BR112012002594B1 - dispositivo e método para detectar sangue ou constituintes de sangue no sistema de líquido de um dispositivo para tratamento de sangue extracorpóreo - Google Patents
dispositivo e método para detectar sangue ou constituintes de sangue no sistema de líquido de um dispositivo para tratamento de sangue extracorpóreo Download PDFInfo
- Publication number
- BR112012002594B1 BR112012002594B1 BR112012002594A BR112012002594A BR112012002594B1 BR 112012002594 B1 BR112012002594 B1 BR 112012002594B1 BR 112012002594 A BR112012002594 A BR 112012002594A BR 112012002594 A BR112012002594 A BR 112012002594A BR 112012002594 B1 BR112012002594 B1 BR 112012002594B1
- Authority
- BR
- Brazil
- Prior art keywords
- intensity
- blood
- component
- light
- fluid
- Prior art date
Links
- 210000004369 blood Anatomy 0.000 title claims abstract description 224
- 239000008280 blood Substances 0.000 title claims abstract description 224
- 238000000034 method Methods 0.000 title claims abstract description 24
- 239000000470 constituent Substances 0.000 title claims abstract description 21
- 239000007788 liquid Substances 0.000 title abstract description 9
- 206010018910 Haemolysis Diseases 0.000 claims abstract description 62
- 230000008588 hemolysis Effects 0.000 claims abstract description 62
- 108010054147 Hemoglobins Proteins 0.000 claims abstract description 33
- 102000001554 Hemoglobins Human genes 0.000 claims abstract description 33
- 239000012528 membrane Substances 0.000 claims abstract description 22
- 230000007547 defect Effects 0.000 claims abstract description 15
- 239000012530 fluid Substances 0.000 claims description 128
- 238000011156 evaluation Methods 0.000 claims description 62
- 150000001875 compounds Chemical class 0.000 claims description 3
- 238000000502 dialysis Methods 0.000 abstract 4
- 230000017531 blood circulation Effects 0.000 abstract 2
- 230000004069 differentiation Effects 0.000 abstract 1
- 239000000385 dialysis solution Substances 0.000 description 39
- 238000005259 measurement Methods 0.000 description 18
- 238000002615 hemofiltration Methods 0.000 description 7
- 230000009885 systemic effect Effects 0.000 description 7
- 230000006870 function Effects 0.000 description 6
- 238000001631 haemodialysis Methods 0.000 description 6
- 230000000322 hemodialysis Effects 0.000 description 6
- 230000003287 optical effect Effects 0.000 description 6
- 230000006378 damage Effects 0.000 description 5
- 230000008033 biological extinction Effects 0.000 description 4
- 238000001514 detection method Methods 0.000 description 4
- 210000003743 erythrocyte Anatomy 0.000 description 4
- 230000002159 abnormal effect Effects 0.000 description 3
- 238000012937 correction Methods 0.000 description 3
- 238000000691 measurement method Methods 0.000 description 3
- 238000012544 monitoring process Methods 0.000 description 3
- 230000035945 sensitivity Effects 0.000 description 3
- 230000006978 adaptation Effects 0.000 description 2
- 230000002950 deficient Effects 0.000 description 2
- 238000001228 spectrum Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000011144 upstream manufacturing Methods 0.000 description 2
- 241001631457 Cannula Species 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 230000036770 blood supply Effects 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 108010036302 hemoglobin AS Proteins 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 238000012806 monitoring device Methods 0.000 description 1
- 230000005693 optoelectronics Effects 0.000 description 1
- 102000028703 oxygen binding proteins Human genes 0.000 description 1
- 108091009355 oxygen binding proteins Proteins 0.000 description 1
- 230000011664 signaling Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1692—Detection of blood traces in dialysate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/251—Colorimeters; Construction thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/18—General characteristics of the apparatus with alarm
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3306—Optical measuring means
- A61M2205/3313—Optical measuring means used specific wavelengths
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Vascular Medicine (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Biophysics (AREA)
- Ecology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- External Artificial Organs (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102009036044A DE102009036044A1 (de) | 2009-08-04 | 2009-08-04 | Vorrichtung und Verfahren zur Erkennung von Blut oder Blutbestandteilen im Flüssigkeitssystem einer Vorrichtung zur extrakorporalen Blutbehandlung |
| PCT/EP2010/004697 WO2011015321A1 (de) | 2009-08-04 | 2010-07-31 | Vorrichtung und verfahren zur erkennung von blut oder blutbestandteilen im flüssigkeitssystem einer vorrichtung zur extrakorporalen blutbehandlung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112012002594A2 BR112012002594A2 (pt) | 2016-03-22 |
| BR112012002594B1 true BR112012002594B1 (pt) | 2020-02-04 |
Family
ID=43014525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112012002594A BR112012002594B1 (pt) | 2009-08-04 | 2010-07-31 | dispositivo e método para detectar sangue ou constituintes de sangue no sistema de líquido de um dispositivo para tratamento de sangue extracorpóreo |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8743353B2 (enExample) |
| EP (1) | EP2461844B1 (enExample) |
| JP (1) | JP5678061B2 (enExample) |
| CN (1) | CN102548594B (enExample) |
| AU (1) | AU2010281016B2 (enExample) |
| BR (1) | BR112012002594B1 (enExample) |
| DE (1) | DE102009036044A1 (enExample) |
| EA (1) | EA027286B1 (enExample) |
| IN (1) | IN2012DN00732A (enExample) |
| WO (1) | WO2011015321A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102010034626A1 (de) * | 2010-08-17 | 2012-02-23 | B. Braun Avitum Ag | Vorrichtung zur extrakorporalen Blutbehandlung |
| JP5816014B2 (ja) * | 2011-07-14 | 2015-11-17 | 旭化成メディカル株式会社 | 血漿浄化装置及び血漿浄化装置の作動方法 |
| JP5808653B2 (ja) * | 2011-11-18 | 2015-11-10 | シスメックス株式会社 | 血球計数装置および血球計数方法 |
| JP6250053B2 (ja) | 2012-09-04 | 2017-12-20 | フェンウォール、インコーポレイテッド | 血液処理システムの境界検知装置 |
| CN104363935B (zh) | 2012-12-14 | 2017-06-20 | 甘布罗伦迪亚股份公司 | 利用位置感测的用于压力匣的隔膜重新定位 |
| DE102013103335A1 (de) * | 2013-04-03 | 2014-10-09 | B. Braun Avitum Ag | System zur Erfassung eines Zustands einer Dialysatorvorrichtung, und hierfür verwendbare Sensorvorrichtung |
| DE102013104501A1 (de) * | 2013-05-02 | 2014-11-06 | B. Braun Avitum Ag | Vorrichtung zur extrakorporalen Blutbehandlung |
| DE102013112038A1 (de) * | 2013-10-31 | 2015-04-30 | Fresenius Medical Care AG & Co. KGaA | Blutbehandlungsvorrichtung mit erhöhter Patientensicherheit und Verfahren |
| JP6385095B2 (ja) * | 2014-03-26 | 2018-09-05 | 旭化成メディカル株式会社 | 血液浄化装置 |
| US10172989B2 (en) | 2014-09-12 | 2019-01-08 | Easydial Inc. | Portable hemodialysis machine and disposable cartridge with blood leak sensor |
| US10980929B2 (en) | 2014-09-12 | 2021-04-20 | Diality Inc. | Hemodialysis system with ultrafiltration controller |
| DE102016107024A1 (de) * | 2016-04-15 | 2017-10-19 | B. Braun Avitum Ag | Verfahren und Vorrichtung zur extrakorporalen Blutbehandlung |
| CN106404721B (zh) * | 2016-08-25 | 2019-05-03 | 吴小戈 | 一种血液浓度检测装置 |
| DE102017000226A1 (de) * | 2017-01-13 | 2018-07-19 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zur Erkennung von Blut oder eines Blutbestandteils oder der Bestimmung der Konzentration von Blut oder eines Blutbestandteils in einer Flüssigkeit |
| CN108007886A (zh) * | 2017-12-27 | 2018-05-08 | 北京哈特凯尔医疗科技有限公司 | 一种基于双波长检测液体中血液含量的检测装置和检测方法 |
| DE102018205387A1 (de) * | 2018-04-10 | 2019-10-10 | Fresenius Medical Care Deutschland Gmbh | Vorrichtung und Verfahren zur Bestimmung von Restblut in einem Dialysator sowie Dialysesystem |
| CN110694129A (zh) * | 2019-09-06 | 2020-01-17 | 广东宝莱特医用科技股份有限公司 | 一种血液检测装置及方法 |
| CN112051264B (zh) * | 2020-06-13 | 2021-06-01 | 中南大学湘雅医院 | 透析废液血红蛋白检测平台 |
| CN116942941B (zh) * | 2023-09-14 | 2023-12-29 | 苏州森斯缔夫传感科技有限公司 | 一种光强比照传感器、方法及血液净化机 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5911864B2 (ja) * | 1975-07-14 | 1984-03-19 | 武田薬品工業株式会社 | 漏血検知装置 |
| US4166961A (en) * | 1978-03-22 | 1979-09-04 | Hoechst Aktiengesellschaft | Method and apparatus for detecting a blood leak in a hemodialysis system |
| JPS62838A (ja) | 1985-06-26 | 1987-01-06 | Kawasumi Lab Inc | 溶血測定装置 |
| US5486286A (en) * | 1991-04-19 | 1996-01-23 | Althin Medical, Inc. | Apparatus for performing a self-test of kidney dialysis membrane |
| ATE244585T1 (de) * | 1992-11-12 | 2003-07-15 | Baxter Int | Verfahren und gerät für dialyse |
| US6348156B1 (en) * | 1999-09-03 | 2002-02-19 | Baxter International Inc. | Blood processing systems and methods with sensors to detect contamination due to presence of cellular components or dilution due to presence of plasma |
| US6947131B2 (en) * | 2002-05-07 | 2005-09-20 | Chf Solutions, Inc. | Blood leak detector for extracorporeal treatment system |
| AU2004254632B2 (en) * | 2003-07-02 | 2009-02-12 | Terumo Bct, Inc. | Monitoring and control system for blood processing |
| US7671974B2 (en) * | 2003-10-29 | 2010-03-02 | Chf Solutions Inc. | Cuvette apparatus and system for measuring optical properties of a liquid such as blood |
| DE202004003335U1 (de) * | 2004-03-03 | 2004-06-09 | Christian Doppler Labor für spezifische Adsorptionstechnologien in der Medizin/Donau-Universität Krems | Vorrichtung zur Messung optischer Eigenschaften eines Filtratfusses |
| US20090257061A1 (en) * | 2005-11-25 | 2009-10-15 | Nils Wihlborg | Optical Analyzer |
| US7790464B2 (en) | 2006-05-04 | 2010-09-07 | Blaze Medical Devices, LLC | Blood hemolysis analyzer |
| DE102006029899B4 (de) * | 2006-06-29 | 2009-06-04 | Fresenius Medical Care Deutschland Gmbh | Spektroskopischer Detektor und Verfahren zur Bestimmung von Blut und biologischen Markersubstanzen in Flüssigkeiten |
| US8130369B2 (en) * | 2008-11-05 | 2012-03-06 | Fresenius Medical Care Holdings, Inc. | Measuring hematocrit and estimating hemoglobin values with a non-invasive, optical blood monitoring system |
| JP5278681B2 (ja) * | 2009-01-28 | 2013-09-04 | メディカテック株式会社 | 透析装置のセンサ装置 |
-
2009
- 2009-08-04 DE DE102009036044A patent/DE102009036044A1/de not_active Ceased
-
2010
- 2010-07-31 US US13/388,603 patent/US8743353B2/en not_active Expired - Fee Related
- 2010-07-31 WO PCT/EP2010/004697 patent/WO2011015321A1/de not_active Ceased
- 2010-07-31 BR BR112012002594A patent/BR112012002594B1/pt not_active IP Right Cessation
- 2010-07-31 EP EP10747579.0A patent/EP2461844B1/de not_active Not-in-force
- 2010-07-31 JP JP2012523234A patent/JP5678061B2/ja not_active Expired - Fee Related
- 2010-07-31 CN CN201080034586.3A patent/CN102548594B/zh not_active Expired - Fee Related
- 2010-07-31 AU AU2010281016A patent/AU2010281016B2/en not_active Ceased
- 2010-07-31 EA EA201270235A patent/EA027286B1/ru not_active IP Right Cessation
- 2010-07-31 IN IN732DEN2012 patent/IN2012DN00732A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2013500800A (ja) | 2013-01-10 |
| US20120170020A1 (en) | 2012-07-05 |
| AU2010281016A1 (en) | 2012-02-23 |
| CN102548594A (zh) | 2012-07-04 |
| BR112012002594A2 (pt) | 2016-03-22 |
| EA027286B1 (ru) | 2017-07-31 |
| EA201270235A1 (ru) | 2012-07-30 |
| DE102009036044A1 (de) | 2011-02-10 |
| JP5678061B2 (ja) | 2015-02-25 |
| CN102548594B (zh) | 2014-10-22 |
| WO2011015321A1 (de) | 2011-02-10 |
| IN2012DN00732A (enExample) | 2015-06-19 |
| US8743353B2 (en) | 2014-06-03 |
| EP2461844A1 (de) | 2012-06-13 |
| EP2461844B1 (de) | 2013-12-11 |
| AU2010281016B2 (en) | 2015-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112012002594B1 (pt) | dispositivo e método para detectar sangue ou constituintes de sangue no sistema de líquido de um dispositivo para tratamento de sangue extracorpóreo | |
| TW200413040A (en) | The blood purifier | |
| TWI352604B (en) | Blood purification device | |
| US7618531B2 (en) | Hemodialysis treatment apparatus and method for hemodialysis treatment | |
| TWI450738B (zh) | 血液淨化裝置 | |
| JP4959229B2 (ja) | 血液ライン内圧力を監視するシステム及びそれに使用される装置 | |
| CN100486649C (zh) | 血细胞比容传感器 | |
| CN110494749B (zh) | 盐或血液或两者混合物中的气泡的光学检测 | |
| EP3042672B1 (en) | Blood purification apparatus | |
| CA2784524C (en) | Apparatus for extracorporeal blood treatment and method of operation | |
| CN106030303B (zh) | 自校准血室 | |
| JP2011512212A (ja) | 血液処理装置の作動方法、並びに本方法を実施する血液量モニタ及び血液処理装置 | |
| CN109475672B (zh) | 用于执行血液处理机的连接测试的方法及控制装置 | |
| CN113975508A (zh) | 血液净化设备的故障确定方法、血液净化设备及存储介质 | |
| US10940257B2 (en) | Systems and methods for oxygenator performance evaluation | |
| JP7021128B2 (ja) | 血液治療装置の透析液排出ラインにおいて血液を検出する制御ユニット及び血液治療装置 | |
| CN100548392C (zh) | 血液净化装置 | |
| CN112040998B (zh) | 具有漏血传感器的透析设备 | |
| CN100441243C (zh) | 血液净化装置 | |
| US20250295334A1 (en) | Blood monitoring systems and methods | |
| JPH0363065A (ja) | 人工透析装置 | |
| JP2024060177A (ja) | 透析器用血流計測表示装置 | |
| JP2023007642A (ja) | 体外循環装置 | |
| JP2022158019A (ja) | ヘマトクリットセンサおよびヘマトクリット測定方法 | |
| CN114901323A (zh) | 血容量变化的透析中监测 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 31/07/2010, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2681 DE 24-05-2022 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |