MX370137B - Sistema para purificar ciertas poblaciones celulares en sangre o medula osea por agotamiento. - Google Patents

Sistema para purificar ciertas poblaciones celulares en sangre o medula osea por agotamiento.

Info

Publication number
MX370137B
MX370137B MX2016008900A MX2016008900A MX370137B MX 370137 B MX370137 B MX 370137B MX 2016008900 A MX2016008900 A MX 2016008900A MX 2016008900 A MX2016008900 A MX 2016008900A MX 370137 B MX370137 B MX 370137B
Authority
MX
Mexico
Prior art keywords
blood
bone marrow
cell populations
depleting
certain cell
Prior art date
Application number
MX2016008900A
Other languages
English (en)
Inventor
Philip H Coelho
Original Assignee
Thermogenesis Corp Star
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44649609&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX370137(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thermogenesis Corp Star filed Critical Thermogenesis Corp Star
Publication of MX370137B publication Critical patent/MX370137B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/10—Apparatus for enzymology or microbiology rotatably mounted
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38—Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/16—Apparatus for enzymology or microbiology containing, or adapted to contain, solid media
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34—Purifying; Cleaning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/08—Lipoids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/10—Bone-marrow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B13/00—Control arrangements specially designed for centrifuges; Programme control of centrifuges
    • B04B2013/006—Interface detection or monitoring of separated components

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • External Artificial Organs (AREA)
  • Centrifugal Separators (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

La presente invención se refiere a un aparato y un método para purificar y cosechar ciertas poblaciones celulares en la sangre o en la médula ósea al agotar al menos uno de los glóbulos rojos, granulocitos y plaquetas desde una muestra que incluye sangre, médula ósea, o células de fracción vascular estromal separadas del tejido adiposo. El aparato se compone de un cartucho auto-sustentable, rígido, desechable y estéril dentro del que ocurre un agotamiento, purificación y cosecha automáticos de poblaciones celulares objetivo, y todos los componentes pueden ser distribuidos.
MX2016008900A 2010-03-18 2011-03-17 Sistema para purificar ciertas poblaciones celulares en sangre o medula osea por agotamiento. MX370137B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31510910P 2010-03-18 2010-03-18
US201161436964P 2011-01-27 2011-01-27
PCT/US2011/028863 WO2011116221A1 (en) 2010-03-18 2011-03-17 System for purifying certain cell populations in blood or bone marrow by depleting others

Publications (1)

Publication Number Publication Date
MX370137B true MX370137B (es) 2019-11-29

Family

ID=44649609

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012010744A MX341634B (es) 2010-03-18 2011-03-17 Sistema para purificar ciertas poblaciones celulares en sangre o medula osea por agotamiento.
MX2016008900A MX370137B (es) 2010-03-18 2011-03-17 Sistema para purificar ciertas poblaciones celulares en sangre o medula osea por agotamiento.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
MX2012010744A MX341634B (es) 2010-03-18 2011-03-17 Sistema para purificar ciertas poblaciones celulares en sangre o medula osea por agotamiento.

Country Status (12)

Country Link
US (4) US8747289B2 (es)
EP (1) EP2547346B1 (es)
JP (2) JP5635177B2 (es)
KR (1) KR101946441B1 (es)
CN (1) CN102946890B (es)
AU (1) AU2011227203B2 (es)
CA (1) CA2793648C (es)
MX (2) MX341634B (es)
MY (1) MY160835A (es)
RU (1) RU2596795C2 (es)
SG (1) SG183963A1 (es)
WO (1) WO2011116221A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013111130A1 (en) 2012-01-23 2013-08-01 Estar Technologies Ltd A system and method for obtaining a cellular sample enriched with defined cells such as platelet rich plasma(prp)
WO2014110180A1 (en) * 2013-01-12 2014-07-17 Cesca Therapeutics, Inc. Rapid infusion of autologous bone marrow derived stem cells
JP6175841B2 (ja) * 2013-03-26 2017-08-09 株式会社ジェイ・エム・エス 血液成分移送用ポート及びこれを備える血液成分分離容器
JP6154904B2 (ja) * 2013-08-22 2017-06-28 株式会社ジェイ・エム・エス 血液成分分離用装置
EP3043643B1 (en) * 2013-09-10 2019-04-24 Thermogenesis Corp. Method and apparatus for cryopreservation of blood cells in a sterile environment
CA2939595A1 (en) * 2014-02-25 2015-09-03 Theranos, Inc. Systems, devices, and methods for sample integrity verification
WO2015172255A1 (en) 2014-05-16 2015-11-19 Qvella Corporation Apparatus, system and method for performing automated centrifugal separation
PT3757206T (pt) 2014-11-05 2024-05-21 Juno Therapeutics Inc Métodos de transdução e processamento de células
US11291931B2 (en) 2014-12-15 2022-04-05 Akadeum Life Sciences, Inc. Method and system for buoyant separation
US9926524B2 (en) 2014-12-22 2018-03-27 Saint-Gobain Performance Plastics Corporation Gas permeable material
US10280390B2 (en) 2014-12-22 2019-05-07 Saint-Gobain Performance Plastics Corporation System for culture of cells in a controlled environment
US10655097B2 (en) 2014-12-22 2020-05-19 Saint-Gobain Performance Plastics Corporation T-cell culture double bag assembly
WO2017023542A1 (en) 2015-07-31 2017-02-09 DePuy Synthes Products, Inc. Method of preparing an osteogenic bone graft
EP3397306B1 (en) 2015-12-29 2021-06-02 Thermogenesis Corp. Cell separation devices, systems, and methods
CN106267426A (zh) * 2016-08-15 2017-01-04 董稳 一种离心分离法血浆采集装置
CN109982731B (zh) * 2016-10-03 2022-08-19 泰尔茂比司特公司 离心流体分离设备
EP3717127A1 (en) * 2017-11-30 2020-10-07 Corning Incorporated Pipette with encapsulated or integral filter, and method and apparatus for forming same
EP3501660A1 (de) * 2017-12-19 2019-06-26 Antonio Pinto Verfahren und vorrichtung zur stofftrennung durch zentrifugation
CN111886076B (zh) * 2018-01-22 2022-09-23 西诺吉产品私人有限公司 用于悬浮在流体中的浓缩颗粒回收的系统、方法和控制器
CN108359592B (zh) * 2018-03-05 2021-05-28 东营凤起生物科技发展有限公司 一种医用造血干细胞采集仪
WO2019178314A1 (en) * 2018-03-14 2019-09-19 Thermogenesis Corporation Buoyancy-activated cell sorting (bacs)-compatible activation/transduction systems and methods
CN112437692B (zh) 2018-07-09 2022-06-24 爱卡德姆生命科学公司 用于有浮力颗粒处理的系统和方法
US11866042B2 (en) 2018-08-20 2024-01-09 Indian Motorcycle International, LLC Wheeled vehicle adaptive speed control method and system
FR3091924B1 (fr) * 2019-01-23 2021-10-15 Erba Diagnostics Ltd Procédé d’optimisation de la concentration en éléments d’intérêt à des fins de mesures visuelles sur un échantillon biologique
US11738288B2 (en) 2020-06-29 2023-08-29 Jacques Chammas Automated system and method to isolate specific cells from blood or bone marrow
CN111996117B (zh) * 2020-09-08 2022-12-16 天晴干细胞股份有限公司 集运输、采集于一体的胎盘血提取装置及方法
KR102552182B1 (ko) * 2021-08-10 2023-07-07 (주)웰포트 원심분리장치 및 이를 이용한 혈소판 풍부 혈장 추출방법
WO2023028329A1 (en) 2021-08-26 2023-03-02 Akadeum Life Sciences, Inc. Method and system for buoyant separation

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4111355A (en) * 1977-06-15 1978-09-05 Beckman Instruments, Inc. Multi-compartment centrifuge rotor liner
US4751001A (en) * 1984-09-24 1988-06-14 Becton Dickinson And Company Blood partitioning apparatus
US4919537A (en) * 1987-10-29 1990-04-24 Beckman Instruments Inc. UV scanning system for centrifuge
US5520885A (en) 1993-01-19 1996-05-28 Thermogenesis Corporation Fibrinogen processing apparatus, method and container
US5646004A (en) * 1994-08-31 1997-07-08 Activated Cell Therapy, Inc. Methods for enriching fetal cells from maternal body fluids
US5704889A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus
US5674173A (en) * 1995-04-18 1997-10-07 Cobe Laboratories, Inc. Apparatus for separating particles
EP0868215B1 (en) * 1995-12-01 2002-01-30 Baker Hughes Incorporated Method and apparatus for controlling and monitoring continuous feed centrifuge
SE9600713L (sv) * 1996-02-26 1997-10-17 Omega Medicinteknik Ab Metod för separering av celler, speciellt blodplättar och pås-set därför
US5866071A (en) * 1996-03-06 1999-02-02 National Science Council Centrifuge tube with a built-in small tubing for separation following density gradients centrifugation
US6334842B1 (en) * 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
US6652475B1 (en) 1999-07-07 2003-11-25 Mission Medical, Inc. Automated blood component separation system
CN2393550Y (zh) * 1999-09-09 2000-08-30 浙江博朗生物工程有限公司 血液自动分离机
US7241281B2 (en) 2002-04-08 2007-07-10 Thermogenesis Corporation Blood component separation method and apparatus
US7211191B2 (en) * 2004-09-30 2007-05-01 Thermogenesis Corp. Blood component separation method and apparatus
US7374678B2 (en) 2002-05-24 2008-05-20 Biomet Biologics, Inc. Apparatus and method for separating and concentrating fluids containing multiple components
CN1261183C (zh) * 2004-06-11 2006-06-28 西安瑞捷生物医疗技术有限公司 一种制备血小板富集血浆的装置及制备方法
CN2721094Y (zh) 2004-07-21 2005-08-31 张长青 一种用于制作富血小板血浆的离心管
CN100467075C (zh) * 2005-08-09 2009-03-11 郭经纬 一种多向离心式连续性血液成分分离设备
GB0608451D0 (en) * 2006-04-28 2006-06-07 Ge Healthcare Bio Sciences Ab Centrifugal separation system
US8273310B2 (en) * 2006-09-05 2012-09-25 Samsung Electronics Co., Ltd. Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device
KR100818290B1 (ko) * 2006-12-11 2008-03-31 삼성전자주식회사 성분 분리 장치 및 성분 분리 방법
EP2126044A4 (en) * 2007-03-28 2010-04-07 Thermogenesis Corp COMPOSITIONS OF STEM CELLS AND RECOVERED PROGENITOR CELLS FROM BONE MOLEL OR UMBILICAL BLOOD, SYSTEM AND METHOD FOR THEIR PREPARATION
CN201182744Y (zh) * 2008-04-15 2009-01-21 四川南格尔生物医学股份有限公司 血液成分分离和收集一体化的离心袋
WO2010005557A2 (en) * 2008-07-07 2010-01-14 Arteriocyte Medical Systems, Inc. Biological therapeutic compositions and methods thereof
US8177072B2 (en) 2008-12-04 2012-05-15 Thermogenesis Corp. Apparatus and method for separating and isolating components of a biological fluid
AU2010242824A1 (en) * 2009-05-01 2011-12-15 Fraunhofer, Usa, Inc. Disposal separator/concentrator device and method of use

Also Published As

Publication number Publication date
RU2012144390A (ru) 2014-04-27
US20140212912A1 (en) 2014-07-31
US20170199106A1 (en) 2017-07-13
WO2011116221A1 (en) 2011-09-22
AU2011227203A1 (en) 2012-10-11
MY160835A (en) 2017-03-31
EP2547346A4 (en) 2018-03-28
EP2547346A1 (en) 2013-01-23
US20140212914A1 (en) 2014-07-31
AU2011227203B2 (en) 2017-01-05
JP5635177B2 (ja) 2014-12-03
JP6016867B2 (ja) 2016-10-26
MX2012010744A (es) 2013-03-18
CA2793648A1 (en) 2011-09-22
KR20130056224A (ko) 2013-05-29
KR101946441B1 (ko) 2019-04-22
CA2793648C (en) 2017-06-06
CN102946890B (zh) 2017-03-08
EP2547346B1 (en) 2020-11-04
US8747289B2 (en) 2014-06-10
US20130029370A1 (en) 2013-01-31
US9599545B2 (en) 2017-03-21
RU2596795C2 (ru) 2016-09-10
JP2013526901A (ja) 2013-06-27
JP2015037590A (ja) 2015-02-26
SG183963A1 (en) 2012-10-30
CN102946890A (zh) 2013-02-27
MX341634B (es) 2016-08-08

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