BR112012001998B8 - solução oftálmica, uso de um composto, e, método para preparação de uma solução oftálmica - Google Patents

solução oftálmica, uso de um composto, e, método para preparação de uma solução oftálmica

Info

Publication number
BR112012001998B8
BR112012001998B8 BR112012001998A BR112012001998A BR112012001998B8 BR 112012001998 B8 BR112012001998 B8 BR 112012001998B8 BR 112012001998 A BR112012001998 A BR 112012001998A BR 112012001998 A BR112012001998 A BR 112012001998A BR 112012001998 B8 BR112012001998 B8 BR 112012001998B8
Authority
BR
Brazil
Prior art keywords
ophthalmic solution
compound
preparing
ophthalmic
keratoconus
Prior art date
Application number
BR112012001998A
Other languages
English (en)
Other versions
BR112012001998A2 (pt
BR112012001998B1 (pt
Inventor
Del Prete Antonio
Caruso Ciro
Troisi Salvatore
Original Assignee
Del Prete Antonio
Caruso Ciro
Renato Sanseverino
Troisi Salvatore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT000052A external-priority patent/ITVA20090052A1/it
Priority claimed from IT000044A external-priority patent/ITVA20100044A1/it
Application filed by Del Prete Antonio, Caruso Ciro, Renato Sanseverino, Troisi Salvatore filed Critical Del Prete Antonio
Publication of BR112012001998A2 publication Critical patent/BR112012001998A2/pt
Publication of BR112012001998B1 publication Critical patent/BR112012001998B1/pt
Publication of BR112012001998B8 publication Critical patent/BR112012001998B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4415—Pyridoxine, i.e. Vitamin B6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51—Thiamines, e.g. vitamin B1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Abstract

solução oftálmica, uso de um composto, e, método para preparação de uma solução oftálmica uma solução oftálmica contendo riboflavina e pelo menos um composto escolhido no grupo composto de aminoácidos essenciais e condicionalmente essenciais, coenzima q, l-prolina, glicina, cloridrato de lisina, l-leucina, l-arginina e compostos intencionados para a produção de metaloproteinase mmp9 para a proteção de estruturas internas do globo ocular contra raios uv-a ou para o tratamento de ceratocone com uma técnica de reticulação trans-epitelial.
BR112012001998A 2009-07-27 2010-07-23 solução oftálmica, uso de um composto, e, método para preparação de uma solução oftálmica BR112012001998B8 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
ITVA2009A000052 2009-07-27
IT000052A ITVA20090052A1 (it) 2009-07-27 2009-07-27 Composizione per il trattamento del cheratocono con tecnica di cross-linking trans-epiteliale o per proteggere strutture interne del globo oculare da raggi uv-a
ITVA2010A000044 2010-05-20
IT000044A ITVA20100044A1 (it) 2010-05-20 2010-05-20 Soluzione oftalmica per proteggere strutture interne del globo oculare da raggi uv-a o per il trattamento del cheratocono con tecnica di cross-linking trans-epiteliale
PCT/EP2010/060752 WO2011012557A1 (en) 2009-07-27 2010-07-23 Ophthalmic solution for protecting internal structures of the eyeball against uv-a rays or for the treatment of keratoconus with a trans-epithelial cross-linking technique

Publications (3)

Publication Number Publication Date
BR112012001998A2 BR112012001998A2 (pt) 2017-01-31
BR112012001998B1 BR112012001998B1 (pt) 2020-12-01
BR112012001998B8 true BR112012001998B8 (pt) 2021-05-25

Family

ID=42575807

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012001998A BR112012001998B8 (pt) 2009-07-27 2010-07-23 solução oftálmica, uso de um composto, e, método para preparação de uma solução oftálmica

Country Status (13)

Country Link
US (1) US9192594B2 (pt)
EP (1) EP2459186B1 (pt)
JP (1) JP2013500302A (pt)
KR (1) KR20120038520A (pt)
CN (1) CN102470120A (pt)
AU (1) AU2010277668A1 (pt)
BR (1) BR112012001998B8 (pt)
CA (1) CA2805511C (pt)
ES (1) ES2441227T3 (pt)
PT (1) PT2459186E (pt)
RU (1) RU2540481C2 (pt)
WO (1) WO2011012557A1 (pt)
ZA (1) ZA201201122B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
US9023092B2 (en) 2011-08-23 2015-05-05 Anthony Natale Endoscopes enhanced with pathogenic treatment
WO2013028833A1 (en) 2011-08-23 2013-02-28 Anthony Natale Systems and methods for treating pathogenic infection
CN102429767B (zh) * 2011-08-25 2016-03-09 广东福地新视野光电技术有限公司 激光角膜热成形术系统
ITMI20120355A1 (it) * 2012-03-07 2013-09-08 Ciro Caruso Sostanza colorante per uso diagnostico oftalmologico
WO2013148896A1 (en) 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Ocular treatment solutions, delivery devices and delivery augmentation methods
US9555111B2 (en) 2012-03-29 2017-01-31 Cxl Ophthalmics, Llc Ocular cross-linking system and method for sealing corneal wounds
EP2830637A4 (en) 2012-03-29 2016-03-16 Cxl Ophthalmics Llc COMPOSITIONS AND METHODS FOR TREATING OR PREVENTING DISEASES RELATED TO OXIDATIVE STRESS
ITRM20130248A1 (it) * 2013-04-24 2014-10-25 Medivis S R L Formulazioni di riboflavina per il cross-linking transepiteliale.
RU2683651C2 (ru) * 2013-06-18 2019-04-01 Иван Дмитриевич Захаров Лекарственное средство для лечения кератоконуса и других дегенеративных заболеваний роговицы и фармацевтические препараты на его основе
US9931199B2 (en) * 2014-05-05 2018-04-03 Roberto Gustavo ALBERTAZZI Methods and apparatus for treating keratoconus
RU2556791C1 (ru) * 2014-06-09 2015-07-20 федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Способ лечения кератоконуса
EP3324973B1 (en) * 2015-07-21 2020-06-03 Avedro, Inc. Treament of an eye with a photosensitizer
US20180236077A1 (en) * 2017-02-21 2018-08-23 Avedro, Inc. Formulations for eye treatments

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106669A (zh) 1994-10-10 1995-08-16 华中理工大学 一种防治白内障的滴眼液
US5780446A (en) * 1996-07-09 1998-07-14 Baylor College Of Medicine Formulations of vesicant drugs and methods of use thereof
ITMI981586A1 (it) * 1998-07-10 2000-01-10 Giorgio Panin Vitamina e e suoi esteri per l'uso nel trattamento topico di patologie delle mucose
US6291519B1 (en) * 1998-10-14 2001-09-18 Novartis Ag Method of preventing damage to eye tissue
IT1307281B1 (it) * 1999-11-25 2001-10-30 Simonelli Giuseppe Uso di ubichinone q10 per il trattamento locale e la prevenzione dipatalogie oftalmologiche secondarie alla terapia fotorefrattiva,
US6441050B1 (en) 2000-08-29 2002-08-27 Raj K. Chopra Palatable oral coenzyme Q liquid
RU2201213C1 (ru) * 2001-07-04 2003-03-27 Общество с ограниченной ответственностью "Научно-экспериментальное производство Микрохирургия глаза" Глазные капли "карнозин"
JP5147156B2 (ja) * 2003-08-08 2013-02-20 ロート製薬株式会社 角膜障害抑制剤
GB0404693D0 (en) * 2004-03-02 2004-04-07 Univ London Pharmaceutical preparations for the treatment of ocular surface and other disorders
JP4604515B2 (ja) * 2004-03-05 2011-01-05 大正製薬株式会社 眼科用剤
ITMI20052036A1 (it) * 2005-10-26 2007-04-27 Professional Dietetics Srl Composizioni farmaceutiche oftalmiche a base di amminoacidi e sodio ialuronato
ITRM20070356A1 (it) * 2007-06-26 2008-12-27 Sooft Italia Srl Soluzione oculare sterile monouso e suo procedimento di produzione per il cross linking corneale del cheratocono

Also Published As

Publication number Publication date
US20120121567A1 (en) 2012-05-17
EP2459186A1 (en) 2012-06-06
CA2805511A1 (en) 2011-02-03
JP2013500302A (ja) 2013-01-07
AU2010277668A1 (en) 2012-03-01
CN102470120A (zh) 2012-05-23
ES2441227T3 (es) 2014-02-03
BR112012001998A2 (pt) 2017-01-31
CA2805511C (en) 2017-04-11
BR112012001998B1 (pt) 2020-12-01
US9192594B2 (en) 2015-11-24
ZA201201122B (en) 2013-05-29
AU2010277668A8 (en) 2012-04-19
KR20120038520A (ko) 2012-04-23
PT2459186E (pt) 2013-12-24
EP2459186B1 (en) 2013-10-09
RU2012106178A (ru) 2013-09-10
WO2011012557A1 (en) 2011-02-03
RU2540481C2 (ru) 2015-02-10

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
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B06T Formal requirements before examination [chapter 6.20 patent gazette]
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B16A Patent or certificate of addition of invention granted

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 01/12/2020, OBSERVADAS AS CONDICOES LEGAIS.

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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 23/07/2010 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF