BR0316478A - Estabilização de materiais poliméricos contendo poli(oxialquileno) - Google Patents

Estabilização de materiais poliméricos contendo poli(oxialquileno)

Info

Publication number
BR0316478A
BR0316478A BR0316478-0A BR0316478A BR0316478A BR 0316478 A BR0316478 A BR 0316478A BR 0316478 A BR0316478 A BR 0316478A BR 0316478 A BR0316478 A BR 0316478A
Authority
BR
Brazil
Prior art keywords
oxyalkylene
poly
medical device
stabilization
polymeric materials
Prior art date
Application number
BR0316478-0A
Other languages
English (en)
Inventor
Brian Gerrard Devlin
Arturo Borberto Medina
Karen Belinda Sentell
Stephen Raymond Perreault
Mireille Tena
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR0316478A publication Critical patent/BR0316478A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L75/00—Compositions of polyureas or polyurethanes; Compositions of derivatives of such polymers
    • C08L75/04—Polyurethanes
    • C08L75/14—Polyurethanes having carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/18—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/40—High-molecular-weight compounds
    • C08G18/48—Polyethers
    • C08G18/50—Polyethers having heteroatoms other than oxygen
    • C08G18/5021—Polyethers having heteroatoms other than oxygen having nitrogen
    • C08G18/5024—Polyethers having heteroatoms other than oxygen having nitrogen containing primary and/or secondary amino groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/65—Low-molecular-weight compounds having active hydrogen with high-molecular-weight compounds having active hydrogen
    • C08G18/66—Compounds of groups C08G18/42, C08G18/48, or C08G18/52
    • C08G18/6666—Compounds of group C08G18/48 or C08G18/52
    • C08G18/667—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38
    • C08G18/6681—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/32 or C08G18/3271 and/or polyamines of C08G18/38
    • C08G18/6685—Compounds of group C08G18/48 or C08G18/52 with compounds of group C08G18/32 or polyamines of C08G18/38 with compounds of group C08G18/32 or C08G18/3271 and/or polyamines of C08G18/38 with compounds of group C08G18/3225 or polyamines of C08G18/38
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/71—Monoisocyanates or monoisothiocyanates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/09—Carboxylic acids; Metal salts thereof; Anhydrides thereof
    • C08K5/098—Metal salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G2120/00—Compositions for reaction injection moulding processes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/32—Phosphorus-containing compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/09—Carboxylic acids; Metal salts thereof; Anhydrides thereof
    • C08K5/092—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/16—Nitrogen-containing compounds
    • C08K5/17—Amines; Quaternary ammonium compounds
    • C08K5/175—Amines; Quaternary ammonium compounds containing COOH-groups; Esters or salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00—Applications
    • C08L2203/02—Applications for biomedical use

Abstract

"ESTABILIZAçAO DE MATERIAIS POLIMéRICOS CONTENDO POLI(OXIALQUILENO)". A presente invenção provê um processo para produção de um dispositivo médico, preferivelmente um dispositivo oftálmico, mais preferivelmente uma lente de contato, fabricada de um material polimérico contendo poli(oxialquileno) estabilidado. O processo da invenção compreende as etapas de: cura, em um molde, de uma composição compreendendo (a) um pré-polímero tendo pelo menos uma unidade poli(oxialquileno), (b) um multi-ácido orgânico biocompatível ou seu sal biocompatível em uma quantidade suficiente para aperfeiçoar a estabilidade do polímero contendo poli(oxialquileno) fabricado a partir da composição, (c) opcionalmente um fotoiniciador ou um iniciador térmico, e (d) opcionalmente um ou mais monómeros vinílicos, para formar o dispositivo médico sendo menos suscetível a degradação; e removendo o dispositivo médico do molde.
BR0316478-0A 2002-11-27 2003-11-26 Estabilização de materiais poliméricos contendo poli(oxialquileno) BR0316478A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US42971902P 2002-11-27 2002-11-27
US51259103P 2003-10-17 2003-10-17
PCT/EP2003/013320 WO2004048472A2 (en) 2002-11-27 2003-11-26 Stabilization of poly(oxyalkylene) contining polymeric materials

Publications (1)

Publication Number Publication Date
BR0316478A true BR0316478A (pt) 2005-10-11

Family

ID=32397213

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0316478-0A BR0316478A (pt) 2002-11-27 2003-11-26 Estabilização de materiais poliméricos contendo poli(oxialquileno)

Country Status (11)

Country Link
US (2) US20040116564A1 (pt)
EP (1) EP1567585B1 (pt)
JP (1) JP4681882B2 (pt)
AT (1) ATE399570T1 (pt)
AU (1) AU2003288178B2 (pt)
BR (1) BR0316478A (pt)
CA (1) CA2503529C (pt)
DE (1) DE60321955D1 (pt)
MX (1) MXPA05005626A (pt)
NO (1) NO20052917L (pt)
WO (1) WO2004048472A2 (pt)

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Also Published As

Publication number Publication date
EP1567585A2 (en) 2005-08-31
JP4681882B2 (ja) 2011-05-11
AU2003288178B2 (en) 2006-11-30
US8318059B2 (en) 2012-11-27
CA2503529A1 (en) 2004-06-10
WO2004048472A3 (en) 2004-07-15
CA2503529C (en) 2011-03-01
US20090263278A1 (en) 2009-10-22
EP1567585B1 (en) 2008-07-02
DE60321955D1 (de) 2008-08-14
WO2004048472A2 (en) 2004-06-10
AU2003288178A1 (en) 2004-06-18
ATE399570T1 (de) 2008-07-15
JP2006508716A (ja) 2006-03-16
US20040116564A1 (en) 2004-06-17
MXPA05005626A (es) 2005-07-27
NO20052917L (no) 2005-06-15

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