BR0214864A - Processo para a preparação de 4-metil-7-aminoquinolonas - Google Patents

Processo para a preparação de 4-metil-7-aminoquinolonas

Info

Publication number
BR0214864A
BR0214864A BR0214864-1A BR0214864A BR0214864A BR 0214864 A BR0214864 A BR 0214864A BR 0214864 A BR0214864 A BR 0214864A BR 0214864 A BR0214864 A BR 0214864A
Authority
BR
Brazil
Prior art keywords
radical
group
alkyl
compound
hydrogen atom
Prior art date
Application number
BR0214864-1A
Other languages
English (en)
Inventor
Johannes Benkhoff
Bernd Lamatsch
Original Assignee
Ciba Sc Holding Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Sc Holding Ag filed Critical Ciba Sc Holding Ag
Publication of BR0214864A publication Critical patent/BR0214864A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Quinoline Compounds (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE 4-METIL-7-AMINOQUINOLONAS". A presente invenção refere-se a um processo para a preparação de um composto da fórmula geral que compreende converter um composto da fórmula geral em um solvente orgânico aprótico na presença de uma quantidade cataliticamente ativa de um ácido forte (catalisador) ou de um agente que libera um ácido forte ou de um sal de amónio de um ácido forte, sendo também possível para o catalisador fazer parte do produto/material de partida, em um composto da fórmula I, em que R^ 5^, R^ 6^ e R^ 8^ são, cada um, independentemente dos outros, um átomo de hidrogênio, um grupo nitro, um grupo sulfo, um átomo de halogênio, um pseudo-halogênio, um grupo COOR^ 1^ ou CONHR^ 2^ ou um radical de C~ 1-8~alquila, C~ 1-8~alcóxi ou arilóxi, um grupo amida, um radical de tioalquila ou tioarila, um radical de alquil- ou aril-sulfonila, um radical de alquil- ou arilsulfinila, um grupo trifluorometila ou um grupo fosfono, R^ 1^ e R^ 2^ sendo um átomo de hidrogênio ou um radical C~ 1-8~alquila ou um radical de arila ou aralquila, R^ 10^ é um grupo -C(O)CH~ 2~C(O)CH~ 3~ e R^ 11^ é um átomo de hidrogênio ou um radical de acila, ou R^ 10^ e R^ 11^ são um grupo -C(O)CH~ 2~C(O)CH~ 3~. O processo de acordo com a invenção é simples de executar e resulta em produtos de pureza química alta e pureza isomérica alta em um rendimento alto.
BR0214864-1A 2001-12-11 2002-12-03 Processo para a preparação de 4-metil-7-aminoquinolonas BR0214864A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01811206 2001-12-11
PCT/EP2002/013663 WO2003050089A1 (en) 2001-12-11 2002-12-03 Process for the preparation of 4-methyl-7-aminoquinolones

Publications (1)

Publication Number Publication Date
BR0214864A true BR0214864A (pt) 2004-12-14

Family

ID=8184301

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0214864-1A BR0214864A (pt) 2001-12-11 2002-12-03 Processo para a preparação de 4-metil-7-aminoquinolonas

Country Status (10)

Country Link
US (1) US7144993B2 (pt)
EP (1) EP1453809A1 (pt)
JP (1) JP2005518373A (pt)
KR (1) KR20040065577A (pt)
CN (1) CN100374423C (pt)
AU (1) AU2002358085A1 (pt)
BR (1) BR0214864A (pt)
CA (1) CA2467511A1 (pt)
MX (1) MXPA04005213A (pt)
WO (1) WO2003050089A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10107813A1 (de) * 2001-02-20 2002-09-05 Bosch Gmbh Robert Drucksensormodul
US7459469B2 (en) 2004-11-10 2008-12-02 Targacept, Inc. Hydroxybenzoate salts of metanicotine compounds
CN103232389A (zh) * 2013-05-08 2013-08-07 浙江新三和医药化工股份有限公司 2-氯甲基-4-甲氧基-3,5-二甲基吡啶盐酸盐的制备方法
US11345873B2 (en) * 2019-08-14 2022-05-31 Valvoline Licensing And Intellectual Property Llc Lubricant composition containing ashless TBN molecules
CN114907260A (zh) * 2022-05-27 2022-08-16 河南省科学院高新技术研究中心 一种利用离子液体制备4-溴甲基喹啉酮的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2152786A (en) * 1936-07-09 1939-04-04 Carbide & Carbon Chem Corp Preparation of acetoacetyl aromatic acid amides
US2311054A (en) * 1939-06-30 1943-02-16 Eastman Kodak Co Preparation of amino compounds
US2688543A (en) * 1950-12-20 1954-09-07 Gen Aniline & Film Corp Poly-acetoacetyl derivatives of polyamines as azo components in diazotype photoprinting material
DE958647C (de) * 1952-12-28 1957-02-21 Hoechst Ag Verfahren zur Herstellung von 7-Amino-2-oxy-4-methyl-chinolinen
US2936306A (en) 1957-05-17 1960-05-10 Ciba Ltd Azo-dyestuffs
US3119808A (en) * 1960-11-14 1964-01-28 Ici Ltd 7-(monoacetoacet monoarylide)-azo-4-methyl-2-hydroxy-quinoline coloring matters
DE1278039B (de) * 1960-11-18 1968-09-19 Ici Ltd Verfahren zur Herstellung von Azofarbstoffen
US3304328A (en) * 1963-10-25 1967-02-14 Fmc Corp Preparation of acetoacetarylamides
FR1451064A (fr) * 1965-10-22 1966-06-24 Fmc Corp Procédé d'obtention d'acéto-acétarylamides en milieu aqueux
US3933886A (en) 1971-10-04 1976-01-20 Henkel & Cie Gmbh Diamino-nitro-benzene compounds
US3907494A (en) * 1971-10-04 1975-09-23 Therachemie Chem Therapeut Hair dyes based on diamino-nitro-benzene compounds
DE2149467A1 (de) * 1971-10-04 1973-04-12 Therachemie Chem Therapeut Haarfaerbemittel
US4064131A (en) 1973-09-20 1977-12-20 Lonza, Ltd. Process for the production of 1,2-dihydro-2-oxo-4-methyl-7-acetoacetic acid amido-quinoline
JPS5058080A (pt) * 1973-09-20 1975-05-20
FR2286813A1 (fr) * 1974-10-03 1976-04-30 Roussel Uclaf Nouveaux crotonanilides substitues, procede de preparation et compositions pesticides les contenant
DE2519036A1 (de) * 1975-04-29 1976-11-11 Hoechst Ag Verfahren zur herstellung von acetoacetylarylamiden
DE3604050A1 (de) * 1986-02-08 1987-08-13 Boehringer Mannheim Gmbh Thioether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
JPS62215660A (ja) * 1986-03-17 1987-09-22 Nippon Kayaku Co Ltd アゾ化合物及びそれを用いる基材の染色法

Also Published As

Publication number Publication date
EP1453809A1 (en) 2004-09-08
CN1602301A (zh) 2005-03-30
CA2467511A1 (en) 2003-06-19
CN100374423C (zh) 2008-03-12
JP2005518373A (ja) 2005-06-23
AU2002358085A1 (en) 2003-06-23
US20050222397A1 (en) 2005-10-06
KR20040065577A (ko) 2004-07-22
WO2003050089A1 (en) 2003-06-19
MXPA04005213A (es) 2004-08-19
US7144993B2 (en) 2006-12-05

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]