CA2523363C - Compositions, targets, methods and devices for the therapy of ocular and periocular disorders - Google Patents

Compositions, targets, methods and devices for the therapy of ocular and periocular disorders Download PDF

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Publication number
CA2523363C
CA2523363C CA2523363A CA2523363A CA2523363C CA 2523363 C CA2523363 C CA 2523363C CA 2523363 A CA2523363 A CA 2523363A CA 2523363 A CA2523363 A CA 2523363A CA 2523363 C CA2523363 C CA 2523363C
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CA
Canada
Prior art keywords
eye
pressure
muscle
eyelid
botulinum toxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2523363A
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English (en)
French (fr)
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CA2523363A1 (en
Inventor
Marcio Marc Abreu
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Individual
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Individual
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Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA2868648A priority Critical patent/CA2868648A1/en
Publication of CA2523363A1 publication Critical patent/CA2523363A1/en
Application granted granted Critical
Publication of CA2523363C publication Critical patent/CA2523363C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886Metalloendopeptidases (3.4.24), e.g. collagenase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
CA2523363A 2003-04-24 2003-12-08 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders Expired - Fee Related CA2523363C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2868648A CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/421,956 US20040058313A1 (en) 2002-04-24 2003-04-24 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
US10/421,956 2003-04-24
PCT/US2003/038740 WO2004096183A1 (en) 2003-04-24 2003-12-08 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2868648A Division CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Publications (2)

Publication Number Publication Date
CA2523363A1 CA2523363A1 (en) 2004-11-11
CA2523363C true CA2523363C (en) 2015-02-10

Family

ID=33415845

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2523363A Expired - Fee Related CA2523363C (en) 2003-04-24 2003-12-08 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
CA2868648A Abandoned CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2868648A Abandoned CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Country Status (7)

Country Link
US (2) US20040058313A1 (https=)
EP (1) EP1622589B1 (https=)
JP (1) JP2006524185A (https=)
AU (1) AU2003297684A1 (https=)
BR (1) BR0318269A (https=)
CA (2) CA2523363C (https=)
WO (1) WO2004096183A1 (https=)

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US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US20060073208A1 (en) 2004-10-01 2006-04-06 Allergan, Inc. Cosmetic neurotoxin compositions and methods
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US20070197452A1 (en) * 2006-02-17 2007-08-23 Mclaurin Joanne Treatment of amyloid-related diseases
US20070197453A1 (en) * 2006-02-17 2007-08-23 Mclaurin Joanne Compositions and methods for treatment of disorders of protein aggregation
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US20120142684A1 (en) * 2010-12-02 2012-06-07 Allergan, Inc. Compounds and methods for skin repair
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CN105188733B (zh) 2013-03-13 2020-05-08 建新公司 包含pdgf和vegf结合部分的融合蛋白及其使用方法
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JP6655074B2 (ja) 2014-06-20 2020-02-26 ジェネンテック, インコーポレイテッド シャガシンに基づく足場組成物、方法及び使用
JP7097070B2 (ja) 2015-10-01 2022-07-07 ゴレイニ インコーポレイテッド クロライドチャネルの標的発現及びその使用方法
US9918994B2 (en) 2016-03-04 2018-03-20 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for muscle regeneration using prostaglandin E2
US11096993B2 (en) 2016-12-08 2021-08-24 Gary E. Borodic Method of treating macular degeneration using botulinum toxin-based pharmaceuticals
US11123411B2 (en) * 2016-12-08 2021-09-21 Gary E. Borodic Method of treating macular degeneration using botulinum toxin-based pharmaceuticals
AU2018263853A1 (en) * 2017-05-01 2019-11-14 The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Compositions and methods for treating ocular pathologies
WO2018227138A1 (en) 2017-06-09 2018-12-13 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for preventing or treating muscle conditions
CN112972444B (zh) * 2021-02-19 2022-07-26 中国医学科学院整形外科医院 美西律在制备治疗和/或预防面颈部皮肤皱纹的产品中的应用
CN113288784B (zh) * 2021-06-11 2023-03-31 中国人民解放军陆军军医大学第一附属医院 泪道冲洗收水装置
KR20260039752A (ko) 2023-07-13 2026-03-20 크리야 테라퓨틱스, 인크. 보체 경로 억제제 융합체 및 그의 사용 방법

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Also Published As

Publication number Publication date
EP1622589B1 (en) 2017-03-15
WO2004096183A1 (en) 2004-11-11
EP1622589A1 (en) 2006-02-08
AU2003297684A1 (en) 2004-11-23
US20040058313A1 (en) 2004-03-25
CA2523363A1 (en) 2004-11-11
BR0318269A (pt) 2006-05-23
US20120282242A1 (en) 2012-11-08
JP2006524185A (ja) 2006-10-26
CA2868648A1 (en) 2004-11-11
EP1622589A4 (en) 2009-07-15

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