11-01 | Ludwig Boltzmann Gesellschaft | Non-enzymatic method and milling device |
WO2017189918A1 (en) * | 2016-04-27 | 2017-11-02 | Hagarty Sarah Elizabeth | A closed loop system for direct harvest and transfer for high volume fat grafting |
US20170312403A1 (en) | 2016-04-27 | 2017-11-02 | Sarah Elizabeth Hagarty | Simple Closed Loop System for Direct Harvest and Transfer for High Volume Fat Grafting |
US11351200B2 (en) | 2016-06-03 | 2022-06-07 | Cedars-Sinai Medical Center | CDC-derived exosomes for treatment of ventricular tachyarrythmias |
BR112019003871A2 (pt) | 2016-08-30 | 2019-07-16 | Lifecell Corp | sistemas e métodos para controle de dispositivo médico |
WO2018057542A1 (en) | 2016-09-20 | 2018-03-29 | Cedars-Sinai Medical Center | Cardiosphere-derived cells and their extracellular vesicles to retard or reverse aging and age-related disorders |
WO2018111550A1 (en) * | 2016-12-12 | 2018-06-21 | Werd, Llc | A syringe for processing fat grafts and related methods |
JP7336769B2 (ja) | 2017-04-19 | 2023-09-01 | シーダーズ―シナイ メディカル センター | 骨格筋ジストロフィーを治療する方法及び組成物 |
WO2018204929A1 (en) * | 2017-05-05 | 2018-11-08 | Hagarty Sarah Elizabeth | A system for the harvest and transfer for high volume fat grafting using a centrifugal pump |
CN107174678B (zh) * | 2017-06-30 | 2023-07-18 | 杨忠 | 一种自体脂肪采集、净化及移植装置 |
CN107641595B (zh) * | 2017-08-15 | 2023-03-21 | 中国人民解放军第二军医大学第二附属医院 | 关节镜下获取无菌膝髌下脂肪垫组织提取装置及方法 |
CA3073811A1 (en) | 2017-08-28 | 2019-03-07 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Methods and devices for use in treatment of plantar fasciitis and fat grafting |
US20190185814A1 (en) * | 2017-12-14 | 2019-06-20 | Lifecell Corporation | Device and methods for tissue processing |
WO2019126068A1 (en) | 2017-12-20 | 2019-06-27 | Cedars-Sinai Medical Center | Engineered extracellular vesicles for enhanced tissue delivery |
CN109876201A (zh) * | 2019-03-07 | 2019-06-14 | 杭州百桥医疗技术有限公司 | 一种自体脂肪抽吸、纯化、精准注射与安全监测系统 |
CN109925014B (zh) * | 2019-04-03 | 2024-03-22 | 北京阿拉布丁生物科技有限公司 | 一种脂肪提纯装置 |
KR102075422B1 (ko) * | 2019-04-05 | 2020-02-11 | 주식회사 이뮤니스바이오 | 세포 회수용 튜브 및 이를 포함하는 주사 키트 |
CN114364784B (zh) * | 2019-09-30 | 2024-02-02 | 泰尔茂株式会社 | 试样的粉碎方法 |
KR102091151B1 (ko) * | 2019-10-08 | 2020-03-20 | 주식회사 로킷헬스케어 | 당뇨병성 족부병증 환자 맞춤형 피부 재생 시트의 제조방법 및 이를 이용하여 제조된 당뇨병성 족부병증 환자 맞춤형 피부 재생 시트 |
IT201900022350A1 (it) * | 2019-12-04 | 2021-06-04 | Hydra S R L | Dispositivo di frammentazione di tessuti in ambiente chiuso sterile con procedura asettica e suo metodo |
US20210332315A1 (en) * | 2020-04-22 | 2021-10-28 | Ben M. Khalaj | Filtration-centrifuge tube apparatus for harvesting adipose derived stem cells |
CN113116414A (zh) * | 2021-04-22 | 2021-07-16 | 任学会 | 一种自体脂肪填充移植使用的全封闭系统 |
US11679198B2 (en) | 2021-04-28 | 2023-06-20 | Chopra Gryskiewicz, LLC | System and related methods for fat harvesting |
KR102593281B1 (ko) * | 2021-07-05 | 2023-10-24 | 주식회사 바이오솔루션 | 스페로이드형 세포치료제 이식용 주입장치 |
CN113583950A (zh) * | 2021-08-06 | 2021-11-02 | 合肥滴碧云生物科技有限公司 | 一种制备干细胞活性因子的方法及其应用 |
FR3131217B1 (fr) * | 2021-12-23 | 2023-12-22 | Groupe Sebbin | Dispositif de collecte de tissu à réservoir de taille modulable |
US20240182837A1 (en) * | 2022-12-01 | 2024-06-06 | Sientra, Inc. | Lipoaspirate wash system and method |
JP7562090B1 (ja) | 2023-10-19 | 2024-10-07 | 国立大学法人高知大学 | マーカー、マーカー留置具及びマーカー検出装置 |
Family Cites Families (103)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5212071A (en) | 1988-04-01 | 1993-05-18 | The Johns Hopkins University | Nucleic acids encoding a human C3b/C4b receptor (CR1) |
US5981481A (en) | 1974-12-06 | 1999-11-09 | The Johns Hopkins University | Human C3b/C4b receptor (CR1) |
IL89790A (en) | 1988-04-01 | 2002-05-23 | Johns Hopking University | Sequences of nucleic acids encoding and cells producing CR1 protein and methods for its production and purification |
US5256642A (en) | 1988-04-01 | 1993-10-26 | The Johns Hopkins University | Compositions of soluble complement receptor 1 (CR1) and a thrombolytic agent, and the methods of use thereof |
DK0427247T3 (da) | 1989-11-09 | 1998-09-28 | Asta Medica Ag | Lægemiddel indeholdende R-alpha- lipoinsyre eller S-alphalipoinsyre som aktiv bestanddel |
US5052999A (en) | 1990-01-29 | 1991-10-01 | Klein Jeffrey A | Liposuction method and apparatus |
AU662146B2 (en) | 1991-03-19 | 1995-08-24 | Cytrx Corporation | Polyoxypropylene/polyoxyethylene copolymers with improved biological activity |
US5470568A (en) | 1992-02-13 | 1995-11-28 | Arch Development Corporation | Methods and compositions of a polymer (poloxamer) for cell repair |
US5605687A (en) | 1992-05-15 | 1997-02-25 | Arch Development Corporation | Methods and compositions of a polymer (poloxamer) for repair of electrical injury |
US5569670A (en) | 1992-06-05 | 1996-10-29 | Asta Medica Aktiengesellschaft | Combination medications containing alpha-lipoic acid and related |
DE4229914A1 (de) | 1992-09-08 | 1994-03-10 | Basf Ag | Verbessertes Verfahren zur Herstellung von R/S-Ï-Liponsäure oder R/S-â-Liponsäure |
WO1995001332A1 (fr) | 1993-07-01 | 1995-01-12 | Nkk Corporation | Derive d'arylsulfonamide et composition pharmaceutique le contenant |
DE4343593C2 (de) | 1993-12-21 | 1998-05-20 | Asta Medica Ag | Verwendung von R-(+)-alpha-Liponsäure, R-(-)-Dihydroliponsäure oder der Metabolite sowie deren Salze, Ester, Amide zur Behandlung kompensierter und dekompensierter Insulinresistenz |
DE4427079C2 (de) | 1994-07-30 | 2002-12-19 | Viatris Gmbh | Verfahren zur Racemisierung von Enantiomeren der alpha-Liponsäure |
US5716404A (en) | 1994-12-16 | 1998-02-10 | Massachusetts Institute Of Technology | Breast tissue engineering |
US5681561A (en) | 1995-06-07 | 1997-10-28 | Life Medical Sciences, Inc. | Compositions and methods for improving autologous fat grafting |
US5709868A (en) | 1995-09-20 | 1998-01-20 | Perricone; Nicholas V. | Lipoic acid in topical compositions |
US6752999B2 (en) | 1995-09-20 | 2004-06-22 | Nicholas V. Perricone | Method of skin care and/or treatment using lipoic acid |
US6328712B1 (en) | 1996-02-28 | 2001-12-11 | Smisson-Cartledge Biomedical Corporation | Rapid infusion system |
US5879876A (en) | 1997-03-24 | 1999-03-09 | Lifenet | Continuous-multi-step dilution process and apparatus, for the removal of cryoprotectants from cryopreserved tissues |
US7220557B2 (en) | 1997-04-24 | 2007-05-22 | Human Genome Sciences, Inc. | METH1 polynucleotides |
US5965618A (en) | 1997-11-17 | 1999-10-12 | Perricone; Nicholas V. | Treatment of scar tissue using lipoic acid |
US6365623B1 (en) | 1997-11-17 | 2002-04-02 | Nicholas V. Perricone | Treatment of acne using lipoic acid |
US6090842A (en) | 1998-03-10 | 2000-07-18 | The Regents Of The University Of California | Lipoic acid analogs |
US6858617B2 (en) | 1998-05-26 | 2005-02-22 | Smithkline Beecham Corporation | Substituted imidazole compounds |
WO1999061440A1 (en) | 1998-05-26 | 1999-12-02 | Smithkline Beecham Corporation | Novel substituted imidazole compounds |
BR9914789A (pt) | 1998-10-26 | 2001-10-02 | Univ New York State Res Found | Derivados de ácido lipóico e seus usos no tratamento de doença |
EP1224322A2 (en) | 1999-02-22 | 2002-07-24 | Variagenics, Inc. | Gene sequence variations with utility in determining the treatment of disease |
US6204288B1 (en) | 1999-03-08 | 2001-03-20 | The University Of Mississippi | 1,2-dithiolane derivatives |
AR042572A1 (es) | 1999-04-02 | 2005-06-29 | Sod Conseils Rech Applic | Derivados de acido lipoico, procedimiento para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y utilizacion de dichos derivados para la preparacion de los referidos medicamentos |
US6103255A (en) | 1999-04-16 | 2000-08-15 | Rutgers, The State University | Porous polymer scaffolds for tissue engineering |
AU5045900A (en) | 1999-05-25 | 2000-12-12 | Beth Israel Deaconess Medical Center | Meth1 and meth2 polynucleotides and polypeptides |
US6316247B1 (en) * | 1999-06-15 | 2001-11-13 | University Of Pittsburgh | System and method for refining liposuctioned adipose tissue |
CA2387685A1 (en) | 1999-10-27 | 2001-05-03 | Human Genome Sciences, Inc. | Stanniocalcin proteins and nucleic acids and methods based thereon |
US6673033B1 (en) * | 1999-11-24 | 2004-01-06 | Medrad, Inc. | Injectors, injector systems and injector control |
WO2001093824A1 (en) | 2000-06-06 | 2001-12-13 | Basf Aktiengesellschaft | Use of an (r)-enantiomer of lipoic acid in cosmetics and dermatologicals |
WO2002016557A2 (en) | 2000-08-21 | 2002-02-28 | Rice University | Tissue engineering scaffolds promoting matrix protein production |
US6277842B1 (en) | 2000-10-17 | 2001-08-21 | James Alexander Carthron | Dietary supplemental method for fat and weight reduction |
US7227007B2 (en) | 2000-12-28 | 2007-06-05 | Asahi Kasei Pharma Corporation | NF-κB activating gene |
CA2440058A1 (en) | 2001-03-07 | 2002-09-19 | Bristol-Myers Squibb Company | Polynucleotide encoding a novel human g-protein coupled receptor, hgprbmy27 |
EP1377597A4 (en) | 2001-03-22 | 2005-02-09 | Bristol Myers Squibb Co | POLYNUCLEOTIDE CODING FOR A NEW MEMBER OF THE IMMUNOGLOBULIN SUPERFAMILY, APEX4, AND ITS VARIATIONS AND SPICE VARIANTS |
WO2002076288A2 (en) | 2001-03-27 | 2002-10-03 | Board Of Regents The University Of Texas System | Biodegradable, electrically conductiong polymer for tissue engineering applications |
US20040086896A1 (en) | 2001-04-19 | 2004-05-06 | Julie Carman | Polynucleotides and polypeptides associated with the NF-kB pathway |
US20030224486A1 (en) | 2001-04-19 | 2003-12-04 | Julie Carman | Polynucleotides and polypeptides associated with the NF-kB pathway |
JP2004527573A (ja) | 2001-04-24 | 2004-09-09 | パーデュー・リサーチ・ファウンデーション | 哺乳類の神経組織損傷の治療のための方法及び組成物 |
US20030103913A1 (en) | 2001-05-07 | 2003-06-05 | Nathoo Salim A. | Metal activated tooth whitening compositions |
US7504481B2 (en) | 2001-08-02 | 2009-03-17 | Bristol-Meyers Squibb Company | TRP channel family member, LTRPC3 polypeptides |
AU2002326497A1 (en) | 2001-08-02 | 2003-02-17 | Bristol-Myers Squibb Company | Polynucleotide encoding a novel trp channel family member, ltrpc3, and splice variants thereof |
US20040116350A1 (en) | 2001-09-17 | 2004-06-17 | Paul Wentworth Jr | Methods and compositions relating to hydrogen peroxide and superoxide production by antibodies |
US7452532B2 (en) * | 2001-09-30 | 2008-11-18 | Scicotec Gmbh | Transluminal application of adult stem cells for body organ tissue repair |
AU2002357135C1 (en) | 2001-12-07 | 2009-01-22 | Macropore Biosurgery, Inc. | Systems and methods for treating patients with processed lipoaspirate cells |
US7514075B2 (en) * | 2001-12-07 | 2009-04-07 | Cytori Therapeutics, Inc. | Systems and methods for separating and concentrating adipose derived stem cells from tissue |
US7651684B2 (en) * | 2001-12-07 | 2010-01-26 | Cytori Therapeutics, Inc. | Methods of using adipose tissue-derived cells in augmenting autologous fat transfer |
AU2003226131A1 (en) | 2002-03-28 | 2003-10-13 | Bristol-Myers Squibb Company | Novel human cell surface protein with immunoglobulin folds, bgs-19 |
AU2003222109A1 (en) | 2002-03-29 | 2003-10-13 | Bristol-Myers Squibb Company | Polynucleotides encoding novel two splice variants of a human cell surface protein with immunologobulin folds, bgs5g and bgs5i |
US20040087543A1 (en) | 2002-04-25 | 2004-05-06 | Zachary Shriver | Methods and products for mucosal delivery |
AU2003299496A1 (en) | 2002-05-14 | 2004-05-25 | Bristol-Myers Squibb Company | Polynucleotide encoding novel human g-protein coupled receptors, and splice variants thereof |
WO2003106663A1 (ja) | 2002-06-18 | 2003-12-24 | エーザイ株式会社 | 遺伝子治療用初代培養脂肪細胞 |
US20040204576A1 (en) | 2002-07-02 | 2004-10-14 | Donald Jackson | Polynucleotides encoding a novel human phosphatase, BMY_HPP13 |
US7550155B2 (en) | 2002-07-29 | 2009-06-23 | Transform Pharmaceuticals Inc. | Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses |
EP1539282A2 (en) * | 2002-08-06 | 2005-06-15 | GenVec, Inc. | Improved injection system |
US20040101959A1 (en) | 2002-11-21 | 2004-05-27 | Olga Marko | Treatment of tissue with undifferentiated mesenchymal cells |
AU2003295824A1 (en) | 2002-11-22 | 2004-06-18 | Incyte Corporation | Cell adhesion and extracellular matrix proteins |
KR100473568B1 (ko) | 2003-01-25 | 2005-03-10 | 이희영 | 밀폐형 지방이식 시스템 |
US20060184101A1 (en) * | 2003-04-21 | 2006-08-17 | Ravi Srinivasan | Microjet devices and methods for drug delivery |
CN1842589B (zh) | 2003-06-25 | 2012-04-25 | 马克罗珀尔生物外科公司 | 用于从组织分离并且浓缩再生细胞的系统和方法 |
US20040265345A1 (en) | 2003-06-30 | 2004-12-30 | Perricone Nicholas V. | Treatment of skin damage using acetyl carnitine and lipoic acid |
FR2856891B1 (fr) | 2003-07-04 | 2007-09-07 | Stem Alpha | Milieu de conservation d'organes, de tissus biologiques ou de cellules vivantes |
US20050118632A1 (en) | 2003-11-06 | 2005-06-02 | Jian Chen | Polynucleotides and polypeptides encoding a novel metalloprotease, Protease-40b |
WO2005046438A2 (en) | 2003-11-06 | 2005-05-26 | Pluromed, Inc. | Internal clamp for surgical procedures |
US20050208095A1 (en) | 2003-11-20 | 2005-09-22 | Angiotech International Ag | Polymer compositions and methods for their use |
US20050124073A1 (en) * | 2003-12-09 | 2005-06-09 | Entire Interest | Fat collection and preparation system and method |
US7087369B2 (en) | 2003-12-17 | 2006-08-08 | The Regents Of The University Of California | Cornea preservation medium |
EP1702058B1 (en) | 2004-01-08 | 2012-06-13 | North Carolina State University | Methods and devices for microencapsulation of cells |
US7588732B2 (en) | 2004-03-30 | 2009-09-15 | Genesis Biosystems, Inc. | Autologus tissue harvesting and irrigation device |
WO2005099758A2 (en) | 2004-04-17 | 2005-10-27 | The Board Of Trustees The Leland Standford Junior University | Injectable bioartificial tissue matrix |
GB0414825D0 (en) | 2004-07-02 | 2004-08-04 | Biostatus Ltd | Gel formulations and uses thereof |
EP1804813A4 (en) | 2004-09-27 | 2011-09-07 | Vical Inc | FORMULATIONS AND METHOD FOR THE TREATMENT OF INFLAMMATORY DISEASES |
WO2006044738A2 (en) | 2004-10-18 | 2006-04-27 | Maroon Biotech Corporation | Methods and compositions for treatment of free radical injury |
US20060127384A1 (en) | 2004-12-09 | 2006-06-15 | Sergio Capaccioli | Coenzyme Q10 as antiapoptotic agent |
US7789872B2 (en) * | 2005-03-23 | 2010-09-07 | Shippert Ronald D | Tissue transplantation method and apparatus |
US7794449B2 (en) * | 2005-03-23 | 2010-09-14 | Shippert Ronald D | Tissue transplantation method and apparatus |
CN105394748A (zh) | 2005-04-06 | 2016-03-16 | 雀巢产品技术援助有限公司 | 从营养方面改善葡萄糖控制和胰岛素作用的方法和组合物 |
WO2007005668A2 (en) | 2005-06-30 | 2007-01-11 | Amgen Inc. | Bis-aryl kinase inhibitors and their use in the treatment of inflammation, angiogenesis and cancer |
WO2007009285A1 (en) | 2005-07-21 | 2007-01-25 | Eth Zurich | Cryo-conservation medium for in-vitro cultured cells |
US9265792B2 (en) | 2005-11-16 | 2016-02-23 | Patricia A. Riley | Integument cell regeneration formulation |
EP1965811A4 (en) * | 2005-11-21 | 2011-01-19 | Nicast Ltd | DEVICE AND METHOD FOR CELL GRAFT |
EP1988159B1 (en) | 2006-01-13 | 2014-03-05 | Two Cells Co., Ltd. | Additive for culture medium for use in serum-free culture of animal cell, kit, and use of the additive or kit |
KR100764640B1 (ko) * | 2006-03-08 | 2007-10-10 | 세원셀론텍(주) | 지방조직 수복용 키트 |
KR100683280B1 (ko) * | 2006-07-11 | 2007-02-16 | 메디칸(주) | 지방 흡입 및 이식용 주사기 |
US7960098B2 (en) | 2007-07-12 | 2011-06-14 | Warsaw Orthoperic, Inc. | Methods and compositions for the preservation of cells and tissues |
US7892724B2 (en) | 2007-07-12 | 2011-02-22 | Warsaw Orthopedic, Inc | Method for enhancing the viability of mammalian cells, tissues and organs using a solution comprising two low molecular weight PEGs |
WO2009055610A1 (en) * | 2007-10-26 | 2009-04-30 | Cytori Therapeutics, Inc. | Syringe system for controlled delivery or removal of material |
BRPI0908087A2 (pt) | 2008-02-11 | 2015-08-25 | Univ Johns Hopkins | Composições e métodos para implante de tecido adipose e produtos de tecido adiposo |
JP2010063441A (ja) | 2008-09-12 | 2010-03-25 | Olympus Corp | 脂肪除去方法と生体組織処理方法 |
JP5795961B2 (ja) | 2008-10-21 | 2015-10-14 | ザ ジェネラル ホスピタル コーポレイション | 細胞移植 |
DE102009022346B4 (de) | 2009-05-15 | 2011-05-19 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Automatisches Abtrennen von Fettgewebe |
US8790519B2 (en) * | 2009-06-16 | 2014-07-29 | Biomet Biologics, Llc | Liquid separation from adipose tissue |
CA2768613A1 (en) | 2009-07-20 | 2011-01-27 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Methods and compositions for improving the viability of cryopreserved cells |
CN201492455U (zh) * | 2009-09-25 | 2010-06-02 | 金哲 | 用于脂肪抽取、分离和移植的装置 |
WO2011059733A2 (en) | 2009-10-29 | 2011-05-19 | The General Hospital Corporation D/B/A Massachusetts General Hospital | Use of lipoic acid in cell transplantation |
BR112012029465A2 (pt) | 2010-05-21 | 2017-03-01 | Sound Surgical Tech Llc | dispositivo ultrassônico para retirada de tecido adiposo |
US10184110B2 (en) | 2010-08-06 | 2019-01-22 | The General Hospital Corporation | System and apparatus for cell treatment |
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WO2012019103A2 (en) | 2012-02-09 |
JP2013538081A (ja) | 2013-10-10 |
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EP2601299A4 (en) | 2014-03-19 |
US10184110B2 (en) | 2019-01-22 |
JP6072684B2 (ja) | 2017-02-01 |
CN103153376B (zh) | 2018-04-20 |
EP3530741A1 (en) | 2019-08-28 |
WO2012019103A8 (en) | 2012-12-27 |
BR112013002859B1 (pt) | 2020-10-06 |
CN108504539B (zh) | 2021-11-02 |
EP2601299A2 (en) | 2013-06-12 |
EP2601299B1 (en) | 2019-04-24 |
CN103153376A (zh) | 2013-06-12 |
KR20140023247A (ko) | 2014-02-26 |
EP3530741B1 (en) | 2021-04-07 |
CN108504539A (zh) | 2018-09-07 |
US20130158515A1 (en) | 2013-06-20 |
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