BR0318269A - composições, alvos, métodos e dispositivos para a terapia de distúrbios oculares e perioculares - Google Patents
composições, alvos, métodos e dispositivos para a terapia de distúrbios oculares e periocularesInfo
- Publication number
- BR0318269A BR0318269A BRPI0318269-0A BR0318269A BR0318269A BR 0318269 A BR0318269 A BR 0318269A BR 0318269 A BR0318269 A BR 0318269A BR 0318269 A BR0318269 A BR 0318269A
- Authority
- BR
- Brazil
- Prior art keywords
- periocular
- disorders
- methods
- targets
- therapy
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 210000003205 muscle Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/421,956 US20040058313A1 (en) | 2002-04-24 | 2003-04-24 | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
| PCT/US2003/038740 WO2004096183A1 (en) | 2003-04-24 | 2003-12-08 | Compositions, targets, methods and devices for the therapy of ocular and periocular disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0318269A true BR0318269A (pt) | 2006-05-23 |
Family
ID=33415845
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0318269-0A BR0318269A (pt) | 2003-04-24 | 2003-12-08 | composições, alvos, métodos e dispositivos para a terapia de distúrbios oculares e perioculares |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US20040058313A1 (https=) |
| EP (1) | EP1622589B1 (https=) |
| JP (1) | JP2006524185A (https=) |
| AU (1) | AU2003297684A1 (https=) |
| BR (1) | BR0318269A (https=) |
| CA (2) | CA2523363C (https=) |
| WO (1) | WO2004096183A1 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040170665A1 (en) * | 2000-06-02 | 2004-09-02 | Allergan, Inc. | Intravitreal botulinum toxin implant |
| CA2491312C (en) * | 2002-07-15 | 2011-05-31 | Alcon, Inc. | Bioerodible film for ophthalmic drug delivery |
| US7521481B2 (en) | 2003-02-27 | 2009-04-21 | Mclaurin Joanne | Methods of preventing, treating and diagnosing disorders of protein aggregation |
| US7220422B2 (en) * | 2003-05-20 | 2007-05-22 | Allergan, Inc. | Methods and compositions for treating eye disorders |
| US8673341B2 (en) * | 2004-04-30 | 2014-03-18 | Allergan, Inc. | Intraocular pressure reduction with intracameral bimatoprost implants |
| US7799336B2 (en) | 2004-04-30 | 2010-09-21 | Allergan, Inc. | Hypotensive lipid-containing biodegradable intraocular implants and related methods |
| US9498457B2 (en) | 2004-04-30 | 2016-11-22 | Allergan, Inc. | Hypotensive prostamide-containing biodegradable intraocular implants and related implants |
| US8722097B2 (en) | 2004-04-30 | 2014-05-13 | Allergan, Inc. | Oil-in-water method for making polymeric implants containing a hypotensive lipid |
| US7993634B2 (en) | 2004-04-30 | 2011-08-09 | Allergan, Inc. | Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods |
| US20060073208A1 (en) | 2004-10-01 | 2006-04-06 | Allergan, Inc. | Cosmetic neurotoxin compositions and methods |
| CN103301094A (zh) * | 2004-11-17 | 2013-09-18 | 乔安妮·麦克劳林 | 用于治疗蛋白聚集疾病的含鲨肌醇衍生物的组合物和方法 |
| JP2007051090A (ja) * | 2005-08-18 | 2007-03-01 | Pharma Foods International Co Ltd | 卵白ペプチドを有効成分として含有する血流改善剤 |
| CA2626005A1 (en) * | 2005-10-13 | 2007-10-25 | Waratah Pharmaceuticals Inc. | Inositol derivatives and their uses in the treatment of diseases characterized by abnormal protein folding or aggregation or amyloid formation, deposition, accumulation or persistence |
| US20070197452A1 (en) * | 2006-02-17 | 2007-08-23 | Mclaurin Joanne | Treatment of amyloid-related diseases |
| EP1993523A4 (en) * | 2006-02-17 | 2009-06-10 | Joanne Mclaurin | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PROTEIN AGGREGATION DISORDERS |
| EP1996175A4 (en) * | 2006-03-09 | 2009-06-10 | Waratah Pharmaceuticals Inc | CYCLOHEXAN POLYALKOHOL FORMULATION FOR THE TREATMENT OF PROTEIN AGGREGATION DISORDERS |
| WO2007134449A1 (en) * | 2006-05-19 | 2007-11-29 | Waratah Pharmaceuticals Inc. | Screening methods for amyloid beta modulators |
| WO2007149567A2 (en) | 2006-06-21 | 2007-12-27 | Musc Foundation For Research Development | Targeting complement factor h for treatment of diseases |
| US20100173960A1 (en) * | 2006-09-21 | 2010-07-08 | Antonio Cruz | The Combination of a Cyclohexanehexol and a NSAID for the Treatment of Neurodegenerative Diseases |
| US20100292157A1 (en) * | 2006-11-24 | 2010-11-18 | Antonio Cruz | Combination Treatments for Alzheimer's Disease and Similar Diseases |
| US8969415B2 (en) | 2006-12-01 | 2015-03-03 | Allergan, Inc. | Intraocular drug delivery systems |
| HRP20130768T1 (en) * | 2007-04-12 | 2013-10-25 | Waratah Pharmaceuticals, Inc. | Use of cyclohexanehexol derivatives in the treatment of ocular diseases |
| CA2683546A1 (en) * | 2007-04-12 | 2008-10-23 | Joanne Mclaurin | Use of cyclohexanehexol derivatives in the treatment of .alpha.-synucleinopathies |
| US20110105626A1 (en) * | 2007-04-12 | 2011-05-05 | Mclaurin Joanne | Use of cyclohexanehexol derivatives for the treatment of polyglutamine diseases |
| CA2683580A1 (en) * | 2007-04-12 | 2008-10-23 | Joanne Mclaurin | Treatment of amyotrophic lateral sclerosis |
| US7632848B1 (en) * | 2007-10-04 | 2009-12-15 | Alan Brown Scott | Medical treatment of muscles by exposure to anesthetic drugs |
| US8470337B2 (en) * | 2008-03-13 | 2013-06-25 | Allergan, Inc. | Therapeutic treatments using botulinum neurotoxin |
| EP2334176A4 (en) * | 2008-09-27 | 2012-05-02 | Taraxos Inc | TOPICAL FORMULATIONS FOR THE TREATMENT OF NERVE DISEASES |
| CA2740124A1 (en) * | 2008-10-09 | 2010-04-15 | Waratah Pharmaceuticals Inc. | Use of scyllo-inositols for the treatment of macular degeneration-related disorders |
| US9815890B2 (en) | 2010-06-22 | 2017-11-14 | The Regents Of The University Of Colorado, A Body Corporate | Antibodies to the C3d fragment of complement component 3 |
| KR20130130694A (ko) * | 2010-07-30 | 2013-12-02 | 알러간, 인코포레이티드 | 피부 재생을 위한 화합물과 방법 |
| US20120142684A1 (en) * | 2010-12-02 | 2012-06-07 | Allergan, Inc. | Compounds and methods for skin repair |
| BR112013025826A2 (pt) * | 2011-04-07 | 2016-12-20 | Sensimed Sa | sistema de monitoramento de pelo menos um parâmetro biomecânico oftálmico e método |
| RU2692652C2 (ru) | 2013-03-13 | 2019-06-25 | Джензим Корпорейшн | Слитые белки, содержащие связывающие pdgf и vegf части, и способы их применения |
| RU2535115C1 (ru) | 2013-05-15 | 2014-12-10 | Бости Трейдинг Лтд | Фармацевтический состав, содержащий нейротоксин ботулина |
| US10562946B2 (en) | 2014-06-20 | 2020-02-18 | Genentech, Inc. | Chagasin-based scaffold compositions, methods, and uses |
| JP7097070B2 (ja) | 2015-10-01 | 2022-07-07 | ゴレイニ インコーポレイテッド | クロライドチャネルの標的発現及びその使用方法 |
| US9918994B2 (en) | 2016-03-04 | 2018-03-20 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for muscle regeneration using prostaglandin E2 |
| US11096993B2 (en) | 2016-12-08 | 2021-08-24 | Gary E. Borodic | Method of treating macular degeneration using botulinum toxin-based pharmaceuticals |
| US11123411B2 (en) * | 2016-12-08 | 2021-09-21 | Gary E. Borodic | Method of treating macular degeneration using botulinum toxin-based pharmaceuticals |
| CA3061900A1 (en) * | 2017-05-01 | 2018-11-08 | The Board Of Supervisors Of Louisiana State University And Agriculturaand Mechanical College | Compositions and methods for treating ocular pathologies |
| WO2018227138A1 (en) | 2017-06-09 | 2018-12-13 | The Board Of Trustees Of The Leland Stanford Junior University | Compositions and methods for preventing or treating muscle conditions |
| CN112972444B (zh) * | 2021-02-19 | 2022-07-26 | 中国医学科学院整形外科医院 | 美西律在制备治疗和/或预防面颈部皮肤皱纹的产品中的应用 |
| CN113288784B (zh) * | 2021-06-11 | 2023-03-31 | 中国人民解放军陆军军医大学第一附属医院 | 泪道冲洗收水装置 |
| AU2024297654A1 (en) | 2023-07-13 | 2026-01-22 | Kriya Therapeutics, Inc. | Complement pathway inhibitor fusions and methods of using the same |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3545260A (en) * | 1967-10-31 | 1970-12-08 | Technicon Corp | Means and method for detection of glaucoma |
| US3585849A (en) * | 1968-10-09 | 1971-06-22 | American Optical Corp | Method and apparatus for measuring intraocular pressure |
| US3724263A (en) * | 1970-09-29 | 1973-04-03 | Bio Optronics Inc | Electrical digital display tonometer |
| US3963019A (en) * | 1974-11-25 | 1976-06-15 | Quandt Robert S | Ocular testing method and apparatus |
| US4186184A (en) * | 1977-12-27 | 1980-01-29 | Alza Corporation | Selective administration of drug with ocular therapeutic system |
| US4305399A (en) * | 1978-10-31 | 1981-12-15 | The University Of Western Australia | Miniature transducer |
| CH633952A5 (fr) * | 1980-03-14 | 1983-01-14 | Grounauer Pierre Alain | Dispositif de mesure des potentiels electriques de l'oeil. |
| US4485820A (en) * | 1982-05-10 | 1984-12-04 | The Johns Hopkins University | Method and apparatus for the continuous monitoring of hemoglobin saturation in the blood of premature infants |
| US4734275A (en) * | 1983-08-19 | 1988-03-29 | Research Corporation | Anti-curare agents |
| JPS61321A (ja) * | 1984-06-12 | 1986-01-06 | 株式会社トプコン | 非接触式眼圧計 |
| US4629424A (en) * | 1984-08-30 | 1986-12-16 | Integrated Ionics, Inc. | Intraoral ambient sensing device |
| US4771792A (en) * | 1985-02-19 | 1988-09-20 | Seale Joseph B | Non-invasive determination of mechanical characteristics in the body |
| US4628938A (en) * | 1985-12-09 | 1986-12-16 | Lee David A | Continuous applanation tonometer |
| DE3785602T2 (de) * | 1986-03-13 | 1993-09-02 | Univ Columbia | Verwendung von a-, b- und c-prostaglandinen und deren derivaten zur behandlung von augen-hypertension und glaukom. |
| JPS63267331A (ja) * | 1986-12-27 | 1988-11-04 | Tokyo Optical Co Ltd | 非接触式眼圧計 |
| US5076274A (en) * | 1987-02-18 | 1991-12-31 | Canon Kabushiki Kaisha | Non-contact tonometer |
| US5183044A (en) * | 1987-06-30 | 1993-02-02 | Kabushiki Kaisha Topcon | Noncontact type tonometer |
| US4922913A (en) * | 1987-11-12 | 1990-05-08 | Waters Jr George E | Intraocular pressure sensor |
| US4860755A (en) * | 1988-02-08 | 1989-08-29 | Erath-Young Instrument Company, Inc. | Differential pressure applanation tonometer |
| US5165409A (en) * | 1988-08-23 | 1992-11-24 | Coan William M | Tonometry apparatus |
| US4951671A (en) * | 1988-08-23 | 1990-08-28 | Coan William M | Tonometry apparatus |
| US5005577A (en) * | 1988-08-23 | 1991-04-09 | Frenkel Ronald E P | Intraocular lens pressure monitoring device |
| US5217015A (en) * | 1990-06-08 | 1993-06-08 | Kaye David B | Pressure sensing device having transducer overlying and deforming eye |
| US5109852A (en) * | 1990-06-08 | 1992-05-05 | Kaye David B | Method for sensing pressure in an object |
| US5342283A (en) * | 1990-08-13 | 1994-08-30 | Good Roger R | Endocurietherapy |
| US5148807A (en) * | 1990-08-28 | 1992-09-22 | Ohio State University | Non-contact tonometer |
| US5209231A (en) * | 1990-11-02 | 1993-05-11 | University Of Connecticut | Optical glucose sensor apparatus and method |
| US5295495A (en) * | 1991-05-13 | 1994-03-22 | The Australian National University | Glaucoma testing from observations of optokinetic nystagmus |
| US5251627A (en) * | 1991-06-27 | 1993-10-12 | Morris Donald E | Non-invasive measurement of eyeball pressure using vibration |
| US5179953A (en) * | 1991-08-27 | 1993-01-19 | Jermik Systems, Ltd. | Portable diurnal intraocular pressure recording system |
| US5972991A (en) * | 1992-09-21 | 1999-10-26 | Allergan | Cyclopentane heptan(ene) oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| US5375595A (en) * | 1993-03-17 | 1994-12-27 | The Regents Of The University Of Calif. | Apparatus and method for non-contact, acoustic resonance determination of intraocular pressure |
| US6350781B1 (en) * | 1994-01-14 | 2002-02-26 | Lee Shahinia, Jr. | Method and analgesic preparations for sustained and extended corneal analgesia with subanesthetic concentrations of lidocaine |
| DK0866691T4 (da) * | 1995-11-06 | 2005-06-06 | Somerset Pharmaceuticals Inc | Medikamenter til sublingual og bukkal administration af selegilin |
| US5830139A (en) * | 1996-09-04 | 1998-11-03 | Abreu; Marcio M. | Tonometer system for measuring intraocular pressure by applanation and/or indentation |
| US6120460A (en) * | 1996-09-04 | 2000-09-19 | Abreu; Marcio Marc | Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions |
| US6544193B2 (en) * | 1996-09-04 | 2003-04-08 | Marcio Marc Abreu | Noninvasive measurement of chemical substances |
| US5922746A (en) * | 1997-03-27 | 1999-07-13 | Allergan | Inhibition of noninactivating Na channels of mammalian optic nerve as a means of preventing optic nerve degeneration associated with glaucoma |
| US6090847A (en) * | 1997-11-21 | 2000-07-18 | Allergan Sales, Inc. | EP2 -receptor agonists as neuroprotective agents for the eye |
| US6294583B1 (en) * | 1998-01-13 | 2001-09-25 | Synchroneuron, Llc | Methods of treating tardive dyskinesia and other movement disorders |
| WO2000004898A1 (en) * | 1998-07-21 | 2000-02-03 | Merck & Co., Inc. | Ophthalmic compositions for treating ocular hypertension |
| AU2211700A (en) * | 1998-12-24 | 2000-07-31 | Alcon Laboratories, Inc. | Prostaglandin e agonists for treatment of glaucoma |
| WO2001042191A1 (en) * | 1999-12-08 | 2001-06-14 | Warner-Lambert Company | Branched chain amino acid-dependent aminotransferase inhibitors and their use in the treatment of diabetic retinopathy |
| US6306403B1 (en) * | 2000-06-14 | 2001-10-23 | Allergan Sales, Inc. | Method for treating parkinson's disease with a botulinum toxin |
-
2003
- 2003-04-24 US US10/421,956 patent/US20040058313A1/en not_active Abandoned
- 2003-12-08 JP JP2004571477A patent/JP2006524185A/ja active Pending
- 2003-12-08 EP EP03816832.4A patent/EP1622589B1/en not_active Expired - Lifetime
- 2003-12-08 CA CA2523363A patent/CA2523363C/en not_active Expired - Fee Related
- 2003-12-08 AU AU2003297684A patent/AU2003297684A1/en not_active Abandoned
- 2003-12-08 BR BRPI0318269-0A patent/BR0318269A/pt not_active Application Discontinuation
- 2003-12-08 CA CA2868648A patent/CA2868648A1/en not_active Abandoned
- 2003-12-08 WO PCT/US2003/038740 patent/WO2004096183A1/en not_active Ceased
-
2012
- 2012-07-20 US US13/554,349 patent/US20120282242A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2868648A1 (en) | 2004-11-11 |
| US20120282242A1 (en) | 2012-11-08 |
| EP1622589A4 (en) | 2009-07-15 |
| CA2523363C (en) | 2015-02-10 |
| EP1622589B1 (en) | 2017-03-15 |
| JP2006524185A (ja) | 2006-10-26 |
| AU2003297684A1 (en) | 2004-11-23 |
| WO2004096183A1 (en) | 2004-11-11 |
| CA2523363A1 (en) | 2004-11-11 |
| US20040058313A1 (en) | 2004-03-25 |
| EP1622589A1 (en) | 2006-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
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