BR0312365A - Meio de cultura autólogo de células-mães progenitoras autólogas humanas, métodos para a preparação do mesmo e de uma composição de células-mães progenitoras autólogas humanas e para a obtenção de células-mães progenitoras musculares autólogas humanas, emprego de um meio de cultura autólogo de células-mães progenitoras autólogas humanas, procedimento para a obtenção de células-mães progenitoras musculares autólogas humanas e procedimento terapêutico de cardiomioplastia celular autóloga, composição enriquecida com células-mães progenitoras musculares autólogas humanas e composição farmacêutica - Google Patents

Meio de cultura autólogo de células-mães progenitoras autólogas humanas, métodos para a preparação do mesmo e de uma composição de células-mães progenitoras autólogas humanas e para a obtenção de células-mães progenitoras musculares autólogas humanas, emprego de um meio de cultura autólogo de células-mães progenitoras autólogas humanas, procedimento para a obtenção de células-mães progenitoras musculares autólogas humanas e procedimento terapêutico de cardiomioplastia celular autóloga, composição enriquecida com células-mães progenitoras musculares autólogas humanas e composição farmacêutica

Info

Publication number
BR0312365A
BR0312365A BR0312365-0A BR0312365A BR0312365A BR 0312365 A BR0312365 A BR 0312365A BR 0312365 A BR0312365 A BR 0312365A BR 0312365 A BR0312365 A BR 0312365A
Authority
BR
Brazil
Prior art keywords
autologous
progenitor
human
mother
mother cells
Prior art date
Application number
BR0312365-0A
Other languages
English (en)
Inventor
Juan Carlos Chacques
Felipe Prosper Cardoso
Jesus Herreros Gonzalez
Original Assignee
Inst Cientifico Tecnol Navarra
Juan Carlos Chacques
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Cientifico Tecnol Navarra, Juan Carlos Chacques filed Critical Inst Cientifico Tecnol Navarra
Publication of BR0312365A publication Critical patent/BR0312365A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0658—Skeletal muscle cells, e.g. myocytes, myotubes, myoblasts
    • C12N5/0659—Satellite cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/90—Polysaccharides
    • C12N2501/91—Heparin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"MEIO DE CULTURA AUTóLOGO DE CéLULAS-MãES PROGENITORAS AUTóLOGAS HUMANAS., MéTODOS PARA A PREPARAçãO DO MESMO E DE UMA COMPOSIçãO DE CéLULAS-MãES PROGENITORAS AUTóLOGAS HUMANAS E PARA A OBTENçãO DE CéLULAS-MãES PROGENITORAS MUSCULARES AUTóLOGAS HUMANAS, EMPREGO DE UM MEIO DE CULTURA AUTóLOGO DE CELULAS-MãES PROGENITORAS AUTOLOGAS HUMANAS, PROCEDIMENTO PARA A OBTENçãO DE CéLULAS-MãES PROGENITORAS MUSCULARES AUTóLOGAS HUMANAS E PROCEDIMENTO TERAPêUTICO DE CARDIOMIOPLASTIA CELULAR AUTóLOGA, COMPOSIçãO ENRIQUECIDA COM CELULAS-MãES PROGENITORAS MUSCULARES AUTóLOGAS HUMANAS E COMPOSIçãO FARMACêUTICA". O meio de cultura autólogo de células-mãe progenitoras autólogas humanas compreende: entre 0,1 % e 90 % em peso de soro humano autólogo; entre 0,1 e 10.000 UI/ml de heparina; entre 0,1 e 10.000 UI/ml de protamina; e um meio de cultura com nutrientes básicos com ou sem glutamina, em quantidade suficiente até 100 % em peso, e é útil para cultivar e expandir células-mãe progenitoras autólogas humanas. Composições contendo referidas células podem ser implantadas no paciente mediante um procedimento de cardiomioplastia celular autóloga para criar, regenerar e reparar tecido miocárdico disfuncional.
BR0312365-0A 2002-07-02 2003-06-11 Meio de cultura autólogo de células-mães progenitoras autólogas humanas, métodos para a preparação do mesmo e de uma composição de células-mães progenitoras autólogas humanas e para a obtenção de células-mães progenitoras musculares autólogas humanas, emprego de um meio de cultura autólogo de células-mães progenitoras autólogas humanas, procedimento para a obtenção de células-mães progenitoras musculares autólogas humanas e procedimento terapêutico de cardiomioplastia celular autóloga, composição enriquecida com células-mães progenitoras musculares autólogas humanas e composição farmacêutica BR0312365A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200201540A ES2198216B1 (es) 2002-07-02 2002-07-02 Medio de cultivo de celulas madre-progenitoras autologas humanas y sus aplicaciones.
PCT/ES2003/000285 WO2004005494A1 (es) 2002-07-02 2003-06-11 Medio de cultivo de células madre-progenitoras autólogas humanas y sus aplicaciones

Publications (1)

Publication Number Publication Date
BR0312365A true BR0312365A (pt) 2005-04-05

Family

ID=30011351

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0312365-0A BR0312365A (pt) 2002-07-02 2003-06-11 Meio de cultura autólogo de células-mães progenitoras autólogas humanas, métodos para a preparação do mesmo e de uma composição de células-mães progenitoras autólogas humanas e para a obtenção de células-mães progenitoras musculares autólogas humanas, emprego de um meio de cultura autólogo de células-mães progenitoras autólogas humanas, procedimento para a obtenção de células-mães progenitoras musculares autólogas humanas e procedimento terapêutico de cardiomioplastia celular autóloga, composição enriquecida com células-mães progenitoras musculares autólogas humanas e composição farmacêutica

Country Status (13)

Country Link
US (1) US20060110368A1 (pt)
EP (1) EP1972684A1 (pt)
JP (1) JP5379340B2 (pt)
KR (2) KR100960173B1 (pt)
CN (1) CN100572527C (pt)
AU (1) AU2003240857B2 (pt)
BR (1) BR0312365A (pt)
ES (1) ES2198216B1 (pt)
IL (1) IL165969A0 (pt)
MX (1) MXPA04012601A (pt)
NZ (1) NZ537397A (pt)
RU (1) RU2312141C2 (pt)
WO (1) WO2004005494A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7253735B2 (en) 2003-03-24 2007-08-07 Alien Technology Corporation RFID tags and processes for producing RFID tags
DE102004025684A1 (de) 2004-04-29 2005-11-17 Osram Opto Semiconductors Gmbh Optoelektronischer Halbleiterchip und Verfahren zum Ausbilden einer Kontaktstruktur zur elektrischen Kontaktierung eines optoelektronischen Halbleiterchips
EA014166B1 (ru) * 2005-12-13 2010-10-29 Киото Юниверсити Ядерный фактор перепрограммирования
CN101802174B (zh) * 2007-09-11 2013-06-05 北海道公立大学法人札幌医科大学 细胞增殖方法以及用于组织修复及再生的药物
RU2524655C2 (ru) * 2008-03-28 2014-07-27 Лабо Дзюверса Ко., Лтд. Средство для лечения старения кожи и рубцов
RU2493250C2 (ru) * 2011-07-08 2013-09-20 Общество с ограниченной ответственностью Научно-производственное предприятие "ПанЭко" Малосывороточная среда для культивирования фибробластов человека
JP5598864B2 (ja) * 2011-12-05 2014-10-01 北海道公立大学法人 札幌医科大学 細胞増殖方法ならびに組織の修復および再生のための医薬
RU2506309C2 (ru) * 2012-03-11 2014-02-10 Екатерина Алексеевна Федорова Способ культивирования миобластов in vitro для получения биомассы миоцитов для пищевых целей
TWI643953B (zh) * 2014-12-11 2018-12-11 訊聯生物科技股份有限公司 以自體血漿培養原始細胞的方法
CN106110304A (zh) * 2016-07-28 2016-11-16 广州赛莱拉干细胞科技股份有限公司 一种祛疤组合物和敷料
KR102093810B1 (ko) * 2017-09-19 2020-03-26 서울대학교산학협력단 면역원성 감소 방법
CA3137836C (en) * 2019-04-23 2024-04-09 Cellatoz Therapeutics, Inc. Method for regulation of selective differentiation of musculoskeletal stem cells
CN112501035B (zh) * 2020-12-09 2022-09-20 云南大学 基于捕食线虫真菌细胞膜破裂和内体增多而产生捕食器官的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735726A (en) * 1981-07-22 1988-04-05 E. I. Du Pont De Nemours And Company Plasmapheresis by reciprocatory pulsatile filtration
US4668399A (en) * 1982-02-16 1987-05-26 E. I. Du Pont De Nemours And Company Hollow fiber plasmapheresis process
US5612211A (en) * 1990-06-08 1997-03-18 New York University Stimulation, production and culturing of hematopoietic progenitor cells by fibroblast growth factors
NL9101680A (nl) * 1991-10-04 1993-05-03 Tno Werkwijze voor het genetisch modificeren van beenmergcellen van primaten, alsmede daarbij bruikbare cellen die recombinante retrovirale vectoren produceren.
JPH06113829A (ja) * 1992-10-09 1994-04-26 Tabai Espec Corp 動物細胞培地添加血清の調製方法、動物細胞培地の調製方法及び培養装置
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
CA2283641A1 (en) * 1997-03-18 1998-09-24 Introgene B.V. Methods and compositions for genetically modifying primate bone marrow cells
EP1007092B1 (en) * 1997-08-26 2006-08-09 Amgen Fremont Inc. A process for inhibiting complement activation via the alternative pathway
US6962698B1 (en) * 1998-02-17 2005-11-08 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
US6624141B1 (en) * 1999-03-17 2003-09-23 The Regents Of The University Of Michigan Protamine fragment compositions and methods of use
US6673604B1 (en) * 1999-07-23 2004-01-06 Diacrin, Inc. Muscle cells and their use in cardiac repair
US7015037B1 (en) * 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US20020124855A1 (en) * 2001-03-12 2002-09-12 Chachques Juan C. Method of providing a dynamic cellular cardiac support
US20030044766A1 (en) * 2001-08-29 2003-03-06 Anne Scholz Methods and devices for detecting cell-cell interactions

Also Published As

Publication number Publication date
KR20080091874A (ko) 2008-10-14
RU2005102061A (ru) 2005-10-10
US20060110368A1 (en) 2006-05-25
JP5379340B2 (ja) 2013-12-25
KR20050037549A (ko) 2005-04-22
AU2003240857A1 (en) 2004-01-23
JP2005531322A (ja) 2005-10-20
EP1972684A1 (en) 2008-09-24
ES2198216B1 (es) 2005-04-16
RU2312141C2 (ru) 2007-12-10
IL165969A0 (en) 2006-01-15
KR100960173B1 (ko) 2010-05-26
CN100572527C (zh) 2009-12-23
WO2004005494A1 (es) 2004-01-15
NZ537397A (en) 2008-09-26
MXPA04012601A (es) 2005-09-30
AU2003240857B2 (en) 2008-06-26
CN1665922A (zh) 2005-09-07
ES2198216A1 (es) 2004-01-16

Similar Documents

Publication Publication Date Title
Mansilla et al. Human mesenchymal stem cells are tolerized by mice and improve skin and spinal cord injuries
BR0210599A (pt) Uso de monóxido de carbono, método para manutenção de uma célula animal in vitro, artigo de manufatura, bem como meio celular estéril
BR0313197A (pt) Agentes citotóxicos contendo potentes taxanos e seu uso terapêutico
BR0312365A (pt) Meio de cultura autólogo de células-mães progenitoras autólogas humanas, métodos para a preparação do mesmo e de uma composição de células-mães progenitoras autólogas humanas e para a obtenção de células-mães progenitoras musculares autólogas humanas, emprego de um meio de cultura autólogo de células-mães progenitoras autólogas humanas, procedimento para a obtenção de células-mães progenitoras musculares autólogas humanas e procedimento terapêutico de cardiomioplastia celular autóloga, composição enriquecida com células-mães progenitoras musculares autólogas humanas e composição farmacêutica
Weil et al. Mesenchymal stem cells enhance the viability and proliferation of human fetal intestinal epithelial cells following hypoxic injury via paracrine mechanisms
EA200600076A1 (ru) Композиции и способы увеличения активности теломеразы
BRPI0516969A (pt) método de preparar uma composição terapêutica, composição terapêutica, e, método de tratar um paciente humano sofrendo de hematopoiese deficiente
WO2003068937A3 (en) Embryonic-like stem cells derived from post-partum mammalian placenta and uses and methods of treatment using said cells
WO2000006704A3 (en) Hematopoietic cell composition for use in transplantation
BRPI0410185A (pt) composição para manter a viabilidade de um orgão e célula
EP2418271A3 (en) Methods and compositions for treatment of bone defects with placental cell populations
AU2003209259A8 (en) Novel mammalian multipotent stem cells and compositions, methods of preparation and methods of administration thereof
EP2422803A3 (en) Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation
DK1326654T3 (da) Fremgangsmåder og sammensætninger til vævsregeneration
AR046485A1 (es) Sistema de administracion para drogas y terapia celular
WO2005065419A2 (en) Method of culturing cells
WO2003105908A3 (en) METHODS AND COMPOSITIONS USING CELL ASIALODETERMINANTS AND GLYCOCONJUGATES FOR PROVIDING CELLS TO TISSUES AND ORGANS
WO2001007568A3 (en) Muscle cells and their use in cardiac repair
WO2002076285A3 (en) Composition and methods fro the production of biological tissues and tissue constructs
Marbán et al. Heart to heart: cardiospheres for myocardial regeneration
Mangir et al. Stem cell therapies in post-prostatectomy erectile dysfunction: a critical review
US20200093726A1 (en) Compound additive having biological activation function, preparation method therefor and use thereof
BR112021013158A2 (pt) Método para tratar a dor lombar
WO2003080798A3 (en) Muscle cells and their use in cardiac repair
KR101859499B1 (ko) 세포외기질을 모사한 지방유래 줄기세포의 줄기세포성 증진용 조성물

Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: INSTITUTO CIENTIFICO Y TECNOLOGICO DE NAVARRA, S.A

Free format text: TRANSFERIDO DE: JUAN CARLOS CHACQUES

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 12A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2310 DE 14-04-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B15K Others concerning applications: alteration of classification

Ipc: C12N 5/077 (2010.01), A61K 35/12 (2015.01), A61P 2