BR0317795A - Derivados de alfa-aminoamida úteis como agentes antienxaqueca - Google Patents

Derivados de alfa-aminoamida úteis como agentes antienxaqueca

Info

Publication number
BR0317795A
BR0317795A BR0317795-5A BR0317795A BR0317795A BR 0317795 A BR0317795 A BR 0317795A BR 0317795 A BR0317795 A BR 0317795A BR 0317795 A BR0317795 A BR 0317795A
Authority
BR
Brazil
Prior art keywords
alpha
derivatives useful
aminoamide derivatives
migraine agents
migraine
Prior art date
Application number
BR0317795-5A
Other languages
English (en)
Other versions
BRPI0317795B8 (pt
BRPI0317795B1 (pt
Inventor
Patricia Salvati
Marcello Calabresi
Luciano Dho
Orietta Veneroni
Piero Melloni
Original Assignee
Newron Pharm Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Newron Pharm Spa filed Critical Newron Pharm Spa
Publication of BR0317795A publication Critical patent/BR0317795A/pt
Publication of BRPI0317795B1 publication Critical patent/BRPI0317795B1/pt
Publication of BRPI0317795B8 publication Critical patent/BRPI0317795B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

"DERIVADOS DE ALFA-AMINOAMIDA úTEIS COMO AGENTES ANTIENXAQUECA". A invenção se refere aos derivados <244>-aminoamidas úteis como agentes antienxaqueca, particularmente para o tratamento de enxaquecas, cefaléias em salvas ou outra cefaléia grave. Os agentes antienxaqueca de acordo com a invenção podem reduzir ou mesmo parar as dores provenientes de situações das dores mencionadas sem, praticamente, qualquer efeito colateral.
BRPI0317795A 2003-01-16 2003-11-18 derivados de alfa-aminoamida úteis como agentes antienxaqueca BRPI0317795B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP03000921A EP1438956A1 (en) 2003-01-16 2003-01-16 Alpha-aminoamide derivatives useful as antimigraine agents
EP03000921.1 2003-01-16
PCT/EP2003/012889 WO2004062655A1 (en) 2003-01-16 2003-11-18 Alpha-aminoamide derivatives useful as antimigraine agents

Publications (3)

Publication Number Publication Date
BR0317795A true BR0317795A (pt) 2005-11-22
BRPI0317795B1 BRPI0317795B1 (pt) 2019-04-02
BRPI0317795B8 BRPI0317795B8 (pt) 2021-05-25

Family

ID=32524140

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0317795A BRPI0317795B8 (pt) 2003-01-16 2003-11-18 derivados de alfa-aminoamida úteis como agentes antienxaqueca

Country Status (21)

Country Link
US (2) US7709523B2 (pt)
EP (2) EP1438956A1 (pt)
JP (1) JP4885455B2 (pt)
KR (1) KR101049694B1 (pt)
CN (1) CN100418517C (pt)
AT (1) ATE380026T1 (pt)
AU (1) AU2003279399B8 (pt)
BR (1) BRPI0317795B8 (pt)
CA (1) CA2510514C (pt)
CY (1) CY1107274T1 (pt)
DE (1) DE60317935T2 (pt)
DK (1) DK1585510T3 (pt)
ES (1) ES2295658T3 (pt)
HK (1) HK1086487A1 (pt)
MX (1) MXPA05007339A (pt)
NO (1) NO333610B1 (pt)
NZ (1) NZ541117A (pt)
PT (1) PT1585510E (pt)
RU (1) RU2336077C2 (pt)
SI (1) SI1585510T1 (pt)
WO (1) WO2004062655A1 (pt)

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GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AU2002333374B2 (en) 2001-09-03 2007-03-22 Newron Pharmaceuticals S.P.A. Pharmaceutical composition comprising gabapentin or an analogue thereof and an (alpha)- aminoamide and its analgesic use
EP1658062B1 (en) * 2003-08-25 2010-02-17 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as anti-inflammatory agents
SI1809271T1 (sl) * 2004-09-10 2010-10-29 Newron Pharm Spa Uporaba (R)-(halobenziloksi) benzilamino propanamidov kot selektivnih modulatorjev natrijevih in/ali kalcijevih kanalov
RS54522B1 (en) 2005-12-22 2016-06-30 Newron Pharmaceuticals S.P.A. 2-Phenylethylamino Derivatives as Modulators of Calcium and (or Sodium) Channels
RS53824B1 (en) * 2006-06-19 2015-06-30 Newron Pharmaceuticals S.P.A. PROCESS FOR OBTAINING 2- [4- (3-AND 2-FLUOROBENZYLOXY) BENZYLAMINO] PROPANAMIDE
FR2903985B1 (fr) 2006-07-24 2008-09-05 Sanofi Aventis Sa Derives de n-(amino-heteroaryl)-1h-indole-2-carboxamides, leur preparation et leur application en therapeutique
CN101687773B (zh) 2007-06-15 2014-07-30 纽朗制药有限公司 取代的2-[2-(苯基)乙氨基]烷酰胺衍生物及其作为钠和/或钙通道调节剂的应用
DK2229351T3 (en) * 2007-12-11 2018-01-22 Newron Pharm Spa PROCEDURE FOR THE PREPARATION OF 2- [4- (3- OR 2-FLUORBENZYLOXY) BENZYLAMINO] PROPANAMIDS WITH HIGH PURITY
EP2314569A1 (en) 2009-10-22 2011-04-27 Merck Patent GmbH Novel polymorphic forms of (S)-2-[4-(3-Fluoro-benzyloxy)-benzylamino]-propionamide mesylate salt and processes of manufacturing thereof
LT2563355T (lt) * 2010-04-27 2016-09-26 Newron Pharmaceuticals S.P.A. Ralfinamido metansulfonato druskų arba jų r-enentiomerų gavimo būdas
WO2015102390A1 (ko) * 2013-12-30 2015-07-09 이화여자대학교 산학협력단 신규한 아미드 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 포함하는 통증의 예방 또는 치료용 약학적 조성물
CN107522654B (zh) * 2016-06-21 2020-09-01 中国人民解放军军事医学科学院毒物药物研究所 新的α-氨基酰胺衍生物及其医药用途
WO2019205147A1 (zh) * 2018-04-28 2019-10-31 上海璃道医药科技有限公司 包含苯并含氧脂肪环结构的氨基乙酰胺类化合物及其用途
CN112716927B (zh) * 2020-10-12 2022-10-14 复旦大学 α-氨基酰胺类化合物及其制备方法与应用

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Also Published As

Publication number Publication date
US7709523B2 (en) 2010-05-04
CA2510514A1 (en) 2004-07-29
AU2003279399A1 (en) 2004-08-10
NO333610B1 (no) 2013-07-22
US20060079570A1 (en) 2006-04-13
SI1585510T1 (sl) 2008-04-30
EP1438956A1 (en) 2004-07-21
NO20053780D0 (no) 2005-08-09
NO20053780L (no) 2005-10-13
JP2006514060A (ja) 2006-04-27
KR20050094852A (ko) 2005-09-28
ATE380026T1 (de) 2007-12-15
MXPA05007339A (es) 2005-09-30
AU2003279399B2 (en) 2008-11-27
ES2295658T3 (es) 2008-04-16
BRPI0317795B8 (pt) 2021-05-25
US20100267835A1 (en) 2010-10-21
CY1107274T1 (el) 2012-11-21
EP1585510A1 (en) 2005-10-19
JP4885455B2 (ja) 2012-02-29
WO2004062655A1 (en) 2004-07-29
DE60317935T2 (de) 2008-11-27
RU2336077C2 (ru) 2008-10-20
EP1585510B1 (en) 2007-12-05
DE60317935D1 (de) 2008-01-17
RU2005125919A (ru) 2006-01-10
CN1738611A (zh) 2006-02-22
NZ541117A (en) 2008-02-29
CA2510514C (en) 2011-07-26
KR101049694B1 (ko) 2011-07-19
HK1086487A1 (en) 2006-09-22
AU2003279399B8 (en) 2009-01-29
PT1585510E (pt) 2008-02-28
DK1585510T3 (da) 2008-02-25
CN100418517C (zh) 2008-09-17
BRPI0317795B1 (pt) 2019-04-02

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Legal Events

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

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B12B Appeal against refusal [chapter 12.2 patent gazette]
B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
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