BR112012016119B1 - método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit - Google Patents

método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit Download PDF

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Publication number
BR112012016119B1
BR112012016119B1 BR112012016119A BR112012016119A BR112012016119B1 BR 112012016119 B1 BR112012016119 B1 BR 112012016119B1 BR 112012016119 A BR112012016119 A BR 112012016119A BR 112012016119 A BR112012016119 A BR 112012016119A BR 112012016119 B1 BR112012016119 B1 BR 112012016119B1
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BR
Brazil
Prior art keywords
sample
kit
sample preparation
detection device
detection method
Prior art date
Application number
BR112012016119A
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English (en)
Portuguese (pt)
Other versions
BR112012016119A2 (pt
Inventor
E Aysta James
J Halverson Kurt
T Kshirsagar Manjiri
Rajagopal Raj
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3M Innovative Properties Co
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Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of BR112012016119A2 publication Critical patent/BR112012016119A2/pt
Publication of BR112012016119B1 publication Critical patent/BR112012016119B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/041Connecting closures to device or container
    • B01L2300/042Caps; Plugs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/04Closures and closing means
    • B01L2300/046Function or devices integrated in the closure
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0672Integrated piercing tool
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0633Valves, specific forms thereof with moving parts
    • B01L2400/0644Valves, specific forms thereof with moving parts rotary valves
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0677Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers
    • B01L2400/0683Valves, specific forms thereof phase change valves; Meltable, freezing, dissolvable plugs; Destructible barriers mechanically breaking a wall or membrane within a channel or chamber
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5021Test tubes specially adapted for centrifugation purposes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5029Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures using swabs
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5082Test tubes per se

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BR112012016119A 2009-12-30 2010-12-30 método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit BR112012016119B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29130109P 2009-12-30 2009-12-30
US33193110P 2010-05-06 2010-05-06
PCT/US2010/062517 WO2011082309A1 (en) 2009-12-30 2010-12-30 Live bioload detection using microparticles

Publications (2)

Publication Number Publication Date
BR112012016119A2 BR112012016119A2 (pt) 2016-05-31
BR112012016119B1 true BR112012016119B1 (pt) 2020-04-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012016119A BR112012016119B1 (pt) 2009-12-30 2010-12-30 método de detecção de células em uma amostra, dispositivo unitário de preparação e detecção de amostra e kit

Country Status (6)

Country Link
US (1) US9284593B2 (https=)
EP (1) EP2519355B1 (https=)
JP (1) JP5972174B2 (https=)
CN (1) CN102770208B (https=)
BR (1) BR112012016119B1 (https=)
WO (1) WO2011082309A1 (https=)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2379226B1 (en) 2008-12-31 2016-04-20 3M Innovative Properties Company Live bioload detection using microparticles
BRPI0918693A2 (pt) 2008-12-31 2016-07-26 3M Innovative Properties Co dispositivos para amostragem e métodos para concentração de microorganismos
US9029100B2 (en) * 2009-12-22 2015-05-12 3M Innovative Properties Company Microorganism concentration process and concentration agent for use therein
EP2658991B1 (en) 2010-12-31 2018-10-10 3M Innovative Properties Company Effervescent compositions and uses thereof
ITUD20110129A1 (it) * 2011-08-10 2013-02-11 Alifax Holding S P A Dispositivo per la raccolta di campioni biologici, e relativo procedimento
US9382569B1 (en) 2012-01-17 2016-07-05 Elemental Scientific, Inc. Fast detection of the presence of a target microbe in a liquid sample
AU2013203281A1 (en) 2012-02-03 2013-08-22 Axxin Pty Ltd Nucleic acid amplification and detection apparatus and method
US10240181B2 (en) * 2012-07-06 2019-03-26 3M Innovative Properties Company Apparatus and methods for detecting ATP in a liquid sample
WO2014060604A2 (en) * 2012-10-20 2014-04-24 Selfdiagnostics OÜ Method and its compositions for detection of nucleic acid target from biological samples and body fluids
KR200488464Y1 (ko) * 2012-12-27 2019-02-07 피티티 글로벌 케미칼 피씨엘 혼합물 또는 용액의 제조 및 전달 장치
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
US10545161B2 (en) 2013-03-11 2020-01-28 Cue Health Inc. Systems and methods for detection and quantification of analytes
AU2014248813B2 (en) 2013-03-11 2016-05-19 Cue Health Inc. Systems and methods for detection and quantification of analytes
KR101390920B1 (ko) * 2013-12-13 2014-04-30 김준우 지방파쇄기 및 지방파쇄가 가능한 성분분리기
USD745423S1 (en) 2014-05-12 2015-12-15 Cue Inc. Automated analyzer test cartridge and sample collection device for analyte detection
WO2016168803A1 (en) * 2015-04-17 2016-10-20 Vax-Immune, LLC Portable disposable re-usable culture device for rapid diagnosis of infectious agents
US11299702B2 (en) * 2015-04-17 2022-04-12 Vax-Immune, LLC Portable disposable re-usable culture device for rapid diagnosis of infectious agents
US9994808B2 (en) * 2015-04-17 2018-06-12 Vax-Immune, LLC Portable disposable re-usable culture device for rapid diagnosis of infectious agents
KR102604091B1 (ko) 2015-07-17 2023-11-22 큐 헬스 인코퍼레이티드 분석물질의 증진된 검출 및 정량을 위한 시스템 및 방법
CN106179552B (zh) * 2016-07-06 2018-09-11 江苏科华医疗器械科技有限公司 一种一体式超滤离心管
WO2018038019A1 (ja) * 2016-08-22 2018-03-01 ユニバーサル・バイオ・リサーチ株式会社 分注用シリンダ、並びに、それを用いた分注装置および分注処理方法
AU2017368329B2 (en) 2016-12-01 2023-11-02 Novel Microdevices, Inc. Automated point-of-care devices for complex sample processing and methods of use thereof
JP6699837B2 (ja) * 2016-12-27 2020-05-27 株式会社フルステム 3次元多孔性足場からの培養細胞回収方法
US10537892B2 (en) * 2017-01-03 2020-01-21 Illumina, Inc. Sample tube with integrated mixing plunger head
US11237161B2 (en) 2017-01-25 2022-02-01 Cue Health Inc. Systems and methods for enhanced detection and quantification of analytes
KR102061651B1 (ko) * 2017-03-03 2020-01-02 사회복지법인 삼성생명공익재단 검체의 전처리 장치 및 이에 의한 검체의 전처리 방법
US10704993B2 (en) * 2017-06-06 2020-07-07 United States Of America As Represented By The Secretary Of The Department Of The Interior Subsurface environment sampler with actuator movable collection chamber
KR102638609B1 (ko) * 2017-07-27 2024-02-19 바이오메리욱스, 인코포레이티드. 격리 튜브
EP3688465B1 (en) * 2017-09-27 2025-11-12 Axxin Pty Ltd Diagnostic test system and method
JP6680742B2 (ja) * 2017-10-31 2020-04-15 大研医器株式会社 磁性粒子収集方法及び試験セット
KR102005366B1 (ko) * 2017-12-19 2019-07-30 한국과학기술원 다공성 복합 나노구조체를 이용한 바이오물질의 포집 및 진단 시스템 및 방법
CN108267496B (zh) * 2017-12-22 2020-06-05 江南大学 一种利用电化学检测活性成分缓释效果的方法
CN108796038B (zh) * 2018-06-26 2019-10-18 杭州优思达生物技术有限公司 一种核酸一体化检测方法及检测试剂管
KR102136695B1 (ko) * 2018-08-22 2020-07-22 주식회사 인퓨전텍 현장 진단용 장치를 이용한 병원체 농축 및 핵산 추출 방법
WO2020077286A1 (en) * 2018-10-12 2020-04-16 Quidel Corporation Extraction reagent for use in an assay for detection of group a streptococcus
CN111175481B (zh) * 2018-11-09 2025-03-04 广州万孚生物技术股份有限公司 血气生化测试卡、血气分析仪及血气分析仪的控制方法
CN113874705B (zh) * 2019-01-07 2024-04-16 1866402安大略有限公司 血液分离及分析装置和方法
TWI683702B (zh) * 2019-01-31 2020-02-01 瑩芳有限公司 採檢容器
KR102788544B1 (ko) * 2019-04-16 2025-03-31 (주)얼라인드제네틱스 애널라이트 수집 장치, 이를 이용한 애널라이트 수집 방법 및 애널라이트 검사 시스템
WO2021086444A1 (en) * 2019-10-29 2021-05-06 Hewlett-Packard Development Company, L.P. Fluid preparation devices
CN116113826B (zh) 2020-09-11 2026-02-27 富士胶片株式会社 浓缩器件、被检体液的浓缩方法、被检体液的检查方法、及检查试剂盒
JP7686786B2 (ja) 2021-12-06 2025-06-02 旭化成株式会社 微生物の濃縮方法及び濃縮容器
USD1045121S1 (en) 2022-06-28 2024-10-01 Vax-Immune, LLC Sample incubation and testing device
USD1045122S1 (en) 2022-06-28 2024-10-01 Vax-Immune, LLC Sample incubation and testing device
USD1069156S1 (en) 2023-04-10 2025-04-01 Becton, Dickinson And Company Dispensing device

Family Cites Families (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL252802A (https=) 1959-11-20
GB1085901A (en) 1964-01-15 1967-10-04 Courtaulds Ltd Fermentation apparatus
US3933592A (en) 1965-02-17 1976-01-20 Hazleton Laboratories, Incorporated Method of detecting living microorganisms
US3745090A (en) 1970-08-04 1973-07-10 Nasa Method of detecting and counting bacteria in body fluids
US4184483A (en) * 1973-05-08 1980-01-22 U.S. Medical Research & Development, Inc. Method of and apparatus for collecting cultures
US3897902A (en) 1974-02-01 1975-08-05 Sindco Corp Phase separating tube
US3971703A (en) 1974-05-31 1976-07-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Method of detecting and counting bacteria
US4144134A (en) 1977-01-31 1979-03-13 Vitatect Corp. Method for detection of bacterial concentration by luminescence
GB1604249A (en) 1977-05-31 1981-12-02 Kolehmainen S Selective measurement of somatic and microbial cells
GB2073885B (en) 1980-04-15 1983-12-21 Whitlock G D Method of and apparatus for detecting the presence of live organisms in substances
GB2138021B (en) 1983-03-29 1987-02-04 Polythene Drums Yeast fermentation
US4503149A (en) 1983-06-06 1985-03-05 Conoco Inc. Method of microbial assay
US4698311A (en) 1985-10-30 1987-10-06 Ortho Diagnostic Systems Inc. Particle washing and separation method
JPS62167221A (ja) 1986-01-17 1987-07-23 Showa Denko Kk レピッドクロサイトの製造方法
US4906565A (en) 1986-03-21 1990-03-06 Minnesota Mining And Manufacturing Company Method for the selective detection of microbial nucleotides
US5238812A (en) 1987-03-13 1993-08-24 Coulter Corporation Method and apparatus for rapid mixing of small volumes for enhancing biological reactions
DK258787D0 (da) 1987-05-21 1987-05-21 Foss Electric As N Fremgangsmaade til bestemmelse af bakteriekoncentration i en proeve
US4978504A (en) * 1988-02-09 1990-12-18 Nason Frederic L Specimen test unit
NZ228374A (en) 1988-03-21 1990-12-21 Du Pont Method for separating and detecting microorganisms from a difficult-to-separate fluid sample, and apparatus therefor
JP3040469B2 (ja) 1990-10-18 2000-05-15 セルプロ インコーポレイテッド 可撓性容器を用いて粒子を分離する装置及び方法
US5264184A (en) 1991-03-19 1993-11-23 Minnesota Mining And Manufacturing Company Device and a method for separating liquid samples
JP3168755B2 (ja) 1993-02-22 2001-05-21 株式会社明電舎 生物固定化担体中の微生物量測定方法
US5576185A (en) 1994-04-15 1996-11-19 Coulter Corporation Method of positive or negative selection of a population or subpopulation of a sample utilizing particles and gravity sedimentation
US5595653A (en) 1994-07-15 1997-01-21 Cera, Inc. Microcolumn for extraction of analytes from liquids
GB9417793D0 (en) 1994-09-05 1994-10-26 Celsis Ltd Bioluminescence and assay reagents
DE19524753A1 (de) 1995-07-07 1997-01-23 Lohmann Therapie Syst Lts Schichttablette zur kontrollierten Freisetzung von Wirkstoffen
US5827675A (en) * 1995-07-12 1998-10-27 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
AU713409B2 (en) 1995-07-12 1999-12-02 Charm Sciences, Inc. Test apparatus, system and method for the detection of test samples
US6140040A (en) 1995-10-06 2000-10-31 Advanced Minerals Corporation Method of mechanically separating microparticles suspended in fluids using particulate media
US6045913A (en) 1995-11-01 2000-04-04 Minnesota Mining And Manufacturing Company At least partly fused particulates and methods of making them by flame fusion
JP3547882B2 (ja) 1995-12-28 2004-07-28 キッコーマン株式会社 Atp消去剤、atp消去法、それを用いた生物細胞測定試薬及び生物細胞測定法
US5908751A (en) 1996-04-26 1999-06-01 Toyo Ink Mfg. Co., Ltd. Method for detecting and/or determining ATP from microorganism cells in a sample
US5905029A (en) 1997-02-19 1999-05-18 Fritz Berthold Method for rapid hygiene testing
JPH1128099A (ja) 1997-05-12 1999-02-02 Kikkoman Corp 黄色ブドウ球菌の検出法
US6451260B1 (en) 1997-08-26 2002-09-17 Dyax Corp. Method for producing microporous elements, the microporous elements thus produced and uses thereof
US6861067B2 (en) 1998-09-17 2005-03-01 Sherwood Services Ag Hydrogel wound dressing and the method of making and using the same
AU1821700A (en) 1998-11-18 2000-06-05 Orchid Biosciences, Inc. One-step nucleic acid dipstick device with movable membrane
DE19856064C2 (de) * 1998-12-04 2000-11-30 Invitek Gmbh Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien
US6174704B1 (en) 1998-12-23 2001-01-16 Pierce Chemical Company Method for recovery of proteins prepared by recombinant DNA procedures
JP3811616B2 (ja) 1999-05-25 2006-08-23 ミリポア・コーポレイション 哺乳動物細胞調製物中の微生物を、atp生物発光を利用して迅速に検出して計数する方法
US7223364B1 (en) 1999-07-07 2007-05-29 3M Innovative Properties Company Detection article having fluid control film
US7109315B2 (en) * 2000-03-15 2006-09-19 Bruce J. Bryan Renilla reniformis fluorescent proteins, nucleic acids encoding the fluorescent proteins and the use thereof in diagnostics, high throughput screening and novelty items
US6660489B2 (en) 2000-12-01 2003-12-09 Becton, Dickinson And Company ATP extraction method
CA2431097A1 (en) 2000-12-22 2002-07-04 Bio A.R.T. Bvba Flow through assay device, diagnostic kit comprising said assay device and use of said assay device in the detection of an analyte present in a sample
US7083911B2 (en) 2001-02-16 2006-08-01 Promega Corporation Method for detection of ATP
US6824560B2 (en) 2001-06-13 2004-11-30 Advanced Cardiovascular Systems, Inc. Double-butted superelastic nitinol tubing
CN1514739A (zh) 2001-06-29 2004-07-21 具有气味控制性能的高吸水性含羧基聚合物和制备方法
WO2003004138A1 (en) 2001-07-02 2003-01-16 Health Dynamics Institute Appliance for recovering solid component in liquid sample
US6588681B2 (en) 2001-07-09 2003-07-08 3M Innovative Properties Company Liquid supply assembly
US6967261B1 (en) 2001-12-28 2005-11-22 Kimberly-Clark Worldwide Bandage, methods of producing and using same
US7005143B2 (en) 2002-04-12 2006-02-28 3M Innovative Properties Company Gel materials, medical articles, and methods
US7832566B2 (en) 2002-05-24 2010-11-16 Biomet Biologics, Llc Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles
AU2003243627A1 (en) 2002-06-18 2003-12-31 Ingersoll-Rand Energy Systems Corporation Microturbine engine system
US20040124085A1 (en) 2002-06-26 2004-07-01 California Institute Of Technology Microfluidic devices and methods with electrochemically actuated sample processing
US20040197845A1 (en) * 2002-08-30 2004-10-07 Arjang Hassibi Methods and apparatus for pathogen detection, identification and/or quantification
EP1603674B1 (en) 2003-02-05 2016-01-06 Iquum, Inc. Sample processing
JP4364562B2 (ja) 2003-06-19 2009-11-18 株式会社メガチップス 映像記録システムにおけるカメラ管理方法
US20060194207A1 (en) 2003-07-30 2006-08-31 Riken Kit for detecting nucleic acids
CA2535153A1 (en) 2003-08-12 2005-05-19 Massachusetts Institute Of Technology Sample preparation methods and devices
US7338692B2 (en) 2003-09-12 2008-03-04 3M Innovative Properties Company Microporous PVDF films
JP4378608B2 (ja) 2003-09-26 2009-12-09 Dic株式会社 土木建築材用被覆組成物、舗装材及びこれを用いた舗装体
US20050070701A1 (en) 2003-09-29 2005-03-31 Hochstetler Spencer Erich Detection of living cells in polymers or pigments
US20050142571A1 (en) * 2003-12-24 2005-06-30 3M Innovative Properties Company Methods for nucleic acid isolation and kits using solid phase material
US20050152992A1 (en) 2004-01-13 2005-07-14 Johnson Loyal M.Jr. Antimicrobial surface preparation and method for producing the same
US7141033B2 (en) 2004-01-16 2006-11-28 Andx, Inc Sample collection device and method
GB0401288D0 (en) * 2004-01-21 2004-02-25 Orion Diagnostica Oy Sampling and assay device
ITRM20040168A1 (it) 2004-04-01 2004-07-01 Sigma Tau Ind Farmaceuti Composizione a rilascio modificato ph dipendente.
US20050250138A1 (en) 2004-05-04 2005-11-10 Millipore Corporation Process for the enumeration and identification of microorganisms
EP1763584B1 (en) 2004-07-02 2009-04-22 Promega Corporation Compositions and processes for the extraction and detection of microbial atp
RU2396548C2 (ru) 2004-07-02 2010-08-10 БАЙЕР ХЕЛТКЭР ЭлЭлСи Световодный тестовый датчик для определения исследуемого вещества в пробе флюида (варианты) и способы его изготовления (варианты)
US7282181B2 (en) 2004-09-16 2007-10-16 Varian Inc. Fluid collection and testing device
US20060062854A1 (en) 2004-09-22 2006-03-23 Noble Fiber Technologies, Llc Hydrogel having anti-microbial properties
WO2006069053A2 (en) * 2004-12-22 2006-06-29 Charm Sciences, Inc. Sampling method and device
US20060166347A1 (en) * 2005-01-27 2006-07-27 Applera Corporation Sample preparation devices and methods
US7485609B2 (en) 2005-09-29 2009-02-03 Kimberly-Clark Worldwide, Inc. Encapsulated liquid cleanser
GB2433219A (en) 2005-12-16 2007-06-20 Diasys Europ Ltd A filtering device
US7824732B2 (en) 2005-12-28 2010-11-02 3M Innovative Properties Company Encapsulated chromonic particles
CN101351337B (zh) 2005-12-30 2011-07-27 3M创新有限公司 功能性基底
US20080023408A1 (en) 2006-01-13 2008-01-31 Vanson Halosource, Inc. Catch basin insert for treating storm water
GB0606822D0 (en) 2006-04-05 2006-05-17 Alaska Food Diagnostics Assay System
US20070269341A1 (en) 2006-05-22 2007-11-22 3M Innovative Properties Company Sampling assembly and method of preparing samples
WO2007137257A2 (en) 2006-05-22 2007-11-29 3M Innovative Properties Company System and method for preparing samples
BRPI0712183A2 (pt) 2006-06-08 2012-01-17 3M Innovative Properties Co microesferas poliméricas e métodos de preparo de microesferas poliméricas
US20080153125A1 (en) 2006-11-10 2008-06-26 Advanced Analytical Technologies, Inc. Rapid detection of microorganisms in fluids
GB0625309D0 (en) 2006-12-19 2007-01-24 Inverness Medical Switzerland Device
US7939578B2 (en) 2007-02-23 2011-05-10 3M Innovative Properties Company Polymeric fibers and methods of making
WO2008122908A1 (en) 2007-04-04 2008-10-16 Koninklijke Philips Electronics N.V. Method and device for gathering a fluid sample for screening purposes
EP2137533A2 (en) 2007-04-19 2009-12-30 3M Innovative Properties Company Uses of water-dispersible silica nanoparticles for attaching biomolecules
WO2008129517A2 (en) 2007-04-23 2008-10-30 Ranbaxy Laboratories Limited A stabilized delayed release pharmaceutical composition of rabeprazole
WO2008134472A1 (en) 2007-04-25 2008-11-06 3M Innovative Properties Company Compositions, methods, and devices for isolating biological materials
US20100297691A1 (en) 2007-05-31 2010-11-25 Ribeiro Alice Maria M Devices and processes for collecting and concentrating samples for microbiological analysis
US7829020B2 (en) 2007-08-02 2010-11-09 Lawrence Livermore National Laboratory, Llc Simple, field portable colorimetric detection device for organic peroxides and hydrogen peroxide
WO2009085357A2 (en) 2007-10-03 2009-07-09 3M Innovative Properties Company Microorganism concentration process
BRPI0817422A8 (pt) 2007-10-03 2019-01-29 3M Innovative Properties Co processo de concentração de microorganismos
EP3167958A1 (en) 2007-10-03 2017-05-17 3M Innovative Properties Company Process for preparing microorganism concentration agent
JP5451622B2 (ja) 2007-10-03 2014-03-26 スリーエム イノベイティブ プロパティズ カンパニー 微生物の増殖を制限するための方法
JP5524849B2 (ja) 2007-10-11 2014-06-18 スリーエム イノベイティブ プロパティズ カンパニー 比較的大きな平均孔径を有する微多孔性膜及びその製造方法
WO2009061864A1 (en) 2007-11-06 2009-05-14 3M Innovative Properties Company Processing device tablet
JP2011502545A (ja) 2007-11-20 2011-01-27 スリーエム イノベイティブ プロパティズ カンパニー 試料調製容器及び方法
WO2009067513A1 (en) 2007-11-20 2009-05-28 3M Innovative Properties Company Sample preparation container and method
WO2009067503A1 (en) 2007-11-20 2009-05-28 3M Innovative Properties Company Sample preparation for environmental sampling
JP2011505550A (ja) 2007-11-20 2011-02-24 スリーエム イノベイティブ プロパティズ カンパニー 試料を調製及び収集するためのシステム及び方法
JP5330404B2 (ja) 2007-12-12 2013-10-30 スリーエム イノベイティブ プロパティズ カンパニー 微小構造化された抗微生物フィルム
JP5420566B2 (ja) 2007-12-21 2014-02-19 スリーエム イノベイティブ プロパティズ カンパニー 微生物系及び流体試料分析の方法
EP2250188B1 (en) 2008-02-14 2014-06-11 3M Innovative Properties Company Polypeptides for microbial detection
EP2250503A2 (en) 2008-02-20 2010-11-17 3M Innovative Properties Company Methods of analyzing samples for bacteria using whole cell capture and atp analysis
GB0808557D0 (en) * 2008-05-13 2008-06-18 3M Innovative Properties Co Sampling devices and methods of use
CN102245755B (zh) 2008-09-30 2013-11-06 3M创新有限公司 生物检测制品
BRPI0918693A2 (pt) 2008-12-31 2016-07-26 3M Innovative Properties Co dispositivos para amostragem e métodos para concentração de microorganismos
EP2379226B1 (en) 2008-12-31 2016-04-20 3M Innovative Properties Company Live bioload detection using microparticles
WO2010078404A1 (en) 2008-12-31 2010-07-08 3M Innovative Properties Company Methods, kits and systems for processing samples
WO2010129727A1 (en) 2009-05-06 2010-11-11 3M Innovative Properties Company Coated substrates comprising a cell extractant and biodetection methods thereof
US20120082977A1 (en) 2009-05-06 2012-04-05 Raj Rajagopal Articles with matrix comprising a cell extractant and biodetection methods thereof
US20120094281A1 (en) 2009-05-06 2012-04-19 Raj Rajagopal Articles with shell structures including a cell extractant and biodetection methods thereof
US9029100B2 (en) 2009-12-22 2015-05-12 3M Innovative Properties Company Microorganism concentration process and concentration agent for use therein

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JP2013516179A (ja) 2013-05-13
WO2011082309A1 (en) 2011-07-07
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