BR0313725A - derivados de lincomicina que possuem atividade antibacteriana - Google Patents

derivados de lincomicina que possuem atividade antibacteriana

Info

Publication number
BR0313725A
BR0313725A BRPI0313725-2A BR0313725A BR0313725A BR 0313725 A BR0313725 A BR 0313725A BR 0313725 A BR0313725 A BR 0313725A BR 0313725 A BR0313725 A BR 0313725A
Authority
BR
Brazil
Prior art keywords
antibacterial activity
derivatives
lincomycin derivatives
lincomycin
compounds
Prior art date
Application number
BRPI0313725-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Jason Lewis
Dinesh V Patel
Sampath K Anandan
Mikhail F Gordeev
Original Assignee
Vicuron Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vicuron Pharm Inc filed Critical Vicuron Pharm Inc
Publication of BR0313725A publication Critical patent/BR0313725A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
BRPI0313725-2A 2002-08-15 2003-08-15 derivados de lincomicina que possuem atividade antibacteriana BR0313725A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40377002P 2002-08-15 2002-08-15
PCT/US2003/025820 WO2004016632A2 (en) 2002-08-15 2003-08-15 Lincomycin derivatives possessing antibacterial activity

Publications (1)

Publication Number Publication Date
BR0313725A true BR0313725A (pt) 2006-06-13

Family

ID=31888275

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0313725-2A BR0313725A (pt) 2002-08-15 2003-08-15 derivados de lincomicina que possuem atividade antibacteriana

Country Status (15)

Country Link
US (1) US7164011B2 (enExample)
EP (1) EP1529052A2 (enExample)
JP (1) JP2006504673A (enExample)
KR (1) KR20050056195A (enExample)
CN (1) CN1315859C (enExample)
AU (1) AU2003265475B2 (enExample)
BR (1) BR0313725A (enExample)
CA (1) CA2493799A1 (enExample)
EA (1) EA200500353A1 (enExample)
IL (1) IL166476A (enExample)
MX (1) MXPA05001689A (enExample)
NO (1) NO20051289L (enExample)
NZ (1) NZ538141A (enExample)
WO (1) WO2004016632A2 (enExample)
ZA (1) ZA200501012B (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7199105B2 (en) 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
WO2004016632A2 (en) 2002-08-15 2004-02-26 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
US7256177B2 (en) 2003-06-17 2007-08-14 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
CA2528596A1 (en) * 2003-06-17 2005-01-27 Vicuron Pharmaceuticals Inc. Lincomycin derivatives possessing antibacterial activity
US7199106B2 (en) 2003-06-17 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antimicrobial activity
AU2004261550A1 (en) * 2003-06-17 2005-02-10 Vicuron Pharmaceuticals, Inc. Novel lincomycin derivatives possessing antimicrobial activity
US7361743B2 (en) 2004-02-11 2008-04-22 Pfizer Inc Lincomycin derivatives possessing antibacterial activity
JP5064237B2 (ja) * 2005-12-09 2012-10-31 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 リンコマイシン誘導体およびこれを有効成分とする抗菌剤
JP5356223B2 (ja) * 2007-05-31 2013-12-04 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 リンコマイシン誘導体及びこれを有効成分とする抗菌剤
US7867980B2 (en) * 2007-05-31 2011-01-11 Meiji Seika Kaisha, Ltd. Lincosamide derivatives and antimicrobial agents comprising the same as active ingredient
CN101555223B (zh) * 2009-04-17 2011-06-01 北京化工大学 一种吡利霉素中间体及其制备方法
US9533973B2 (en) 2011-12-08 2017-01-03 The Board Of Regents Of The University Of Texas System Allosteric modulators of 5-hydroxytryptamine 2C receptor (5-HT2CR)
CN105566411B (zh) * 2014-11-07 2020-11-13 中国科学院上海有机化学研究所 林可霉素生物合成中间产物及其制法和用途

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US29558A (en) * 1860-08-14 Bread-slicer
US2851463A (en) 1956-04-09 1958-09-09 Upjohn Co Desalicetin and salts, and hydrocarbon carboxylic acid esters
US2928844A (en) 1958-02-24 1960-03-15 Upjohn Co Celesticetin, its salts and method of preparation
US3086912A (en) 1961-07-03 1963-04-23 Upjohn Co Antibiotic lincolnensin and method of production
US3268556A (en) 1964-04-13 1966-08-23 Upjohn Co Novel lincomycin derivatives
US3255174A (en) 1964-04-13 1966-06-07 Upjohn Co 7-0-methyl-n-acyl-3, 4-o-isopropylidene-1-deoxy-lincosamines
NL128232C (enExample) 1964-04-13
NL146501C (enExample) 1964-07-01
US3764672A (en) 1964-08-05 1973-10-09 Upjohn Co Composition and process of treatment using lincomycin derivatives
US3380992A (en) 1965-06-14 1968-04-30 Upjohn Co Lincomycin derivatives and process for preparing same
US3282917A (en) 1964-08-17 1966-11-01 Upjohn Co Methyl n-(1-alkyl-4-alkoxy-prolyl)-alpha-thiolincosaminide compounds and process therefor
US3502648A (en) 1965-02-08 1970-03-24 Upjohn Co 7-halo-7-deoxythiolincosaminides and process for preparing the same
NL140527B (nl) 1965-02-08 1973-12-17 Upjohn Co Werkwijze ter bereiding van aan lincomycine verwante verbindingen.
US3496163A (en) 1965-02-08 1970-02-17 Upjohn Co 7-halo-7-deoxylincomycins and process for preparing the same
US3435025A (en) 1966-03-18 1969-03-25 Upjohn Co 7-deoxylincomycin and analogs and isomers thereof and process for making the same
US3475407A (en) 1967-12-22 1969-10-28 Upjohn Co Process for preparing 7(r)- and 7(s)-halolincomycins
US3509127A (en) 1968-04-30 1970-04-28 Upjohn Co Isologs of lincomycins and process for preparing the same
US3544551A (en) 1968-04-30 1970-12-01 Upjohn Co 7-mercapto-7-deoxylincomycins and process for preparing the same
US3555007A (en) 1968-07-22 1971-01-12 Upjohn Co 7-deoxy-7-halo lincomycin d derivatives
US3549615A (en) * 1968-10-17 1970-12-22 Upjohn Co Lincomycin derivatives and process for producing the same
US3702322A (en) * 1970-04-06 1972-11-07 Upjohn Co Derivatives of lincomycin and its analogs and process
DE2118636A1 (de) 1970-04-20 1971-11-04 The Upjohn Co., Kalamazoo, Mich. (V.StA.) 3-Nucleotide von Lincomycin und deren Analogen, Verfahren zu ihrer Herstellung und ihre Verwendung in therapeutischen Präparaten
US3692767A (en) 1970-05-06 1972-09-19 Upjohn Co Process for making lincomycin and analogs thereof and novel compounds obtained thereby
US3714141A (en) 1970-05-26 1973-01-30 Upjohn Co Process for making 7-halolincomycins
US3674647A (en) 1970-10-07 1972-07-04 Upjohn Co Preparation of lincomycin analogues
US3715346A (en) 1970-11-18 1973-02-06 Upjohn Co Process for the preparation of lincomycin compounds
US3671647A (en) 1971-03-24 1972-06-20 Upjohn Co Lincomycin 3-nucleotides and the salts thereof
US3892730A (en) 1971-06-23 1975-07-01 Upjohn Co 1{40 -({62 -hydroxyethyl)-1{40 -demethyl clindamycin 2-acylates
US3892729A (en) 1971-06-23 1975-07-01 Upjohn Co 1{40 (Beta-hydroxyethyl)-1{40 -demethyl clindamycin 2-phosphates
US3856943A (en) 1971-06-23 1974-12-24 Upjohn Co Compositions and process
US3787390A (en) 1971-06-23 1974-01-22 Upjohn Co Analogs of lincomycin and process
US3915954A (en) 1971-11-15 1975-10-28 Upjohn Co Derivatives of lincomycin and its analogs and process
BE793630A (fr) 1972-01-03 1973-07-03 Upjohn Co Nouvel antibiotique de la classe des celesticetines et son procede de preparation
US3853843A (en) 1972-12-13 1974-12-10 Upjohn Co Derivatives of thiolincosaminide compounds
US3849396A (en) 1973-01-08 1974-11-19 Upjohn Co Lincomycin and clindamycin 1-o-ethers
US3870699A (en) 1973-03-06 1975-03-11 Upjohn Co Lincomycin analogs
US3833475A (en) 1973-04-23 1974-09-03 Upjohn Co Process for preparing lincomycin
US4271266A (en) 1974-06-10 1981-06-02 The Upjohn Manufacturing Company Process for preparing lincomycin
US4031304A (en) 1976-01-30 1977-06-21 The Upjohn Company Process for preparing lincomycin derivatives
US4278789A (en) 1979-11-23 1981-07-14 The Upjohn Company Lincomycin compounds
US4309533A (en) 1980-05-19 1982-01-05 The Upjohn Company Lincomycin compounds
US4310660A (en) 1980-05-19 1982-01-12 The Upjohn Company Lincomycin compounds
US4293547A (en) 1980-08-25 1981-10-06 The Upjohn Company Method of treating malaria
US4317903A (en) 1981-01-26 1982-03-02 The Upjohn Company Process for the purification of lincomycin
US4383109A (en) 1981-04-20 1983-05-10 The Upjohn Company Lincomycin nucleotides
US4464466A (en) 1981-04-20 1984-08-07 The Upjohn Company Process of producing lincomycin nucleotides
US4430495A (en) 1982-09-17 1984-02-07 The Upjohn Company Process for preparing lincomycin and clindamycin ribonucleotides
US4568741A (en) 1984-05-15 1986-02-04 The Upjohn Company Synthesis of 7-halo-7-deoxylincomycins
CN1004002B (zh) 1984-11-29 1989-04-26 厄普约翰公司 制备7-卤-7-去氧林可霉素及其类似化合物的改进方法
WO1989004672A1 (en) 1987-11-20 1989-06-01 The Upjohn Company Derivatives of lincosaminide antibiotics
AU4543899A (en) 1998-06-08 1999-12-30 Advanced Medicine, Inc. Multibinding inhibitors of microsomal triglyceride transferase protein
WO2004016632A2 (en) 2002-08-15 2004-02-26 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
US7199105B2 (en) 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
AU2004261550A1 (en) 2003-06-17 2005-02-10 Vicuron Pharmaceuticals, Inc. Novel lincomycin derivatives possessing antimicrobial activity
CA2528596A1 (en) 2003-06-17 2005-01-27 Vicuron Pharmaceuticals Inc. Lincomycin derivatives possessing antibacterial activity

Also Published As

Publication number Publication date
IL166476A (en) 2010-05-31
AU2003265475A1 (en) 2004-03-03
WO2004016632A3 (en) 2004-06-24
EA200500353A1 (ru) 2006-06-30
CN1315859C (zh) 2007-05-16
WO2004016632A2 (en) 2004-02-26
NO20051289L (no) 2005-05-09
US20040116690A1 (en) 2004-06-17
CA2493799A1 (en) 2004-02-26
NZ538141A (en) 2007-06-29
EP1529052A2 (en) 2005-05-11
CN1681832A (zh) 2005-10-12
KR20050056195A (ko) 2005-06-14
US7164011B2 (en) 2007-01-16
ZA200501012B (en) 2006-10-25
IL166476A0 (en) 2006-01-15
WO2004016632A8 (en) 2004-09-30
WO2004016632B1 (en) 2004-08-19
AU2003265475B2 (en) 2009-08-27
MXPA05001689A (es) 2005-05-27
JP2006504673A (ja) 2006-02-09

Similar Documents

Publication Publication Date Title
BRPI0411534A (pt) derivados de lincomicina com atividade antimicrobiana
BR0313725A (pt) derivados de lincomicina que possuem atividade antibacteriana
EP2279662A3 (en) 5,7,4'-trihydroxy-3',5'-dimethoxyflavone as an antibacterial agent
NO996269L (no) Kinolin-indol antimikrobielle midler, samt anvendelse og blandinger derav
EP3738591A3 (en) Novel antibacterial agents
BR0012674A (pt) Formulações farmacêuticas preservadas
WO2007064954A3 (en) Antibacterial 4,5-substituted aminoglycoside analogs having multiple substituents
UY26269A1 (es) Formulación de sal común y moxifloxacina
BR0213063A (pt) Antibióticos de ação dupla
SE0201544D0 (sv) Novel compounds and thier use
AU2119200A (en) Medicament
HUP0102515A2 (hu) Ciklopeptidek, eljárás előállításukra, hatóanyagként azokat tartalmazó gyógyszerkészítmények és alkalmazásuk
EA200600971A1 (ru) Применение замещённых 2 - аминотетралинов для профилактического лечения болезни паркинсона
ES2243579T3 (es) Derivados de pirazolopirideno.
BR0315139A (pt) Agentes antibacterianos de tetraidroquinolina tricìclica
BR0308135A (pt) Derivados de alquilaminopirazol 5-substituìdos como pesticidas
WO2006055070A3 (en) Novel lincomycin derivatives possessing antibacterial activity
WO2007001335A3 (en) Ramoplanin derivatives possessing antibacterial activity
ES2178761T3 (es) Utilizacion de 1-hidroxi-2-piridonas para el tratamiento de infe cciones cutaneas.
TW200724166A (en) Wrinkle-improving agent
BRPI0317188A2 (pt) Novo derivado de 2,4-diamino-1,3,5-triazina
AU2002357740A1 (en) Pyrazolo-pyridine derivatives as antiherpes agents
WO2005007665A8 (en) Lincomycin derivatives possessing antibacterial activity
BR0102940A (pt) Agente para o tratamento de doença de parkinson compreendendo um agente de melhora da função de astrócitos como ingrediente ativo
DE60130009D1 (de) Makrolide

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8AANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.