BR0308321A - Inibidores da peptìdeo deformilase - Google Patents

Inibidores da peptìdeo deformilase

Info

Publication number
BR0308321A
BR0308321A BR0308321-7A BR0308321A BR0308321A BR 0308321 A BR0308321 A BR 0308321A BR 0308321 A BR0308321 A BR 0308321A BR 0308321 A BR0308321 A BR 0308321A
Authority
BR
Brazil
Prior art keywords
peptide deformylase
deformylase inhibitors
inhibitors
peptide
novel
Prior art date
Application number
BR0308321-7A
Other languages
English (en)
Inventor
Kelly M Aubart
Ajita Bhat
Siegfried B Chistensen Iv
Jack Dale Leber
Xiangmin Liao
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of BR0308321A publication Critical patent/BR0308321A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C07D233/78—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

"INIBIDORES DA PEPTìDEO DEFORMILASE". São fornecidos inibidores PDF inéditos e métodos inéditos para seu uso.
BR0308321-7A 2002-03-13 2003-03-13 Inibidores da peptìdeo deformilase BR0308321A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36442302P 2002-03-13 2002-03-13
PCT/US2003/007509 WO2003077913A1 (en) 2002-03-13 2003-03-13 Peptide deformylase inhibitors

Publications (1)

Publication Number Publication Date
BR0308321A true BR0308321A (pt) 2004-12-28

Family

ID=28041913

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0308321-7A BR0308321A (pt) 2002-03-13 2003-03-13 Inibidores da peptìdeo deformilase

Country Status (20)

Country Link
US (2) US20050124677A1 (pt)
EP (1) EP1482930B1 (pt)
JP (1) JP4471663B2 (pt)
KR (1) KR100980145B1 (pt)
CN (1) CN100336809C (pt)
AT (1) ATE514683T1 (pt)
AU (1) AU2003216554A1 (pt)
BR (1) BR0308321A (pt)
CA (1) CA2478331A1 (pt)
ES (1) ES2366396T3 (pt)
IL (1) IL163899A0 (pt)
IS (1) IS7441A (pt)
MX (1) MXPA04008799A (pt)
NO (1) NO328933B1 (pt)
NZ (1) NZ534839A (pt)
PL (1) PL371016A1 (pt)
RU (1) RU2287525C2 (pt)
TW (1) TWI294778B (pt)
WO (1) WO2003077913A1 (pt)
ZA (1) ZA200406973B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7208595B2 (en) * 2003-07-25 2007-04-24 The Ohio State University Research Foundation Peptide deformylase inhibitors as novel antibiotics
AU2006256937C1 (en) * 2005-06-07 2011-01-06 Novartis Ag Peptide deformylase (PDF) inhibitors 4
CN104130247B (zh) * 2007-08-21 2018-06-01 塞诺米克斯公司 人t2r苦味受体及其用途
DE102009045969B4 (de) * 2009-10-23 2019-01-31 Technische Universität Bergakademie Freiberg Verfahren und Mittel zur Spaltung von Estern, Amiden und Thioestern der Ameisensäure

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW448172B (en) * 1996-03-08 2001-08-01 Pharmacia & Upjohn Co Llc Novel hydroxamic acid derivatives useful for the treatment of diseases related to connective tissue degradation
JP3382127B2 (ja) * 1996-07-04 2003-03-04 エフ．ホフマン−ラ ロシュ アーゲー キラルなコハク酸誘導体の製造方法
WO2000059285A2 (en) * 1999-04-02 2000-10-12 Du Pont Pharmaceuticals Company NOVEL LACTAM INHIBITORS OF MATRIX METALLOPROTEINASES, TNF-α, AND AGGRECANASE
WO2002028829A2 (en) 2000-09-25 2002-04-11 Questcor Pharmaceuticals, Inc. Peptide deformylase inhibitors
US6825215B2 (en) * 2001-01-11 2004-11-30 Bristol-Myers Squibb Pharma Company 1,1-disubstituted cyclic inhibitors of matrix metalloproteases and TNF-α

Also Published As

Publication number Publication date
ATE514683T1 (de) 2011-07-15
PL371016A1 (en) 2005-06-13
KR100980145B1 (ko) 2010-09-03
MXPA04008799A (es) 2004-11-26
NO328933B1 (no) 2010-06-21
CN1652775A (zh) 2005-08-10
CN100336809C (zh) 2007-09-12
RU2004130454A (ru) 2005-04-10
TWI294778B (en) 2008-03-21
AU2003216554A1 (en) 2003-09-29
TW200405810A (en) 2004-04-16
CA2478331A1 (en) 2003-09-25
EP1482930A4 (en) 2006-06-28
ES2366396T3 (es) 2011-10-19
JP2005525383A (ja) 2005-08-25
US20050124677A1 (en) 2005-06-09
EP1482930A1 (en) 2004-12-08
NZ534839A (en) 2006-09-29
IS7441A (is) 2004-09-08
JP4471663B2 (ja) 2010-06-02
IL163899A0 (en) 2005-12-18
RU2287525C2 (ru) 2006-11-20
KR20040091120A (ko) 2004-10-27
ZA200406973B (en) 2005-06-23
EP1482930B1 (en) 2011-06-29
US20070155810A1 (en) 2007-07-05
WO2003077913A1 (en) 2003-09-25
US7745637B2 (en) 2010-06-29
NO20044186L (no) 2004-09-30

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA:INT.CI. A61K 31/4166, C07D 233/78, A61P 31/04

Ipc: A61K 31/4166 (2011.01), C07D 233/78 (2011.01), A61

B25D Requested change of name of applicant approved

Owner name: GLAXOSMITHKLINE LLC (US)

Free format text: NOME ALTERADO DE: SMITHKLINE BEECHAM CORPORATION

B08L Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette]

Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 10A E 11A ANUIDADES.

B08I Publication cancelled [chapter 8.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2258 DE 15/04/2014 POR TER SIDO INDEVIDA.

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 10A, 11A, 12A, 13A, 14A, 15A, 16A E 17A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.