BR0312002A - Composição para solubilização de paclitaxel e método de preparação da mesma - Google Patents
Composição para solubilização de paclitaxel e método de preparação da mesmaInfo
- Publication number
- BR0312002A BR0312002A BR0312002-3A BR0312002A BR0312002A BR 0312002 A BR0312002 A BR 0312002A BR 0312002 A BR0312002 A BR 0312002A BR 0312002 A BR0312002 A BR 0312002A
- Authority
- BR
- Brazil
- Prior art keywords
- paclitaxel
- composition
- weight
- preparation
- present
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2002-0042791 | 2002-07-20 | ||
KR10-2002-0042791A KR100533458B1 (ko) | 2002-07-20 | 2002-07-20 | 파클리탁셀의 가용화용 조성물 및 그의 제조 방법 |
PCT/KR2003/001427 WO2004009075A1 (en) | 2002-07-20 | 2003-07-18 | Composition for solubilization of paclitaxel and preparation method thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0312002A true BR0312002A (pt) | 2005-05-03 |
BRPI0312002B1 BRPI0312002B1 (pt) | 2017-11-28 |
Family
ID=36386602
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0312002A BRPI0312002B8 (pt) | 2002-07-20 | 2003-07-18 | composição para solubilização de paclitaxel e método de preparação da mesma |
BRPI0312002-3A BRPI0312002B1 (pt) | 2002-07-20 | 2003-07-18 | Composition for solubilization of paclitaxel and method of preparing the same |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0312002A BRPI0312002B8 (pt) | 2002-07-20 | 2003-07-18 | composição para solubilização de paclitaxel e método de preparação da mesma |
Country Status (12)
Country | Link |
---|---|
US (1) | US8075917B2 (pt) |
EP (1) | EP1545499B1 (pt) |
JP (1) | JP4744875B2 (pt) |
KR (1) | KR100533458B1 (pt) |
CN (1) | CN100544714C (pt) |
AU (1) | AU2003281465A1 (pt) |
BR (2) | BRPI0312002B8 (pt) |
CA (1) | CA2493336C (pt) |
HK (1) | HK1082674A1 (pt) |
RU (1) | RU2291693C2 (pt) |
WO (1) | WO2004009075A1 (pt) |
ZA (1) | ZA200409126B (pt) |
Families Citing this family (58)
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US9375203B2 (en) | 2002-03-25 | 2016-06-28 | Kieran Murphy Llc | Biopsy needle |
US7927368B2 (en) * | 2002-03-25 | 2011-04-19 | Kieran Murphy Llc | Device viewable under an imaging beam |
US20030181810A1 (en) * | 2002-03-25 | 2003-09-25 | Murphy Kieran P. | Kit for image guided surgical procedures |
KR100533460B1 (ko) * | 2002-07-20 | 2005-12-08 | 대화제약 주식회사 | 난용성 약물의 가용화용 점막흡착성 조성물, 이를 이용한난용성 약물의 가용화용 제형 및 이들의 제조 방법 |
US8178129B2 (en) | 2004-11-02 | 2012-05-15 | Tel-Aviv University Future Technology Development L.P. | Formulations of water insoluble or poorly water soluble drugs in lipidated glycosaminoglycan particles and their use for diagnostic and therapy |
EP1787645A1 (en) * | 2005-11-18 | 2007-05-23 | Institut Curie | New method for treating cancer based on the modulation of the calcineurin and/or the calcineurin/NFAT pathway |
KR100737742B1 (ko) * | 2005-12-05 | 2007-07-10 | 대화제약 주식회사 | 파클리탁셀 조성물의 제조 방법 |
CN101006997B (zh) * | 2006-01-26 | 2011-07-20 | 董英杰 | 复方紫杉醇及衍生物多西他赛脂肪乳剂和制备方法 |
JPWO2008041553A1 (ja) | 2006-09-26 | 2010-02-04 | アステラス製薬株式会社 | タクロリムス徐放性製剤 |
EP2119442A4 (en) | 2006-12-28 | 2010-12-15 | Astellas Pharma Inc | PHARMACEUTICAL COMPOSITION WITH TACROLIMUS MAINTAINED RELEASE |
WO2008098415A1 (fr) * | 2007-02-14 | 2008-08-21 | Beijing Century Biocom Pharmaceutical Technology Co., Ltd. | Composition pharmaceutique contenant du taxane et son procédé de préparation et d'application |
JP5135852B2 (ja) * | 2007-03-30 | 2013-02-06 | 日油株式会社 | 可溶化用組成物 |
CA3039251C (en) | 2008-11-10 | 2024-01-09 | Arbutus Biopharma Corporation | Novel lipids and compositions for the delivery of therapeutics |
EP2204167A1 (en) | 2009-01-05 | 2010-07-07 | Azad Pharma AG | Pharmaceutical microemulsion for preventing supramolecular aggregation of amphiphilic molecules |
CN101785757B (zh) * | 2009-01-22 | 2012-02-22 | 美迪思生物科技(北京)有限公司 | 一种紫杉醇自乳化制剂及其制备方法和用途 |
CN101926757B (zh) | 2010-09-01 | 2013-01-02 | 北京大学 | 一种难溶性药物的液体组合物及其制备方法 |
JP6184943B2 (ja) * | 2011-05-30 | 2017-08-23 | オートテリック エルエルシー | ポイント・オブ・ケア薬物動態プロフィールによる治療薬モニタリングおよび用量投与のための方法および組成物 |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
EP3936133A1 (en) | 2011-11-23 | 2022-01-12 | TherapeuticsMD, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
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JP6352258B2 (ja) * | 2012-07-16 | 2018-07-04 | センターズ フォー ディジーズ コントロール アンド プリベンション | 抗腫瘍薬による表面汚染に対する直接読み取り検出キット |
US9018246B2 (en) | 2012-09-05 | 2015-04-28 | Lp Pharmaceutical (Xiamen) Co., Ltd. | Transmucosal administration of taxanes |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
CA2947767A1 (en) | 2014-05-22 | 2015-11-26 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
EP3174542A4 (en) | 2014-07-29 | 2018-01-03 | TherapeuticsMD, Inc. | Transdermal cream |
ES2524248B2 (es) * | 2014-08-01 | 2015-07-03 | Lvd Biotech S.L. | Balón liberador de paclitaxel y procedimiento de fabricación del mismo |
KR101542364B1 (ko) * | 2014-10-31 | 2015-08-07 | 대화제약 주식회사 | 탁산을 포함하는 경구 투여용 약학 조성물 |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
KR101612257B1 (ko) | 2015-07-30 | 2016-04-20 | 대화제약 주식회사 | 고농도의 탁산을 포함하는 경구 투여용 약학 조성물 |
US10987335B2 (en) | 2015-07-30 | 2021-04-27 | Dae Hwa Pharma. Co., Ltd. | Pharmaceutical composition for oral administration comprising high concentration taxane |
RU2018113280A (ru) * | 2015-09-16 | 2019-10-16 | ДиЭфБи СОРИА, ЭлЭлСи | Доставка наночастиц лекарственного средства и способы их использования |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
BR112018070199A2 (pt) | 2016-04-01 | 2019-01-29 | Therapeuticsmd Inc | composição farmacêutica de hormônio esteroide |
CA3026108A1 (en) | 2016-06-10 | 2017-12-14 | Clarity Cosmetics Inc. | Non-comedogenic hair and scalp care formulations and method for use |
CN106620717B (zh) * | 2016-12-13 | 2020-11-24 | 上海交通大学 | 一种具有逆转肿瘤多药耐药性功能的两亲性缀合物抗肿瘤纳米药及其制备方法和应用 |
WO2018159941A1 (ko) * | 2017-03-02 | 2018-09-07 | 대화제약 주식회사 | 자나미비르를 포함하는 안정한 약제학적 조성물 |
KR101991661B1 (ko) * | 2017-03-02 | 2019-06-21 | 대화제약 주식회사 | 자나미비르를 포함하는 안정한 약제학적 조성물 |
EP3595633B1 (en) | 2017-03-15 | 2023-07-05 | DFB Soria, LLC | Topical therapy for the treatment of skin malignancies using nanoparticles of taxanes |
US11254773B2 (en) | 2017-05-11 | 2022-02-22 | The Regents Of The University Of California | Nanoscale multiple emulsions and nanoparticles |
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KR20200005110A (ko) * | 2018-07-05 | 2020-01-15 | 대화제약 주식회사 | 탁산-함유 약학 조성물을 함유하는 의약품의 안정성 개선방법 |
KR102093100B1 (ko) * | 2018-07-11 | 2020-03-26 | 대화제약 주식회사 | 산화 안정성이 향상된 탁산을 포함하는 경구용 약학 조성물 |
US11439586B2 (en) * | 2018-10-16 | 2022-09-13 | US Nano Food & Drug INC | Intratumour injection formulation |
CN109821055A (zh) * | 2019-02-01 | 2019-05-31 | 厦门大学 | 一种药物-碘油溶剂及其制备方法 |
KR20200142943A (ko) * | 2019-06-14 | 2020-12-23 | 대화제약 주식회사 | 항바이러스제를 포함하는 분말 제제 형태의 경구투여용 약학 조성물 |
KR102185475B1 (ko) | 2019-06-20 | 2020-12-02 | 대화제약 주식회사 | 이리노테칸 자유 염기를 포함하는 경구투여용 약학 조성물 |
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CN113244254B (zh) * | 2021-03-26 | 2023-03-14 | 浙江工业大学 | 一种增强金黄霉素a水溶性的组合物及其制备与应用 |
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KR100533460B1 (ko) * | 2002-07-20 | 2005-12-08 | 대화제약 주식회사 | 난용성 약물의 가용화용 점막흡착성 조성물, 이를 이용한난용성 약물의 가용화용 제형 및 이들의 제조 방법 |
-
2002
- 2002-07-20 KR KR10-2002-0042791A patent/KR100533458B1/ko active IP Right Grant
-
2003
- 2003-07-18 CN CNB038173468A patent/CN100544714C/zh not_active Expired - Lifetime
- 2003-07-18 JP JP2004522819A patent/JP4744875B2/ja not_active Expired - Lifetime
- 2003-07-18 EP EP03741592A patent/EP1545499B1/en not_active Expired - Lifetime
- 2003-07-18 US US10/521,669 patent/US8075917B2/en active Active
- 2003-07-18 WO PCT/KR2003/001427 patent/WO2004009075A1/en active Application Filing
- 2003-07-18 CA CA002493336A patent/CA2493336C/en not_active Expired - Lifetime
- 2003-07-18 RU RU2005104567/15A patent/RU2291693C2/ru active
- 2003-07-18 BR BRPI0312002A patent/BRPI0312002B8/pt active IP Right Grant
- 2003-07-18 BR BRPI0312002-3A patent/BRPI0312002B1/pt active IP Right Grant
- 2003-07-18 AU AU2003281465A patent/AU2003281465A1/en not_active Abandoned
-
2004
- 2004-11-11 ZA ZA2004/09126A patent/ZA200409126B/en unknown
-
2006
- 2006-02-03 HK HK06101474.7A patent/HK1082674A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP4744875B2 (ja) | 2011-08-10 |
ZA200409126B (en) | 2005-06-29 |
EP1545499A1 (en) | 2005-06-29 |
HK1082674A1 (en) | 2006-06-16 |
WO2004009075A1 (en) | 2004-01-29 |
US20060104999A1 (en) | 2006-05-18 |
BRPI0312002B8 (pt) | 2022-10-18 |
EP1545499A4 (en) | 2009-11-18 |
CA2493336C (en) | 2009-11-24 |
CA2493336A1 (en) | 2004-01-29 |
RU2291693C2 (ru) | 2007-01-20 |
CN1671370A (zh) | 2005-09-21 |
KR100533458B1 (ko) | 2005-12-07 |
KR20040009015A (ko) | 2004-01-31 |
JP2005538090A (ja) | 2005-12-15 |
BRPI0312002B1 (pt) | 2017-11-28 |
US8075917B2 (en) | 2011-12-13 |
AU2003281465A1 (en) | 2004-02-09 |
RU2005104567A (ru) | 2005-07-10 |
CN100544714C (zh) | 2009-09-30 |
EP1545499B1 (en) | 2013-02-20 |
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