BR0314269A - Cápsulas contendo composições aquosas de recheio estabilizadas com ciclodextrina derivatizada - Google Patents

Cápsulas contendo composições aquosas de recheio estabilizadas com ciclodextrina derivatizada

Info

Publication number
BR0314269A
BR0314269A BR0314269-8A BR0314269A BR0314269A BR 0314269 A BR0314269 A BR 0314269A BR 0314269 A BR0314269 A BR 0314269A BR 0314269 A BR0314269 A BR 0314269A
Authority
BR
Brazil
Prior art keywords
derivatized cyclodextrin
cyclodextrin
water
filler composition
shell
Prior art date
Application number
BR0314269-8A
Other languages
English (en)
Inventor
Diane O Thompson
Rupert O Zimmerer
James D Pipkin
Original Assignee
Cydex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cydex Inc filed Critical Cydex Inc
Publication of BR0314269A publication Critical patent/BR0314269A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A61K31/724—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891—Coated capsules; Multilayered drug free capsule shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"CáPSULAS CONTENDO COMPOSIçõES AQUOSAS DE RECHEIO ESTABILIZADAS COM CICLODEXTRINA DERIVATIZADA". Uma cápsula que contém uma composição aquosa de enchimento que compreende água, uma ciclodextrina derivatizada, tal como sulfoalquil éter ciclodextrina (SAE-CD) ou hidroxipropil ciclodextrina (HPCD), opcionalmente um ou mais agentes ativos e opcionalmente um ou mais excipientes é estabilizada contra degradação, erosão, inchação ou dissolução de sua casca durante armazenagem. A ciclodextrina derivatizada está presente em uma quantidade suficiente para reduzir, eliminar ou inibir degradação, erosão, inchação ou dissolução da casca pela água presente na composição de enchimento. Alternativamente, a ciclodextrina derivatizada e um outro material estabilizador de casca juntos estabilizam a casca contra degradação, erosão, inchação e/ou dissolução pela água presente na composição de enchimento. A ciclodextrina derivatizada pode reduzir a atividade em água da composição de enchimento.
BR0314269-8A 2002-09-13 2003-09-12 Cápsulas contendo composições aquosas de recheio estabilizadas com ciclodextrina derivatizada BR0314269A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41085002P 2002-09-13 2002-09-13
PCT/US2003/030960 WO2004024126A1 (en) 2002-09-13 2003-09-12 Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin

Publications (1)

Publication Number Publication Date
BR0314269A true BR0314269A (pt) 2005-07-26

Family

ID=31994217

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314269-8A BR0314269A (pt) 2002-09-13 2003-09-12 Cápsulas contendo composições aquosas de recheio estabilizadas com ciclodextrina derivatizada

Country Status (11)

Country Link
US (1) US7829114B2 (pt)
EP (1) EP1545477A4 (pt)
JP (1) JP2006503047A (pt)
KR (1) KR20050046776A (pt)
CN (1) CN100344328C (pt)
AU (1) AU2003275329B2 (pt)
BR (1) BR0314269A (pt)
CA (1) CA2498410A1 (pt)
MX (1) MXPA05002728A (pt)
RU (1) RU2359698C2 (pt)
WO (1) WO2004024126A1 (pt)

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Also Published As

Publication number Publication date
WO2004024126B1 (en) 2004-07-22
KR20050046776A (ko) 2005-05-18
EP1545477A1 (en) 2005-06-29
RU2005110945A (ru) 2005-10-27
WO2004024126A1 (en) 2004-03-25
EP1545477A4 (en) 2006-11-22
AU2003275329B2 (en) 2008-04-03
CN1694688A (zh) 2005-11-09
CN100344328C (zh) 2007-10-24
US20050186267A1 (en) 2005-08-25
JP2006503047A (ja) 2006-01-26
US7829114B2 (en) 2010-11-09
MXPA05002728A (es) 2005-07-25
AU2003275329A1 (en) 2004-04-30
CA2498410A1 (en) 2004-03-25
RU2359698C2 (ru) 2009-06-27

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI. A61K 9/48, A61K 9/52, A61P 25/24, A61P 29/00, A61P 37/08, A61P 9/02

Ipc: A61K 9/48 (2011.01), A61K 9/52 (2011.01), A61P 25/

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012.