IT201700015145A1 - Capsule di gelatina molle ad elevata stabilità - Google Patents

Capsule di gelatina molle ad elevata stabilità

Info

Publication number
IT201700015145A1
IT201700015145A1 IT102017000015145A IT201700015145A IT201700015145A1 IT 201700015145 A1 IT201700015145 A1 IT 201700015145A1 IT 102017000015145 A IT102017000015145 A IT 102017000015145A IT 201700015145 A IT201700015145 A IT 201700015145A IT 201700015145 A1 IT201700015145 A1 IT 201700015145A1
Authority
IT
Italy
Prior art keywords
gelatin capsules
high stability
soft gelatin
stability soft
capsules
Prior art date
Application number
IT102017000015145A
Other languages
English (en)
Inventor
Simone Carucci
Maurizio Marchiorri
Marco Pontiggia
Tiziano Fossati
Original Assignee
Altergon Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altergon Sa filed Critical Altergon Sa
Priority to IT102017000015145A priority Critical patent/IT201700015145A1/it
Priority to US16/479,262 priority patent/US11090271B2/en
Priority to CA3050347A priority patent/CA3050347C/en
Priority to EP18707636.9A priority patent/EP3579880B1/en
Priority to DK18707636.9T priority patent/DK3579880T3/da
Priority to RU2019120281A priority patent/RU2768630C2/ru
Priority to CN201880006414.1A priority patent/CN110214030B/zh
Priority to PCT/EP2018/053244 priority patent/WO2018146237A1/en
Publication of IT201700015145A1 publication Critical patent/IT201700015145A1/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT102017000015145A 2017-02-10 2017-02-10 Capsule di gelatina molle ad elevata stabilità IT201700015145A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT102017000015145A IT201700015145A1 (it) 2017-02-10 2017-02-10 Capsule di gelatina molle ad elevata stabilità
US16/479,262 US11090271B2 (en) 2017-02-10 2018-02-09 Soft gelatin capsules containing hydroxypropyl beta cyclodextrin with high stability
CA3050347A CA3050347C (en) 2017-02-10 2018-02-09 Soft gelatin capsules containing h yd roxyp ro pyl beta cyclodextrin with high stability
EP18707636.9A EP3579880B1 (en) 2017-02-10 2018-02-09 Soft gelatin capsules containing hydroxypropyl beta cyclodextrin with high stability
DK18707636.9T DK3579880T3 (en) 2017-02-10 2018-02-09 Soft gelatin capsules containing hydroxypropyl beta cyclodextrin with high stability
RU2019120281A RU2768630C2 (ru) 2017-02-10 2018-02-09 Мягкие желатиновые капсулы с высокой стабильностью, содержащие гидроксипропил-бета-циклодекстрин
CN201880006414.1A CN110214030B (zh) 2017-02-10 2018-02-09 具有高稳定性的含有羟丙基β环糊精的软明胶胶囊
PCT/EP2018/053244 WO2018146237A1 (en) 2017-02-10 2018-02-09 Soft gelatin capsules containing h yd roxyp ro pyl beta cyclodextrin with high stability

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102017000015145A IT201700015145A1 (it) 2017-02-10 2017-02-10 Capsule di gelatina molle ad elevata stabilità

Publications (1)

Publication Number Publication Date
IT201700015145A1 true IT201700015145A1 (it) 2018-08-10

Family

ID=59067800

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102017000015145A IT201700015145A1 (it) 2017-02-10 2017-02-10 Capsule di gelatina molle ad elevata stabilità

Country Status (8)

Country Link
US (1) US11090271B2 (it)
EP (1) EP3579880B1 (it)
CN (1) CN110214030B (it)
CA (1) CA3050347C (it)
DK (1) DK3579880T3 (it)
IT (1) IT201700015145A1 (it)
RU (1) RU2768630C2 (it)
WO (1) WO2018146237A1 (it)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024126A1 (en) * 2002-09-13 2004-03-25 Cydex, Inc. Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin
WO2006095026A2 (en) * 2005-03-11 2006-09-14 Altergon S.A. New soft gelatin capsules
WO2008025819A2 (en) * 2006-09-01 2008-03-06 Altergon S.A. Formulations of acetylsalicylic acid or its derivatives in soft capsules, exhibiting high stability

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62249935A (ja) 1986-04-18 1987-10-30 Toyo Kapuseru Kk サイクロデキストリンを含有する製剤用のゼラチン基質
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
ES2435816T3 (es) * 1999-08-03 2013-12-23 Icos Corporation Formulación farmacéutica que comprende una Beta-carbolina y su uso para el tratamiento de la disfunción sexual
CN102225055B (zh) * 2011-06-14 2012-05-23 贵州地道药业有限公司 一种软胶囊囊壳配方

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004024126A1 (en) * 2002-09-13 2004-03-25 Cydex, Inc. Capsules containing aqueous fill compositions stabilized with derivatized cyclodextrin
WO2006095026A2 (en) * 2005-03-11 2006-09-14 Altergon S.A. New soft gelatin capsules
WO2008025819A2 (en) * 2006-09-01 2008-03-06 Altergon S.A. Formulations of acetylsalicylic acid or its derivatives in soft capsules, exhibiting high stability

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
POSE-VILARNOVO B ET AL: "EFFECT OF HYDROXYPROPYLMETHYL CELLULOSE ON THE COMPLEXATION OF DICLOFENAC WITH CYCLODEXTRINS", JOURNAL OF THERMAL ANALYSIS AND CALORIM, KLUWER, DORDRECHT, NL, vol. 73, no. 1, 1 January 2003 (2003-01-01), pages 661 - 670, XP009030780, ISSN: 1388-6150, DOI: 10.1023/A:1025450718030 *

Also Published As

Publication number Publication date
EP3579880A1 (en) 2019-12-18
CN110214030B (zh) 2023-09-19
CN110214030A (zh) 2019-09-06
US20190374475A1 (en) 2019-12-12
RU2768630C2 (ru) 2022-03-24
CA3050347C (en) 2023-09-05
WO2018146237A1 (en) 2018-08-16
RU2019120281A (ru) 2021-03-10
CA3050347A1 (en) 2018-08-16
US11090271B2 (en) 2021-08-17
RU2019120281A3 (it) 2021-05-17
EP3579880B1 (en) 2024-07-03
DK3579880T3 (en) 2024-09-09

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