BR0012674A - Formulações farmacêuticas preservadas - Google Patents

Formulações farmacêuticas preservadas

Info

Publication number
BR0012674A
BR0012674A BR0012674-8A BR0012674A BR0012674A BR 0012674 A BR0012674 A BR 0012674A BR 0012674 A BR0012674 A BR 0012674A BR 0012674 A BR0012674 A BR 0012674A
Authority
BR
Brazil
Prior art keywords
pharmaceutical formulations
preserved pharmaceutical
phenoxyethanol
alone
combination
Prior art date
Application number
BR0012674-8A
Other languages
English (en)
Inventor
Atef Gayed
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of BR0012674A publication Critical patent/BR0012674A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"FORMULAçõES FARMACêUTICAS PRESERVADAS". A presente invenção refere-se ao uso do cloreto de benzotónio, isolado ou em combinação com fenoxietanol ou álcool feniletílico, para proporcionar uma atividade antimicrobiana em composições farmacêuticas. A presente invenção proporciona também métodos de usar o cloreto de benzetónio, isolado ou em combinação com fenoxietanol ou álcool feniletílico, para inibir crescimento microbiano em composição farmacêuticas.
BR0012674-8A 1999-07-22 2000-07-21 Formulações farmacêuticas preservadas BR0012674A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22881599P 1999-07-22 1999-07-22
PCT/US2000/020040 WO2001007086A1 (en) 1999-07-22 2000-07-21 Preserved pharmaceutical formulations

Publications (1)

Publication Number Publication Date
BR0012674A true BR0012674A (pt) 2002-09-17

Family

ID=22858657

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0012674-8A BR0012674A (pt) 1999-07-22 2000-07-21 Formulações farmacêuticas preservadas

Country Status (21)

Country Link
US (1) US7109161B1 (pt)
EP (1) EP1200128A1 (pt)
JP (1) JP2003520777A (pt)
KR (2) KR20070116181A (pt)
CN (1) CN1371287A (pt)
AU (1) AU777410C (pt)
BR (1) BR0012674A (pt)
CA (1) CA2378892C (pt)
CZ (1) CZ2002265A3 (pt)
EA (1) EA007070B1 (pt)
EE (1) EE200200038A (pt)
HK (1) HK1050317A1 (pt)
HR (1) HRP20020160A2 (pt)
HU (1) HUP0202235A3 (pt)
IL (1) IL147756A (pt)
NO (1) NO20020304L (pt)
NZ (1) NZ516736A (pt)
PL (1) PL353026A1 (pt)
WO (1) WO2001007086A1 (pt)
YU (1) YU4602A (pt)
ZA (1) ZA200200743B (pt)

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IL147756A (en) 1999-07-22 2005-12-18 Aventis Pharma Inc Preserved pharmaceutical formulations
US20020107469A1 (en) * 2000-11-03 2002-08-08 Charles Bolan Apheresis methods and devices
EP1894591B1 (en) 2002-03-20 2013-06-26 MannKind Corporation Cartridge for an inhalation apparatus
US20050244517A1 (en) * 2003-11-05 2005-11-03 Santarus, Inc. Combination of proton pump inhibitor and sleep aid
DE202004020676U1 (de) * 2004-03-10 2005-11-10 Bioceuticals Arzneimittel Ag Erythropoietin-Flüssigformulierung
US8338648B2 (en) 2004-06-12 2012-12-25 Signum Biosciences, Inc. Topical compositions and methods for epithelial-related conditions
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
CN104436170B (zh) 2004-08-23 2018-02-23 曼金德公司 用于药物输送的二酮哌嗪盐
US9028852B2 (en) 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
HUE028623T2 (en) 2005-09-14 2016-12-28 Mannkind Corp Active substance formulation method based on increasing the affinity of the active ingredient for binding to the surface of crystalline microparticles
IN2015DN00888A (pt) 2006-02-22 2015-07-10 Mannkind Corp
MX2008013407A (es) 2006-04-18 2009-03-09 Ekr Therapeutics Inc Composiciones de bolo iv premezcladas, listas para uso y metodos de uso.
WO2008057802A2 (en) 2006-10-27 2008-05-15 The Curators Of The University Of Missouri Compositions comprising at least one acid labile proton pump inhibiting agents, optionally other pharmaceutically active agents and methods of using same
US20090069418A1 (en) * 2007-04-25 2009-03-12 Alkayed Nabil J Compositions and Methods for the Treatment of Disorders Associated with Aberrant Vasodilation
DE102007054794A1 (de) * 2007-11-13 2009-05-14 Agilan Gmbh Wässrige Eisen-Dextran-Zubereitung mit ein oder mehreren Verbindungen der para-Hydroxy-Benzoesäureester und/oder deren Salzen
US20090170917A1 (en) * 2007-12-03 2009-07-02 Seung-Yub Lee Acid Mimic Compounds for the Inhibition of Isoprenyl-S-Cysteinyl Methyltransferase
CN101980700A (zh) 2008-02-20 2011-02-23 密苏里大学董事会 包含奥美拉唑和兰索拉唑以及缓冲剂的组合的组合物及其使用方法
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
ES2570400T3 (es) 2008-06-13 2016-05-18 Mannkind Corp Un inhalador de polvo seco y un sistema para el suministro de fármacos
JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
CA2738524C (en) 2008-10-02 2013-11-26 Mylan Inc. Method for making a multilayer adhesive laminate
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
TW201138782A (en) * 2010-04-26 2011-11-16 Besins Healthcare Lu Sarl Low-oil pharmaceutical emulsion compositions comprising progestogen
MX359281B (es) 2010-06-21 2018-09-21 Mannkind Corp Sistema y metodos para suministrar un farmaco en polvo seco.
KR101805087B1 (ko) * 2010-09-16 2017-12-05 주식회사 엘지화학 높은 방부력을 제공하는 오일 주사 제형
MX353285B (es) * 2011-04-01 2018-01-05 Mannkind Corp Paquete de blister para cartuchos farmaceuticos.
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
US20130011494A1 (en) * 2011-07-10 2013-01-10 Mohammad Rahimi Composition for treating decubitus ulcers in diabetic and non-diabetic patients
CN102993031B (zh) 2011-09-19 2014-03-26 北京桑普生物化学技术有限公司 一种制备芳基多氧烷基季铵类化合物的方法
CN103945859A (zh) 2011-10-24 2014-07-23 曼金德公司 用于治疗疼痛的方法和组合物
WO2014012069A2 (en) 2012-07-12 2014-01-16 Mannkind Corporation Dry powder drug delivery systems and methods
KR102321339B1 (ko) 2013-07-18 2021-11-02 맨카인드 코포레이션 열-안정성 건조 분말 약제학적 조성물 및 방법
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
DE102016000277A1 (de) 2016-01-15 2017-07-20 Beiersdorf Ag Kosmetische Zubereitungen enthaltend Benzethonium Chlorid und Diole
EP3554233A4 (en) * 2016-12-16 2020-07-22 Vertellus Holdings LLC QUATERNARY AMINE FORMULATIONS AND USES THEREOF
US11364225B2 (en) * 2019-08-21 2022-06-21 Bn Intellectual Properties, Inc. Pharmaceutical formulation for treating symptoms of migraine and cluster headaches, and method of using the same

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US3489837A (en) * 1968-07-11 1970-01-13 Leroy J Hyman Synergistic antiseptic composition consisting of 9-aminoacridine hydrochloride and benzethonium chloride
US4053628A (en) 1971-05-12 1977-10-11 Fisons Limited Composition
JPS6045849B2 (ja) 1980-08-25 1985-10-12 林原 健 ヒトエリトロポエチンの製造方法
US4506018A (en) 1982-12-30 1985-03-19 Becton, Dickinson And Company Blood diluent
US4703008A (en) 1983-12-13 1987-10-27 Kiren-Amgen, Inc. DNA sequences encoding erythropoietin
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BR0012667A (pt) 1999-07-22 2002-07-02 Aventis Pharma Inc Formulações de eritropoietina de multi-doses

Also Published As

Publication number Publication date
AU777410C (en) 2006-08-17
KR20020032534A (ko) 2002-05-03
NO20020304L (no) 2002-03-21
HRP20020160A2 (en) 2003-10-31
KR20070116181A (ko) 2007-12-06
EA200200072A1 (ru) 2003-02-27
HUP0202235A3 (en) 2004-05-28
NZ516736A (en) 2004-02-27
PL353026A1 (en) 2003-10-06
YU4602A (sh) 2005-06-10
CA2378892C (en) 2008-07-15
AU777410B2 (en) 2004-10-14
CN1371287A (zh) 2002-09-25
CZ2002265A3 (cs) 2002-08-14
US7109161B1 (en) 2006-09-19
JP2003520777A (ja) 2003-07-08
NO20020304D0 (no) 2002-01-21
CA2378892A1 (en) 2001-02-01
EP1200128A1 (en) 2002-05-02
IL147756A0 (en) 2002-08-14
EA007070B1 (ru) 2006-06-30
HK1050317A1 (zh) 2003-06-20
HUP0202235A2 (hu) 2002-11-28
EE200200038A (et) 2003-04-15
WO2001007086A1 (en) 2001-02-01
ZA200200743B (en) 2003-06-25
AU6232500A (en) 2001-02-13
IL147756A (en) 2005-12-18

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: AVENTIS PHARMACEUTICALS, INC. (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070165509/RJ DE 23/11/2007.

B25A Requested transfer of rights approved

Owner name: HMR PHARMA, INC. (US)

Free format text: TRANSFERIDO DE: AVENTIS PHARMACEUTICALS, INC.

B25A Requested transfer of rights approved

Owner name: AVENTIS HOLDINGS INC. (US)

Free format text: TRANSFERIDO DE: HMR PHARMA, INC.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA.INT.CI.461K 47/18, A61K 47/10, A61P 31/00

Ipc: A61K 47/18 (2011.01), A61K 47/10 (2011.01), A61P 3

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2156 DE 02/05/2012.