BR0313725A - derivados de lincomicina que possuem atividade antibacteriana - Google Patents

derivados de lincomicina que possuem atividade antibacteriana

Info

Publication number
BR0313725A
BR0313725A BRPI0313725-2A BR0313725A BR0313725A BR 0313725 A BR0313725 A BR 0313725A BR 0313725 A BR0313725 A BR 0313725A BR 0313725 A BR0313725 A BR 0313725A
Authority
BR
Brazil
Prior art keywords
antibacterial activity
derivatives
lincomycin derivatives
lincomycin
compounds
Prior art date
Application number
BRPI0313725-2A
Other languages
English (en)
Inventor
Jason Lewis
Dinesh V Patel
Sampath K Anandan
Mikhail F Gordeev
Original Assignee
Vicuron Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vicuron Pharm Inc filed Critical Vicuron Pharm Inc
Publication of BR0313725A publication Critical patent/BR0313725A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C07H15/16—Lincomycin; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

"DERIVADOS DE LINCOMICINA QUE POSSUEM ATIVIDADE ANTIBACTERIANA". A presente invenção refere-se a derivados de lincomicina que são descritos. Estes derivados de lincomicina apresentam atividade anti-bacteriana. Quando os compostos da invenção objeto apresentam atividades potentes contra bactérias, incluindo organismos Gram positivos, eles são agentes antimicrobianos úteis. Os métodos de síntese e de uso dos compostos são também apresentados.
BRPI0313725-2A 2002-08-15 2003-08-15 derivados de lincomicina que possuem atividade antibacteriana BR0313725A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40377002P 2002-08-15 2002-08-15
PCT/US2003/025820 WO2004016632A2 (en) 2002-08-15 2003-08-15 Lincomycin derivatives possessing antibacterial activity

Publications (1)

Publication Number Publication Date
BR0313725A true BR0313725A (pt) 2006-06-13

Family

ID=31888275

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0313725-2A BR0313725A (pt) 2002-08-15 2003-08-15 derivados de lincomicina que possuem atividade antibacteriana

Country Status (15)

Country Link
US (1) US7164011B2 (pt)
EP (1) EP1529052A2 (pt)
JP (1) JP2006504673A (pt)
KR (1) KR20050056195A (pt)
CN (1) CN1315859C (pt)
AU (1) AU2003265475B2 (pt)
BR (1) BR0313725A (pt)
CA (1) CA2493799A1 (pt)
EA (1) EA200500353A1 (pt)
IL (1) IL166476A (pt)
MX (1) MXPA05001689A (pt)
NO (1) NO20051289L (pt)
NZ (1) NZ538141A (pt)
WO (1) WO2004016632A2 (pt)
ZA (1) ZA200501012B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA05001689A (es) 2002-08-15 2005-05-27 Vicuron Pharm Inc Derivados de lincomicina que poseen actividad antibacteriana.
US7199105B2 (en) 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
CA2528596A1 (en) * 2003-06-17 2005-01-27 Vicuron Pharmaceuticals Inc. Lincomycin derivatives possessing antibacterial activity
EP1644393A2 (en) * 2003-06-17 2006-04-12 Vicuron Pharmaceuticals, Inc. Novel lincomycin derivatives possessing antimicrobial activity
US7199106B2 (en) 2003-06-17 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antimicrobial activity
US7256177B2 (en) 2003-06-17 2007-08-14 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
US7361743B2 (en) * 2004-02-11 2008-04-22 Pfizer Inc Lincomycin derivatives possessing antibacterial activity
EP1970377A4 (en) * 2005-12-09 2013-02-27 Meiji Seika Kaisha LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THIS AS AN ACTIVE SUBSTANCE
JP5356223B2 (ja) * 2007-05-31 2013-12-04 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 リンコマイシン誘導体及びこれを有効成分とする抗菌剤
JP5290166B2 (ja) * 2007-05-31 2013-09-18 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 リンコサミド誘導体及びこれを有効成分とする抗菌剤
CN101555223B (zh) * 2009-04-17 2011-06-01 北京化工大学 一种吡利霉素中间体及其制备方法
CA2871766C (en) 2011-12-08 2020-06-16 The Board Of Regents Of The University Of Texas System Piperidine-based small molecule 5-hydroxytryptamine 2c receptor (5-ht2cr) allosteric modulators
CN105566411B (zh) * 2014-11-07 2020-11-13 中国科学院上海有机化学研究所 林可霉素生物合成中间产物及其制法和用途

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US2928844A (en) * 1958-02-24 1960-03-15 Upjohn Co Celesticetin, its salts and method of preparation
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DE2118636A1 (de) 1970-04-20 1971-11-04 The Upjohn Co., Kalamazoo, Mich. (V.StA.) 3-Nucleotide von Lincomycin und deren Analogen, Verfahren zu ihrer Herstellung und ihre Verwendung in therapeutischen Präparaten
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MXPA05001689A (es) 2002-08-15 2005-05-27 Vicuron Pharm Inc Derivados de lincomicina que poseen actividad antibacteriana.
US7199105B2 (en) * 2002-08-15 2007-04-03 Vicuron Pharmaceuticals, Inc. Lincomycin derivatives possessing antibacterial activity
CA2528596A1 (en) 2003-06-17 2005-01-27 Vicuron Pharmaceuticals Inc. Lincomycin derivatives possessing antibacterial activity
EP1644393A2 (en) 2003-06-17 2006-04-12 Vicuron Pharmaceuticals, Inc. Novel lincomycin derivatives possessing antimicrobial activity

Also Published As

Publication number Publication date
AU2003265475B2 (en) 2009-08-27
CA2493799A1 (en) 2004-02-26
MXPA05001689A (es) 2005-05-27
CN1315859C (zh) 2007-05-16
IL166476A (en) 2010-05-31
JP2006504673A (ja) 2006-02-09
WO2004016632B1 (en) 2004-08-19
ZA200501012B (en) 2006-10-25
CN1681832A (zh) 2005-10-12
NO20051289L (no) 2005-05-09
NZ538141A (en) 2007-06-29
WO2004016632A2 (en) 2004-02-26
EA200500353A1 (ru) 2006-06-30
AU2003265475A1 (en) 2004-03-03
IL166476A0 (en) 2006-01-15
WO2004016632A3 (en) 2004-06-24
KR20050056195A (ko) 2005-06-14
US7164011B2 (en) 2007-01-16
WO2004016632A8 (en) 2004-09-30
EP1529052A2 (en) 2005-05-11
US20040116690A1 (en) 2004-06-17

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A E 8AANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2129 DE 25/10/2011.