BR112012024910A2 - composição contendo vesícula e método para sua produção - Google Patents
composição contendo vesícula e método para sua produçãoInfo
- Publication number
- BR112012024910A2 BR112012024910A2 BR112012024910A BR112012024910A BR112012024910A2 BR 112012024910 A2 BR112012024910 A2 BR 112012024910A2 BR 112012024910 A BR112012024910 A BR 112012024910A BR 112012024910 A BR112012024910 A BR 112012024910A BR 112012024910 A2 BR112012024910 A2 BR 112012024910A2
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- vesicle
- present
- water
- gallbladder
- Prior art date
Links
- 210000000232 gallbladder Anatomy 0.000 title abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 2
- 239000003945 anionic surfactant Substances 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 229920001296 polysiloxane Polymers 0.000 abstract 2
- 229920002545 silicone oil Polymers 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000003012 bilayer membrane Substances 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- -1 polyoxyethylene Polymers 0.000 abstract 1
- 229940104261 taurate Drugs 0.000 abstract 1
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/14—Liposomes; Vesicles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/466—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfonic acid derivatives; Salts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Emergency Medicine (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
composição contendo vesícula e método para sua produção. a presente invenção refere-se a uma composição contendo vesículas tendo uma excelente estabilidade na presença de agente medicinal solúvel em água. uma composição contendo vesícula da presente invenção é caracterizada por compreender: (a) um tensoativo à base de silicone, (b) um ou mais tensoativos aniônicos selecionados de éter fosfato de polioxietileno alquila (12 a 15), taurato de acil metila e glutamato de acila, em uma quantidade de 0,001 a 0,2 % em massa, (c) um óleo polar tendo iob de 0,05 a 0,80 e/ou óleo de silicone, e (d) água contendo um agente medicinal solúvel em água em uma quantidade de 0,5 a 5% em massa com base na composição, em que (a) tensoativo com base em silicone forma vesículas; (b) os tensoativos aniônicos se ligam a uma superfície das vesículas; e (c) o óleo polar e/ou óleo de silicone está presente dentro de uma membrana de bicamada das vesículas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2010082301 | 2010-03-31 | ||
JP2010220684 | 2010-09-30 | ||
PCT/JP2011/057378 WO2011122477A1 (ja) | 2010-03-31 | 2011-03-25 | ベシクル含有組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012024910A2 true BR112012024910A2 (pt) | 2016-07-05 |
Family
ID=44712184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012024910A BR112012024910A2 (pt) | 2010-03-31 | 2011-03-25 | composição contendo vesícula e método para sua produção |
Country Status (11)
Country | Link |
---|---|
US (1) | US20130028950A1 (pt) |
EP (1) | EP2561862B1 (pt) |
JP (1) | JP4980474B2 (pt) |
KR (1) | KR101344557B1 (pt) |
CN (1) | CN102811708B (pt) |
BR (1) | BR112012024910A2 (pt) |
ES (1) | ES2546986T3 (pt) |
HK (1) | HK1175996A1 (pt) |
RU (1) | RU2517710C1 (pt) |
TW (1) | TWI412378B (pt) |
WO (1) | WO2011122477A1 (pt) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5977107B2 (ja) * | 2012-07-18 | 2016-08-24 | 花王株式会社 | ベシクル組成物の製造方法 |
WO2013122102A1 (ja) * | 2012-02-13 | 2013-08-22 | 花王株式会社 | ベシクル組成物の製造方法 |
JP5988263B2 (ja) * | 2012-09-18 | 2016-09-07 | 国立大学法人京都大学 | 複数の被内包リポソームを内包するリポソーム及びその製造方法 |
JP5690373B2 (ja) | 2013-04-26 | 2015-03-25 | 株式会社 資生堂 | 水性組成物 |
CN103751072B (zh) * | 2014-02-19 | 2015-04-22 | 珀莱雅化妆品股份有限公司 | 一种能恢复皮肤微生态的非离子表面活性剂囊泡及其制备方法 |
KR101655956B1 (ko) * | 2014-10-30 | 2016-09-08 | 서울과학기술대학교 산학협력단 | 유성 화장품의 제거를 위한 w/o 마이크로에멀전 조성물 |
KR101664877B1 (ko) * | 2015-06-26 | 2016-10-12 | 주식회사 코리아나화장품 | 니트로지방산을 함유하는 니오좀을 포함하는 화장료 조성물 |
WO2019082796A1 (ja) * | 2017-10-26 | 2019-05-02 | 株式会社資生堂 | ベシクル含有組成物 |
EP3977983A1 (en) | 2017-10-27 | 2022-04-06 | XYON Health Inc. | Topical formulations for treating dermatological disorders including male pattern baldness |
CN112165929A (zh) * | 2018-06-06 | 2021-01-01 | 株式会社资生堂 | 使用部分交联或交联型二甲基聚硅氧烷的水包油型乳化化妆品 |
KR20230021435A (ko) | 2021-08-05 | 2023-02-14 | (주)아모레퍼시픽 | 난용성 성분이 안정화된 나노베지클을 포함하는 수중유형 화장료 조성물 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5229104A (en) * | 1991-04-29 | 1993-07-20 | Richardson-Vicks Inc. | Artificial tanning compositions containing positively charged paucilamellar vesicles |
FR2725369B1 (fr) * | 1994-10-07 | 1997-01-03 | Oreal | Composition cosmetique ou dermatologique constituee d'une emulsion huile dans eau a base de globules huileux pourvus d'un enrobage cristal liquide lamellaire |
JP3483988B2 (ja) * | 1995-06-01 | 2004-01-06 | 株式会社資生堂 | 皮膚外用剤 |
JP4246980B2 (ja) * | 2001-09-11 | 2009-04-02 | 花王株式会社 | 皮膚外用剤 |
AU2003293350A1 (en) * | 2002-12-04 | 2004-06-23 | Dow Corning Corporation | Vesicle and microemulsion compositions of polar organic oils based on silicone surfactants |
JP2004269430A (ja) * | 2003-03-10 | 2004-09-30 | Ichimaru Pharcos Co Ltd | 毛髪処理用組成物及び損傷毛用毛髪化粧料 |
JP2007533747A (ja) * | 2004-04-20 | 2007-11-22 | ダウ・コーニング・コーポレイション | 活性剤を含むシリコーン小胞 |
US8012387B2 (en) * | 2004-04-20 | 2011-09-06 | Dow Corning Corporation | Silicone vesicles |
JP4611831B2 (ja) * | 2005-07-26 | 2011-01-12 | 株式会社資生堂 | 油中水型皮膚外用剤 |
JP2009513661A (ja) * | 2005-11-01 | 2009-04-02 | ダウ・コーニング・コーポレイション | 活性剤を含むシリコーンベシクル |
JP5121179B2 (ja) * | 2006-07-25 | 2013-01-16 | 株式会社 資生堂 | ベシクル含有組成物及びその製造方法 |
JP5254645B2 (ja) * | 2007-03-13 | 2013-08-07 | 株式会社コーセー | ベシクル組成物及び該ベシクル組成物を配合した皮膚外用剤 |
CN101677914B (zh) * | 2007-05-15 | 2012-06-06 | 株式会社资生堂 | 含泡囊的组合物及其制造方法 |
JP2009242326A (ja) * | 2008-03-31 | 2009-10-22 | Shiseido Co Ltd | 美白液状化粧料 |
JP4395537B2 (ja) * | 2008-04-09 | 2010-01-13 | 株式会社資生堂 | ベシクル及びそれを含む化粧料 |
-
2011
- 2011-03-25 JP JP2011067914A patent/JP4980474B2/ja active Active
- 2011-03-25 CN CN201180016924.5A patent/CN102811708B/zh active Active
- 2011-03-25 BR BR112012024910A patent/BR112012024910A2/pt not_active IP Right Cessation
- 2011-03-25 WO PCT/JP2011/057378 patent/WO2011122477A1/ja active Application Filing
- 2011-03-25 RU RU2012144575/04A patent/RU2517710C1/ru not_active IP Right Cessation
- 2011-03-25 ES ES11762708.3T patent/ES2546986T3/es active Active
- 2011-03-25 EP EP11762708.3A patent/EP2561862B1/en active Active
- 2011-03-25 KR KR1020127027086A patent/KR101344557B1/ko active IP Right Grant
- 2011-03-25 US US13/637,394 patent/US20130028950A1/en not_active Abandoned
- 2011-03-29 TW TW100110716A patent/TWI412378B/zh not_active IP Right Cessation
-
2013
- 2013-03-13 HK HK13103145.3A patent/HK1175996A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP4980474B2 (ja) | 2012-07-18 |
WO2011122477A1 (ja) | 2011-10-06 |
EP2561862B1 (en) | 2015-08-05 |
JP2012092084A (ja) | 2012-05-17 |
EP2561862A1 (en) | 2013-02-27 |
TW201201849A (en) | 2012-01-16 |
HK1175996A1 (en) | 2013-07-19 |
ES2546986T3 (es) | 2015-09-30 |
CN102811708A (zh) | 2012-12-05 |
CN102811708B (zh) | 2014-11-05 |
US20130028950A1 (en) | 2013-01-31 |
KR20130040829A (ko) | 2013-04-24 |
EP2561862A4 (en) | 2013-10-30 |
KR101344557B1 (ko) | 2013-12-26 |
TWI412378B (zh) | 2013-10-21 |
RU2517710C1 (ru) | 2014-05-27 |
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