CA2523363C - Compositions, targets, methods and devices for the therapy of ocular and periocular disorders - Google Patents

Compositions, targets, methods and devices for the therapy of ocular and periocular disorders Download PDF

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Publication number
CA2523363C
CA2523363C CA2523363A CA2523363A CA2523363C CA 2523363 C CA2523363 C CA 2523363C CA 2523363 A CA2523363 A CA 2523363A CA 2523363 A CA2523363 A CA 2523363A CA 2523363 C CA2523363 C CA 2523363C
Authority
CA
Canada
Prior art keywords
eye
pressure
muscle
eyelid
botulinum toxin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2523363A
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English (en)
French (fr)
Other versions
CA2523363A1 (en
Inventor
Marcio Marc Abreu
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Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CA2868648A priority Critical patent/CA2868648A1/en
Publication of CA2523363A1 publication Critical patent/CA2523363A1/en
Application granted granted Critical
Publication of CA2523363C publication Critical patent/CA2523363C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
CA2523363A 2003-04-24 2003-12-08 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders Expired - Fee Related CA2523363C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2868648A CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/421,956 2003-04-24
US10/421,956 US20040058313A1 (en) 2002-04-24 2003-04-24 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
PCT/US2003/038740 WO2004096183A1 (en) 2003-04-24 2003-12-08 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA2868648A Division CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Publications (2)

Publication Number Publication Date
CA2523363A1 CA2523363A1 (en) 2004-11-11
CA2523363C true CA2523363C (en) 2015-02-10

Family

ID=33415845

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2523363A Expired - Fee Related CA2523363C (en) 2003-04-24 2003-12-08 Compositions, targets, methods and devices for the therapy of ocular and periocular disorders
CA2868648A Abandoned CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2868648A Abandoned CA2868648A1 (en) 2003-04-24 2003-12-08 Compounds for enhancing blood flow to the retina and optic nerve

Country Status (7)

Country Link
US (2) US20040058313A1 (https=)
EP (1) EP1622589B1 (https=)
JP (1) JP2006524185A (https=)
AU (1) AU2003297684A1 (https=)
BR (1) BR0318269A (https=)
CA (2) CA2523363C (https=)
WO (1) WO2004096183A1 (https=)

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US7220422B2 (en) * 2003-05-20 2007-05-22 Allergan, Inc. Methods and compositions for treating eye disorders
US8673341B2 (en) * 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US20060073208A1 (en) 2004-10-01 2006-04-06 Allergan, Inc. Cosmetic neurotoxin compositions and methods
CN103301094A (zh) * 2004-11-17 2013-09-18 乔安妮·麦克劳林 用于治疗蛋白聚集疾病的含鲨肌醇衍生物的组合物和方法
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US20070197452A1 (en) * 2006-02-17 2007-08-23 Mclaurin Joanne Treatment of amyloid-related diseases
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US9815890B2 (en) 2010-06-22 2017-11-14 The Regents Of The University Of Colorado, A Body Corporate Antibodies to the C3d fragment of complement component 3
KR20130130694A (ko) * 2010-07-30 2013-12-02 알러간, 인코포레이티드 피부 재생을 위한 화합물과 방법
US20120142684A1 (en) * 2010-12-02 2012-06-07 Allergan, Inc. Compounds and methods for skin repair
BR112013025826A2 (pt) * 2011-04-07 2016-12-20 Sensimed Sa sistema de monitoramento de pelo menos um parâmetro biomecânico oftálmico e método
RU2692652C2 (ru) 2013-03-13 2019-06-25 Джензим Корпорейшн Слитые белки, содержащие связывающие pdgf и vegf части, и способы их применения
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US10562946B2 (en) 2014-06-20 2020-02-18 Genentech, Inc. Chagasin-based scaffold compositions, methods, and uses
JP7097070B2 (ja) 2015-10-01 2022-07-07 ゴレイニ インコーポレイテッド クロライドチャネルの標的発現及びその使用方法
US9918994B2 (en) 2016-03-04 2018-03-20 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for muscle regeneration using prostaglandin E2
US11096993B2 (en) 2016-12-08 2021-08-24 Gary E. Borodic Method of treating macular degeneration using botulinum toxin-based pharmaceuticals
US11123411B2 (en) * 2016-12-08 2021-09-21 Gary E. Borodic Method of treating macular degeneration using botulinum toxin-based pharmaceuticals
CA3061900A1 (en) * 2017-05-01 2018-11-08 The Board Of Supervisors Of Louisiana State University And Agriculturaand Mechanical College Compositions and methods for treating ocular pathologies
WO2018227138A1 (en) 2017-06-09 2018-12-13 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for preventing or treating muscle conditions
CN112972444B (zh) * 2021-02-19 2022-07-26 中国医学科学院整形外科医院 美西律在制备治疗和/或预防面颈部皮肤皱纹的产品中的应用
CN113288784B (zh) * 2021-06-11 2023-03-31 中国人民解放军陆军军医大学第一附属医院 泪道冲洗收水装置
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Also Published As

Publication number Publication date
CA2868648A1 (en) 2004-11-11
US20120282242A1 (en) 2012-11-08
EP1622589A4 (en) 2009-07-15
EP1622589B1 (en) 2017-03-15
BR0318269A (pt) 2006-05-23
JP2006524185A (ja) 2006-10-26
AU2003297684A1 (en) 2004-11-23
WO2004096183A1 (en) 2004-11-11
CA2523363A1 (en) 2004-11-11
US20040058313A1 (en) 2004-03-25
EP1622589A1 (en) 2006-02-08

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